Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors von Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizawa, Masakuni, Akiyama, Yasuto, Kusuhara, Masatoshi, Mochizuki, Tohru, Sugino, Takashi, Shiomi, Akio, Tsubosa, Yasuhiro, Uesaka, Katsuhiko, Terashima, Masanori, Yamaguchi, Ken

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Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors von Ohshima, Keiichi, Hatakeyama, Keiichi, Nagashima, Takeshi, Watanabe, Yuko, Kanto, Kaori, Doi, Yuki, Ide, Tomomi, Shimoda, Yuji, Tanabe, Tomoe, Ohnami, Sumiko, Ohnami, Shumpei, Serizawa, Masakuni, Maruyama, Koji, Akiyama, Yasuto, Urakami, Kenichi, Kusuhara, Masatoshi, Mochizuki, Tohru, Yamaguchi, Ken

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Disclosure of secondary findings in exome sequencing of 2480 Japanese cancer patients von Horiuchi, Yasue, Matsubayashi, Hiroyuki, Kiyozumi, Yoshimi, Nishimura, Seiichiro, Higashigawa, Satomi, Kado, Nobuhiro, Nagashima, Takeshi, Mizuguchi, Maki, Ohnami, Sumiko, Arai, Makoto, Urakami, Kenichi, Kusuhara, Masatoshi, Yamaguchi, Ken

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BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer von Ohnami, Shumpei, Maruyama, Kouji, Chen, Kai, Takahashi, Yu, Hatakeyama, Keiichi, Ohshima, Keiichi, Shimoda, Yuji, Sakai, Ai, Kamada, Fukumi, Nakatani, Sou, Naruoka, Akane, Ohnami, Sumiko, Kusuhara, Masatoshi, Akiyama, Yasuto, Kagawa, Hiroyasu, Shiomi, Akio, Nagashima, Takeshi, Urakami, Kenichi, Yamaguchi, Ken

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Japanese version of The Cancer Genome Atlas, JCGA, established using fresh frozen tumors obtained from 5143 cancer patients von Nagashima, Takeshi, Yamaguchi, Ken, Urakami, Kenichi, Shimoda, Yuji, Ohnami, Sumiko, Ohshima, Keiichi, Tanabe, Tomoe, Naruoka, Akane, Kamada, Fukumi, Serizawa, Masakuni, Hatakeyama, Keiichi, Matsumura, Kenya, Ohnami, Shumpei, Maruyama, Koji, Mochizuki, Tohru, Kusuhara, Masatoshi, Shiomi, Akio, Ohde, Yasuhisa, Terashima, Masanori, Uesaka, Katsuhiko, Onitsuka, Tetsuro, Nishimura, Seiichiro, Hirashima, Yasuyuki, Hayashi, Nakamasa, Kiyohara, Yoshio, Tsubosa, Yasuhiro, Katagiri, Hirohisa, Niwakawa, Masashi, Takahashi, Kaoru, Kashiwagi, Hiroya, Nakagawa, Masahiro, Ishida, Yuji, Sugino, Takashi, Takahashi, Mitsuru, Akiyama, Yasuto

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Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy von Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Serizawa, Masakuni, Maruyama, Koji, Naruoka, Akane, Akiyama, Yasuto, Urakami, Kenichi, Kusuhara, Masatoshi, Mochizuki, Tohru, Yamaguchi, Ken

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Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content von Hatakeyama, Keiichi, Muramatsu, Koji, Nagashima, Takeshi, Ichida, Hiroyuki, Kawanishi, Yuichi, Fukumura, Ryutaro, Ohshima, Keiichi, Shimoda, Yuji, Ohnami, Sumiko, Ohnami, Shumpei, Maruyama, Koji, Naruoka, Akane, Kenmotsu, Hirotsugu, Urakami, Kenichi, Akiyama, Yasuto, Sugino, Takashi, Yamaguchi, Ken

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Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients von Hatakeyama, Keiichi, Nagashima, Takeshi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken

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A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population von Shiraishi, Kouya, Kunitoh, Hideo, Daigo, Yataro, Takahashi, Atsushi, Goto, Koichi, Sakamoto, Hiromi, Ohnami, Sumiko, Shimada, Yoko, Ashikawa, Kyota, Saito, Akira, Watanabe, Shun-ichi, Tsuta, Koji, Kamatani, Naoyuki, Yoshida, Teruhiko, Nakamura, Yusuke, Yokota, Jun, Kubo, Michiaki, Kohno, Takashi

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Tumor mutational burden analysis of 2,000 Japanese cancer genomes using whole exome and targeted gene panel sequencing von HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, URAKAMI, Kenichi, OHSHIMA, Keiichi, SERIZAWA, Masakuni, OHNAMI, Sumiko, SHIMODA, Yuji, OHNAMI, Shumpei, MARUYAMA, Koji, NARUOKA, Akane, AKIYAMA, Yasuto, KUSUHARA, Masatoshi, MOCHIZUKI, Tohru, YAMAGUCHI, Ken

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JCGA: the Japanese version of the Cancer Genome Atlas and its contribution to the interpretation of gene alterations detected in clinical cancer genome sequencing von Serizawa, Masakuni, Mizuguchi, Maki, Urakami, Kenichi, Nagashima, Takeshi, Ohshima, Keiichi, Hatakeyama, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Maruyama, Koji, Ashizawa, Tadashi, Iizuka, Akira, Horiuchi, Yasue, Naruoka, Akane, Kenmotsu, Hirotsugu, Akiyama, Yasuto, Yamaguchi, Ken

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Evaluation of whole genome sequencing utility in identifying driver alterations in cancer genome von Nagashima, Takeshi, Yamaguchi, Ken, Urakami, Kenichi, Shimoda, Yuji, Ohnami, Sumiko, Ohshima, Keiichi, Tanabe, Tomoe, Naruoka, Akane, Kamada, Fukumi, Serizawa, Masakuni, Hatakeyama, Keiichi, Ohnami, Shumpei, Maruyama, Koji, Mochizuki, Tohru, Mizuguchi, Maki, Shiomi, Akio, Ohde, Yasuhisa, Bando, Etsuro, Sugiura, Teiichi, Mukaigawa, Takashi, Nishimura, Seiichiro, Hirashima, Yasuyuki, Mitsuya, Koichi, Yoshikawa, Shusuke, Kiyohara, Yoshio, Tsubosa, Yasuhiro, Katagiri, Hirohisa, Niwakawa, Masashi, Takahashi, Kaoru, Kashiwagi, Hiroya, Yasunaga, Yoshichika, Ishida, Yuji, Sugino, Takashi, Kenmotsu, Hirotsugu, Terashima, Masanori, Takahashi, Mitsuru, Uesaka, Katsuhiko, Akiyama, Yasuto

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Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes von Ohnami, Sumiko, Naruoka, Akane, Isaka, Mitsuhiro, Mizuguchi, Maki, Nakatani, Sou, Kamada, Fukumi, Shimoda, Yuji, Sakai, Ai, Ohshima, Keiichi, Hatakeyama, Keiichi, Maruyama, Kouji, Ohde, Yasuhisa, Kenmotsu, Hirotsugu, Takahashi, Toshiaki, Akiyama, Yasuto, Nagashima, Takeshi, Urakami, Kenichi, Ohnami, Shumpei, Yamaguchi, Ken

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Development of two 410-cancer-gene panel tests for solid tumors and liquid biopsy based on genome data of 5,143 Japanese cancer patients von SHIMODA, Yuji, NAGASHIMA, Takeshi, URAKAMI, Kenichi, KAMADA, Fukumi, NAKATANI, Sou, MIZUGUCHI, Maki, SERIZAWA, Masakuni, HATAKEYAMA, Keiichi, OHSHIMA, Keiichi, MOCHIZUKI, Tohru, OHNAMI, Sumiko, OHNAMI, Shumpei, KAWAKAMI, Takeshi, YAMAZAKI, Kentaro, MURAKAMI, Haruyasu, KENMOTSU, Hirotsugu, SHIOMI, Akio, AKIYAMA, Yasuto, YAMAGUCHI, Ken

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Mutational concordance analysis provides supportive information for double cancer diagnosis von Hatakeyama, Keiichi, Nagashima, Takeshi, Notsu, Akifumi, Ohshima, Keiichi, Ohnami, Sumiko, Ohnami, Shumpei, Shimoda, Yuji, Naruoka, Akane, Maruyama, Koji, Iizuka, Akira, Ashizawa, Tadashi, Kenmotsu, Hirotsugu, Mochizuki, Tohru, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken

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Role of Tumor Mutation Burden Analysis in Detecting Lynch Syndrome in Precision Medicine: Analysis of 2,501 Japanese Cancer Patients von Kiyozumi, Yoshimi, Matsubayashi, Hiroyuki, Higashigawa, Satomi, Horiuchi, Yasue, Kado, Nobuhiro, Hirashima, Yasuyuki, Shiomi, Akio, Oishi, Takuma, Ohnami, Sumiko, Ohshima, Keiichi, Urakami, Kenichi, Nagashima, Takeshi, Yamaguchi, Ken

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Multilayer‐omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome von Arai, Eri, Sakamoto, Hiromi, Ichikawa, Hitoshi, Totsuka, Hirohiko, Chiku, Suenori, Gotoh, Masahiro, Mori, Taisuke, Nakatani, Tamao, Ohnami, Sumiko, Nakagawa, Tohru, Fujimoto, Hiroyuki, Wang, Linghua, Aburatani, Hiroyuki, Yoshida, Teruhiko, Kanai, Yae

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Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma von Imamura, Taisuke, Okamura, Yukiyasu, Ohshima, Keiichi, Uesaka, Katsuhiko, Sugiura, Teiichi, Ito, Takaaki, Yamamoto, Yusuke, Ashida, Ryo, Ohgi, Katsuhisa, Otsuka, Shimpei, Ohnami, Sumiko, Nagashima, Takeshi, Hatakeyama, Keiichi, Sugino, Takashi, Urakami, Kenichi, Akiyama, Yasuto, Yamaguchi, Ken

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Genomic landscape of pancreatic cancer in the Japanese version of the Cancer Genome Atlas von Imamura, Taisuke, Ashida, Ryo, Ohshima, Keiichi, Uesaka, Katsuhiko, Sugiura, Teiichi, Okamura, Yukiyasu, Ohgi, Katsuhisa, Ohnami, Sumiko, Nagashima, Takeshi, Yamaguchi, Ken

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Impact of somatic mutations and transcriptomic alterations on cancer aneuploidy von HATAKEYAMA, Keiichi, NAGASHIMA, Takeshi, OHSHIMA, Keiichi, OHNAMI, Sumiko, OHNAMI, Shumpei, SHIMODA, Yuji, NARUOKA, Akane, MARUYAMA, Koji, IIZUKA, Akira, ASHIZAWA, Tadashi, KENMOTSU, Hirotsugu, MOCHIZUKI, Tohru, URAKAMI, Kenichi, AKIYAMA, Yasuto, YAMAGUCHI, Ken

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