Sphingolipid metabolism in cancer signalling and therapy von Ogretmen, Besim

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Sphingolipids in cancer: Regulation of pathogenesis and therapy von Ogretmen, Besim

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Diverse Functions of Ceramide in Cancer Cell Death and Proliferation von Saddoughi, Sahar A., Ogretmen, Besim

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Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma von Qie, Shuo, Yoshida, Akihiro, Parnham, Stuart, Oleinik, Natalia, Beeson, Gyda C., Beeson, Craig C., Ogretmen, Besim, Bass, Adam J., Wong, Kwok-Kin, Rustgi, Anil K., Diehl, J. Alan

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Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients von Janneh, Alhaji H., Kassir, Mohamed Faisal, Dwyer, Connor J., Chakraborty, Paramita, Pierce, Jason S., Flume, Patrick A., Li, Hong, Nadig, Satish N., Mehrotra, Shikhar, Ogretmen, Besim

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A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors von Britten, Carolyn D, Garrett-Mayer, Elizabeth, Chin, Steven H, Shirai, Keisuke, Ogretmen, Besim, Bentz, Tricia A, Brisendine, Alan, Anderton, Kate, Cusack, Susan L, Maines, Lynn W, Zhuang, Yan, Smith, Charles D, Thomas, Melanie B

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Biologically active sphingolipids in cancer pathogenesis and treatment von Hannun, Yusuf A, Ogretmen, Besim

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Regulation of PP2A by Sphingolipid Metabolism and Signaling von Oaks, Joshua, Ogretmen, Besim

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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity von Chakraborty, Paramita, Vaena, Silvia G., Thyagarajan, Krishnamurthy, Chatterjee, Shilpak, Al-Khami, Amir, Selvam, Shanmugam Panneer, Nguyen, Hung, Kang, Inhong, Wyatt, Megan W., Baliga, Uday, Hedley, Zachariah, Ngang, Rose N., Guo, Beichu, Beeson, Gyda C., Husain, Shahid, Paulos, Chrystal M., Beeson, Craig C., Zilliox, Michael J., Hill, Elizabeth G., Mehrotra, Meenal, Yu, Xue-Zhong, Ogretmen, Besim, Mehrotra, Shikhar

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Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation von Panneer Selvam, Shanmugam, De Palma, Ryan M, Oaks, Joshua J, Oleinik, Natalia, Peterson, Yuri K, Stahelin, Robert V, Skordalakes, Emmanuel, Ponnusamy, Suriyan, Garrett-Mayer, Elizabeth, Smith, Charles D, Ogretmen, Besim

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PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells von Neviani, Paolo, Harb, Jason G, Oaks, Joshua J, Santhanam, Ramasamy, Walker, Christopher J, Ellis, Justin J, Ferenchak, Gregory, Dorrance, Adrienne M, Paisie, Carolyn A, Eiring, Anna M, Ma, Yihui, Mao, Hsiaoyin C, Zhang, Bin, Wunderlich, Mark, May, Philippa C, Sun, Chaode, Saddoughi, Sahar A, Bielawski, Jacek, Blum, William, Klisovic, Rebecca B, Solt, Janelle A, Byrd, John C, Volinia, Stefano, Cortes, Jorge, Huettner, Claudia S, Koschmieder, Steffen, Holyoake, Tessa L, Devine, Steven, Caligiuri, Michael A, Croce, Carlo M, Garzon, Ramiro, Ogretmen, Besim, Arlinghaus, Ralph B, Chen, Ching-Shih, Bittman, Robert, Hokland, Peter, Roy, Denis-Claude, Milojkovic, Dragana, Apperley, Jane, Goldman, John M, Reid, Alistair, Mulloy, James C, Bhatia, Ravi, Marcucci, Guido, Perrotti, Danilo

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CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress von Fekry, Baharan, Jeffries, Kristen A., Esmaeilniakooshkghazi, Amin, Ogretmen, Besim, Krupenko, Sergey A., Krupenko, Natalia I.

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Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response von Vaena, Silvia, Chakraborty, Paramita, Lee, Han Gyul, Janneh, Alhaji H., Kassir, Mohamed Faisal, Beeson, Gyda, Hedley, Zachariah, Yalcinkaya, Ahmet, Sofi, M. Hanief, Li, Hong, Husby, Monica L., Stahelin, Robert V., Yu, Xue-Zhong, Mehrotra, Shikhar, Ogretmen, Besim

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Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma von Kummetha Venkata, Jagadish, An, Ningfei, Stuart, Robert, Costa, Luciano J., Cai, Houjian, Coker, Woodrow, Song, Jin H., Gibbs, Kiwana, Matson, Terri, Garrett-Mayer, Elizabeth, Wan, Zhuang, Ogretmen, Besim, Smith, Charles, Kang, Yubin

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Sphingolipid metabolism in T cell responses after allogeneic hematopoietic cell transplantation von Tian, Linlu, Ogretmen, Besim, Chung, Brian Y., Yu, Xue-Zhong

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Polyploid giant cancer cells are dependent on cholesterol for progeny formation through amitotic division von White-Gilbertson, Shai, Lu, Ping, Esobi, Ikechukwu, Echesabal-Chen, Jing, Mulholland, Patrick J., Gooz, Monika, Ogretmen, Besim, Stamatikos, Alexis, Voelkel-Johnson, Christina

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The NMR‐based characterization of the FTY720‐SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET‐PP2A interaction von De Palma, Ryan M., Parnham, Stuart R., Li, Yitong, Oaks, Joshua J., Peterson, Yuri K., Szulc, Zdzislaw M., Roth, Braden M., Xing, Yongna, Ogretmen, Besim

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Ceramide Synthase 6 Deficiency Enhances Inflammation in the DSS model of Colitis von Helke, Kristi, Angel, Peggi, Lu, Ping, Garrett-Mayer, Elizabeth, Ogretmen, Besim, Drake, Richard, Voelkel-Johnson, Christina

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Smoking-induced control of miR-133a-3p alters the expression of EGFR and HuR in HPV-infected oropharyngeal cancer von House, Reniqua, Majumder, Mrinmoyee, Janakiraman, Harinarayan, Ogretmen, Besim, Kato, Masanari, Erkul, Evren, Hill, Elizabeth, Atkinson, Carl, Barth, Jeremy, Day, Terrence A, Palanisamy, Viswanathan

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Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis von Saddoughi, Sahar A., Gencer, Salih, Peterson, Yuri K., Ward, Katherine E., Mukhopadhyay, Archana, Oaks, Joshua, Bielawski, Jacek, Szulc, Zdzislaw M., Thomas, Raquela J., Selvam, Shanmugam P., Senkal, Can E., Garrett‐Mayer, Elizabeth, De Palma, Ryan M., Fedarovich, Dzmitry, Liu, Angen, Habib, Amyn A., Stahelin, Robert V., Perrotti, Danilo, Ogretmen, Besim

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