Pharmacogenomic‐Guided Therapy in Colorectal Cancer von Diasio, Robert B., Innocenti, Federico, Offer, Steven M.

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Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy von Diasio, Robert B, Offer, Steven M

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Is It Finally Time for a Personalized Medicine Approach for Fluorouracil-Based Therapies? von Offer, Steven M, Diasio, Robert B

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update von Amstutz, Ursula, Henricks, Linda M., Offer, Steven M., Barbarino, Julia, Schellens, Jan H.M., Swen, Jesse J., Klein, Teri E., McLeod, Howard L., Caudle, Kelly E., Diasio, Robert B., Schwab, Matthias

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BEDwARS: a robust Bayesian approach to bulk gene expression deconvolution with noisy reference signatures von Ghaffari, Saba, Bouchonville, Kelly J, Saleh, Ehsan, Schmidt, Remington E, Offer, Steven M, Sinha, Saurabh

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Comparative Functional Analysis of DPYD Variants of Potential Clinical Relevance to Dihydropyrimidine Dehydrogenase Activity von OFFER, Steven M, FOSSUM, Croix C, WEGNER, Natalie J, STUFLESSER, Alexander J, BUTTERFIELD, Gabriel L, DIASIO, Robert B

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Phenotypic Profiling of DPYD Variations Relevant to 5-Fluorouracil Sensitivity Using Real-time Cellular Analysis and In Vitro Measurement of Enzyme Activity von OFFER, Steven M, WEGNER, Natalie J, FOSSUM, Croix, KANGSHENG WANG, DIASIO, Robert B

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An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes von Ghaffari, Saba, Hanson, Casey, Schmidt, Remington E, Bouchonville, Kelly J, Offer, Steven M, Sinha, Saurabh

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A phosphotyrosine switch regulates organic cation transporters von Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh

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microRNAs miR-27a and miR-27b directly regulate liver dihydropyrimidine dehydrogenase expression through two conserved binding sites von Offer, Steven M, Butterfield, Gabriel L, Jerde, Calvin R, Fossum, Croix C, Wegner, Natalie J, Diasio, Robert B

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Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy von Shrestha, Shikshya, Offer, Steven M.

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Response to “DPYD genotyping panels: Impact of population diversity” von Gaedigk, Andrea, Turner, Amy J., Haidar, Cyrine E., Empey, Philip E., Offer, Steven M.

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Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing von Turner, Amy J., Haidar, Cyrine E., Yang, Wenjian, Boone, Erin C., Offer, Steven M., Empey, Philip E., Haddad, Andrew, Tahir, Saba, Scharer, Gunter, Broeckel, Ulrich, Gaedigk, Andrea

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Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase ( DPYD ) von Zhang, Ting, Ambrodji, Alisa, Huang, Huixing, Bouchonville, Kelly J, Etheridge, Amy S, Schmidt, Remington E, Bembenek, Brianna M, Temesgen, Zoey B, Wang, Zhiquan, Innocenti, Federico, Stroka, Deborah, Diasio, Robert B, Largiadèr, Carlo R, Offer, Steven M

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Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter von Wu, Rentian, Nie, Qian, Tapper, Erin E, Jerde, Calvin R, Dunlap, Garrett S, Shrestha, Shikshya, Elraiyah, Tarig A, Offer, Steven M, Diasio, Robert B

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Defining Proximity Proteome of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling von Li, Xinran, Zhou, Jiaqi, Zhao, Wenjuan, Wen, Qing, Wang, Weijie, Peng, Huipai, Gao, Yuan, Bouchonville, Kelly J., Offer, Steven M., Chan, Kuiming, Wang, Zhiquan, Li, Nan, Gan, Haiyun

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A DPYD Variant (Y186C) Specific to Individuals of African Descent in a Patient With Life-Threatening 5-FU Toxic Effects: Potential for an Individualized Medicine Approach von Saif, Muhammad Wasif, MD, Lee, Adam M., PhD, Offer, Steven M., PhD, McConnell, Kathleen, RN, Relias, Valerie, PharmD, Diasio, Robert B., MD

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Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID von Offer, Steven M, Pan-Hammarström, Qiang, Hammarström, Lennart, Harris, Reuben S

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Chromatin assembly factor 1 suppresses epigenetic reprogramming toward adaptive drug resistance von Wang, Zhiquan, Wu, Rentian, Nie, Qian, Bouchonville, Kelly J., Diasio, Robert B., Offer, Steven M.

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Gene‐Specific Variant Classifier (DPYD‐Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase von Shrestha, Shikshya, Zhang, Cheng, Jerde, Calvin R., Nie, Qian, Li, Hu, Offer, Steven M., Diasio, Robert B.

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