Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation von Wattenberg, Max M., Asch, Daniella, Yu, Shun, O’Dwyer, Peter J., Domchek, Susan M., Nathanson, Katherine L., Rosen, Mark A., Beatty, Gregory L., Siegelman, Evan S., Reiss, Kim A.

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Modified Eligibility Criteria: Patient Access and Subpopulation Applicability vs Efficiency in Drug Development von O'Dwyer, Peter J

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Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) von Flaherty, Keith T, Gray, Robert J, Chen, Alice P, Li, Shuli, McShane, Lisa M, Patton, David, Hamilton, Stanley R, Williams, P Mickey, Iafrate, A John, Sklar, Jeffrey, Mitchell, Edith P, Harris, Lyndsay N, Takebe, Naoko, Sims, David J, Coffey, Brent, Fu, Tony, Routbort, Mark, Zwiebel, James A, Rubinstein, Larry V, Little, Richard F, Arteaga, Carlos L, Comis, Robert, Abrams, Jeffrey S, O'Dwyer, Peter J, Conley, Barbara A

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Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors von El-Khoueiry, Anthony B., Clarke, James, Neff, Tobias, Crossman, Tim, Ratia, Nirav, Rathi, Chetan, Noto, Paul, Tarkar, Aarti, Garrido-Laguna, Ignacio, Calvo, Emiliano, Rodón, Jordi, Tran, Ben, O’Dwyer, Peter J., Cuker, Adam, Abdul Razak, Albiruni R.

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Phase 2 study of vismodegib, a hedgehog inhibitor, combined with gemcitabine and nab-paclitaxel in patients with untreated metastatic pancreatic adenocarcinoma von De Jesus-Acosta, Ana, Sugar, Elizabeth A., O’Dwyer, Peter J., Ramanathan, Ramesh K., Von Hoff, Daniel D., Rasheed, Zeshaan, Zheng, Lei, Begum, Asma, Anders, Robert, Maitra, Anirban, McAllister, Florencia, Rajeshkumar, N. V., Yabuuchi, Shinichi, de Wilde, Roeland F., Batukbhai, Bhavina, Sahin, Ismet, Laheru, Daniel A.

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CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans von Beatty, Gregory L., Chiorean, Elena G., Fishman, Matthew P., Saboury, Babak, Teitelbaum, Ursina R., Sun, Weijing, Huhn, Richard D., Song, Wenru, Li, Dongguang, Sharp, Leslie L., Torigian, Drew A., O'Dwyer, Peter J., Vonderheide, Robert H.

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Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy von Sherman, Mara H., Yu, Ruth T., Engle, Dannielle D., Ding, Ning, Atkins, Annette R., Tiriac, Herve, Collisson, Eric A., Connor, Frances, Van Dyke, Terry, Kozlov, Serguei, Martin, Philip, Tseng, Tiffany W., Dawson, David W., Donahue, Timothy R., Masamune, Atsushi, Shimosegawa, Tooru, Apte, Minoti V., Wilson, Jeremy S., Ng, Beverly, Lau, Sue Lynn, Gunton, Jenny E., Wahl, Geoffrey M., Hunter, Tony, Drebin, Jeffrey A., O’Dwyer, Peter J., Liddle, Christopher, Tuveson, David A., Downes, Michael, Evans, Ronald M.

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The NCI-MATCH trial: lessons for precision oncology von O’Dwyer, Peter J., Gray, Robert J., Flaherty, Keith T., Chen, Alice P., Li, Shuli, Wang, Victoria, McShane, Lisa M., Patton, David R., Tricoli, James V., Williams, P. Mickey, Iafrate, A. John, Sklar, Jeffrey, Mitchell, Edith P., Takebe, Naoko, Sims, David J., Coffey, Brent, Fu, Tony, Routbort, Mark, Rubinstein, Larry V., Little, Richard F., Arteaga, Carlos L., Marinucci, Donna, Hamilton, Stanley R., Conley, Barbara A., Harris, Lyndsay N., Doroshow, James H.

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Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma von Porter, Rebecca L., Magnus, Neelima K. C., Thapar, Vishal, Morris, Robert, Szabolcs, Annamaria, Neyaz, Azfar, Kulkarni, Anupriya S., Tai, Eric, Chougule, Abhijit, Hillis, Alessandra, Golczer, Gabriel, Guo, Hongshan, Yamada, Teppei, Kurokawa, Tomohiro, Yashaswini, Chittampalli, Ligorio, Matteo, Vo, Kevin D., Nieman, Linda, Liss, Andrew S., Deshpande, Vikram, Lawrence, Michael S., Maheswaran, Shyamala, Castillo, Carlos Fernandez-Del, Hong, Theodore S., Ryan, David P., O’Dwyer, Peter J., Drebin, Jeffrey A., Ferrone, Cristina R., Haber, Daniel A., Ting, David T.

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A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma von BEATTY, Gregory L, TORIGIAN, Drew A, O'DWYER, Peter J, GABRIELA CHIOREAN, E, SABOURY, Babak, BROTHERS, Alex, ALAVI, Abass, TROXEL, Andrea B, WEIJING SUN, TEITELBAUM, Ursina R, VONDERHEIDE, Robert H

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Precision Medicine Clinical Trials: A Conversation Between Peter O'Dwyer and Lale Kostakoglu von O'Dwyer, Peter J, Kostakoglu, Lale

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Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W von Chae, Young K, Hong, Fangxin, Vaklavas, Christos, Cheng, Heather H, Hammerman, Peter, Mitchell, Edith P, Zwiebel, James A, Ivy, S Percy, Gray, Robert J, Li, Shuli, McShane, Lisa M, Rubinstein, Larry V, Patton, David, Williams, P Mickey, Hamilton, Stanley R, Mansfield, Aaron, Conley, Barbara A, Arteaga, Carlos L, Harris, Lyndsay N, O'Dwyer, Peter J, Chen, Alice P, Flaherty, Keith T

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Open-label, Phase I Study of Nivolumab Combined with nab -Paclitaxel Plus Gemcitabine in Advanced Pancreatic Cancer von Wainberg, Zev A, Hochster, Howard S, Kim, Edward J, George, Ben, Kaylan, Aparna, Chiorean, E Gabriela, Waterhouse, David M, Guiterrez, Martin, Parikh, Aparna, Jain, Rishi, Carrizosa, Daniel Ricardo, Soliman, Hatem H, Lila, Thomas, Reiss, David J, Pierce, Daniel W, Bhore, Rafia, Banerjee, Sibabrata, Lyons, Larry, Louis, Chrystal U, Ong, Teng Jin, O'Dwyer, Peter J

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Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients von Sausen, Mark, Phallen, Jillian, Adleff, Vilmos, Jones, Siân, Leary, Rebecca J., Barrett, Michael T., Anagnostou, Valsamo, Parpart-Li, Sonya, Murphy, Derek, Kay Li, Qing, Hruban, Carolyn A., Scharpf, Rob, White, James R., O’Dwyer, Peter J., Allen, Peter J., Eshleman, James R., Thompson, Craig B., Klimstra, David S., Linehan, David C., Maitra, Anirban, Hruban, Ralph H., Diaz, Luis A., Von Hoff, Daniel D., Johansen, Julia S., Drebin, Jeffrey A., Velculescu, Victor E.

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Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors von Piha-Paul, Sarina A, Hann, Christine L, French, Christopher A, Cousin, Sophie, Braña, Irene, Cassier, Phillippe A, Moreno, Victor, de Bono, Johann S, Harward, Sara Duckworth, Ferron-Brady, Geraldine, Barbash, Olena, Wyce, Anastasia, Wu, Yuehui, Horner, Thierry, Annan, Meg, Parr, Nigel J, Prinjha, Rabinder K, Carpenter, Christopher L, Hilton, John, Hong, David S, Haas, Naomi B, Markowski, Mark C, Dhar, Arindam, O'Dwyer, Peter J, Shapiro, Geoffrey I

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Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy von SELVAKUMARAN, Muthu, AMARAVADI, Ravi K, VASILEVSKAYA, Irina A, O'DWYER, Peter J

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma von Flaherty, Keith T, Puzanov, Igor, Kim, Kevin B, Ribas, Antoni, McArthur, Grant A, Sosman, Jeffrey A, O'Dwyer, Peter J, Lee, Richard J, Grippo, Joseph F, Nolop, Keith, Chapman, Paul B

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Early treatment-related neutropenia predicts response to palbociclib von McAndrew, Nicholas P., Dickson, Mark A., Clark, Amy S., Troxel, Andrea B., O’Hara, Mark H., Colameco, Christopher, Gallager, Maryann, Gramlich, Kristi, Zafman, Kelly, Vaughn, David, Schwartz, Gary K., O’Dwyer, Peter J., DeMichele, Angela

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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme von Rosenfeld, Myrna R, Ye, Xiaobu, Supko, Jeffrey G, Desideri, Serena, Grossman, Stuart A, Brem, Steven, Mikkelson, Tom, Wang, Daniel, Chang, Yunyoung C, Hu, Janice, McAfee, Quentin, Fisher, Joy, Troxel, Andrea B, Piao, Shengfu, Heitjan, Daniel F, Tan, Kay-See, Pontiggia, Laura, O'Dwyer, Peter J, Davis, Lisa E, Amaravadi, Ravi K

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Nivolumab Is Effective in Mismatch Repair-Deficient Noncolorectal Cancers: Results From Arm Z1D-A Subprotocol of the NCI-MATCH (EAY131) Study von Azad, Nilofer S, Gray, Robert J, Overman, Michael J, Schoenfeld, Jonathan D, Mitchell, Edith P, Zwiebel, James A, Sharon, Elad, Streicher, Howard, Li, Shuli, McShane, Lisa M, Rubinstein, Larry, Patton, David R, Williams, P Mickey, Coffey, Brent, Hamilton, Stanley R, Bahary, Nathan, Suga, J Marie, Hatoum, Hassan, Abrams, Jeffrey S, Conley, Barbara A, Arteaga, Carlos L, Harris, Lyndsay, O'Dwyer, Peter J, Chen, Alice P, Flaherty, Keith T

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