DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats von Brocks, David, Schmidt, Christopher R, Daskalakis, Michael, Jang, Hyo Sik, Shah, Nakul M, Li, Daofeng, Li, Jing, Zhang, Bo, Hou, Yiran, Laudato, Sara, Lipka, Daniel B, Schott, Johanna, Bierhoff, Holger, Assenov, Yassen, Helf, Monika, Ressnerova, Alzbeta, Islam, Md Saiful, Lindroth, Anders M, Haas, Simon, Essers, Marieke, Imbusch, Charles D, Brors, Benedikt, Oehme, Ina, Witt, Olaf, Lübbert, Michael, Mallm, Jan-Philipp, Rippe, Karsten, Will, Rainer, Weichenhan, Dieter, Stoecklin, Georg, Gerhäuser, Clarissa, Oakes, Christopher C, Wang, Ting, Plass, Christoph

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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia von Oakes, Christopher C, Seifert, Marc, Assenov, Yassen, Gu, Lei, Przekopowitz, Martina, Ruppert, Amy S, Wang, Qi, Imbusch, Charles D, Serva, Andrius, Koser, Sandra D, Brocks, David, Lipka, Daniel B, Bogatyrova, Olga, Weichenhan, Dieter, Brors, Benedikt, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Zapatka, Marc, Lichter, Peter, Döhner, Hartmut, Küppers, Ralf, Zenz, Thorsten, Stilgenbauer, Stephan, Byrd, John C, Plass, Christoph

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Insight into origins, mechanisms, and utility of DNA methylation in B-cell malignancies von Oakes, Christopher C., Martin-Subero, Jose I.

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Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy von Dalton, Tanner, Doubrovina, Ekaterina, Pankov, Dmitry, Reynolds, Raymond, Scholze, Hanna, Selvakumar, Annamalai, Vizconde, Teresa, Savalia, Bhumesh, Dyomin, Vadim, Weigel, Christoph, Oakes, Christopher C., Alonso, Alicia, Elemento, Olivier, Pan, Heng, Phillip, Jude M., O'Reilly, Richard J., Gewurz, Benjamin E., Cesarman, Ethel, Giulino-Roth, Lisa

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Single-cell analysis based dissection of clonality in myelofibrosis von Mylonas, Elena, Yoshida, Kenichi, Frick, Mareike, Hoyer, Kaja, Christen, Friederike, Kaeda, Jaspal, Obenaus, Matthias, Noerenberg, Daniel, Hennch, Cornelius, Chan, Willy, Ochi, Yotaro, Shiraishi, Yuichi, Shiozawa, Yusuke, Zenz, Thorsten, Oakes, Christopher C., Sawitzki, Birgit, Schwarz, Michaela, Bullinger, Lars, le Coutre, Philipp, Rose-Zerilli, Matthew J. J., Ogawa, Seishi, Damm, Frederik

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Charting the dynamic epigenome during B-cell development von Martin-Subero, Jose I., Oakes, Christopher C.

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Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A von Arab, Khelifa, Park, Yoon Jung, Lindroth, Anders M., Schäfer, Andrea, Oakes, Christopher, Weichenhan, Dieter, Lukanova, Annekatrin, Lundin, Eva, Risch, Angela, Meister, Michael, Dienemann, Hendrik, Dyckhoff, Gerhard, Herold-Mende, Christel, Grummt, Ingrid, Niehrs, Christof, Plass, Christoph

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Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations von Durham, Benjamin H., Getta, Bartlomiej, Dietrich, Sascha, Taylor, Justin, Won, Helen, Bogenberger, James M., Scott, Sasinya, Kim, Eunhee, Chung, Young Rock, Chung, Stephen S., Hüllein, Jennifer, Walther, Tatjana, Wang, Lu, Lu, Sydney X., Oakes, Christopher C., Tibes, Raoul, Haferlach, Torsten, Taylor, Barry S., Tallman, Martin S., Berger, Michael F., Park, Jae H., Zenz, Thorsten, Abdel-Wahab, Omar

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Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females von McGraw, Serge, Oakes, Christopher C, Martel, Josée, Cirio, M Cecilia, de Zeeuw, Pauline, Mak, Winifred, Plass, Christoph, Bartolomei, Marisa S, Chaillet, J Richard, Trasler, Jacquetta M

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Effects of epigenetic therapy on natural killer cell function and development in hematologic malignancy von Lordo, Matthew R, Stiff, Andrew R, Oakes, Christopher C, Mundy-Bosse, Bethany L

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Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia von Oakes, Christopher C, Claus, Rainer, Gu, Lei, Assenov, Yassen, Hüllein, Jennifer, Zucknick, Manuela, Bieg, Matthias, Brocks, David, Bogatyrova, Olga, Schmidt, Christopher R, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Lichter, Peter, Döhner, Hartmut, Stilgenbauer, Stephan, Byrd, John C, Zenz, Thorsten, Plass, Christoph

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High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells von Oppermann, Sina, Ylanko, Jarkko, Shi, Yonghong, Hariharan, Santosh, Oakes, Christopher C., Brauer, Patrick M., Zúñiga-Pflücker, Juan C., Leber, Brian, Spaner, David E., Andrews, David W.

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Effect of Malaria Infection on Epstein-Barr Virus Persistence in Kenyan Children von Samayoa-Reyes, Gabriela, Weigel, Christoph, Koech, Emmily, Waomba, Kevin, Jackson, Conner, Onditi, Ian A, Sabourin, Katherine R, Kenney, Shannon, Baiocchi, Robert A, Oakes, Christopher C, Ogolla, Sidney, Rochford, Rosemary

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Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia von Lütge, Almut, Lu, Junyan, Hüllein, Jennifer, Walther, Tatjana, Sellner, Leopold, Wu, Bian, Rosenquist, Richard, Oakes, Christopher C, Dietrich, Sascha, Huber, Wolfgang, Zenz, Thorsten

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DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia von Giacopelli, Brian, Wang, Min, Cleary, Ada, Wu, Yue-Zhong, Schultz, Anna Reister, Schmutz, Maximilian, Blachly, James S, Eisfeld, Ann-Kathrin, Mundy-Bosse, Bethany, Vosberg, Sebastian, Greif, Philipp A, Claus, Rainer, Bullinger, Lars, Garzon, Ramiro, Coombes, Kevin R, Bloomfield, Clara D, Druker, Brian J, Tyner, Jeffrey W, Byrd, John C, Oakes, Christopher C

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Outcome prediction by the 2022 European LeukemiaNet genetic-risk classification for adults with acute myeloid leukemia: an Alliance study von Mrózek, Krzysztof, Kohlschmidt, Jessica, Blachly, James S., Nicolet, Deedra, Carroll, Andrew J., Archer, Kellie J., Mims, Alice S., Larkin, Karilyn T., Orwick, Shelley, Oakes, Christopher C., Kolitz, Jonathan E., Powell, Bayard L., Blum, William G., Marcucci, Guido, Baer, Maria R., Uy, Geoffrey L., Stock, Wendy, Byrd, John C., Eisfeld, Ann-Kathrin

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BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence von Gu, Lei, Frommel, Sandra C, Oakes, Christopher C, Simon, Ronald, Grupp, Katharina, Gerig, Cristina Y, Bär, Dominik, Robinson, Mark D, Baer, Constance, Weiss, Melanie, Gu, Zuguang, Schapira, Matthieu, Kuner, Ruprecht, Sültmann, Holger, Provenzano, Maurizio, Yaspo, Marie-Laure, Brors, Benedikt, Korbel, Jan, Schlomm, Thorsten, Sauter, Guido, Eils, Roland, Plass, Christoph, Santoro, Raffaella

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Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint von Masle-Farquhar, Etienne, Peters, Timothy J., Miosge, Lisa A., Parish, Ian A., Weigel, Christoph, Oakes, Christopher C., Reed, Joanne H., Goodnow, Christopher C.

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Telomere length and DNA methylation epitype both provide independent prognostic information in CLL patients; data from the UK CLL4, ARCTIC and ADMIRE clinical trials von Carr, Louise, Norris, Kevin, Parker, Helen, Nilsson-Takeuchi, Anna, Bryant, Dean, Amarasinghe, Harindra, Kadalayil, Latha, Else, Monica, Pettitt, Andrew, Hillmen, Peter, Schuh, Anna, Walewska, Renata, Baird, Duncan M, Oscier, David G, Oakes, Christopher C, Gibson, Jane, Pepper, Chris, Strefford, Jonathan C

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Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer von Brocks, David, Assenov, Yassen, Minner, Sarah, Bogatyrova, Olga, Simon, Ronald, Koop, Christina, Oakes, Christopher, Zucknick, Manuela, Lipka, Daniel Bernhard, Weischenfeldt, Joachim, Feuerbach, Lars, Cowper-Sal·lari, Richard, Lupien, Mathieu, Brors, Benedikt, Korbel, Jan, Schlomm, Thorsten, Tanay, Amos, Sauter, Guido, Gerhäuser, Clarissa, Plass, Christoph

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