CTC-5: A novel digital pathology approach to characterise circulating tumour cell biodiversity von Ffrench, B., Kashdan, E., Huang, Y., Spillane, C.D., Cocchiglia, S., Charmsaz, S., Varešlija, D., O'Brien, C., Scholz, D., Martin, C., Gallagher, M., Brooks, D.A., Brooks, R.D., Selemidis, S., Gleeson, N., AbuSaadeh, F., O'Riain, C., Kamran, W., Flavin, R., Young, L., O'Toole, S.A., O'Leary, J.J.

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ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer von van Geldermalsen, M, Wang, Q, Nagarajah, R, Marshall, A D, Thoeng, A, Gao, D, Ritchie, W, Feng, Y, Bailey, C G, Deng, N, Harvey, K, Beith, J M, Selinger, C I, O'Toole, S A, Rasko, J E J, Holst, J

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659 Hedgehog Pathway Expression in a Mouse Model of Liver Cell Dysplasia von Grzelak, C.A, Sigglekow, N.D, Warner, F.J, Patkunanathan, B, O'Toole, S.A, Kench, J.G, Shackel, N.A, McCaughan, G.W

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Potential predictors of chemotherapy response in ovarian cancer—How do we define chemosensitivity? von O'Toole, S.A, Sheppard, B.L, Laios, A, O'Leary, J.J, McGuinness, E.P.J, D'Arcy, T, Bonnar, J

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Extended thromboprophylaxis post gynaecological cancer surgery; the effect of weight adjusted and fixed dose LMWH (Tinzaparin) von Abu Saadeh, F., Marchocki, Z., O'Toole, S.A., Ibrahim, N., Gleeson, N., Norris, L.A.

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c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer von Nair, R, Roden, D L, Teo, W S, McFarland, A, Junankar, S, Ye, S, Nguyen, A, Yang, J, Nikolic, I, Hui, M, Morey, A, Shah, J, Pfefferle, A D, Usary, J, Selinger, C, Baker, L A, Armstrong, N, Cowley, M J, Naylor, M J, Ormandy, C J, Lakhani, S R, Herschkowitz, J I, Perou, C M, Kaplan, W, O'Toole, S A, Swarbrick, A

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OC-12 - Peri operative venous thromboembolism prophylaxis in gynaecological cancer patients. A survey of current practice von Petch, S, Norris, L.A, O’Toole, S.A, Gleeson, N, Saadeh, F. Abu

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Development and validation of a risk model for prediction of venous thromboembolism in gynaecological cancer patients von Norris, L.A., Abu Saadeh, F., Ward, M., O'Toole, S.A., Machocki, Z., Ibrahim, N., Gleeson, N.

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297P SP142 immunohistochemistry (IHC) PD-L1 inter- and intra-pathologist agreement in triple negative breast carcinoma (TNBC) von Pang, J-M., Castles, B., Byrne, D.J., Button, P., Lakhani, S., Sivasubramaniam, V., Cooper, W., Armes, J., Millar, E., Raymond, W., Roberts-Thomson, S., Kumar, B., Burr, M.L., Selinger, C., Harvey, K., Chan, C., Beith, J., O'Toole, S.A., Fox, S.B.

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PO-24 - Determinants of thrombin generation in gynaecological malignancies von Norris, L.A, Martin, F.A, O’Toole, S.A, Saadeh, F. Abu, Gleeson, N

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Genome‐wide analysis of deoxyribonucleic acid in endometrial cancer using comparative genomic hybridization microarrays von O’TOOLE, S.A., DUNN, E., SHEPPARD, B.L., KLOCKER, H., BEKTIC, J., SMYTH, P., MARTIN, C., SHEILS, O., O’LEARY, J.J.

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PO-14 - Tumour expression of coagulation proteases of the aPC pathway – a role in the pathogenesis of gynaecological cancers? von Martin, F, Long, J.C, O’Toole, S.A, O’Leary, J.J, Abu Saadeh, F, Gleeson, N, Norris, L.A

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Using the epigenome to understand and better classify phyllodes tumours von O'Toole, S.A., Pidsley, R., Harvey, K., Karim, R., Lee, C.S., Chan, B., Stirzaker, C.

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Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome von Millar, E K A, Dean, J L, McNeil, C M, O'Toole, S A, Henshall, S M, Tran, T, Lin, J, Quong, A, Comstock, C E S, Witkiewicz, A, Musgrove, E A, Rui, H, LeMarchand, L, Setiawan, V W, Haiman, C A, Knudsen, K E, Sutherland, R L, Knudsen, E S

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Targeted next generation sequencing in FFPE samples of NSCLC von Cooper, W.A., Kraitsek, S., Selinger, C.I., Tran, T., Kohonen-Corish, M., O'Toole, S.A., Yu, B.

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Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsi... von Roberts, C G, Millar, E K A, O'Toole, S A, McNeil, C M, Lehrbach, G M, Pinese, M, Tobelmann, P, McCloy, R A, Musgrove, E A, Sutherland, R L, Butt, A J

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5008 ORAL miRNA signatures in recurrent ovarian cancer von Laios, A, O'Toole, S.A, Sheppard, B, Gleeson, N.C, D'Arcy, T, McGuinness, E.P.J, Flavin, R, Ring, M, Sheils, O, O'Leary, J.J

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PO-03 Is extended thromboprophylaxis required for all gynaecological cancer patients post-surgery? von Abu Saadeh, F., Marchocki, Z., O’Toole, S.A., Gleeson, N., Kashan, A., Norris, L.A.

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Fibrinogen, D-Dimers and thrombin generation assays as predictors of the risk of recurrent VTE in patients with gynaecological malignancies von Marchocki, Z., Gleeson, N., Abu Saadeh, F., Ward, M.P., O’Toole, S.A., Norris, L.A.

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Patients experience and compliance with extended LMWH prophylaxis post-surgery for gynaecological cancer von Marchocki, Z., Norris, L.N., O’Toole, S.A., Gleeson, N., Abu Saadeh, F.

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