Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells von Barron, Luke, Dooms, Hans, Hoyer, Katrina K, Kuswanto, Wilson, Hofmann, Jerry, O'Gorman, William E, Abbas, Abul K

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Mammalian Target of Rapamycin Controls Dendritic Cell Development Downstream of Flt3 Ligand Signaling von Sathaliyawala, Taheri, O'Gorman, William E., Greter, Melanie, Bogunovic, Milena, Konjufca, Vjollca, Hou, Z. Esther, Nolan, Garry P., Miller, Mark J., Merad, Miriam, Reizis, Boris

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Quantitative Comparison of Conventional and t-SNE-guided Gating Analyses von Toghi Eshghi, Shadi, Au-Yeung, Amelia, Takahashi, Chikara, Bolen, Christopher R, Nyachienga, Maclean N, Lear, Sean P, Green, Cherie, Mathews, W Rodney, O'Gorman, William E

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Mass cytometry panel optimization through the designed distribution of signal interference von Takahashi, Chikara, Au‐Yeung, Amelia, Fuh, Franklin, Ramirez‐Montagut, Teresa, Bolen, Chris, Mathews, William, O'Gorman, William E.

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Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus von O'Gorman, William E., PhD, Hsieh, Elena W.Y., MD, Savig, Erica S., BA, Gherardini, Pier Federico, PhD, Hernandez, Joseph D., MD, PhD, Hansmann, Leo, PhD, Balboni, Imelda M., MD, PhD, Utz, Paul J., MD, PhD, Bendall, Sean C., PhD, Fantl, Wendy J., PhD, Lewis, David B., MD, Nolan, Garry P., PhD, Davis, Mark M., PhD

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Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade von Banchereau, Romain, Chitre, Avantika S., Scherl, Alexis, Wu, Thomas D., Patil, Namrata S., de Almeida, Patricia, Kadel, III, Edward E., Madireddi, Shravan, Au-Yeung, Amelia, Takahashi, Chikara, Chen, Ying-Jiun, Modrusan, Zora, McBride, Jacqueline, Nersesian, Rhea, El-Gabry, Ehab A., Robida, Mark D., Hung, Jeffrey C., Kowanetz, Marcin, Zou, Wei, McCleland, Mark, Caplazi, Patrick, Eshgi, Shadi Toghi, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Mathews, W. Rodney, Powles, Thomas, Mariathasan, Sanjeev, Grogan, Jane, O'Gorman, William E

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Visualization of Mass Cytometry Signal Background to Enable Optimal Core Panel Customization and Signal Threshold Gating von Au-Yeung, Amelia, Takahashi, Chikara, Mathews, W. Rodney, O’Gorman, William E.

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The Split Virus Influenza Vaccine rapidly activates immune cells through Fcγ receptors von O’Gorman, William E, Huang, Huang, Wei, Yu-Ling, Davis, Kara L, Leipold, Michael D, Bendall, Sean C, Kidd, Brian A, Dekker, Cornelia L, Maecker, Holden T, Chien, Yueh-Hsiu, Davis, Mark M

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Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses von Banta, Karl L., Xu, Xiaozheng, Chitre, Avantika S., Au-Yeung, Amelia, Takahashi, Chikara, O’Gorman, William E., Wu, Thomas D., Mittman, Stephanie, Cubas, Rafael, Comps-Agrar, Laetitia, Fulzele, Amit, Bennett, Eric J., Grogan, Jane L., Hui, Enfu, Chiang, Eugene Y., Mellman, Ira

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Duration of antigen receptor signaling determines T-cell tolerance or activation von Katzman, Shoshana D., O’Gorman, William E., Villarino, Alejandro V., Gallo, Eugenio, Friedman, Rachel S., Krummel, Matthew F., Nolan, Garry P., Abbas, Abul K., Weiss, Arthur

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Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer von Patil, Namrata S., Nabet, Barzin Y., Müller, Sören, Koeppen, Hartmut, Zou, Wei, Giltnane, Jennifer, Au-Yeung, Amelia, Srivats, Shyam, Cheng, Jason H., Takahashi, Chikara, de Almeida, Patricia E., Chitre, Avantika S., Grogan, Jane L., Rangell, Linda, Jayakar, Sangeeta, Peterson, Maureen, Hsia, Allison W., O’Gorman, William E., Ballinger, Marcus, Banchereau, Romain, Shames, David S.

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Peripheral T cell expansion predicts tumour infiltration and clinical response von Wu, Thomas D., Madireddi, Shravan, de Almeida, Patricia E., Banchereau, Romain, Chen, Ying-Jiun J., Chitre, Avantika S., Chiang, Eugene Y., Iftikhar, Hina, O’Gorman, William E., Au-Yeung, Amelia, Takahashi, Chikara, Goldstein, Leonard D., Poon, Chungkee, Keerthivasan, Shilpa, de Almeida Nagata, Denise E., Du, Xiangnan, Lee, Hyang-Mi, Banta, Karl L., Mariathasan, Sanjeev, Das Thakur, Meghna, Huseni, Mahrukh A., Ballinger, Marcus, Estay, Ivette, Caplazi, Patrick, Modrusan, Zora, Delamarre, Lélia, Mellman, Ira, Bourgon, Richard, Grogan, Jane L.

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Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes von Rahim, Maha K., Okholm, Trine Line H., Jones, Kyle B., McCarthy, Elizabeth E., Liu, Candace C., Yee, Jacqueline L., Tamaki, Stanley J., Marquez, Diana M., Tenvooren, Iliana, Wai, Katherine, Cheung, Alexander, Davidson, Brittany R., Johri, Vrinda, Samad, Bushra, O’Gorman, William E., Krummel, Matthew F., van Zante, Annemieke, Combes, Alexis J., Angelo, Michael, Fong, Lawrence, Algazi, Alain P., Ha, Patrick, Spitzer, Matthew H.

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The potential functions of primary microRNAs in target recognition and repression von Trujillo, Robin Deis, Yue, Si-Biao, Tang, Yujie, O'Gorman, William E, Chen, Chang-Zheng

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Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry von Baxter, Ryan M, Kong, Daniel S, Garcia-Perez, Josselyn E, O'Gorman, William E, Hsieh, Elena W Y

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Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment von Fehlings, Michael, Jhunjhunwala, Suchit, Kowanetz, Marcin, O’Gorman, William E., Hegde, Priti S., Sumatoh, Hermi, Lee, Boon Heng, Nardin, Alessandra, Becht, Etienne, Flynn, Susan, Ballinger, Marcus, Newell, Evan W., Yadav, Mahesh

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Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B von Daemen, Anneleen, Udyavar, Akshata R., Sandmann, Thomas, Li, Congfen, Bosch, Linda J. W., O'Gorman, William, Li, Yijin, Au-Yeung, Amelia, Takahashi, Chikara, Kabbarah, Omar, Bourgon, Richard, Hegde, Priti, Bais, Carlos, Das Thakur, Meghna

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High Dimensional Single-Cell Mass Cytometry Demonstrates Conserved Human Toll-Like-Receptor Activation Signatures von Hsieh, Elena, Dr, O'Gorman, William, Dr, Savig, Erica, Ms, Gherardini, Pier Federico, Dr, Davis, Mark, Prof, Nolan, Garry, Prof

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Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP von Burbach, Brandon J, Srivastava, Rupa, Medeiros, Ricardo B, O'Gorman, William E, Peterson, Erik J, Shimizu, Yoji

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Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963 von Thorne, Steve H, Hwang, Tae-Ho H, O'Gorman, William E, Bartlett, David L, Sei, Shizuko, Kanji, Femina, Brown, Christopher, Werier, Joel, Cho, Jin-Han, Lee, Dong-Ewon, Wang, Yaohe, Bell, John, Kirn, David H

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