Distinguishing genetic correlation from causation across 52 diseases and complex traits von O’Connor, Luke J., Price, Alkes L.

Volltext

The distribution of common-variant effect sizes von O’Connor, Luke J.

Volltext

Quantifying genetic effects on disease mediated by assayed gene expression levels von Yao, Douglas W., O’Connor, Luke J., Price, Alkes L., Gusev, Alexander

Volltext

Extreme Polygenicity of Complex Traits Is Explained by Negative Selection von O'Connor, Luke J., Schoech, Armin P., Hormozdiari, Farhad, Gazal, Steven, Patterson, Nick, Price, Alkes L.

Volltext

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank von Zhu, Zhaozhong, Guo, Yanjun, Shi, Huwenbo, Liu, Cong-Lin, Panganiban, Ronald Allan, Chung, Wonil, O'Connor, Luke J., Himes, Blanca E., Gazal, Steven, Hasegawa, Kohei, Camargo, Carlos A., Qi, Lu, Moffatt, Miriam F., Hu, Frank B., Lu, Quan, Cookson, William O.C., Liang, Liming

Volltext

Partitioning gene-mediated disease heritability without eQTLs von Weiner, Daniel J., Gazal, Steven, Robinson, Elise B., O’Connor, Luke J.

Volltext

HAPNEST: efficient, large-scale generation and evaluation of synthetic datasets for genotypes and phenotypes von Wharrie, Sophie, Yang, Zhiyu, Raj, Vishnu, Monti, Remo, Gupta, Rahul, Wang, Ying, Martin, Alicia, O’Connor, Luke J, Kaski, Samuel, Marttinen, Pekka, Palamara, Pier Francesco, Lippert, Christoph, Ganna, Andrea

Volltext

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection von Schoech, Armin P., Jordan, Daniel M., Loh, Po-Ru, Gazal, Steven, O’Connor, Luke J., Balick, Daniel J., Palamara, Pier F., Finucane, Hilary K., Sunyaev, Shamil R., Price, Alkes L.

Volltext

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity von Gazal, Steven, Weissbrod, Omer, Hormozdiari, Farhad, Dey, Kushal K., Nasser, Joseph, Jagadeesh, Karthik A., Weiner, Daniel J., Shi, Huwenbo, Fulco, Charles P., O’Connor, Luke J., Pasaniuc, Bogdan, Engreitz, Jesse M., Price, Alkes L.

Volltext

Polygenic architecture of rare coding variation across 394,783 exomes von Weiner, Daniel J., Nadig, Ajay, Jagadeesh, Karthik A., Dey, Kushal K., Neale, Benjamin M., Robinson, Elise B., Karczewski, Konrad J., O’Connor, Luke J.

Volltext

Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies von Salehi Nowbandegani, Pouria, Wohns, Anthony Wilder, Ballard, Jenna L., Lander, Eric S., Bloemendal, Alex, Neale, Benjamin M., O’Connor, Luke J.

Volltext

Author Correction: Distinguishing genetic correlation from causation across 52 diseases and complex traits von O’Connor, Luke J., Price, Alkes L.

Volltext

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p von Weiner, Daniel J., Ling, Emi, Erdin, Serkan, Tai, Derek J. C., Yadav, Rachita, Grove, Jakob, Fu, Jack M., Nadig, Ajay, Carey, Caitlin E., Baya, Nikolas, Bybjerg-Grauholm, Jonas, Berretta, Sabina, Macosko, Evan Z., Sebat, Jonathan, O’Connor, Luke J., Hougaard, David M., Børglum, Anders D., Talkowski, Michael E., McCarroll, Steven A., Robinson, Elise B.

Volltext

38. COMMON AND RARE GENETIC RISK FACTORS FOR SCHIZOPHRENIA AT CHROMOSOME 22Q INDUCE CONVERGENT, DISPERSED CHANGES IN GENE EXPRESSION von Nadig, Ajay, Tegtmeyer, Matthew, Weiner, Daniel J., Ling, Emi, Gordon, Aaron, O'Connor, Luke J., Aryee, Martin J., Bearden, Carrie E., Geschwind, Daniel, McCarroll, Steve A., Nehme, Ralda, Robinson, Elise B.

Volltext

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p von Weiner, Daniel J, Ling, Emi, Erdin, Serkan, Tai, Derek J.C, Yadav, Rachita, Grove, Jakob, Fu, Jack M, Nadig, Ajay, Carey, Caitlin E, Baya, Nikolas, Bybjerg Grauholm, Jonas, iPSYCH Consortium, PGC ASD, PGC ADHD, Berretta, Sabina, Macosko, Evan Z, Sebat, Jonathan, O'Connor, Luke J, Hougaard, David M, Børglum, Anders D, Talkowski, Michael E, McCarroll, Steven A, Robinson, Elise B

Volltext

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p von Weiner, Daniel J., Ling, Emi, Erdin, Serkan, Tai, Derek J. C., Yadav, Rachita, Grove, Jakob, Fu, Jack M., Nadig, Ajay, Carey, Caitlin E., Baya, Nikolas, Bybjerg-Grauholm, Jonas, Mortensen, Preben B., Werge, Thomas, Demontis, Ditte, Mors, Ole, Nordentoft, Merete, Als, Thomas D., Baekvad-Hansen, Marie, Rosengren, Anders, Havdahl, Alexandra Karoline Saasen, Hedemand, Anne, Palotie, Aarno, Chakravarti, Aravinda, Sulovari, Arvis, Starnawska, Anna, Thiruvahindrapuram, Bhooma, de Leeuw, Christiaan, Carey, Caitlin, Ladd-Acosta, Christine, van der Merwe, Celia, Devlin, Bernie, Cook, Edwin H., Eichler, Evan, Corfield, Elizabeth Claire, Dieleman, Gwen, Schellenberg, Gerard, Hakonarson, Hakon, Dziobek, Isabel, Vorstman, Jacob, Girault, Jessica, Sutcliffe, James S., Duan, Jinjie, Nurnberger, John, Hallmayer, Joachim, Piven, Joseph, Weiss, Lauren, Davis, Lea, Janecka, Magdalena, Mattheisen, Manuel, State, Matthew W., Daly, Mark, Uddin, Mohammed, Andreassen, Ole, Szatmari, Peter, Lee, Phil Hyoun, Anney, Richard, Ripke, Stephan, Satterstrom, Kyle, Santangelo, Susan, Kuo, Susan, van Elst, Ludger Tebartz, Rolland, Thomas, Bougeron, Thomas, Polderman, Tinca, Turner, Tychele, Underwood, Jack, Manikandan, Veera, Pillalamarri, Vamsee, Warrier, Varun, Philipsen, Alexandra, Reif, Andreas, Hinney, Anke, Cormand, Bru, Bau, Claiton H. D., Rovaris, Diego Luiz, Sonuga-Barke, Edmund, Grevet, Eugenio Horacio, Salum, Giovanni, Larsson, Henrik Bo W., Buitelaar, Jan, McGough, James, Kuntsi, Jonna, Elia, Josephine, Lesch, Klaus-Peter, Klein, Marieke, Bellgrove, Mark, Tesli, Martin Steen, Leung, Patrick W. L., Pan, Pedro M., Dalsgaard, Søren, Faraone, Stephen, Reichborn-Kjennerud, Ted, Banaschewski, Tobias, Hawi, Ziarih, Berretta, Sabina, Macosko, Evan Z., Hougaard, David M., Talkowski, Michael E., McCarroll, Steven A., Robinson, Elise B.

Volltext

Distinguishing correlation from causation using genome-wide association studies von O'Connor, Luke J, Price, Alkes L

Volltext bestellen

Distinguishing correlation from causation using genome-wide association studies von O'Connor, Luke J, Price, Alkes L

Volltext

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels von Tin, Adrienne, Wuttke, Matthias, Qiu, Chengxiang, Gorski, Mathias, Yu, Zhi, Giri, Ayush, Chu, Audrey Y, O'Connor, Luke J, Prins, Bram, Nutile, Teresa, Noce, Damia, Cocca, Massimiliano, Amin, Najaf, Bansal, Nisha, Baptista, Daniela, Bergmann, Sven, Boerwinkle, Eric, Bottinger, Erwin P, Boutin, Thibaud S, Brumat, Marco, Carroll, Robert J, Chambers, John C, Corre, Tanguy, Felicita, Sala Cinzia, de Vries, Aiko PJ, Delgado, Graciela, Demirkan, Ayşe, Devuyst, Olivier, Eckardt, Kai-Uwe, Endlich, Karlhans, Gasparini, Paolo, Giedraitis, Vilmantas, Haller, Toomas, Harris, Tamara B, Hayward, Caroline, Hicks, Andrew A, Hofer, Edith, Lewis, Raychel M, Ingelsson, Erik, Jakobsdottir, Johanna, Jonsdottir, Ingileif, Joshi, Peter K, Kamatani, Yoichiro, Kanai, Masahiro, Kerr, Shona M, Koenig, Wolfgang, Kovacs, Peter, La Bianca, Martina, Lehtimäki, Terho, Lifelines Cohort Study, Mahajan, Anubha, Martin, Nicholas G, März, Winfried, Meitinger, Thomas, Metspalu, Andres, V. A. Million Veteran Program, O'Donnell, Christopher J, Wilson, Otis D, Gaziano, J Michael, Mohlke, Karen L, Montgomery, Grant W, Müller-Nurasyid, Martina, Nalls, Mike A, Nauck, Matthias, Nikus, Kjell, Nolte, Ilja M, Olafsson, Isleifur, Padmanabhan, Sandosh, Peters, Annette, Poulain, Tanja, Preuss, Michael H, Rabelink, Ton J, Raffield, Laura M, Rice, Kenneth M, Robino, Antonietta, Rueedi, Rico, Salvi, Erika, Schmidt, Reinhold, Shaffer, Christian M, Teren, Andrej, Thiery, Joachim, Thorsteinsdottir, Unnur, Toniolo, Daniela, Tönjes, Anke, Vaccargiu, Simona, Verweij, Niek, Waeber, Gerard, Waldenberger, Melanie, Wild, Sarah H, Yang, Qiong, Zhang, Weihua, Zonderman, Alan B, Wilson, James G, Parsa, Afshin, Böger, Carsten A, Okada, Yukinori, Edwards, Todd L, Pattaro, Cristian, Vitart, Veronique, Köttgen, Anna

Volltext bestellen

Method for inter-enterprise role-based authorization von Ludwig, Heiko H, O'Connor, Luke J

Volltext bestellen