INITIAL RESULTS FROM THE CASCADE-FH REGISTRY: CASCADE SCREENING FOR AWARENESS AND DETECTION OF FAMILIAL HYPERCHOLESTEROLEMIA von O’Brien, Emily Claire, DeGoma, Emil, Moriarty, Patrick, Linton, MacRae F, Shapiro, Michael, Duell, Bart, Ballantyne, Christie, Neal, William, Ahmad, Zahid, Duffy, Danielle, Hudgins, Lisa, Hemphill, Linda, Underberg, James, Watson, Karol, Gidding, Samuel, Baum, Seth, Dilzell, Kristen, Ross, Joyce, Pickhardt, David, Kindt, Iris, Rader, Daniel, Wilemon, Katherine, Roe, Matthew, Knowles, Joshua

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PROVIDE-HF STUDY RESULTS: PATIENT-REPORTED OUTCOMES INVESTIGATION FOLLOWING INITIATION OF DRUG THERAPY WITH ENTRESTO (SACUBITRIL/VALSARTAN) IN HEART FAILURE von Mentz, Robert John, Xu, Haolin, O'Brien, Emily Claire, Thomas, Laine, Alexy, Tamas, Gupta, Bhanu, Vilaro, Juan, Lala, Anuradha (Anu), Dhingra, Ravi, Briasoulis, Alexandros, Simon, Marc A., Stehlik, Josef, Rodgers, Jo, Dunlay, Shannon, Abshire, Martha, Wells, Quinn, Barringhaus, Kurt G., Eckman, Peter, Lowes, Brian, Espinoza, Johana, Blanco, Rosalia, Shen, Xian, Duffy, Carol, Hernandez, Adrian

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NUISANCE BLEEDING IN ANTICOAGULATED PATIENTS WITH ATRIAL FIBRILLATION: INSIGHTS FROM THE OUTCOMES REGISTRY FOR BETTER INFORMED TREATMENT OF ATRIAL FIBRILLATION (ORBIT-AF) von O'Brien, Emily Claire, Simon, DaJuanicia, Thomas, Laine, Singer, Daniel, Kowey, Peter, Naccarelli, Gerald, Fonarow, Gregg, Reiffel, James A, Ansell, Jack, Go, Alan S, Chan, Paul, Ezekowitz, Michael, Gersh, Bernard, Allen, Larry, Freeman, James, Mahaffey, Kenneth, Piccini, Jonathan, Peterson, Eric, Hylek, Elaine

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Inherent and modifiable risk factors for peripheral venous catheter failure during cancer treatment: a prospective cohort study von Larsen, Emily N., Marsh, Nicole, O’Brien, Catherine, Monteagle, Emily, Friese, Christopher, Rickard, Claire M.

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Review article: the future of microbiome‐based therapeutics von Gulliver, Emily L., Young, Remy B., Chonwerawong, Michelle, D'Adamo, Gemma L., Thomason, Tamblyn, Widdop, James T., Rutten, Emily L., Rossetto Marcelino, Vanessa, Bryant, Robert V., Costello, Samuel P., O'Brien, Claire L., Hold, Georgina L., Giles, Edward M., Forster, Samuel C.

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What are shared and social values of ecosystems? von Kenter, Jasper O., O'Brien, Liz, Hockley, Neal, Ravenscroft, Neil, Fazey, Ioan, Irvine, Katherine N., Reed, Mark S., Christie, Michael, Brady, Emily, Bryce, Rosalind, Church, Andrew, Cooper, Nigel, Davies, Althea, Evely, Anna, Everard, Mark, Fish, Robert, Fisher, Janet A., Jobstvogt, Niels, Molloy, Claire, Orchard-Webb, Johanne, Ranger, Susan, Ryan, Mandy, Watson, Verity, Williams, Susan

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Pregnancy and neonatal outcomes of COVID‐19: coreporting of common outcomes from PAN‐COVID and AAP‐SONPM registries von Barnette, K., Perry, A., Lees, C. C., Nallapeta, Soum, Peers, Beth, Iliodromiti, Stamatina, Armstrong, Maggie, Mutema, Eric, Syson, Jen, Thornton, Danielle, Ajay, Bini, Woodward, Zoe, Mason, Nicky, Moller‐Christensen, Christine, Jaleel, Shazia, Revell, Kirsty, Amin, Allison, Sherris, Leanne, Mansfield, Roshni, Raven, Jamie‐Louise, Sukrutha, Veerareddy, Fayadh, Anam, Kausar, Sameena, Harrington, Andrea, Lear, Emily, Kousar, Rukhsana, Essien, Sandra, Gowans, Sharon, Huson, Coralie, Barker, Katie, Newport, Rachel, Garner, Zoe, Lee, Fidelma, Anderson, Michelle, Everden, Caroline, Jokhi, Roobin, O'Brien, Clare, Bishop, Linda, Heal, Carrie, Jones, Sharon, Cloherty, Karen, Kermack, Alexandra, Liebling, Rachel, Khare, Manjiri, Halawa, Sherry, Narayanan, Sankara, Brain, Jessie, Pandey, Bhavna, Dooks, Emma, Tarft, Hayley, Newman, Tabitha, Thomas, Amy, Woodhead, Amy, Stoddard, Emma, Rhead, Kat, Frankland, Lisa, Home, Marie, Holroyd, Kelly, Sutton‐Cole, Amy, Keeping, Vikki, Kelly‐Baxter, Mary, Upson, Gerry, Creeth, Annabel, Johnson, Sarah, Rand, James, Taylor, Sasha, Edwards, Alex, Grant, Rachael, Truslove, Tracy, Dunham, Tracey, Mathew, Asha, Goodier, Jenny, Jenkins, Elinor, Ambler, Sarah‐Jayne, Pepper, Stacey, Dixon, Caroline, Paulose, Minimol, Alvarez, Mary, Hardy, Rachel, Hodgen, Lesley, Glyn‐Jones, Liz, Pyart, Eleanor, Burnard, Sara, Gill, Many, Harwood, Helen, Parish, Gemma, Hake, Danielle, Maher, Sarah, Watkins, Eve, Lal, Komal, Yelnoorkar, Fiona, Coton, Zoe, Lever, Erin, Watts, Rujnita, Patterson, Molly, Hollands, Heidi, Riddles, Laura, Evans, Melanie, Wood, Diane, Elliott, Kerry

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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK von Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart

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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four random... von Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Feng, Shuo, Marshall, Richard P, Milan, Eveline P, Pollock, Katrina M, Ramasamy, Maheshi N, Robinson, Hannah, Andrade, Claudia Sala, Barker, Debbie, Bates, Louise, Batten, Alexander, Berzenyi, Daniella, Bird, Adam, Blundell, Susannah R., Budd, William, Cabrera Puig, Ingrid, Calvert, Anna, Carvalho, Yasmin de M., Castro, Thais R.Y., Chiplin, Emily, Cifuentes, Liliana, Danos, Zsofia, Dantas, Maria T.D.C., Davies, Sophie, Desai, Amisha, Drake-Brockman, Rachael, Edwards, Mandy, Edwards, Nick J., El Muhanna, Omar M., Ellison-Handley, Branwen, Fedosyuk, Sofiya, Fisher, Richard, Fofie, Hazel, Franco, Marilia M., Fuskova, Michelle, Godwin, Kerry, Gokani, Karishma, Gonçalves, Maria Luisa Freire, Goodall, Jack, Harris-Wright, Tara A., Howell, Nicola, Humphreys, Jonathan, Iyer, Vidyashankara, Jackson, Susan, Jaumdally, Shameem, Jorge, Marianna Rocha, Kellett Wright, Johanna, Kelly, Elizabeth J., Kelly, Dearbhla M., Kidd, Sarah, Larwood, Jessica P.J., Lees, Emily A., Lelliott, Alice, Leung, Stephanie, Manning, Nicola, Mazur, Olga, McGlashan, Joanna, Megson, Clare, Mesquita, Ana Carolina F., Mitton, Celia, Morrison, Hazel, Morselli, Franca, Oliveira, Catarina, Oosthuizen, Angela, Owen, David R.J., Parracho, Helena M. R.T., Perez, Ana Luiza, Perinpanathan, Tanaraj, Perumal, Rubeshan, Plank, Mary, Proud, Pamela C., Rajeswaran, Thurkka, Rees, Byron, Rhead, Sarah, Richards, Alexander, Roberts, Hannah, Robinson, Ryan E., Rudiansyah, Indra, Saunders, Jack E., Screaton, Gavin R., Sorley, Kim, Spencer, Alexandra J., Spoors, Louise, Stein, Ricardo, Strickland, Louise H., Sturdy, Ann, Sutton, Natalina, Taoushanis, Carol, Thomas, Merin, Tinoco, Lygia Accioly, Tomic, Adriana, Truby, Adam, Underwood, Benjamin R., Vichos, Iason, Watkins, Bridget, Wellbelove, Zoe, White, Caroline, Willingham, Silvia

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Acceptance and Commitment Therapy plus usual care for improving quality of life in people with motor neuron disease (COMMEND): a multicentre, parallel, randomised controlled trial... von Gould, Rebecca L, McDermott, Christopher J, Thompson, Benjamin J, Rawlinson, Charlotte V, Bursnall, Matt, Bradburn, Mike, Kumar, Pavithra, Turton, Emily J, White, David A, Serfaty, Marc A, Graham, Christopher D, McCracken, Lance M, Goldstein, Laura H, Al-Chalabi, Ammar, Orrell, Richard W, Williams, Tim, Noad, Rupert, Baker, Idris, Faull, Christina, Lambert, Thomas, Chhetri, Suresh K, Ealing, John, Hanratty, Anthony, Radunovic, Aleksandar, Gunawardana, Nushan, Meadows, Gail, Gorrie, George H, Young, Tracey, Lawrence, Vanessa, Cooper, Cindy, Shaw, Pamela J, Howard, Robert J, Andreou, Penny, Androulaki-Korakaki, Dynameni, Blakeley, Claire, Bridges, Gary, Campbell, Iain, Davenport, Brittany, Dee, Annily, Drewry, Nicola, Flood, John, Fox, Annemieke, Girling, Melissa, Glew, Ruth, Hartley, Nick, Hocking, Sian, Howell, Mark, Keetharuth, Anju, Makin, Selina, Marsh, Jessica, Mayberry, Emily, McDonald, Alexa, McPartland, Roy, Meldrum, Steven, Mobley, Amanda, Murphy, Donnchadh, O'Brien, Marie Claire, Oliver, Mark, Patel, Darshna, Phipps, Emma, Read, Jessica, Roberts, Rhys, Rooney, Natasha, Smith, Carla, Statham, Jo, Thompson, Cara, Varma, Priya, Walker, Anne Marie, Waterhouse, Simon

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Safety and efficacy of midline catheters versus peripheral intravenous catheters: A pilot randomized controlled trial von Marsh, Nicole, Larsen, Emily N., O'Brien, Catherine, Ware, Robert S., Kleidon, Tricia M., Groom, Peter, Hewer, Barbara, Alexandrou, Evan, Flynn, Julie, Woollett, Kaylene, Rickard, Claire M.

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Securing jugular central venous access devices with dressings fixed to a liquid adhesive in an intensive care unit population: a randomised controlled trial von Pearse, India, Corley, Amanda, Larsen, Emily N, Rickard, Claire M, Ware, Robert S, Campbell, Jill, Coyer, Fiona, Alexandrou, Evan, O'Brien, Catherine, Marsh, Nicole

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Comparing the use of midline catheters versus peripherally inserted central catheters for patients requiring peripherally compatible therapies: A pilot randomised controlled trial... von Marsh, Nicole, Larsen, Emily N, O'Brien, Catherine, Groom, Peter, Kleidon, Tricia M, Alexandrou, Evan, Young, Emily, McCarthy, Kate, Rickard, Claire M

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Controlling peripheral intravenous catheter failure by needleless connector design: A pilot randomised controlled trial von Marsh, Nicole, Larsen, Emily, O’Brien, Catherine, Peach, Hannah, Keogh, Samantha, Davies, Karen, Mihala, Gabor, Hewer, Barbara, Booker, Catriona, McCarthy, Alexandra L., Flynn, Julie, Rickard, Claire M.

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Outcomes of the novel Odon Device in indicated operative vaginal birth von Hotton, Emily J., Lenguerrand, Erik, Alvarez, Mary, O’Brien, Stephen, Draycott, Tim J., Crofts, Joanna F., Alvarez, Mary, Arulkumaran, Sabaratnam, Bale, Nichola, Blencowe, Natalie S., Crofts, Joanna F., Draycott, Timothy J., Exell, Lily, Glover, Anne, Hall, Sally, Hotton, Emily J., Lenguerrand, Erik, Lewis-White, Helen, Mallinson, Naomi, Mayer, Michelle, McKeown-Keegan, Sadie, Mola, Glen, O’Brien, Stephen, Pike, Alison, Smith, Iona, Rose, Claire, Villis, Sherrie, Wade, Julia, White, Paul, Winter, Cathy

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The OdonAssist inflatable device for assisted vaginal birth—the ASSIST II study (United Kingdom) von Hotton, Emily J., Bale, Nichola, Rose, Claire, White, Paul, Wade, Julia, Mottet, Nicolas, Loose, Abi J., Elhodaiby, Mohamed, Lenguerrand, Erik, Draycott, Tim J., Crofts, Joanna F., Algeo, Mike, Alvarez, Mary, Arulkumaran, Sabaratnam, Bale, Nichola, Blencowe, Natalie S., Collins, Kate, Crofts, Joanna F., Day, Fiona, Deacon, Elizabeth, Draycott, Timothy J., ElHodaiby, Mohamed, Exell, Lily, Gamaledin, Islam, Glover, Anne, Grant, Simon, Hall, Sally, Hinton, Cameron, Hotton, Emily J., Kamali, Hajeb, Kirk, Lisa, Lawson, Carolyn, Lenguerrand, Erik, Lewis-White, Helen, Loose, Abi, Mallinson, Naomi, Mettam, Katie, Mola, Glen, O’Brien, Stephen, Pike, Alison, Powell, Rachel, Reading, Iona, Rose, Claire, Wade, Julia, Walpole, Kathryn, White, Paul, Winter, Cathy, Woods, Karen

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Telehealth vs In-Person Early Palliative Care for Patients With Advanced Lung Cancer: A Multisite Randomized Clinical Trial von Greer, Joseph A, Temel, Jennifer S, El-Jawahri, Areej, Rinaldi, Simone, Kamdar, Mihir, Park, Elyse R, Horick, Nora K, Pintro, Kedie, Rabideau, Dustin J, Schwamm, Lee, Feliciano, Josephine, Chua, Isaac, Leventakos, Konstantinos, Fischer, Stacy M, Campbell, Toby C, Rabow, Michael W, Zachariah, Finly, Hanson, Laura C, Martin, Sara F, Silveira, Maria, Shoemaker, Laura, Bakitas, Marie, Bauman, Jessica, Spoozak, Lori, Grey, Carl, Blackhall, Leslie, Curseen, Kimberly, O’Mahony, Sean, Smith, Melanie M, Rhodes, Ramona, Cullinan, Amelia, Jackson, Vicki

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Physical Activity, Mental Health and Wellbeing of Adults within and during the Easing of COVID-19 Restrictions, in the United Kingdom and New Zealand von Faulkner, James, O'Brien, Wendy J, Stuart, Beth, Stoner, Lee, Batten, John, Wadsworth, Daniel, Askew, Christopher D, Badenhorst, Claire E, Byrd, Erin, Draper, Nick, Elliot, Catherine, Fryer, Simon, Hamlin, Michael J, Jakeman, John R, Mackintosh, Kelly A, McNarry, Melitta A, Mitchelmore, Andrew, Ryan-Stewart, Helen, Saynor, Zoe, Schaumberg, Mia A, Spiegelhalter, Emily, Stone, Keeron, Lambrick, Danielle

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Does longer peripheral intravenous catheter length optimise antimicrobial delivery? A randomised controlled trial von Corley, Amanda, O'Brien, Catherine, Wignall, Elizabeth, Peach, Hannah, Larsen, Emily, Rickard, Claire, Hewer, Barbara, Marsh, Nicole

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A comparison of hydrophobic polyurethane and polyurethane peripherally inserted central catheter: results from a feasibility randomized controlled trial von Gavin, Nicole C, Kleidon, Tricia M, Larsen, Emily, O'Brien, Catherine, Ullman, Amanda, Northfield, Sarah, Mihala, Gabor, Runnegar, Naomi, Marsh, Nicole, Rickard, Claire M

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