Mechanical Forces Have a Range of Effects on the Rate of Ribosome Catalyzed Peptidyl Transfer Depending on Direction von Jiang, Yang, O’Brien, Edward P

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Domain topology, stability, and translation speed determine mechanical force generation on the ribosome von Leininger, Sarah E., Trovato, Fabio, Nissley, Daniel A., O’Brien, Edward P.

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Non-equilibrium coupling of protein structure and function to translation–elongation kinetics von Sharma, Ajeet K, O’Brien, Edward P

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Timing Is Everything: Unifying Codon Translation Rates and Nascent Proteome Behavior von Nissley, Daniel A, O’Brien, Edward P

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Computing the functional proteome: recent progress and future prospects for genome-scale models von O’Brien, Edward J, Palsson, Bernhard O

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Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding von Döring, Kristina, Ahmed, Nabeel, Riemer, Trine, Suresh, Harsha Garadi, Vainshtein, Yevhen, Habich, Markus, Riemer, Jan, Mayer, Matthias P., O’Brien, Edward P., Kramer, Günter, Bukau, Bernd

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Electrostatic Interactions Explain the Higher Binding Affinity of the CR3022 Antibody for SARS-CoV‑2 than the 4A8 Antibody von Nguyen, Hung, Lan, Pham Dang, Nissley, Daniel A, O’Brien, Edward P, Li, Mai Suan

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Structural Origins of FRET-Observed Nascent Chain Compaction on the Ribosome von Nissley, Daniel A, O’Brien, Edward P

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Incorporating mutational heterogeneity to identify genes that are enriched for synonymous mutations in cancer von Rao, Yiyun, Ahmed, Nabeel, Pritchard, Justin, O'Brien, Edward P

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Genome‐scale models of metabolism and gene expression extend and refine growth phenotype prediction von O'Brien, Edward J, Lerman, Joshua A, Chang, Roger L, Hyduke, Daniel R, Palsson, Bernhard Ø

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Updating during Reading Comprehension: Why Causality Matters von Kendeou, Panayiota, Smith, Emily R, O'Brien, Edward J

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Insights into Cotranslational Nascent Protein Behavior from Computer Simulations von Trovato, Fabio, O'Brien, Edward P

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It is theoretically possible to avoid misfolding into non-covalent lasso entanglements using small molecule drugs von Jiang, Yang, Deane, Charlotte M, Morris, Garrett M, O'Brien, Edward P

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Multi-omic data integration enables discovery of hidden biological regularities von Ebrahim, Ali, Brunk, Elizabeth, Tan, Justin, O'Brien, Edward J., Kim, Donghyuk, Szubin, Richard, Lerman, Joshua A., Lechner, Anna, Sastry, Anand, Bordbar, Aarash, Feist, Adam M., Palsson, Bernhard O.

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Origins of the Mechanochemical Coupling of Peptide Bond Formation to Protein Synthesis von Fritch, Benjamin, Kosolapov, Andrey, Hudson, Phillip, Nissley, Daniel A, Woodcock, H. Lee, Deutsch, Carol, O’Brien, Edward P

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Physical Origins of Codon Positions That Strongly Influence Cotranslational Folding: A Framework for Controlling Nascent-Protein Folding von Sharma, Ajeet K, Bukau, Bernd, O’Brien, Edward P

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Interactions between Hydrophobic and Ionic Solutes in Aqueous Guanidinium Chloride and Urea Solutions:  Lessons for Protein Denaturation Mechanism von O'Brien, Edward P, Dima, Ruxandra I, Brooks, Bernard, Thirumalai, D

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Is Posttranslational Folding More Efficient Than Refolding from a Denatured State: A Computational Study von Vu, Quyen V., Nissley, Daniel A., Jiang, Yang, O’Brien, Edward P., Li, Mai Suan

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Pulling Forces Differentially Affect Refolding Pathways Due to Entangled Misfolded States in SARS-CoV-1 and SARS-CoV-2 Receptor Binding Domain von Lan, Pham Dang, O'Brien, Edward P, Li, Mai Suan

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Processing real-world violations embedded within a fantasy-world narrative von Walsh, Erinn K, Cook, Anne E, O’Brien, Edward J

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