Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial von Paz-Ares, L., Tan, E.-H., O’Byrne, K., Zhang, L., Hirsh, V., Boyer, M., Yang, J.C.-H., Mok, T., Lee, K.H., Lu, S., Shi, Y., Lee, D.H., Laskin, J., Kim, D.-W., Laurie, S.A., Kölbeck, K., Fan, J., Dodd, N., Märten, A., Park, K.

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Targeting nuclear factor-kappa B to overcome resistance to chemotherapy von Godwin, P, Baird, A M, Heavey, S, Barr, M P, O'Byrne, K J, Gately, K

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Poor patient outcome correlates with active engulfment of cytokeratin positive CTCs within cancer-associated monocyte population in lung cancer von Wiegmans, A. P., Ivanova, E., Naei, V. Y., Monkman, J., Fletcher, J., Mullally, W., Warkiani, M. E., O’Byrne, K., Kulasinghe, A.

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Relative Importance of the Arcuate and Anteroventral Periventricular Kisspeptin Neurons in Control of Puberty and Reproductive Function in Female Rats von Hu, M. H, Li, X. F, McCausland, B, Li, S. Y, Gresham, R, Kinsey-Jones, J. S, Gardiner, J. V, Sam, A. H, Bloom, S. R, Poston, L, Lightman, S. L, Murphy, K. G, O'Byrne, K. T

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Chronic immune activation and inflammation as the cause of malignancy von O'BYRNE, K. J, DALGLEISH, A. G

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Kisspeptin neurones in the posterodorsal medial amygdala modulate sexual partner preference and anxiety in male mice von Adekunbi, D. A., Li, X. F., Lass, G., Shetty, K., Adegoke, O. A., Yeo, S. H., Colledge, W. H., Lightman, S. L., O'Byrne, K. T.

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Second ESMO consensus conference on lung cancer: pathology and molecular biomarkers for non-small-cell lung cancer von Kerr, K.M., Bubendorf, L., Edelman, M.J., Marchetti, A., Mok, T., Novello, S., O'Byrne, K., Stahel, R., Peters, S., Felip, E., Stahel, Rolf, Felip, Enriqueta, Peters, Solange, Kerr, Keith, Besse, Benjamin, Vansteenkiste, Johan, Eberhardt, Wilfried, Edelman, Martin, Mok, Tony, O'Byrne, Ken, Novello, Silvia, Bubendorf, Lukas, Marchetti, Antonio, Baas, Paul, Reck, Martin, Syrigos, Konstantinos, Paz-Ares, Luis, Smit, Egbert F., Meldgaard, Peter, Adjei, Alex, Nicolson, Marianne, Crinò, Lucio, Van Schil, Paul, Senan, Suresh, Faivre-Finn, Corinne, Rocco, Gaetano, Veronesi, Giulia, Douillard, Jean-Yves, Lim, Eric, Dooms, Christophe, Weder, Walter, De Ruysscher, Dirk, Le Pechoux, Cecile, De Leyn, Paul, Westeel, Virginie

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Suppression of the GnRH Pulse Generator by Neurokinin B Involves a κ-Opioid Receptor-Dependent Mechanism von Grachev, P, Li, X. F, Kinsey-Jones, J. S, di Domenico, A. L, Millar, R. P, Lightman, S. L, O'Byrne, K. T

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Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung ca... von Rosell, R., Robinet, G., Szczesna, A., Ramlau, R., Constenla, M., Mennecier, B. C., Pfeifer, W., O'Byrne, K. J., Welte, T., Kolb, R., Pirker, R., Chemaissani, A., Perol, M., Ranson, M. R., Ellis, P. A., Pilz, K., Reck, M.

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The Posterodorsal Medial Amygdala Regulates the Timing of Puberty Onset in Female Rats von Li, X. F, Hu, M. H, Hanley, B. P, Lin, Y. S, Poston, L, Lightman, S. L, O'Byrne, K. T

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Effect of dose adjustment on the safety and efficacy of afatinib for EGFR mutation-positive lung adenocarcinoma: post hoc analyses of the randomized LUX-Lung 3 and 6 trials von Yang, J.C.-H., Sequist, L.V., Zhou, C., Schuler, M., Geater, S.L., Mok, T., Hu, C.-P., Yamamoto, N., Feng, J., O'Byrne, K., Lu, S., Hirsh, V., Huang, Y., Sebastian, M., Okamoto, I., Dickgreber, N., Shah, R., Märten, A., Massey, D., Wind, S., Wu, Y.-L.

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Bone matters in lung cancer von Brodowicz, T., O'Byrne, K., Manegold, C.

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Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: A verification study von Gately, K, Al-Alao, B, T.Dhillon, Mauri, F, Cuffe, S, Seckl, M, O’Byrne, K

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Long-term survival with first-line nivolumab plus ipilimumab in patients with advanced non-small-cell lung cancer: a pooled analysis von Borghaei, H., Ciuleanu, T.-E., Lee, J.-S., Pluzanski, A., Caro, R. Bernabe, Gutierrez, M., Ohe, Y., Nishio, M., Goldman, J., Ready, N., Spigel, D.R., Ramalingam, S.S., Paz-Ares, L.G., Gainor, J.F., Ahmed, S., Reck, M., Maio, M., O’Byrne, K.J., Memaj, A., Nathan, F., Tran, P., Hellmann, M.D., Brahmer, J.R.

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Neurokinin B Signaling in the Female Rat: a Novel Link Between Stress and Reproduction von Grachev, P, Li, X.F, Hu, M.H, Li, S.Y, Millar, R.P, Lightman, S.L, O'Byrne, K.T

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The Role of Neurokinin B Signalling in Reproductive Neuroendocrinology von Grachev, P., Millar, R.P., O'Byrne, K.T.

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Neonatal Lipopolysaccharide Exposure Delays Puberty and Alters Hypothalamic Kiss1 and Kiss1r mRNA Expression in the Female Rat von Knox, A. M. I., Li, X. F., Kinsey-Jones, J. S., Wilkinson, E. S., Wu, X. Q., Cheng, Y.S., Milligan, S. R., Lightman, S. L., O'Byrne, K. T.

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Down-Regulation of Hypothalamic Kisspeptin and its Receptor, Kiss1r, mRNA Expression is Associated with Stress-Induced Suppression of Luteinising Hormone Secretion in the Female Ra... von Kinsey-Jones, J. S., Li, X. F., Knox, A. M. I., Wilkinson, E. S., Zhu, X. L., Chaudhary, A. A., Milligan, S. R., Lightman, S. L., O'Byrne, K. T.

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Neonatal Lipopolysaccharide Exposure Exacerbates Stress-Induced Suppression of Luteinizing Hormone Pulse Frequency in Adulthood von Li, X. F, Kinsey-Jones, J. S, Knox, A. M. I, Wu, X. Q, Tahsinsoy, D, Brain, S. D, Lightman, S. L, O’Byrne, K. T

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Kisspeptin stimulation of insulin secretion: mechanisms of action in mouse islets and rats von Bowe, J. E., King, A. J., Kinsey-Jones, J. S., Foot, V. L., Li, X. F., O’Byrne, K. T., Persaud, S. J., Jones, P. M.

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