Conformational Abs Recognizing a Generic Amyloid Fibril Epitope von O'Nuallain, Brian, Wetzel, Ronald

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Seeding Specificity in Amyloid Growth Induced by Heterologous Fibrils von O'Nuallain, Brian, Williams, Angela D., Westermark, Per, Wetzel, Ronald

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Physiological IgM Class Catalytic Antibodies Selective for Transthyretin Amyloid von Planque, Stephanie A., Nishiyama, Yasuhiro, Hara, Mariko, Sonoda, Sari, Murphy, Sarah K., Watanabe, Kenji, Mitsuda, Yukie, Brown, Eric L., Massey, Richard J., Primmer, Stanley R., O'Nuallain, Brian, Paul, Sudhir

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Kinetics and Thermodynamics of Amyloid Assembly Using a High‐Performance Liquid Chromatography–Based Sedimentation Assay von O'Nuallain, Brian, Thakur, Ashwani K., Williams, Angela D., Bhattacharyya, Anusri M., Chen, Songming, Thiagarajan, Geetha, Wetzel, Ronald

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IgG Conformer's Binding to Amyloidogenic Aggregates von Phay, Monichan, Welzel, Alfred T, Williams, Angela D, McWilliams-Koeppen, Helen P, Blinder, Veronika, O'Malley, Tiernan T, Solomon, Alan, Walsh, Dominic M, O'Nuallain, Brian

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Diagnostic and Therapeutic Potential of Amyloid-Reactive IgG Antibodies Contained in Human Sera von O'Nuallain, Brian, Hrncic, Rudi, Wall, Jonathan S, Weiss, Deborah T, Solomon, Alan

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An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease von Jin, Ming, O’Nuallain, Brian, Hong, Wei, Boyd, Justin, Lagomarsino, Valentina N., O’Malley, Tiernan T., Liu, Wen, Vanderburg, Charles R., Frosch, Matthew P., Young-Pearse, Tracy, Selkoe, Dennis J., Walsh, Dominic M.

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Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice von Mably, Alexandra J, Liu, Wen, Mc Donald, Jessica M, Dodart, Jean-Cosme, Bard, Frédérique, Lemere, Cynthia A, O'Nuallain, Brian, Walsh, Dominic M

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Transthyretin Aggregate-Specific Antibodies Recognize Cryptic Epitopes on Patient-Derived Amyloid Fibrils von Phay, Monichan, Blinder, Veronika, Macy, Sallie, Greene, Michael J., Wooliver, Daniel C., Liu, Wen, Planas, Antoni, Walsh, Dominic M., Connors, Lawreen H., Primmer, Stanley R., Planque, Stephanie A., Paul, Sudhir, O'Nuallain, Brian

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Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites von Tokarew, Jacqueline M., El-Kodsi, Daniel N., Lengacher, Nathalie A., Fehr, Travis K., Nguyen, Angela P., Shutinoski, Bojan, O’Nuallain, Brian, Jin, Ming, Khan, Jasmine M., Ng, Andy C. H., Li, Juan, Jiang, Qiubo, Zhang, Mei, Wang, Liqun, Sengupta, Rajib, Barber, Kathryn R., Tran, An, Im, Doo Soon, Callaghan, Steve, Park, David S., Zandee, Stephanie, Dong, Xiajun, Scherzer, Clemens R., Prat, Alexandre, Tsai, Eve C., Takanashi, Masashi, Hattori, Nobutaka, Chan, Jennifer A., Zecca, Luigi, West, Andrew B., Holmgren, Arne, Puente, Lawrence, Shaw, Gary S., Toth, Gergely, Woulfe, John M., Taylor, Peggy, Tomlinson, Julianna J., Schlossmacher, Michael G.

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Preclinical Efficacy of VTX-0811: A Humanized First-in-Class PSGL-1 mAb Targeting TAMs to Suppress Tumor Growth von Novobrantseva, Tatiana, Manfra, Denise, Ritter, Jessica, Razlog, Maja, O'Nuallain, Brian, Zafari, Mohammad, Nowakowska, Dominika, Basinski, Sara, Phennicie, Ryan T, Nguyen, Phuong A, Brehm, Michael A, Sazinsky, Stephen, Feldman, Igor

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Thermodynamics of Aβ(1−40) Amyloid Fibril Elongation von O'Nuallain, Brian, Shivaprasad, Shankaramma, Kheterpal, Indu, Wetzel, Ronald

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Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies von O'Malley, Tiernan T, Oktaviani, Nur Alia, Zhang, Dainan, Lomakin, Aleksey, O'Nuallain, Brian, Linse, Sara, Benedek, George B, Rowan, Michael J, Mulder, Frans A A, Walsh, Dominic M

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Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice von Crehan, Helen, Liu, Bin, Kleinschmidt, Martin, Rahfeld, Jens-Ulrich, Le, Kevin X, Caldarone, Barbara J, Frost, Jeffrey L, Hettmann, Thore, Hutter-Paier, Birgit, O'Nuallain, Brian, Park, Mi-Ae, DiCarli, Marcelo F, Lues, Inge, Schilling, Stephan, Lemere, Cynthia A

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Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils von O'Nuallain, Brian, Freir, Darragh B, Nicoll, Andrew J, Risse, Emmanuel, Ferguson, Neil, Herron, Caroline E, Collinge, John, Walsh, Dominic M

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Human anti-Aβ IgGs target conformational epitopes on synthetic dimer assemblies and the AD brain-derived peptide von Welzel, Alfred T, Williams, Angela D, McWilliams-Koeppen, Helen P, Acero, Luis, Weber, Alfred, Blinder, Veronika, Mably, Alex, Bunk, Sebastian, Hermann, Corinna, Farrell, Michael A, Ehrlich, Hartmut J, Schwarz, Hans P, Walsh, Dominic M, Solomon, Alan, O'Nuallain, Brian

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Abstract P107: PSGL-1 blocking antibodies repolarize tumor associated macrophages, reduce suppressive myeloid populations and induce inflammation in the tumor microenvironment, lea... von Nguyen, Ani, Ritter, Jessica, Zafari, Mohammad, Manfra, Denise, Komoroski, Veronica, O'Nuallain, Brian, Phennicie, Ryan, Kauffman, Kevin, Nowakowska, Dominika, Wahle, Joe, Sazinsky, Steve, Brehm, Michael, Feldman, Igor, Novobrantseva, Tatiana

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A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo von Levites, Yona, O'Nuallain, Brian, Puligedda, Rama Devudu, Ondrejcak, Tomas, Adekar, Sharad P, Chen, Cindy, Cruz, Pedro E, Rosario, Awilda M, Macy, Sallie, Mably, Alexandra J, Walsh, Dominic M, Vidal, Ruben, Solomon, Alan, Brown, Daniel, Rowan, Michael J, Golde, Todd E, Dessain, Scott K

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ANTI-N-TERMINAL ABETA MAB 3A1 PREFERENTIALLY RECOGNIZES ABETA AGGREGATES AND DOES NOT CROSS-REACT WITH APP von Frost, Jeffrey L., Foster, James S., Taylor, Peggy, O'Nuallain, Brian

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An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice von Frost, Jeffrey L, Liu, Bin, Rahfeld, Jens-Ulrich, Kleinschmidt, Martin, O'Nuallain, Brian, Le, Kevin X, Lues, Inge, Caldarone, Barbara J, Schilling, Stephan, Demuth, Hans-Ulrich, Lemere, Cynthia A

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