PPARγ and PPARα synergize to induce robust browning of white fat in vivo von Kroon, Tobias, Harms, Matthew, Maurer, Stefanie, Bonnet, Laurianne, Alexandersson, Ida, Lindblom, Anna, Ahnmark, Andrea, Nilsson, Daniel, Gennemark, Peter, O'Mahony, Gavin, Osinski, Victoria, McNamara, Coleen, Boucher, Jeremie

Volltext

Adipose Tissue–Preserved Skin Graft: Applicability and Long-Term Results von Chung, Bryan, O’Mahony, Gavin D., Lam, Gretl, Chiu, David T. W.

Volltext

Efficacy of Dorsoradial Capsulodesis for Trapeziometacarpal Joint Instability: A Cadaver Study von Chenoweth, Brian A., MD, O'Mahony, Gavin D., MD, Fitzgerald, Casey, BS, Stoner, Julie A., PhD, O'Donoghue, Daniel L., PhD, Rayan, Ghazi M., MD

Volltext

Modulators of 14-3‑3 Protein–Protein Interactions von Stevers, Loes M, Sijbesma, Eline, Botta, Maurizio, MacKintosh, Carol, Obsil, Tomas, Landrieu, Isabelle, Cau, Ylenia, Wilson, Andrew J, Karawajczyk, Anna, Eickhoff, Jan, Davis, Jeremy, Hann, Michael, O’Mahony, Gavin, Doveston, Richard G, Brunsveld, Luc, Ottmann, Christian

Volltext

Synthesis and photophysical properties of novel cyclonucleosides—substituent effects on fluorescence emission von O'Mahony, Gavin, Ehrman, Eleonor, Grøtli, Morten

Volltext

Chronic treatment with terbutaline increases glucose and oleic acid oxidation and protein synthesis in cultured human myotubes von Skagen, Christine, Nyman, Tuula A., Peng, Xiao-Rong, O'Mahony, Gavin, Kase, Eili Tranheim, Rustan, Arild Chr, Thoresen, G. Hege

Volltext

NMR-Based Substrate Analog Docking to Escherichia coli Peptidyl-tRNA Hydrolase von Giorgi, Laurent, Plateau, Pierre, O'Mahony, Gavin, Aubard, Caroline, Fromant, Michel, Thureau, Aurélien, Grøtli, Morten, Blanquet, Sylvain, Bontems, François

Volltext

Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects von Bauknight, Dustin K, Osinski, Victoria, Dasa, Siva Sai Krishna, Nguyen, Anh T, Marshall, Melissa A, Hartman, Julia, Harms, Matthew, O'Mahony, Gavin, Boucher, Jeremie, Klibanov, Alexander L, McNamara, Coleen A, Kelly, Kimberly A

Volltext

Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction von Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin

Volltext

N‑Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let‑7 Interaction von Borgelt, Lydia, Hohnen, Lisa, Pallesen, Jakob S., Hommen, Pascal, Goebel, Georg L., Bosica, Francesco, Liu, Yang, O’Mahony, Gavin, Wu, Peng

Volltext

Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and Obesity von Peng, Xiao-Rong, Gennemark, Peter, O'Mahony, Gavin, Bartesaghi, Stefano

Volltext

Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction” von Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin

Volltext

Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation von O’Mahony, Gavin, Petersen, Jens, Ek, Margareta, Rae, Rebecca, Johansson, Carina, Jianming, Liu, Prokoph, Nina, Bergström, Fredrik, Bamberg, Krister, Giordanetto, Fabrizio, Zarrouki, Bader, Karlsson, Daniel, Hogner, Anders

Volltext

Synthesis of Tertiary Amides from Anionically Activated Aromatic Trifluoromethyl Groups von O’Mahony, Gavin, Pitts, Andrew K.

Volltext

Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection von Granberg, Kenneth L, Yuan, Zhong-Qing, Lindmark, Bo, Edman, Karl, Kajanus, Johan, Hogner, Anders, Malmgren, Marcus, O’Mahony, Gavin, Nordqvist, Anneli, Lindberg, Jan, Tångefjord, Stefan, Kossenjans, Michael, Löfberg, Christian, Brånalt, Jonas, Liu, Dongmei, Selmi, Nidhal, Nikitidis, Grigorios, Nordberg, Peter, Hayen, Ahlke, Aagaard, Anna, Hansson, Eva, Hermansson, Majlis, Ivarsson, Ida, Jansson-Löfmark, Rasmus, Karlsson, Ulla, Johansson, Ulrika, William-Olsson, Lena, Hartleib-Geschwindner, Judith, Bamberg, Krister

Volltext

In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects von Osinski, Victoria, Bauknight, Dustin K, Dasa, Siva Sai Krishna, Harms, Matthew J, Kroon, Tobias, Marshall, Melissa A, Garmey, James C, Nguyen, Anh T, Hartman, Julia, Upadhye, Aditi, Srikakulapu, Prasad, Zhou, Andrea, O'Mahony, Gavin, Klibanov, Alexander L, Kelly, Kimberly A, Boucher, Jeremie, McNamara, Coleen A

Volltext

Design of Drug‐Like Protein–Protein Interaction Stabilizers Guided By Chelation‐Controlled Bioactive Conformation Stabilization von Bosica, Francesco, Andrei, Sebastian A., Neves, João Filipe, Brandt, Peter, Gunnarsson, Anders, Landrieu, Isabelle, Ottmann, Christian, O'Mahony, Gavin

Volltext

A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes von Park, Se-Hyung, Helsley, Robert N., Noetzli, Leila, Tu, Ho-Chou, Wallenius, Kristina, O’Mahony, Gavin, Boucher, Jeremie, Liu, Jianming, Softic, Samir

Volltext

Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors von Bauer, Udo, Giordanetto, Fabrizio, Bauer, Martin, O’Mahony, Gavin, Johansson, Kjell E., Knecht, Wolfgang, Hartleib-Geschwindner, Judith, Carlsson, Eva Töppner, Enroth, Cristofer

Volltext

Phosphorylated full‐length Tau interacts with 14‐3‐3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14‐3‐3 dimer von Neves, João Filipe, Petrvalská, Olivia, Bosica, Francesco, Cantrelle, François‐Xavier, Merzougui, Hamida, O'Mahony, Gavin, Hanoulle, Xavier, Obšil, Tomáš, Landrieu, Isabelle

Volltext