Immune Escape of Relapsed AML Cells after Allogeneic Transplantation von Christopher, Matthew J, Petti, Allegra A, Rettig, Michael P, Miller, Christopher A, Chendamarai, Ezhilarasi, Duncavage, Eric J, Klco, Jeffery M, Helton, Nicole M, O’Laughlin, Michelle, Fronick, Catrina C, Fulton, Robert S, Wilson, Richard K, Wartman, Lukas D, Welch, John S, Heath, Sharon E, Baty, Jack D, Payton, Jacqueline E, Graubert, Timothy A, Link, Daniel C, Walter, Matthew J, Westervelt, Peter, Ley, Timothy J, DiPersio, John F

Volltext

Genome remodelling in a basal-like breast cancer metastasis and xenograft von Wilson, Richard K, Ding, Li, Ellis, Matthew J, Li, Shunqiang, Larson, David E, Chen, Ken, Wallis, John W, Harris, Christopher C, McLellan, Michael D, Fulton, Robert S, Fulton, Lucinda L, Abbott, Rachel M, Hoog, Jeremy, Dooling, David J, Koboldt, Daniel C, Schmidt, Heather, Kalicki, Joelle, Zhang, Qunyuan, Chen, Lei, Lin, Ling, Wendl, Michael C, McMichael, Joshua F, Magrini, Vincent J, Cook, Lisa, McGrath, Sean D, Vickery, Tammi L, Appelbaum, Elizabeth, DeSchryver, Katherine, Davies, Sherri, Guintoli, Therese, Lin, Li, Crowder, Robert, Tao, Yu, Snider, Jacqueline E, Smith, Scott M, Dukes, Adam F, Sanderson, Gabriel E, Pohl, Craig S, Delehaunty, Kim D, Fronick, Catrina C, Pape, Kimberley A, Reed, Jerry S, Robinson, Jody S, Hodges, Jennifer S, Schierding, William, Dees, Nathan D, Shen, Dong, Locke, Devin P, Wiechert, Madeline E, Eldred, James M, Peck, Josh B, Oberkfell, Benjamin J, Lolofie, Justin T, Du, Feiyu, Hawkins, Amy E, O’Laughlin, Michelle D, Bernard, Kelly E, Cunningham, Mark, Elliott, Glendoria, Mason, Mark D, Thompson Jr, Dominic M, Ivanovich, Jennifer L, Goodfellow, Paul J, Perou, Charles M, Weinstock, George M, Aft, Rebecca, Watson, Mark, Ley, Timothy J, Mardis, Elaine R

Volltext

Clonal Architecture of Secondary Acute Myeloid Leukemia von Walter, Matthew J, Shen, Dong, Ding, Li, Shao, Jin, Koboldt, Daniel C, Chen, Ken, Larson, David E, McLellan, Michael D, Dooling, David, Abbott, Rachel, Fulton, Robert, Magrini, Vincent, Schmidt, Heather, Kalicki-Veizer, Joelle, O'Laughlin, Michelle, Fan, Xian, Grillot, Marcus, Witowski, Sarah, Heath, Sharon, Frater, John L, Eades, William, Tomasson, Michael, Westervelt, Peter, DiPersio, John F, Link, Daniel C, Mardis, Elaine R, Ley, Timothy J, Wilson, Richard K, Graubert, Timothy A

Volltext

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes von Graubert, Timothy A, Shen, Dong, Ding, Li, Okeyo-Owuor, Theresa, Lunn, Cara L, Shao, Jin, Krysiak, Kilannin, Harris, Christopher C, Koboldt, Daniel C, Larson, David E, McLellan, Michael D, Dooling, David J, Abbott, Rachel M, Fulton, Robert S, Schmidt, Heather, Kalicki-Veizer, Joelle, O'Laughlin, Michelle, Grillot, Marcus, Baty, Jack, Heath, Sharon, Frater, John L, Nasim, Talat, Link, Daniel C, Tomasson, Michael H, Westervelt, Peter, DiPersio, John F, Mardis, Elaine R, Ley, Timothy J, Wilson, Richard K, Walter, Matthew J

Volltext

CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression von Spencer, David H., Russler-Germain, David A., Ketkar, Shamika, Helton, Nichole M., Lamprecht, Tamara L., Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Shinawi, Marwan, Westervelt, Peter, Payton, Jacqueline E., Wartman, Lukas D., Welch, John S., Wilson, Richard K., Walter, Matthew J., Link, Daniel C., DiPersio, John F., Ley, Timothy J.

Volltext

Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia von Klco, Jeffery M., Spencer, David H., Miller, Christopher A., Griffith, Malachi, Lamprecht, Tamara L., O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Fulton, Robert S., Eades, William C., Link, Daniel C., Graubert, Timothy A., Walter, Matthew J., Mardis, Elaine R., Dipersio, John F., Wilson, Richard K., Ley, Timothy J.

Volltext

Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia von Churpek, Jane E., Pyrtel, Khateriaa, Kanchi, Krishna-Latha, Shao, Jin, Koboldt, Daniel, Miller, Christopher A., Shen, Dong, Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Pusic, Iskra, Uy, Geoffrey L., Braunstein, Evan M., Levis, Mark, Ross, Julie, Elliott, Kevin, Heath, Sharon, Jiang, Allan, Westervelt, Peter, DiPersio, John F., Link, Daniel C., Walter, Matthew J., Welch, John, Wilson, Richard, Ley, Timothy J., Godley, Lucy A., Graubert, Timothy A.

Volltext

Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia von Klco, Jeffery M, Miller, Christopher A, Griffith, Malachi, Petti, Allegra, Spencer, David H, Ketkar-Kulkarni, Shamika, Wartman, Lukas D, Christopher, Matthew, Lamprecht, Tamara L, Helton, Nicole M, Duncavage, Eric J, Payton, Jacqueline E, Baty, Jack, Heath, Sharon E, Griffith, Obi L, Shen, Dong, Hundal, Jasreet, Chang, Gue Su, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T, Larson, David E, Kulkarni, Shashikant, Ozenberger, Bradley A, Welch, John S, Walter, Matthew J, Graubert, Timothy A, Westervelt, Peter, Radich, Jerald P, Link, Daniel C, Mardis, Elaine R, DiPersio, John F, Wilson, Richard K, Ley, Timothy J

Volltext

Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome von Shirai, Cara Lunn, White, Brian S., Tripathi, Manorama, Tapia, Roberto, Ley, James N., Ndonwi, Matthew, Kim, Sanghyun, Shao, Jin, Carver, Alexa, Saez, Borja, Fulton, Robert S., Fronick, Catrina, O’Laughlin, Michelle, Lagisetti, Chandraiah, Webb, Thomas R., Graubert, Timothy A., Walter, Matthew J.

Volltext

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo von Shirai, Cara Lunn, Ley, James N., White, Brian S., Kim, Sanghyun, Tibbitts, Justin, Shao, Jin, Ndonwi, Matthew, Wadugu, Brian, Duncavage, Eric J., Okeyo-Owuor, Theresa, Liu, Tuoen, Griffith, Malachi, McGrath, Sean, Magrini, Vincent, Fulton, Robert S., Fronick, Catrina, O’Laughlin, Michelle, Graubert, Timothy A., Walter, Matthew J.

Volltext

DNMT3A Mutations in Acute Myeloid Leukemia von Ley, Timothy J, Ding, Li, Walter, Matthew J, McLellan, Michael D, Lamprecht, Tamara, Larson, David E, Kandoth, Cyriac, Payton, Jacqueline E, Baty, Jack, Welch, John, Harris, Christopher C, Lichti, Cheryl F, Townsend, R. Reid, Fulton, Lucinda A, Fulton, Robert S, Dooling, David J, Koboldt, Daniel C, Schmidt, Heather, Zhang, Qunyuan, Osborne, John R, Lin, Ling, O'Laughlin, Michelle, McMichael, Joshua F, Delehaunty, Kim D, McGrath, Sean D, Magrini, Vincent J, Vickery, Tammi L, Hundal, Jasreet, Cook, Lisa L, Conyers, Joshua J, Swift, Gary W, Reed, Jerry P, Alldredge, Patricia A, Wylie, Todd, Walker, Jason, Kalicki, Joelle, Watson, Mark A, Heath, Sharon, Shannon, William D, Varghese, Nobish, Nagarajan, Rakesh, Westervelt, Peter, Tomasson, Michael H, Link, Daniel C, Graubert, Timothy A, DiPersio, John F, Mardis, Elaine R, Wilson, Richard K

Volltext

Shared cell of origin in a patient with Erdheim-Chester disease and acute myeloid leukemia von Ghobadi, Armin, Miller, Christopher A, Li, Tiandao, O'Laughlin, Michelle, Lee, Yi-Shan, Ali, Mohga, Westervelt, Peter, DiPersio, John F, Wartman, Lukas

Volltext

Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response von Jacoby, Meagan A, Duncavage, Eric D, Khanna, Ajay, Chang, Gue Su, Nonavinkere Srivatsan, Sridhar, Miller, Christopher A, Gao, Feng, Robinson, Josh, Shao, Jin, Fulton, Robert S, Fronick, Catrina C, O'Laughlin, Michelle, Heath, Sharon E, Brendel, Kimberly, Chavez, Monique, DiPersio, John F, Abboud, Camille N, Stockerl-Goldstein, Keith, Westervelt, Peter, Cashen, Amanda, Pusic, Iskra, Oh, Stephen T, Welch, John S, Wells, Denise A, Loken, Michael R, Uy, Geoffrey L, Walter, Matthew J

Volltext

A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion von Miller, Christopher A., Tricarico, Christopher, Skidmore, Zachary L., Uy, Geoffrey L., Lee, Yi-Shan, Hassan, Anjum, O'Laughlin, Michelle D., Schmidt, Heather, Tian, Ling, Duncavage, Eric J., Griffith, Malachi, Griffith, Obi L., Welch, John S., Wartman, Lukas D.

Volltext

Identification of a Novel TP53 Cancer Susceptibility Mutation Through Whole-Genome Sequencing of a Patient With Therapy-Related AML von Link, Daniel C, Schuettpelz, Laura G, Shen, Dong, Wang, Jinling, Walter, Matthew J, Kulkarni, Shashikant, Payton, Jacqueline E, Ivanovich, Jennifer, Goodfellow, Paul J, Le Beau, Michelle, Koboldt, Daniel C, Dooling, David J, Fulton, Robert S, Bender, R. Hugh F, Fulton, Lucinda L, Delehaunty, Kimberly D, Fronick, Catrina C, Appelbaum, Elizabeth L, Schmidt, Heather, Abbott, Rachel, O’Laughlin, Michelle, Chen, Ken, McLellan, Michael D, Varghese, Nobish, Nagarajan, Rakesh, Heath, Sharon, Graubert, Timothy A, Ding, Li, Ley, Timothy J, Zambetti, Gerard P, Wilson, Richard K, Mardis, Elaine R

Volltext

Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy von Duncavage, Eric J., Uy, Geoffrey L., Petti, Allegra A., Miller, Christopher A., Lee, Yi-Shan, Tandon, Bevan, Gao, Feng, Fronick, Catrina C., O'Laughlin, Michelle, Fulton, Robert S., Wilson, Richard K., Jacoby, Meagan A., Cashen, Amanda F., Wartman, Lukas D., Walter, Matthew J., Westervelt, Peter, Link, Daniel C., DiPersio, John F., Ley, Timothy J., Welch, John S.

Volltext

Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant von Jacoby, Meagan A, Duncavage, Eric J, Chang, Gue Su, Miller, Christopher A, Shao, Jin, Elliott, Kevin, Robinson, Joshua, Fulton, Robert S, Fronick, Catrina C, O'Laughlin, Michelle, Heath, Sharon E, Pusic, Iskra, Welch, John S, Link, Daniel C, DiPersio, John F, Westervelt, Peter, Ley, Timothy J, Graubert, Timothy A, Walter, Matthew J

Volltext

Mutation Clearance after Transplantation for Myelodysplastic Syndrome von Duncavage, Eric J, Jacoby, Meagan A, Chang, Gue Su, Miller, Christopher A, Edwin, Natasha, Shao, Jin, Elliott, Kevin, Robinson, Joshua, Abel, Haley, Fulton, Robert S, Fronick, Catrina C, O’Laughlin, Michelle, Heath, Sharon E, Brendel, Kimberly, Saba, Raya, Wartman, Lukas D, Christopher, Matthew J, Pusic, Iskra, Welch, John S, Uy, Geoffrey L, Link, Daniel C, DiPersio, John F, Westervelt, Peter, Ley, Timothy J, Trinkaus, Kathryn, Graubert, Timothy A, Walter, Matthew J

Volltext

Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse von Li, Cheng, Klco, Jeffery M, Helton, Nichole M, George, Daniel R, Mudd, Jacqueline L, Miller, Christopher A, Lu, Charles, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Wilson, Richard K, Ley, Timothy J

Volltext

TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes von Welch, John S, Petti, Allegra A, Miller, Christopher A, Fronick, Catrina C, O’Laughlin, Michelle, Fulton, Robert S, Wilson, Richard K, Baty, Jack D, Duncavage, Eric J, Tandon, Bevan, Lee, Yi-Shan, Wartman, Lukas D, Uy, Geoffrey L, Ghobadi, Armin, Tomasson, Michael H, Pusic, Iskra, Romee, Rizwan, Fehniger, Todd A, Stockerl-Goldstein, Keith E, Vij, Ravi, Oh, Stephen T, Abboud, Camille N, Cashen, Amanda F, Schroeder, Mark A, Jacoby, Meagan A, Heath, Sharon E, Luber, Kierstin, Janke, Megan R, Hantel, Andrew, Khan, Niloufer, Sukhanova, Madina J, Knoebel, Randall W, Stock, Wendy, Graubert, Timothy A, Walter, Matthew J, Westervelt, Peter, Link, Daniel C, DiPersio, John F, Ley, Timothy J

Volltext