Comparative efficacy of a proprietary topical ibuprofen gel and oral ibuprofen in acute soft tissue injuries: a randomized, double-blind study von Whitefield, M., O'Kane, C. J. A., Anderson, S.

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A clinical audit of the Hakim programmable valve in patients with complex hydrocephalus von Kay, A D, Fisher, A J, O'Kane, C, Richards, H K, Pickard, J D

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Complex Inhibitory Effects of Nitric Oxide on Autophagy von Sarkar, Sovan, Korolchuk, Viktor I., Renna, Maurizio, Imarisio, Sara, Fleming, Angeleen, Williams, Andrea, Garcia-Arencibia, Moises, Rose, Claudia, Luo, Shouqing, Underwood, Benjamin R., Kroemer, Guido, O'Kane, Cahir J., Rubinsztein, David C.

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Percutaneous Revascularization for Ischemic Left Ventricular Dysfunction von Perera, Divaka, Clayton, Tim, O’Kane, Peter D., Greenwood, John P., Weerackody, Roshan, Ryan, Matthew, Morgan, Holly P., Dodd, Matthew, Evans, Richard, Canter, Ruth, Arnold, Sophie, Dixon, Lana J., Edwards, Richard J., De Silva, Kalpa, Spratt, James C., Conway, Dwayne, Cotton, James, McEntegart, Margaret, Chiribiri, Amedeo, Saramago, Pedro, Gershlick, Anthony, Shah, Ajay M., Clark, Andrew L., Petrie, Mark C.

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease von Rubinsztein, David C, Ravikumar, Brinda, Vacher, Coralie, Berger, Zdenek, Davies, Janet E, Luo, Shouqing, Oroz, Lourdes G, Scaravilli, Francesco, Easton, Douglas F, Duden, Rainer, O'Kane, Cahir J

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Rapamycin pre-treatment protects against apoptosis von Ravikumar, Brinda, Berger, Zdenek, Vacher, Coralie, O'Kane, Cahir J., Rubinsztein, David C.

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The paradox of matrix metalloproteinases in infectious disease von Elkington, P. T. G., O'Kane, C. M., Friedland, J. S.

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Performance and Implementation Evaluation of the Abbott BinaxNOW Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts von Pollock, Nira R, Jacobs, Jesica R, Tran, Kristine, Cranston, Amber E, Smith, Sita, O'Kane, Claire Y, Roady, Tyler J, Moran, Anne, Scarry, Alison, Carroll, Melissa, Volinsky, Leila, Perez, Gloria, Patel, Pinal, Gabriel, Stacey, Lennon, Niall J, Madoff, Lawrence C, Brown, Catherine, Smole, Sandra C

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Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling von Böhme, Mathias A, Beis, Christina, Reddy-Alla, Suneel, Reynolds, Eric, Mampell, Malou M, Grasskamp, Andreas T, Lützkendorf, Janine, Bergeron, Dominique Dufour, Driller, Jan H, Babikir, Husam, Göttfert, Fabian, Robinson, Iain M, O'Kane, Cahir J, Hell, Stefan W, Wahl, Markus C, Stelzl, Ulrich, Loll, Bernhard, Walter, Alexander M, Sigrist, Stephan J

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Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial von Aung, Kyaw L, Fischer, Sandra E, Denroche, Robert E, Jang, Gun-Ho, Dodd, Anna, Creighton, Sean, Southwood, Bernadette, Liang, Sheng-Ben, Chadwick, Dianne, Zhang, Amy, O'Kane, Grainne M, Albaba, Hamzeh, Moura, Shari, Grant, Robert C, Miller, Jessica K, Mbabaali, Faridah, Pasternack, Danielle, Lungu, Ilinca M, Bartlett, John M S, Ghai, Sangeet, Lemire, Mathieu, Holter, Spring, Connor, Ashton A, Moffitt, Richard A, Yeh, Jen Jen, Timms, Lee, Krzyzanowski, Paul M, Dhani, Neesha, Hedley, David, Notta, Faiyaz, Wilson, Julie M, Moore, Malcolm J, Gallinger, Steven, Knox, Jennifer J

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Rapamycin alleviates toxicity of different aggregate-prone proteins von Berger, Zdenek, Ravikumar, Brinda, Menzies, Fiona M., Oroz, Lourdes Garcia, Underwood, Benjamin R., Pangalos, Menelas N., Schmitt, Ina, Wullner, Ullrich, Evert, Bernd O., O'Kane, Cahir J., Rubinsztein, David C.

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Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS von Hamid, U, Krasnodembskaya, A, Fitzgerald, M, Shyamsundar, M, Kissenpfennig, A, Scott, C, Lefrancais, E, Looney, M R, Verghis, R, Scott, J, Simpson, A J, McNamee, J, McAuley, D F, O'Kane, C M

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Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity von Menzies, F M, Garcia-Arencibia, M, Imarisio, S, O'Sullivan, N C, Ricketts, T, Kent, B A, Rao, M V, Lam, W, Green-Thompson, Z W, Nixon, R A, Saksida, L M, Bussey, T J, O'Kane, C J, Rubinsztein, D C

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Dynein mutations impair autophagic clearance of aggregate-prone proteins von Rubinsztein, David C, Ravikumar, Brinda, Acevedo-Arozena, Abraham, Imarisio, Sara, Berger, Zdenek, Vacher, Coralie, O'Kane, Cahir J, Brown, Steve D M

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Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins von Yalçın, Belgin, Zhao, Lu, Stofanko, Martin, O'Sullivan, Niamh C, Kang, Zi Han, Roost, Annika, Thomas, Matthew R, Zaessinger, Sophie, Blard, Olivier, Patto, Alex L, Sohail, Anood, Baena, Valentina, Terasaki, Mark, O'Kane, Cahir J

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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin von Sarkar, Sovan, Krishna, Gauri, Imarisio, Sara, Saiki, Shinji, O'Kane, Cahir J., Rubinsztein, David C.

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Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution von Chan-Seng-Yue, Michelle, Kim, Jaeseung C., Wilson, Gavin W., Ng, Karen, Figueroa, Eugenia Flores, O’Kane, Grainne M., Connor, Ashton A., Denroche, Robert E., Grant, Robert C., McLeod, Jessica, Wilson, Julie M., Jang, Gun Ho, Zhang, Amy, Dodd, Anna, Liang, Sheng-Ben, Borgida, Ayelet, Chadwick, Dianne, Kalimuthu, Sangeetha, Lungu, Ilinca, Bartlett, John M. S., Krzyzanowski, Paul M., Sandhu, Vandana, Tiriac, Hervé, Froeling, Fieke E. M., Karasinska, Joanna M., Topham, James T., Renouf, Daniel J., Schaeffer, David F., Jones, Steven J. M., Marra, Marco A., Laskin, Janessa, Chetty, Runjan, Stein, Lincoln D., Zogopoulos, George, Haibe-Kains, Benjamin, Campbell, Peter J., Tuveson, David A., Knox, Jennifer J., Fischer, Sandra E., Gallinger, Steven, Notta, Faiyaz

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Sensitive tumour detection and classification using plasma cell-free DNA methylomes von Shen, Shu Yi, Singhania, Rajat, Fehringer, Gordon, Chakravarthy, Ankur, Roehrl, Michael H. A., Chadwick, Dianne, Zuzarte, Philip C., Borgida, Ayelet, Wang, Ting Ting, Li, Tiantian, Kis, Olena, Zhao, Zhen, Spreafico, Anna, Medina, Tiago da Silva, Wang, Yadon, Roulois, David, Ettayebi, Ilias, Chen, Zhuo, Chow, Signy, Murphy, Tracy, Arruda, Andrea, O’Kane, Grainne M., Liu, Jessica, Mansour, Mark, McPherson, John D., O’Brien, Catherine, Leighl, Natasha, Bedard, Philippe L., Fleshner, Neil, Liu, Geoffrey, Minden, Mark D., Gallinger, Steven, Goldenberg, Anna, Pugh, Trevor J., Hoffman, Michael M., Bratman, Scott V., Hung, Rayjean J., De Carvalho, Daniel D.

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Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease von Underwood, Benjamin R., Imarisio, Sara, Fleming, Angeleen, Rose, Claudia, Krishna, Gauri, Heard, Phoebe, Quick, Marie, Korolchuk, Viktor I., Renna, Maurizio, Sarkar, Sovan, García-Arencibia, Moisés, O'Kane, Cahir J., Murphy, Michael P., Rubinsztein, David C.

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Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease von Ravikumar, Brinda, Imarisio, Sara, Sarkar, Sovan, O'Kane, Cahir J, Rubinsztein, David C

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