Ophthalmic manifestations in a case of Wiedemann-Rautenstrauch syndrome von Barkley, Michael R., BAppSci(Optom), MBBS, O'Hagan, Stephen B., FRANZCO

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Epidemiology of open- and closed-globe trauma presenting to Cairns Base Hospital, Queensland von Smith, Andrew RE, O'Hagan, Stephen B, Gole, Glen A

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Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands von O'Hagan, Heather M., Wang, Wei, Sen, Subhojit, DeStefano Shields, Christina, Lee, Stella S., Zhang, Yang W., Clements, Eriko G., Cai, Yi, Van Neste, Leander, Easwaran, Hariharan, Casero, Robert A., Sears, Cynthia L., Baylin, Stephen B.

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Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations von Vaz, Michelle, Hwang, Stephen Y., Kagiampakis, Ioannis, Phallen, Jillian, Patil, Ashwini, O'Hagan, Heather M., Murphy, Lauren, Zahnow, Cynthia A., Gabrielson, Edward, Velculescu, Victor E., Easwaran, Hariharan P., Baylin, Stephen B.

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Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island von O'Hagan, Heather M, Mohammad, Helai P, Baylin, Stephen B

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The promise and peril of chemical probes von Arrowsmith, Cheryl H, Audia, James E, Austin, Christopher, Baell, Jonathan, Bennett, Jonathan, Blagg, Julian, Bountra, Chas, Brennan, Paul E, Brown, Peter J, Bunnage, Mark E, Buser-Doepner, Carolyn, Campbell, Robert M, Carter, Adrian J, Cohen, Philip, Copeland, Robert A, Cravatt, Ben, Dahlin, Jayme L, Dhanak, Dashyant, Edwards, Aled M, Frederiksen, Mathias, Frye, Stephen V, Gray, Nathanael, Grimshaw, Charles E, Hepworth, David, Howe, Trevor, Huber, Kilian V M, Jin, Jian, Knapp, Stefan, Kotz, Joanne D, Kruger, Ryan G, Lowe, Derek, Mader, Mary M, Marsden, Brian, Mueller-Fahrnow, Anke, Müller, Susanne, O'Hagan, Ronan C, Overington, John P, Owen, Dafydd R, Rosenberg, Saul H, Ross, Ruth, Roth, Bryan, Schapira, Matthieu, Schreiber, Stuart L, Shoichet, Brian, Sundström, Michael, Superti-Furga, Giulio, Taunton, Jack, Toledo-Sherman, Leticia, Walpole, Chris, Walters, Michael A, Willson, Timothy M, Workman, Paul, Young, Robert N, Zuercher, William J

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Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy von DeStefano Shields, Christina E, White, James R, Chung, Liam, Wenzel, Alyssa, Hicks, Jessica L, Tam, Ada J, Chan, June L, Dejea, Christine M, Fan, Hongni, Michel, John, Maiuri, Ashley R, Sriramkumar, Shruthi, Podicheti, Ram, Rusch, Douglas B, Wang, Hao, De Marzo, Angelo M, Besharati, Sepideh, Anders, Robert A, Baylin, Stephen B, O'Hagan, Heather M, Housseau, Franck, Sears, Cynthia L

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Examining temporal effects on cancer risk in the international nuclear workers’ study von Daniels, Robert D., Bertke, Stephen J., Richardson, David B., Cardis, Elisabeth, Gillies, Michael, O'Hagan, Jacqueline A., Haylock, Richard, Laurier, Dominique, Leuraud, Klervi, Moissonnier, Monika, Thierry‐Chef, Isabelle, Kesminiene, Ausrele, Schubauer‐Berigan, Mary K.

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Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage von Ding, Ning, Bonham, Emily M, Hannon, Brooke E, Amick, Thomas R, Baylin, Stephen B, O'Hagan, Heather M

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DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach von Khemchandani, Yash, O’Hagan, Stephen, Samanta, Soumitra, Swainston, Neil, Roberts, Timothy J., Bollegala, Danushka, Kell, Douglas B.

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Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines von Jeschke, Jana, O'Hagan, Heather M, Zhang, Wei, Vatapalli, Rajita, Calmon, Marilia Freitas, Danilova, Ludmila, Nelkenbrecher, Claudia, Van Neste, Leander, Bijsmans, Ingrid T G W, Van Engeland, Manon, Gabrielson, Edward, Schuebel, Kornel E, Winterpacht, Andreas, Baylin, Stephen B, Herman, James G, Ahuja, Nita

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Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization von Francica, Joseph R., Sheng, Zizhang, Zhang, Zhenhai, Nishimura, Yoshiaki, Shingai, Masashi, Ramesh, Akshaya, Keele, Brandon F., Schmidt, Stephen D., Flynn, Barbara J., Darko, Sam, Lynch, Rebecca M., Yamamoto, Takuya, Matus-Nicodemos, Rodrigo, Wolinsky, David, Nason, Martha, Valiante, Nicholas M., Malyala, Padma, De Gregorio, Ennio, Barnett, Susan W., Singh, Manmohan, O’Hagan, Derek T., Koup, Richard A., Mascola, John R., Martin, Malcolm A., Kepler, Thomas B., Douek, Daniel C., Shapiro, Lawrence, Seder, Robert A.

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Assessing Exposure to Violence in Urban Youth von Selner-O'Hagan, Mary Beth, Kindlon, Daniel J., Buka, Stephen L., Raudenbush, Stephen W., Earls, Felton J.

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Molecular phenotyping of a UK population: defining the human serum metabolome von Dunn, Warwick B., Lin, Wanchang, Broadhurst, David, Begley, Paul, Brown, Marie, Zelena, Eva, Vaughan, Andrew A., Halsall, Antony, Harding, Nadine, Knowles, Joshua D., Francis-McIntyre, Sue, Tseng, Andy, Ellis, David I., O’Hagan, Steve, Aarons, Gill, Benjamin, Boben, Chew-Graham, Stephen, Moseley, Carly, Potter, Paula, Winder, Catherine L., Potts, Catherine, Thornton, Paula, McWhirter, Catriona, Zubair, Mohammed, Pan, Martin, Burns, Alistair, Cruickshank, J. Kennedy, Jayson, Gordon C., Purandare, Nitin, Wu, Frederick C. W., Finn, Joe D., Haselden, John N., Nicholls, Andrew W., Wilson, Ian D., Goodacre, Royston, Kell, Douglas B.

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Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation von MOHAMMAD, Helai P, YI CAI, MCGARVEY, Kelly M, EASWARAN, Hariharan, VAN NESTE, Leander, OHM, Joyce E, O'HAGAN, Heather M, BAYLIN, Stephen B

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Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer von Calmon, Marilia Freitas, Jeschke, Jana, Zhang, Wei, Dhir, Mashaal, Siebenkäs, Cornelia, Herrera, Alexander, Tsai, Hsing-Chen, O'Hagan, Heather M, Pappou, Emmanouil P, Hooker, Craig M, Fu, Tao, Schuebel, Kornel E, Gabrielson, Edward, Rahal, Paula, Herman, James G, Baylin, Stephen B, Ahuja, Nita

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Epidemiological and Clinical Insights into Acinetobacter baumannii : A Six-Year Study on Age, Antibiotics, and Specimens von Almoghrabi, Yousef, Daghistani, Hussam, Niyazi, Hanouf A, Niyazi, Hatoon A, AbdulMajed, Hind, Juma, Noha A, Daffa, Noura, Helmi, Noof R, Al-Rabia, Mohammed W, Mokhtar, Jawahir A, Saleh, Bandar Hasan, Attallah, Dalya M, Matar, Maram, Shukri, Hani Ahmed, Moqaddam, Shahd A, Alamoudi, Sara, Alkuwaity, Khalil K, Abujamel, Turki, Sait, Ahmad M, Mufrrih, Mohammed, Al-Zahrani, Ibrahim A, O'hagan, Stephen, Ismail, Mazen A, Alharbi, Ohood S, Momin, Hattan Jamal, Abu, Ibrahim Mohammed, Alfadil, Abdelbagi, Ibrahem, Karem

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Abstract A18: Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage von Ding, Ning, Bonham, Emily M., Hannon, Brooke E., Baylin, Stephen B., O'Hagan, Heather M.

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A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites von Zhang, Shaowei, Sakuma, Michiyo, Deora, Girdhar S., Levy, Colin W., Klausing, Alex, Breda, Carlo, Read, Kevin D., Edlin, Chris D., Ross, Benjamin P., Wright Muelas, Marina, Day, Philip J., O’Hagan, Stephen, Kell, Douglas B., Schwarcz, Robert, Leys, David, Heyes, Derren J., Giorgini, Flaviano, Scrutton, Nigel S.

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Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial von Herrera, Carolina, Serwanga, Jennifer, Else, Laura, Limakatso, Lebina, Opoka, Daniel, Ssemata, Andrew S., Pillay, Azure-Dee, Namubiru, Patricia, Seiphetlo, Thabiso B., Odoch, Geoffrey, Mugaba, Susan, Seatlholo, Portia, Alieu, Amara, Penchala, Sujan Dilly, Muhumuza, Richard, Alinde, Berenice, Petkov, Stefan, O'Hagan, Kyle, Callebaut, Christian, Seeley, Janet, Weiss, Helen, Khoo, Saye, Chiodi, Francesca, Gray, Clive M., Kaleebu, Pontiano, Webb, Emily L., Martinson, Neil, Fox, Julie, Ahmed, Nadia, Alinde, Berenice, Alieu, Amara, Atujuna, Millicent, Awino, Esther, Bekker, Linda-Gail, Callebaut, Christian, Chiodi, Francesca, Chirenje, Mike, Dietrich, Janan, Dorfman, Jeffrey, Else, Laura, Fox, Julie, Gray, Clive, Hansen, Christian Holm, Herrera, Carolina, Hornschuh, Stefanie, Kakande, Ayoub, Kaleebu, Pontiano, Kelly, Charles, Khoo, Saye, Khunwane, Mamkiri, Lebina, Limaktso, Makhura, Joseph, Mangxilana, Nomvuyo, Martinson, Neil, Mugaba, Susan, Muhumuza, Richard, Kibengo, Freddie Mukasa, Mutonyi, Gertrude, Mungate, Lucia, Nabukeera, Winnie, Nagawa, Rehema, Nalubega, Phiona, Namubiru, Patricia, Nash, Stephen, Ndekezi, Denis, Nematadzira, Teacler, Nobula, Lumka, O'Hagan, Kyle, Odoch, Geoffrey, Opoka, Daniel, Penchala, Sujan Dilly, Petkov, Stefan, Pillay, Azure-Dee, Rooney, Jim, Rousseau, Elzette, Ruzagira, Eugene, Sango, Alison, Seatlholo, Ntombexolo, Seeley, Janet, Seiphetlo, Thabiso, Serwanga, Jennifer, Shattock, Robin, Ssemata, Andrew S., Stranix-Chibanda, Lynda, Tshabalala, Gugulethu, Webb, Emily, Weiss, Helen

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