Template‐Directed Copying of RNA by Non‐enzymatic Ligation von Zhou, Lijun, O'Flaherty, Derek K., Szostak, Jack W.

Volltext

Enhanced Nonenzymatic RNA Copying with 2‑Aminoimidazole Activated Nucleotides von Li, Li, Prywes, Noam, Tam, Chun Pong, O’Flaherty, Derek K, Lelyveld, Victor S, Izgu, Enver Cagri, Pal, Ayan, Szostak, Jack W

Volltext

Assembly of a Ribozyme Ligase from Short Oligomers by Nonenzymatic Ligation von Zhou, Lijun, O’Flaherty, Derek K, Szostak, Jack W

Volltext

Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3′-NP-DNA up to 25 Nucleotides Long Inside Model Protocells von O’Flaherty, Derek K, Zhou, Lijun, Szostak, Jack W

Volltext

The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis von Kim, Seohyun Chris, O’Flaherty, Derek K, Giurgiu, Constantin, Zhou, Lijun, Szostak, Jack W

Volltext

Copying of Mixed-Sequence RNA Templates inside Model Protocells von O’Flaherty, Derek K, Kamat, Neha P, Mirza, Fatima N, Li, Li, Prywes, Noam, Szostak, Jack W

Volltext

A Facile and General Tandem Oligonucleotide Synthesis Methodology for DNA and RNA von Saraya, Jagandeep S., O'Flaherty, Derek K.

Volltext

Thermally Driven Membrane Phase Transitions Enable Content Reshuffling in Primitive Cells von Rubio-Sánchez, Roger, O’Flaherty, Derek K, Wang, Anna, Coscia, Francesca, Petris, Gianluca, Di Michele, Lorenzo, Cicuta, Pietro, Bonfio, Claudia

Volltext

Front Cover: A Facile and General Tandem Oligonucleotide Synthesis Methodology for DNA and RNA (ChemBioChem 6/2024) von Saraya, Jagandeep S., O'Flaherty, Derek K.

Volltext

A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2′-Deoxynucleotides von Kim, Seohyun Chris, Zhou, Lijun, Zhang, Wen, O’Flaherty, Derek K, Rondo-Brovetto, Valeria, Szostak, Jack W

Volltext

Aqueous Compatible Post-Synthetic On-Column Conjugation of Nucleic Acids Using Amino-Modifiers von Saraya, Jagandeep S, Sammons, Scott R, O'Flaherty, Derek K

Volltext

Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA von Kim, Seohyun Chris, O’Flaherty, Derek K., Zhou, Lijun, Lelyveld, Victor S., Szostak, Jack W.

Volltext

Prebiotically Plausible “Patching” of RNA Backbone Cleavage through a 3′–5′ Pyrophosphate Linkage von Wright, Tom H, Giurgiu, Constantin, Zhang, Wen, Radakovic, Aleksandar, O’Flaherty, Derek K, Zhou, Lijun, Szostak, Jack W

Volltext

Non-enzymatic primer extension with strand displacement von Zhou, Lijun, Kim, Seohyun Chris, Ho, Katherine H, O'Flaherty, Derek K, Giurgiu, Constantin, Wright, Tom H, Szostak, Jack W

Volltext

A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension von Giurgiu, Constantin, Li, Li, O’Flaherty, Derek K, Tam, Chun Pong, Szostak, Jack W

Volltext

Unusual Base Pair between Two 2‑Thiouridines and Its Implication for Nonenzymatic RNA Copying von Ding, Dian, Fang, Ziyuan, Kim, Seohyun Chris, O’Flaherty, Derek K., Jia, Xiwen, Stone, Talbot B., Zhou, Lijun, Szostak, Jack W.

Volltext

siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′... von Akabane-Nakata, Masaaki, Erande, Namrata D, Kumar, Pawan, Degaonkar, Rohan, Gilbert, Jason A, Qin, June, Mendez, Martha, Woods, Lauren Blair, Jiang, Yongfeng, Janas, Maja M, O’Flaherty, Derek K, Zlatev, Ivan, Schlegel, Mark K, Matsuda, Shigeo, Egli, Martin, Manoharan, Muthiah

Volltext

Covalent capture of OGT's active site using engineered human-E. coli chimera and intrastrand DNA cross-links von Copp, William, O'Flaherty, Derek K, Wilds, Christopher J

Volltext

DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates von Lelyveld, Victor S, O'Flaherty, Derek K, Zhou, Lijun, Izgu, Enver Cagri, Szostak, Jack W

Volltext

Synthesis, Characterization, and Repair of a Flexible O(6) -2'-Deoxyguanosine-alkylene-O(6) -2'-deoxyguanosine Intrastrand Cross-Link von O'Flaherty, Derek K, Wilds, Christopher J

Volltext