Rethinking the role of clinical imaging von O'Connor, James Pb

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Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives von O'Connor, James PB, Dr, Jackson, Alan, Prof, Asselin, Marie-Claude, PhD, Buckley, David L, PhD, Parker, Geoff JM, Prof, Jayson, Gordon C, Prof

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Imaging Tumor Vascular Heterogeneity and Angiogenesis using Dynamic Contrast-Enhanced Magnetic Resonance Imaging von Jackson, Alan, O'Connor, James P B, Parker, Geoff J M, Jayson, Gordon C

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Oxygen Enhanced Optoacoustic Tomography (OE-OT) Reveals Vascular Dynamics in Murine Models of Prostate Cancer von Tomaszewski, Michal R, Gonzalez, Isabel Quiros, O'Connor, James Pb, Abeyakoon, Oshaani, Parker, Geoff Jm, Williams, Kaye J, Gilbert, Fiona J, Bohndiek, Sarah E

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Data‐driven mapping of hypoxia‐related tumor heterogeneity using DCE‐MRI and OE‐MRI von Featherstone, Adam K., O'Connor, James P.B., Little, Ross A., Watson, Yvonne, Cheung, Sue, Babur, Muhammad, Williams, Kaye J., Matthews, Julian C., Parker, Geoff J.M.

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Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma von Linnik, Inna V., Scott, Marietta L. J., Holliday, Katherine F., Woodhouse, Neil, Waterton, John C., O'Connor, James P. B., Barjat, Hervé, Liess, Carsten, Ulloa, Jose, Young, Helen, Dive, Caroline, Hodgkinson, Cassandra L., Ward, Tim, Roberts, Darren, Mills, Samantha J., Thompson, Gerard, Buonaccorsi, Giovanni A., Cheung, Susan, Jackson, Alan, Naish, Josephine H., Parker, Geoff J.M.

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Translating imaging biomarkers into clinical practice von O'Connor, James PB

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Apparent diffusion coefficient is highly reproducible on preclinical imaging systems: Evidence from a seven-center multivendor study von Doblas, Sabrina, Almeida, Gilberto S., Blé, François-Xavier, Garteiser, Philippe, Hoff, Benjamin A., McIntyre, Dominick J.O., Wachsmuth, Lydia, Chenevert, Thomas L., Faber, Cornelius, Griffiths, John R., Jacobs, Andreas H., Morris, David M., O'Connor, James P.B., Robinson, Simon P., Van Beers, Bernard E., Waterton, John C.

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Detecting gas-induced vasomotor changes via blood oxygenation level-dependent contrast in healthy breast parenchyma and breast carcinoma von Wallace, Tess E., Patterson, Andrew J., Abeyakoon, Oshaani, Bedair, Reem, Manavaki, Roido, McLean, Mary A., O'Connor, James P.B., Graves, Martin J., Gilbert, Fiona J.

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Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models von O'Connor, James P B, Boult, Jessica K R, Jamin, Yann, Babur, Muhammad, Finegan, Katherine G, Williams, Kaye J, Little, Ross A, Jackson, Alan, Parker, Geoff J M, Reynolds, Andrew R, Waterton, John C, Robinson, Simon P

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Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer von Skwarski, Michael, McGowan, Daniel R., Belcher, Elizabeth, Di Chiara, Francesco, Stavroulias, Dionisios, McCole, Mark, Derham, Jennifer L., Chu, Kwun-Ye, Teoh, Eugene, Chauhan, Jagat, O'Reilly, Dawn, Harris, Benjamin H. L., Macklin, Philip S., Bull, Joshua A., Green, Marcus, Rodriguez-Berriguete, Gonzalo, Prevo, Remko, Folkes, Lisa K., Campo, Leticia, Ferencz, Petra, Croal, Paula L., Flight, Helen, Qi, Cathy, Holmes, Jane, O'Connor, James P. B., Gleeson, Fergus, McKenna, W. Gillies, Harris, Adrian L., Bulte, Daniel, Buffa, Francesca M., Macpherson, Ruth E., Higgins, Geoff S.

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Mixed-effects modeling of clinical DCE-MRI data: Application to colorectal liver metastases treated with bevacizumab von Ferl, Gregory Z., O'Connor, James P.B., Parker, Geoffrey J.M., Carano, Richard A.D., Acharya, Shiv J., Jayson, Gordon C., Port, Ruediger E.

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Indexed distribution analysis for improved significance testing of spatially heterogeneous parameter maps: Application to dynamic contrast-enhanced MRI biomarkers von Rose, Chris J., O'Connor, James P. B., Cootes, Tim F., Taylor, Chris J., Jayson, Gordon C., Parker, Geoff J. M., Waterton, John C.

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Tumour enhancing fraction (EnF) in glioma: relationship to tumour grade von Mills, Samantha J., Soh, Calvin, O’Connor, James P. B., Rose, Chris J., Buonaccorsi, Giovanni A., Cheung, Susan, Zhao, Sha, Parker, Geoff J. M., Jackson, Alan

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Comparison of the Performance of Tracer Kinetic Model-Driven Registration for Dynamic Contrast Enhanced MRI Using Different Models of Contrast Enhancement von Buonaccorsi, Giovanni A., Roberts, Caleb, Cheung, Sue, Watson, Yvonne, O’Connor, James P.B., Davies, Karen, Jackson, Alan, Jayson, Gordon C., Parker, Geoff J.M.

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Oxygen-induced changes in longitudinal relaxation times in skeletal muscle von McGrath, Deirdre M, Naish, Josephine H, O'Connor, James P.B, Hutchinson, Charles E, Waterton, John C, Taylor, Chris J, Parker, Geoffrey J.M

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Feasibility of dynamic T2-based oxygen-enhanced lung MRI at 3T von Kim, Mina, Naish, Josephine H, Needleman, Sarah H, Tibiletti, Marta, Taylor, Yohn, O'Connor, James PB, Parker, Geoff JM

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Independent component analysis (ICA) applied to dynamic oxygen-enhanced MRI (OE-MRI) for robust functional lung imaging at 3 T von Needleman, Sarah H, Kim, Mina, McClelland, Jamie R, Naish, Josephine H, Tibiletti, Marta, O'Connor, James PB, Parker, Geoff JM

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Measuring repeatability of dynamic contrast-enhanced MRI biomarkers improves evaluation of biological response to radiotherapy in lung cancer von Sridharan, Nivetha, Salem, Ahmed, Little, Ross A, Tariq, Maira, Cheung, Susan, Dubec, Michael J, Faivre-Finn, Corinne, Parker, Geoffrey JM, Porta, Nuria, O'Connor, James PB

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Clinical translation of quantitative magnetic resonance imaging biomarkers – An overview and gap analysis of current practice von Hubbard Cristinacce, Penny L, Keaveney, Sam, Aboagye, Eric O, Hall, Matt G, Little, Ross A, O'Connor, James PB, Parker, Geoff JM, Waterton, John C, Winfield, Jessica M, Jauregui-Osoro, Maite

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