Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer von Zhang, Lei, Li, Ziyi, Skrzypczynska, Katarzyna M., Fang, Qiao, Zhang, Wei, O’Brien, Sarah A., He, Yao, Wang, Lynn, Zhang, Qiming, Kim, Aeryon, Gao, Ranran, Orf, Jessica, Wang, Tao, Sawant, Deepali, Kang, Jiajinlong, Bhatt, Dev, Lu, Daniel, Li, Chi-Ming, Rapaport, Aaron S., Perez, Kristy, Ye, Yingjiang, Wang, Shan, Hu, Xueda, Ren, Xianwen, Ouyang, Wenjun, Shen, Zhanlong, Egen, Jackson G., Zhang, Zemin, Yu, Xin

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End-of-life planning with frail patients attending general practice: an exploratory prospective cross-sectional study von Dunphy, Eoin J, Conlon, Sarah C, O'Brien, Sarah A, Loughrey, Emer, O'Shea, Brendan J

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Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment von O’Brien, Sarah A., Orf, Jessica, Skrzypczynska, Katarzyna M., Tan, Hong, Kim, Jennie, DeVoss, Jason, Belmontes, Brian, Egen, Jackson G.

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Spontaneous Differentiation of T Follicular Helper Cells in LATY136F Mutant Mice von O'Brien, Sarah A, Zhu, Minghua, Zhang, Weiguo

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Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity von Kim, Jennie C., Liu, Xian, Fitzgerald, Karen, Eng, Jason S., Orf, Jessica, O’Brien, Sarah A., Belmontes, Brian, Casbon, Amy-Jo, Novitskiy, Sergey V., Tarbell, Kristin V., DeVoss, Jason, Egen, Jackson G.

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Phospholipase D in TCR-Mediated Signaling and T Cell Activation von Zhu, Minghua, Foreman, Daniel P, O'Brien, Sarah A, Jin, Yuefei, Zhang, Weiguo

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The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity von O'Brien, Sarah A, Zhu, Minghua, Zhang, Weiguo

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Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function von Zhu, Minghua, Zou, Jianwei, Li, Tieshi, O'Brien, Sarah A, Zhang, Yao, Ogden, Sarah, Zhang, Weiguo

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Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response von Norgard, Robert J, Budhani, Pratha, O'Brien, Sarah A, Xia, Youli, Egan, Jessica N, Flynn, Brianna, Tagore, Joshua R, Seco, Joseph, Peet, Gregory W, Mikucka, Ania, Wasti, Ruby, Chan, Li-Chuan, Hinkel, Melanie, Martinez-Morilla, Sandra, Pignatelli, Jeanine, Trapani, Francesca, Corse, Emily, Feng, Di, Kostyrko, Kaja, Hofmann, Marco H, Liu, Kang, Kashyap, Abhishek

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Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice von Tam, Clarence C, Rodrigues, Laura C, Viviani, Laura, Dodds, Julie P, Evans, Meirion R, Hunter, Paul R, Gray, Jim J, Letley, Louise H, Rait, Greta, Tompkins, David S, O'Brien, Sarah J

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Patients' perspectives on providing a stool sample to their GP: a qualitative study von Lecky, Donna M, Hawking, Meredith K D, McNulty, Cliodna A M

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Sertraline for anxiety in adults with a diagnosis of autism (STRATA): study protocol for a pragmatic, multicentre, double-blind, placebo-controlled randomised controlled trial von Rai, Dheeraj, Webb, Doug, Lewis, Amanda, Cotton, Leonora, Norris, Jade Eloise, Alexander, Regi, Baldwin, David S, Brugha, Traolach, Cochrane, Madeleine, Del Piccolo, Maria Chiara, Glasson, Emma J, Hatch, Katherine K, Kessler, David, Langdon, Peter E, Leonard, Helen, MacNeill, Stephanie J, Mills, Nicola, Morales, Maximiliano Vazquez, Morgan, Zoe, Mukherjee, Raja, Realpe, Alba X, Russell, Ailsa, Starkstein, Sergio, Taylor, Jodi, Turner, Nicholas, Thorn, Joanna, Welch, Jack, Wiles, Nicola

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Changes in Causes of Acute Gastroenteritis in the United Kingdom Over 15 Years: Microbiologic Findings From 2 Prospective, Population-Based Studies of Infectious Intestinal Disease von Tam, Clarence C., O'Brien, Sarah J., Tompkins, David S., Bolton, Frederick J., Berry, Lisa, Dodds, Julie, Choudhury, Dalia, Halstead, Fenella, Iturriza-Gómara, Miren, Mather, Katherine, Rait, Greta, Ridge, Alan, Rodrigues, Laura C., Wain, John, Wood, Bernard, Gray, James J.

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Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DO... von Goldenberg, Neil A, Kittelson, John M, Abshire, Thomas C, Bonaca, Marc, Casella, James F, Dale, Rita A, Halperin, Jonathan L, Hamblin, Frances, Kessler, Craig M, Manco-Johnson, Marilyn J, Sidonio, Robert F, Spyropoulos, Alex C, Steg, P. Gabriel, Turpie, Alexander G. G, Schulman, Sam

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Impact of Biopsychosocial Factors on Chronic Pain in Persons With Myotonic and Facioscapulohumeral Muscular Dystrophy von Miró, Jordi, Raichle, Katherine A., Carter, Gregory T., O'Brien, Sarah A., Abresch, Richard T., McDonald, Craig M., Jensen, Mark P.

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Abstract 2803: CSF-1 receptor-mediated macrophage depletion can induce immunomodulatory resistance mechanisms in murine tumor models von O'Brien, Sarah A., Skrzypczynska, Katarzyna, Orf, Jessica, Belmontes, Brian, Tan, Hong, Lu, Daniel, Driver, Ian, Egen, Jackson

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Phospholipase D in T cell receptor-mediated signaling and T cell activation von Zhu, Minghua, Foreman, Daniel, O'Brien, Sarah A., Jin, Yuefei, Zhang, Weiguo

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Abstract A71: Resistance mechanisms limiting the immunostimulatory and antitumor activity of anti-CSF-1 receptor-mediated macrophage depletion von Skrzypczynska, Katarzyna M., O'Brien, Sarah A., Belmontes, Brian, Tan, Hong, Orf, Jessica, Lu, Daniel, Driver, Ian, Egen, Jackson G.

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Illustrated State‐of‐the‐Art Capsules of the ISTH 2019 Congress in Melbourne, Australia von Ward, Christopher M., Andrews, Robert K., Barco, Stefano, Battinelli, E.M., Boilard, Eric, Bos, Mettine H.A., Chicanne, G., Chuansumrit, Ampaiwan, Conway, Edward M., Curry, N., Cutler, Daniel, Danese, Elisa, De Meyer, Simon F., Del Rio, Jose M., Despotovic, Jenny, Di Paola, Jorge, Eikelboom, John, Emsley, Jonas, Eto, Koji, Fijnvandraat, Karin, Flaumenhaft, Robert, Flick, Matthew, Fuchs, Tobias A., Gomez, Keith, Goto, Shinya, Hamilton, Justin R., Hitchcock, Ian S., Jenne, Craig N., Johnsen, Jill M., Ju, Lining A., Le Gal, Grégoire, Levade, M., Lip, Gregory Y.H., Luyendyk, Jim, Maas, Coen, Magnusson, Maria, Mangin, Pierre, Mast, Alan, McLintock, Claire, Miranda, Sébastien, Nathwani, Amit, Ni, Heyu, Áinle, Fionnuala N., Nilsson, Susie, Ny, Tor, O’Brien, Sarah H., O’Donnell, James S., Payrastre, B., Peter, Karlheinz, Rak, Janusz, Randi, Anna M., Rauova, Lubica, Reinhardt, Christoph, Rodger, Marc, Rondina, Matthew, Schreiber, Karen, Severin, S., Shima, Midori, Spyropoulos, Alex, Stanworth, S.J., Suzuki‐Inoue, Katsue, Thomas, Moumneh, Tsukiji, Nagaharu, Urano, Tetsumei, Valet, C., Vanhoorelbeke, Karen, Verhamme, Peter, Weitz, Jeffrey, Wolberg, Alisa, Zentner, Dominica, Zhu, Cheng

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The Importance of Interleukin-6 in the Development of LAT-mediated Autoimmunity von O’Brien, Sarah A., Zhu, Minghua, Zhang, Weiguo

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