A Phase 1, Open-Label, Dose Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of a first in class Pol1 inhibitor (CX-5461) in Patients with Advanced Haematologic Malign... von Khot, A, Brajanovski, N, Cameron, D, Hein, N, McArthur, G.A, Lim, J.K.C, O'Brien, S.E, Ryckman, D, Yu, G.I, Link, E, Donohoe, C, Snowden, A, Hannan, R, Harrison, S.J

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Targeted scan of fifteen regions for nonsyndromic cleft lip and palate in Filipino families von Schultz, R.E., Cooper, M.E., Daack-Hirsch, S., Shi, M., Nepomucena, B., Graf, K.A., O'Brien, E.K., O'Brien, S.E., Marazita, M.L., Murray, J.C.

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414 Clinical pharmacokinetics and pharmacodynamics of CX-4945, a novel inhibitor of protein kinase CK2: Interim report from the phase 1 clinical trial von Padgett, C.S, Lim, J.K.C, Marschke, R.F, Northfelt, D.W, Andreopoulou, E, Hoff, D.D. Von, Anderes, K, Ryckman, D.M, Chen, T.K, O'Brien, S.E

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70: Proffered Paper: Inhibition of RNA Polymerase I transcription by CX-5461 as a completely new approach to treat highly refractory haematological malignancies von Hannan, R, Hein, N, O’Brien, S.E, Drygin, D, Cullinane, C, Matthews, G, Johnstone, R.W, Pearson, R.B, McArthur, G, Harrison, S

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Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate von Jezewski, P A, Vieira, A R, Nishimura, C, Ludwig, B, Johnson, M, O’Brien, S E, Daack-Hirsch, S, Schultz, R E, Weber, A, Nepomucena, B, Romitti, P A, Christensen, K, Orioli, I M, Castilla, E E, Machida, J, Natsume, N, Murray, J C

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Diagnostic Criteria for Vascular Cognitive Disorders: A VASCOG Statement von Sachdev, Perminder, Kalaria, Raj, O’Brien, John, Skoog, Ingmar, Alladi, Suvarna, Black, Sandra E, Blacker, Deborah, Blazer, Dan G, Chen, Christopher, Chui, Helena, Ganguli, Mary, Jellinger, Kurt, Jeste, Dilip V, Pasquier, Florence, Paulsen, Jane, Prins, Niels, Rockwood, Kenneth, Roman, Gustavo, Scheltens, Philip

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Mechanical failure begins preferentially near resorption cavities in human vertebral cancellous bone under compression von Slyfield, C.R, Tkachenko, E.V, Fischer, S.E, Ehlert, K.M, Yi, I.H, Jekir, M.G, O'Brien, R.G, Keaveny, T.M, Hernandez, C.J

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De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability von McCarthy, S E, Gillis, J, Kramer, M, Lihm, J, Yoon, S, Berstein, Y, Mistry, M, Pavlidis, P, Solomon, R, Ghiban, E, Antoniou, E, Kelleher, E, O'Brien, C, Donohoe, G, Gill, M, Morris, D W, McCombie, W R, Corvin, A

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Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000) von Silverman, L B, Stevenson, K E, O'Brien, J E, Asselin, B L, Barr, R D, Clavell, L, Cole, P D, Kelly, K M, Laverdiere, C, Michon, B, Schorin, M A, Schwartz, C L, O'Holleran, E W, Neuberg, D S, Cohen, H J, Sallan, S E

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Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts von Landrigan, Christopher P, Rahman, Shadab A, Sullivan, Jason P, Vittinghoff, Eric, Barger, Laura K, Sanderson, Amy L, Wright, Kenneth P, O’Brien, Conor S, Qadri, Salim, St. Hilaire, Melissa A, Halbower, Ann C, Segar, Jeffrey L, McGuire, John K, Vitiello, Michael V, de la Iglesia, Horacio O, Poynter, Sue E, Yu, Pearl L, Zee, Phyllis C, Lockley, Steven W, Stone, Katie L, Czeisler, Charles A

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Development of a Bridge Weigh-in-Motion Sensor: Performance Comparison Using Fiber Optic and Electric Resistance Strain Sensor Systems von Lydon, M., Taylor, S.E., Robinson, D., Callender, P., Doherty, C., Grattan, S.K.T., O'Brien, E.J.

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Discovery of the nearby long, soft GRB 100316D with an associated supernova von Starling, R. L. C., Wiersema, K., Levan, A. J., Sakamoto, T., Bersier, D., Goldoni, P., Oates, S. R., Rowlinson, A., Campana, S., Sollerman, J., Tanvir, N. R., Malesani, D., Fynbo, J. P. U., Covino, S., D'Avanzo, P., O'Brien, P. T., Page, K. L., Osborne, J. P., Vergani, S. D., Barthelmy, S., Burrows, D. N., Cano, Z., Curran, P. A., De Pasquale, M., D'Elia, V., Evans, P. A., Flores, H., Fruchter, A. S., Garnavich, P., Gehrels, N., Gorosabel, J., Hjorth, J., Holland, S. T., van der Horst, A. J., Hurkett, C. P., Jakobsson, P., Kamble, A. P., Kouveliotou, C., Kuin, N. P. M., Kaper, L., Mazzali, P. A., Nugent, P. E., Pian, E., Stamatikos, M., Thöne, C. C., Woosley, S. E.

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Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly von McNeil, John J, Wolfe, Rory, Woods, Robyn L, Tonkin, Andrew M, Donnan, Geoffrey A, Nelson, Mark R, Reid, Christopher M, Lockery, Jessica E, Kirpach, Brenda, Storey, Elsdon, Shah, Raj C, Williamson, Jeff D, Margolis, Karen L, Ernst, Michael E, Abhayaratna, Walter P, Stocks, Nigel, Fitzgerald, Sharyn M, Orchard, Suzanne G, Trevaks, Ruth E, Beilin, Lawrence J, Johnston, Colin I, Ryan, Joanne, Radziszewska, Barbara, Jelinek, Michael, Malik, Mobin, Eaton, Charles B, Brauer, Donna, Cloud, Geoff, Wood, Erica M, Mahady, Suzanne E, Satterfield, Suzanne, Grimm, Richard, Murray, Anne M

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Associations of obesity with triglycerides and C-reactive protein are attenuated in adults with high red blood cell eicosapentaenoic and docosahexaenoic acids von Makhoul, Z, Kristal, A R, Gulati, R, Luick, B, Bersamin, A, O'Brien, D, Hopkins, S E, Stephensen, C B, Stanhope, K L, Havel, P J, Boyer, B

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Development and delivery of an exercise intervention for rheumatoid arthritis: Strengthening and stretching for rheumatoid arthritis of the hand (SARAH) trial von Heine, P.J, Williams, M.A, Williamson, E, Bridle, C, Adams, J, O’Brien, A, Evans, D, Lamb, S.E

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Mortality, perioperative complications and surgical timelines in hip fracture patients: Comparison of the Spanish with the non-Spanish Cohort of the HIP ATTACK-1 trial von Guerra-Farfan, Ernesto, Bhandari, Mohit, Nuñez, Jorge H., Mestre-Torres, Jaume, Tomas-Hernandez, Jordi, Dealbert, Alfred, Vincent, Jessica, Cornu, Olivier, Clinckaert, Carol, Tandon, Vikas, Gauthier, Leslie P, Avram, Victoria R.A., Deheshi, Benjamin, Wong, Steven C.W., Quraishi, Faraaz A, Lawendy, Abdel-Rahman, Vasarhelyi, Edward, Bartley, Debra, Jenkinson, Richard J, Tuazon, Ravianne, Ravi, Bheeshma, Jaeger, Melanie T., McIlquham, Katie, Smith, Crystal A., Oyenubi, Ademilola N., Whelan, Daniel B., Atrey, Amit, Puskas, David, Greene, James, Sadoughi, Mehdi, White, Neil J., Duncan, Andrew W., Liu, Yang, Shan, Lei, Wu, Anshi, Muñoz, Juan M., Louboutin, Lucie, Beroud, Sebastien, Fayet, Jean Marie, Georgekutty, A.M., Barnawal, Satish P., Menon, Jagdish, M, Niranjan, Jawali, Abhijit, Kp, Mary, Sharma, Vijay, Tripathy, Vijaylaxmi, Menon, Prem H., Dhillon, Mandeep S., Colnaghi, Eleonora, Salini, Vincenzo, Placella, Giacomo, Piccirillo, Fabio, Khor, H.M., Loh, P.S., Chaw, Sook Hui, Ngim, Joanne H.L., Kleinlugtenbelt, Ydo V., Flikweert, Elvira R., Brokelman, Roy B.G., Horst, Maarten R., Umer, Masood, Wahab, Hussain, Khan, Abdus S., Ślęczka, Paweł, Satora, Wojciech, Firth, Gregory B., Fourtounas, Maria, Iqbal, Muhammad N., Campbell, Ryan J., Maluleke, Matimba L., Nhlapo, Lerato, Chetty, Sean, Guerra-Farfan, Ernesto, Garcia-Sanchez, Yaiza, Teixidor-Serra, Jordi, Andres-Peiro, Jose-Vicente, Mestre-Torres, Jaume, Posada, M.A. Gonzalez, Sanchez-Raya, Judith, Balaguer-Castro, Mariano, Jornet-Gibert, Montsant, Ricol, Laura, Martínez-Sañudo, Luis, Feijoo-Massó, Carlos, Sianes-Gallén, Mònica, Dealbert, Alfred, Ivanov, Alexia, Anaya, Rafael, Baños, Victoria, Cano, Juan R, Pengrung, Nachapan, Yingchoncharoen, Teerapat, Thayaparan, Surendini, Haire, Kevin, Mayor, Amy S.E., O'Sullivan, Susan, McClellan, Robert T, Joseph, Katherine, Phieffer, Laura S

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The association between the maternal diet and the gut microbiome: a systematic review von Maher, S.E., O’Brien, E.C., McAuliffe, F.M.

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Genetic variation in gonadal impairment in female survivors of childhood cancer: a PanCareLIFE study protocol von van der Kooi, Anne-Lotte L F, Clemens, Eva, Broer, Linda, Zolk, Oliver, Byrne, Julianne, Campbell, Helen, van den Berg, Marleen, Berger, Claire, Calaminus, Gabriele, Dirksen, Uta, Winther, Jeanette Falck, Fosså, Sophie D, Grabow, Desiree, Haupt, Riccardo, Kaiser, Melanie, Kepak, Tomas, Kremer, Leontien, Kruseova, Jarmila, Modan-Moses, Dalit, Ranft, Andreas, Spix, Claudia, Kaatsch, Peter, Laven, Joop S E, van Dulmen-den Broeder, Eline, Uitterlinden, André G, van den Heuvel-Eibrink, Marry M

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Isotopic estimates of sugar intake are related to chronic disease risk factors but not obesity in an Alaska native (Yup’ik) study population von Nash, S H, Kristal, A R, Bersamin, A, Choy, K, Hopkins, S E, Stanhope, K L, Havel, P J, Boyer, B B, O'Brien, D M

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Investigating a cluster of vulvar cancer in young women: a cross-sectional study of genital human papillomavirus prevalence von Rumbold, Alice R, Tan, Sarah E, Condon, John R, Taylor-Thomson, Debbie, Nickels, Maria, Tabrizi, Sepehr N, Davy, Margaret L J, O'Brien, Margaret M, Connors, Christine M, Zardawi, Ibrahim, Stankovich, Jim, Garland, Suzanne M

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