The distribution of fitness effects during adaptive walks using a simple genetic network von O'Brien, Nicholas L V, Holland, Barbara, Engelstädter, Jan, Ortiz-Barrientos, Daniel

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Digest: Stable phenotypes, fluid genotypes: how stochasticity impacts network evolution and speciation von James, Maddie E., O'Brien, Nicholas L. V., Bukkuri, Anuraag

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Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in ATM , BRCA1 , BRCA2 , CHEK2 , and PALB2 von Yadav, Siddhartha, Boddicker, Nicholas J, Na, Jie, Polley, Eric C, Hu, Chunling, Hart, Steven N, Gnanaolivu, Rohan D, Larson, Nicole, Holtegaard, Susan, Huang, Huaizhi, Dunn, Carolyn A, Teras, Lauren R, Patel, Alpa V, Lacey, James V, Neuhausen, Susan L, Martinez, Elena, Haiman, Christopher, Chen, Fei, Ruddy, Kathryn J, Olson, Janet E, John, Esther M, Kurian, Allison W, Sandler, Dale P, O'Brien, Katie M, Taylor, Jack A, Weinberg, Clarice R, Anton-Culver, Hoda, Ziogas, Argyrios, Zirpoli, Gary, Goldgar, David E, Palmer, Julie R, Domchek, Susan M, Weitzel, Jeffrey N, Nathanson, Katherine L, Kraft, Peter, Couch, Fergus J

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The Comprehensive Antibiotic Resistance Database von MCARTHUR, Andrew G, WAGLECHNER, Nicholas, KALAN, Lindsay, KING, Andrew M, KOTEVA, Kalinka, MORAR, Mariya, MULVEY, Michael R, O'BRIEN, Jonathan S, PAWLOWSKI, Andrew C, PIDDOCK, Laura J. V, SPANOGIANNOPOULOS, Peter, SUTHERLAND, Arlene D, NIZAM, Fazmin, TANG, Irene, TAYLOR, Patricia L, THAKER, Maulik, WENLIANG WANG, YAN, Marie, YU, Tennison, WRIGHT, Gerard D, YAN, Austin, AZAD, Marisa A, BAYLAY, Alison J, BHULLAR, Kirandeep, CANOVA, Marc J, DE PASCALE, Gianfranco, EJIM, Linda

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Assessment of Safety of a Fully Implanted Endovascular Brain-Computer Interface for Severe Paralysis in 4 Patients: The Stentrode With Thought-Controlled Digital Switch (SWITCH) St... von Mitchell, Peter, Lee, Sarah C. M, Yoo, Peter E, Morokoff, Andrew, Sharma, Rahul P, Williams, Daryl L, MacIsaac, Christopher, Howard, Mark E, Irving, Lou, Vrljic, Ivan, Williams, Cameron, Bush, Steven, Balabanski, Anna H, Drummond, Katharine J, Desmond, Patricia, Weber, Douglas, Denison, Timothy, Mathers, Susan, O’Brien, Terence J, Mocco, J, Grayden, David B, Liebeskind, David S, Opie, Nicholas L, Oxley, Thomas J, Campbell, Bruce C. V

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Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss von Fedoriw, Andrew, Rajapurkar, Satyajit R., O'Brien, Shane, Gerhart, Sarah V., Mitchell, Lorna H., Adams, Nicholas D., Rioux, Nathalie, Lingaraj, Trupti, Ribich, Scott A., Pappalardi, Melissa B., Shah, Niyant, Laraio, Jenny, Liu, Yan, Butticello, Michael, Carpenter, Chris L., Creasy, Caretha, Korenchuk, Susan, McCabe, Michael T., McHugh, Charles F., Nagarajan, Raman, Wagner, Craig, Zappacosta, Francesca, Annan, Roland, Concha, Nestor O., Thomas, Roberta A., Hart, Timothy K., Smith, Jesse J., Copeland, Robert A., Moyer, Mikel P., Campbell, John, Stickland, Kim, Mills, James, Jacques-O’Hagan, Suzanne, Allain, Christina, Johnston, Danielle, Raimondi, Alejandra, Porter Scott, Margaret, Waters, Nigel, Swinger, Kerren, Boriack-Sjodin, Ann, Riera, Tom, Shapiro, Gideon, Chesworth, Richard, Prinjha, Rabinder K., Kruger, Ryan G., Barbash, Olena, Mohammad, Helai P.

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Wastewater-based epidemiology biomarkers: Past, present and future von Choi, Phil M., Tscharke, Ben J., Donner, Erica, O'Brien, Jake W., Grant, Sharon C., Kaserzon, Sarit L., Mackie, Rachel, O'Malley, Elissa, Crosbie, Nicholas D., Thomas, Kevin V., Mueller, Jochen F.

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Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study von O'Brien, Katherine L., Baggett, Henry C., Brooks, W. Abdullah, Feikin, Daniel R., Hammitt, Laura L., Higdon, Melissa M., Howie, Stephen R.C., Deloria Knoll, Maria, Kotloff, Karen L., Levine, Orin S., Madhi, Shabir A., Murdoch, David R., Prosperi, Christine, Scott, J. Anthony G., Shi, Qiyuan, Thea, Donald M., Wu, Zhenke, Zeger, Scott L., Adrian, Peter V., Akarasewi, Pasakorn, Anderson, Trevor P., Antonio, Martin, Awori, Juliet O., Baillie, Vicky L., Bunthi, Charatdao, Chipeta, James, Chisti, Mohammod Jobayer, Crawley, Jane, DeLuca, Andrea N., Driscoll, Amanda J., Ebruke, Bernard E., Endtz, Hubert P., Fancourt, Nicholas, Fu, Wei, Goswami, Doli, Groome, Michelle J., Haddix, Meredith, Hossain, Lokman, Jahan, Yasmin, Kagucia, E. Wangeci, Kamau, Alice, Karron, Ruth A., Kazungu, Sidi, Kourouma, Nana, Kuwanda, Locadiah, Kwenda, Geoffrey, Li, Mengying, Machuka, Eunice M., Mackenzie, Grant, Mahomed, Nasreen, Maloney, Susan A., McLellan, Jessica L., Mitchell, Joanne L., Moore, David P., Morpeth, Susan C., Mudau, Azwifarwi, Mwananyanda, Lawrence, Mwansa, James, Silaba Ominde, Micah, Onwuchekwa, Uma, Park, Daniel E., Rhodes, Julia, Sawatwong, Pongpun, Seidenberg, Phil, Shamsul, Arifin, Simões, Eric A.F., Sissoko, Seydou, Wa Somwe, Somwe, Sow, Samba O., Sylla, Mamadou, Tamboura, Boubou, Tapia, Milagritos D., Thamthitiwat, Somsak, Toure, Aliou, Watson, Nora L., Zaman, Khalequ, Zaman, Syed M.A.

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A Population-Based Study of Genes Previously Implicated in Breast Cancer von Hu, Chunling, Hart, Steven N, Gnanaolivu, Rohan, Huang, Hongyan, Lee, Kun Y, Na, Jie, Gao, Chi, Lilyquist, Jenna, Yadav, Siddhartha, Boddicker, Nicholas J, Samara, Raed, Klebba, Josh, Ambrosone, Christine B, Anton-Culver, Hoda, Auer, Paul, Bandera, Elisa V, Bernstein, Leslie, Bertrand, Kimberly A, Burnside, Elizabeth S, Carter, Brian D, Eliassen, Heather, Gapstur, Susan M, Gaudet, Mia, Haiman, Christopher, Hodge, James M, Hunter, David J, Jacobs, Eric J, John, Esther M, Kooperberg, Charles, Kurian, Allison W, Le Marchand, Loic, Lindstroem, Sara, Lindstrom, Tricia, Ma, Huiyan, Neuhausen, Susan, Newcomb, Polly A, O’Brien, Katie M, Olson, Janet E, Ong, Irene M, Pal, Tuya, Palmer, Julie R, Patel, Alpa V, Reid, Sonya, Rosenberg, Lynn, Sandler, Dale P, Scott, Christopher, Tamimi, Rulla, Taylor, Jack A, Trentham-Dietz, Amy, Vachon, Celine M, Weinberg, Clarice, Yao, Song, Ziogas, Argyrios, Weitzel, Jeffrey N, Goldgar, David E, Domchek, Susan M, Nathanson, Katherine L, Kraft, Peter, Polley, Eric C, Couch, Fergus J

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High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial von Shah, Anoop S V, Anand, Atul, Strachan, Fiona E, Ferry, Amy V, Lee, Kuan Ken, Chapman, Andrew R, Sandeman, Dennis, Stables, Catherine L, Adamson, Philip D, Andrews, Jack P M, Anwar, Mohamed S, Hung, John, Moss, Alistair J, O'Brien, Rachel, Berry, Colin, Findlay, Iain, Walker, Simon, Cruickshank, Anne, Reid, Alan, Gray, Alasdair, Collinson, Paul O, Apple, Fred S, McAllister, David A, Maguire, Donogh, Fox, Keith A A, Newby, David E, Tuck, Christopher, Harkess, Ronald, Parker, Richard A, Keerie, Catriona, Weir, Christopher J, Mills, Nicholas L, Marshall, Lucy, Stewart, Stacey D, Fujisawa, Takeshi, Vallejos, Catalina A, Tsanas, Athanasios, Hautvast, Mischa, McPherson, Jean, McKinlay, Lynn, Malo, Jonathan, Fischbacher, Colin M, Croal, Bernard L, Leslie, Stephen J, Walker, Allan, Wackett, Tony, Armstrong, Roma, Stirling, Laura, MacDonald, Claire, Sadat, Imran, Finlay, Frank, Charles, Heather, Linksted, Pamela, Young, Stephen, Alexander, Bill, Duncan, Chris

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Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score von Gao, Chi, Polley, Eric C., Hart, Steven N., Huang, Hongyan, Hu, Chunling, Gnanaolivu, Rohan, Lilyquist, Jenna, Boddicker, Nicholas J., Na, Jie, Ambrosone, Christine B., Auer, Paul L., Bernstein, Leslie, Burnside, Elizabeth S., Eliassen, A. Heather, Gaudet, Mia M., Haiman, Christopher, Hunter, David J., Jacobs, Eric J., John, Esther M., Lindstrom, Sara, Ma, Huiyan, Neuhausen, Susan L., Newcomb, Polly A., O'Brien, Katie M., Olson, Janet E., Ong, Irene M., Patel, Alpa, Palmer, Julie R., Sandler, Dale P., Tamimi, Rulla, Taylor, Jack A., Teras, Lauren R., Trentham-Dietz, Amy, Vachon, Celine M., Weinberg, Clarice R., Yao, Song, Weitzel, Jeffrey N., Goldgar, David E., Domchek, Susan M., Nathanson, Katherine L., Couch, Fergus J., Kraft, Peter

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Troponin-Guided Coronary Computed Tomographic Angiography After Exclusion of Myocardial Infarction von Lee, Kuan Ken, Bularga, Anda, O'Brien, Rachel, Ferry, Amy, Doudesis, Dimitrios, Fujisawa, Takeshi, Kelly, Shauna, Stewart, Stacey, Wereski, Ryan, Cranley, Denise, van Beek, Edwin J. R., Lowe, David J., Newby, David E., Williams, Michelle C., Gray, Alasdair J., Mills, Nicholas L.

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Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity von Oxley, Thomas J, Opie, Nicholas L, John, Sam E, Rind, Gil S, Ronayne, Stephen M, Wheeler, Tracey L, Judy, Jack W, McDonald, Alan J, Dornom, Anthony, Lovell, Timothy J H, Steward, Christopher, Garrett, David J, Moffat, Bradford A, Lui, Elaine H, Yassi, Nawaf, Campbell, Bruce C V, Wong, Yan T, Fox, Kate E, Nurse, Ewan S, Bennett, Iwan E, Bauquier, Sébastien H, Liyanage, Kishan A, van der Nagel, Nicole R, Perucca, Piero, Ahnood, Arman, Gill, Katherine P, Yan, Bernard, Churilov, Leonid, French, Christopher R, Desmond, Patricia M, Horne, Malcolm K, Kiers, Lynette, Prawer, Steven, Davis, Stephen M, Burkitt, Anthony N, Mitchell, Peter J, Grayden, David B, May, Clive N, O'Brien, Terence J

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Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study von Fendler, Annika, Shepherd, Scott T C, Au, Lewis, Wilkinson, Katalin A, Wu, Mary, Byrne, Fiona, Cerrone, Maddalena, Schmitt, Andreas M, Joharatnam-Hogan, Nalinie, Shum, Benjamin, Tippu, Zayd, Rzeniewicz, Karolina, Boos, Laura Amanda, Harvey, Ruth, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Sarker, Sarah, Lingard, Karla, Mangwende, Mary, Holt, Lucy, Ahmod, Hamid, Korteweg, Justine, Foley, Tara, Bazin, Jessica, Gordon, William, Barber, Taja, Emslie-Henry, Andrea, Xie, Wenyi, Gerard, Camille L, Deng, Daqi, Wall, Emma C, Agua-Doce, Ana, Namjou, Sina, Caidan, Simon, Gavrielides, Mike, MacRae, James I, Kelly, Gavin, Peat, Kema, Kelly, Denise, Murra, Aida, Kelly, Kayleigh, O'Flaherty, Molly, Dowdie, Lauren, Ash, Natalie, Gronthoud, Firza, Shea, Robyn L, Gardner, Gail, Murray, Darren, Kinnaird, Fiona, Cui, Wanyuan, Pascual, Javier, Rodney, Simon, Mencel, Justin, Curtis, Olivia, Stephenson, Clemency, Robinson, Anna, Oza, Bhavna, Farag, Sheima, Leslie, Isla, Rogiers, Aljosja, Iyengar, Sunil, Ethell, Mark, Messiou, Christina, Cunningham, David, Chau, Ian, Starling, Naureen, Turner, Nicholas, Welsh, Liam, van As, Nicholas, Jones, Robin L, Droney, Joanne, Banerjee, Susana, Tatham, Kate C, O'Brien, Mary, Harrington, Kevin, Bhide, Shreerang, Okines, Alicia, Reid, Alison, Young, Kate, Furness, Andrew J S, Pickering, Lisa, Swanton, Charles, Gandhi, Sonia, Gamblin, Steve, Bauer, David Lv, Kassiotis, George, Kumar, Sacheen, Yousaf, Nadia, Jhanji, Shaman, Nicholson, Emma, Howell, Michael, Walker, Susanna, Wilkinson, Robert J, Larkin, James, Turajlic, Samra

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Variants in the fetal genome near FLT1 are associated with risk of preeclampsia von McGinnis, Ralph, Steinthorsdottir, Valgerdur, Williams, Nicholas O, Thorleifsson, Gudmar, Shooter, Scott, Hjartardottir, Sigrun, Bumpstead, Suzannah, Stefansdottir, Lilja, Hildyard, Lucy, Sigurdsson, Jon K, Kemp, John P, Silva, Gabriela B, Thomsen, Liv Cecilie V, Jääskeläinen, Tiina, Kajantie, Eero, Chappell, Sally, Kalsheker, Noor, Moffett, Ashley, Hiby, Susan, Lee, Wai Kwong, Padmanabhan, Sandosh, Simpson, Nigel A B, Dolby, Vivien A, Staines-Urias, Eleonora, Engel, Stephanie M, Haugan, Anita, Trogstad, Lill, Svyatova, Gulnara, Zakhidova, Nodira, Najmutdinova, Dilbar, Dominiczak, Anna F, Gjessing, Håkon K, Casas, Juan P, Dudbridge, Frank, Walker, James J, Pipkin, Fiona Broughton, Thorsteinsdottir, Unnur, Geirsson, Reynir T, Lawlor, Debbie A, Iversen, Ann-Charlotte, Magnus, Per, Laivuori, Hannele, Stefansson, Kari, Morgan, Linda

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Quantum approximate optimization of non-planar graph problems on a planar superconducting processor von Harrigan, Matthew P., Sung, Kevin J., Neeley, Matthew, Satzinger, Kevin J., Arute, Frank, Arya, Kunal, Atalaya, Juan, Bardin, Joseph C., Barends, Rami, Boixo, Sergio, Broughton, Michael, Buckley, Bob B., Buell, David A., Burkett, Brian, Bushnell, Nicholas, Chen, Yu, Chen, Zijun, Ben Chiaro, Collins, Roberto, Courtney, William, Demura, Sean, Dunsworth, Andrew, Eppens, Daniel, Fowler, Austin, Foxen, Brooks, Gidney, Craig, Giustina, Marissa, Graff, Rob, Habegger, Steve, Ho, Alan, Hong, Sabrina, Huang, Trent, Ioffe, L. B., Isakov, Sergei V., Jeffrey, Evan, Jiang, Zhang, Jones, Cody, Kafri, Dvir, Kechedzhi, Kostyantyn, Kelly, Julian, Kim, Seon, Klimov, Paul V., Korotkov, Alexander N., Kostritsa, Fedor, Landhuis, David, Laptev, Pavel, Lindmark, Mike, Leib, Martin, Martin, Orion, Martinis, John M., McClean, Jarrod R., McEwen, Matt, Megrant, Anthony, Mi, Xiao, Mohseni, Masoud, Mruczkiewicz, Wojciech, Mutus, Josh, Naaman, Ofer, Neill, Charles, Neukart, Florian, Niu, Murphy Yuezhen, O’Brien, Thomas E., O’Gorman, Bryan, Ostby, Eric, Petukhov, Andre, Putterman, Harald, Quintana, Chris, Roushan, Pedram, Rubin, Nicholas C., Sank, Daniel, Skolik, Andrea, Smelyanskiy, Vadim, Strain, Doug, Streif, Michael, Szalay, Marco, Vainsencher, Amit, White, Theodore, Yao, Z. Jamie, Yeh, Ping, Zalcman, Adam, Zhou, Leo, Neven, Hartmut, Bacon, Dave, Lucero, Erik, Farhi, Edward, Babbush, Ryan

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Risk of Late-Onset Breast Cancer in Genetically Predisposed Women von Boddicker, Nicholas J., Hu, Chunling, Weitzel, Jeffrey N., Kraft, Peter, Nathanson, Katherine L., Goldgar, David E., Na, Jie, Huang, Hongyan, Gnanaolivu, Rohan D., Larson, Nicole, Yussuf, Amal, Yao, Song, Vachon, Celine M., Trentham-Dietz, Amy, Teras, Lauren, Taylor, Jack A., Scott, Christopher E., Sandler, Dale P., Pesaran, Tina, Patel, Alpa, Palmer, Julie R., Ong, Irene M., Olson, Janet E., O'Brien, Katie, Neuhausen, Susan, Martinez, Elena, Ma, Huiyan, Lindstrom, Sara, Le Marchand, Loic, Kooperberg, Charles, Karam, Rachid, Hunter, David J., Hodge, James M., Haiman, Christopher, Gaudet, Mia M., Gao, Chi, LaDuca, Holly, Lacey, James, Dolinsky, Jill S., Chao, Elizabeth, Carter, Brian D., Burnside, Elizabeth S., Bertrand, Kimberly A., Bernstein, Leslie, Auer, Paul W., Ambrosone, Christine, Yadav, Siddhartha, Hart, Steven N., Polley, Eric C., Domchek, Susan M., Couch, Fergus J.

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Troponin in acute chest pain to risk stratify and guide effective use of computed tomography coronary angiography (TARGET-CTCA): a randomised controlled trial von Lee, Kuan Ken, Lowe, David, O'Brien, Rachel, Wereski, Ryan, Bularga, Anda, Taggart, Caelan, Lowry, Matthew T H, Ferry, Amy V, Williams, Michelle C, Roditi, Giles, Byrne, John, Tuck, Chris, Cranley, Denise, Thokala, Praveen, Goodacre, Steve, Keerie, Catriona, Norrie, John, Newby, David E, Gray, Alasdair J, Mills, Nicholas L

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Density of Upper Respiratory Colonization With Streptococcus pneumoniae and Its Role in the Diagnosis of Pneumococcal Pneumonia Among Children Aged <5 Years in the PERCH Study von Baggett, Henry C., Watson, Nora L., Knoll, Maria Deloria, Brooks, W. Abdullah, Feikin, Daniel R., Hammitt, Laura L., Howie, Stephen R. C., Kotloff, Karen L., Levine, Orin S., Madhi, Shabir A., Murdoch, David R., Scott, J. Anthony G., Thea, Donald M., Antonio, Martin, Awori, Juliet O., Baillie, Vicky L., DeLuca, Andrea N., Driscoll, Amanda J., Duncan, Julie, Ebruke, Bernard E., Goswami, Doli, Higdon, Melissa M., Karron, Ruth A., Moore, David P., Morpeth, Susan C., Mulindwa, Justin M., Park, Daniel E., Paveenkittiporn, Wantana, Piralam, Barameht, Prosperi, Christine, Sow, Samba O., Tapia, Milagritos D., Zaman, Khalequ, Zeger, Scott L., O'Brien, Katherine L.

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Association of C-Reactive Protein With Bacterial and Respiratory Syncytial Virus–Associated Pneumonia Among Children Aged <5 Years in the PERCH Study von Higdon, Melissa M., Le, Tham, O'Brien, Katherine L., Murdoch, David R., Prosperi, Christine, Baggett, Henry C., Brooks, W. Abdullah, Feikin, Daniel R., Hammitt, Laura L., Howie, Stephen R. C., Kotloff, Karen L., Levine, Orin S., Scott, J. Anthony G., Thea, Donald M., Awori, Juliet O., Baillie, Vicky L., Cascio, Stephanie, Chuananon, Somchai, DeLuca, Andrea N., Driscoll, Amanda J., Ebruke, Bernard E., Endtz, Hubert P., Kaewpan, Anek, Kahn, Geoff, Karani, Angela, Karron, Ruth A., Moore, David P., Park, Daniel E., Rahman, Mohammed Ziaur, Salaudeen, Rasheed, Seidenberg, Phil, Somwe, Somwe Wa, Sylla, Mamadou, Tapia, Milagritos D., Zeger, Scott L., Knoll, Maria Deloria, Madhi, Shabir A.

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