Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS‐790052 in Humans: In Vitro and In Vivo Corre... von Fridell, Robert A., Wang, Chunfu, Sun, Jin‐Hua, O'Boyle, Donald R., Nower, Peter, Valera, Lourdes, Qiu, Dike, Roberts, Susan, Huang, Xin, Kienzle, Bernadette, Bifano, Marc, Nettles, Richard E., Gao, Min

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Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir von CHUNFU WANG, SUN, Jin-Hua, O'BOYLE, Donald R, NOWER, Peter, VALERA, Lourdes, ROBERTS, Susan, FRIDELL, Robert A, MIN GAO

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Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052 von Wang, Chunfu, Huang, Haichang, Valera, Lourdes, Sun, Jin-Hua, O'Boyle, Donald R., II, Nower, Peter T, Jia, Lingling, Qiu, Dike, Huang, Xin, Altaf, Aneela, Gao, Min, Fridell, Robert A

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Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activity von Wang, Chunfu, Jia, Lingling, O'Boyle, 2nd, Donald R, Sun, Jin-Hua, Rigat, Karen, Valera, Lourdes, Nower, Peter, Huang, Xin, Kienzle, Bernadette, Roberts, Susan, Gao, Min, Fridell, Robert A

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HCV NS5A replication complex inhibitors von Gao, Min, O’Boyle, Donald R, Roberts, Susan

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Discovery and Development of Hepatitis C Virus NS5A Replication Complex Inhibitors von Belema, Makonen, Lopez, Omar D., Bender, John A., Romine, Jeffrey L., St. Laurent, Denis R., Langley, David R., Lemm, Julie A., O’Boyle, Donald R., Sun, Jin-Hua, Wang, Chunfu, Fridell, Robert A., Meanwell, Nicholas A.

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Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A von Sun, Jin-Hua, O’Boyle II, Donald R., Fridell, Robert A., Langley, David R., Wang, Chunfu, Roberts, Susan B., Nower, Peter, Johnson, Benjamin M., Moulin, Frederic, Nophsker, Michelle J., Wang, Ying-Kai, Liu, Mengping, Rigat, Karen, Tu, Yong, Hewawasam, Piyasena, Kadow, John, Meanwell, Nicholas A., Cockett, Mark, Lemm, Julie A., Kramer, Melissa, Belema, Makonen, Gao, Min

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Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5a replication complex inhibitor, BMS-790052 von Sun, Jin-Hua, O'Boyle II, Donald R., Zhang, Yan, Wang, Chunfu, Nower, Peter, Valera, Lourdes, Roberts, Susan, Nettles, Richard E., Fridell, Robert A., Gao, Min

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In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A von Wang, Chunfu, Jia, Lingling, Huang, Haichang, Qiu, Dike, Valera, Lourdes, Huang, Xin, Sun, Jin-Hua, Nower, Peter T, O'Boyle, 2nd, Donald R, Gao, Min, Fridell, Robert A

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Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures von Lemm, Julie A, Leet, John E, O'Boyle, 2nd, Donald R, Romine, Jeffrey L, Huang, Xiaohua Stella, Schroeder, Daniel R, Alberts, Jeffrey, Cantone, Joseph L, Sun, Jin-Hua, Nower, Peter T, Martin, Scott W, Serrano-Wu, Michael H, Meanwell, Nicholas A, Snyder, Lawrence B, Gao, Min

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Hepatitis C Virus NS5A Replication Complex Inhibitors. Part 6: Discovery of a Novel and Highly Potent Biarylimidazole Chemotype with Inhibitory Activity Toward Genotypes 1a and 1b... von Belema, Makonen, Nguyen, Van N., Romine, Jeffrey L., St. Laurent, Denis R., Lopez, Omar D., Goodrich, Jason T., Nower, Peter T., O’Boyle, Donald R., Lemm, Julie A., Fridell, Robert A., Gao, Min, Fang, Hua, Krause, Rudolph G., Wang, Ying-Kai, Oliver, A. Jayne, Good, Andrew C., Knipe, Jay O., Meanwell, Nicholas A., Snyder, Lawrence B.

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Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect von Meanwell, Nicholas A, Gao, Min, Nettles, Richard E, Belema, Makonen, Snyder, Lawrence B, Nguyen, Van N, Fridell, Robert A, Serrano-Wu, Michael H, Langley, David R, Sun, Jin-Hua, O’Boyle II, Donald R, Lemm, Julie A, Wang, Chunfu, Knipe, Jay O, Chien, Caly, Colonno, Richard J, Grasela, Dennis M, Hamann, Lawrence G

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Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes von Romine, Jeffrey L, St. Laurent, Denis R, Leet, John E, Martin, Scott W, Serrano-Wu, Michael H, Yang, Fukang, Gao, Min, O’Boyle, Donald R, Lemm, Julie A, Sun, Jin-Hua, Nower, Peter T, Huang, Xiaohua (Stella), Deshpande, Milind S, Meanwell, Nicholas A, Snyder, Lawrence B

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A 96-well based analysis of replicon elimination with the HCV NS5A replication complex inhibitor daclatasvir von O’Boyle, Donald R., Nower, Peter T., Sun, Jin-Hua, Fridell, Robert, Wang, Chunfu, Valera, Lourdes, Gao, Min

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HCV NS5A replication complex inhibitors. Part 5: Discovery of potent and pan-genotypic glycinamide cap derivatives von Belema, Makonen, Nguyen, Van N., St. Laurent, Denis R., Lopez, Omar D., Qiu, Yuping, Good, Andrew C., Nower, Peter T., Valera, Lourdes, O’Boyle, Donald R., Sun, Jin-Hua, Liu, Mengping, Fridell, Robert A., Lemm, Julie A., Gao, Min, Knipe, Jay O., Meanwell, Nicholas A., Snyder, Lawrence B.

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Synergistic Activity of Combined NS5A Inhibitors von O'Boyle, 2nd, Donald R, Nower, Peter T, Gao, Min, Fridell, Robert, Wang, Chunfu, Hewawasam, Piyasena, Lopez, Omar, Tu, Yong, Meanwell, Nicholas A, Belema, Makonen, Roberts, Susan B, Cockett, Mark, Sun, Jin-Hua

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Development of a Cell-Based High-Throughput Specificity Screen Using a Hepatitis C Virus-Bovine Viral Diarrhea Virus Dual Replicon Assay von O'BOYLE, Donald R, NOWER, Peter T, LEMM, Julie A, VALERA, Lourdes, SUN, Jin-Hua, RIGAT, Karen, COLONNO, Richard, MIN GAO

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Specific Inhibition of Bovine Viral Diarrhea Virus Replicase von Sun, Jin-Hua, Lemm, Julie A, O'Boyle, 2nd, Donald R, Racela, Jason, Colonno, Richard, Gao, Min

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Characterizations of HCV NS5A replication complex inhibitors von O'Boyle II, Donald R, Sun, Jin-Hua, Nower, Peter T, Lemm, Julie A, Fridell, Robert A, Wang, Chunfu, Romine, Jeffrey L, Belema, Makonen, Nguyen, Van N, Laurent, Denis R. St, Serrano-Wu, Michael, Snyder, Lawrence B, Meanwell, Nicholas A, Langley, David R, Gao, Min

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effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization von Qiu, Dike, Lemm, Julie A, O’Boyle, Donald R., II, Sun, Jin-Hua, Nower, Peter T, Nguyen, Van, Hamann, Lawrence G, Snyder, Lawrence B, Deon, Daniel H, Ruediger, Edward, Meanwell, Nicholas A, Belema, Makonen, Gao, Min, Fridell, Robert A

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