Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma von Scott, Milcah C, Temiz, Nuri A, Sarver, Anne E, LaRue, Rebecca S, Rathe, Susan K, Varshney, Jyotika, Wolf, Natalie K, Moriarity, Branden S, O'Brien, Timothy D, Spector, Logan G, Largaespada, David A, Modiano, Jaime F, Subramanian, Subbaya, Sarver, Aaron L

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Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys von Nicol, Lindsey E, O'Brien, Timothy D, Dumesic, Daniel A, Grogan, Tristan, Tarantal, Alice F, Abbott, David H

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Artificial intelligence (AI)-assisted exome reanalysis greatly aids in the identification of new positive cases and reduces analysis time in a clinical diagnostic laboratory von O’Brien, Timothy D., Campbell, N. Eleanor, Potter, Amiee B., Letaw, John H., Kulkarni, Arpita, Richards, C. Sue

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Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium von Lindborg, Beth A., Brekke, John H., Vegoe, Amanda L., Ulrich, Connor B., Haider, Kerri T., Subramaniam, Sandhya, Venhuizen, Scott L., Eide, Cindy R., Orchard, Paul J., Chen, Weili, Wang, Qi, Pelaez, Francisco, Scott, Carolyn M., Kokkoli, Efrosini, Keirstead, Susan A., Dutton, James R., Tolar, Jakub, O'Brien, Timothy D.

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Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold von Holladay, Carolyn A, Duffy, Aoife M, Chen, Xizhe, Sefton, Michael V, O’Brien, Timothy D, Pandit, Abhay S

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Weak sharing of genetic association signals in three lung cancer subtypes: evidence at the SNP, gene, regulation, and pathway levels von O'Brien, Timothy D, Jia, Peilin, Caporaso, Neil E, Landi, Maria Teresa, Zhao, Zhongming

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Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning von Makielski, Kelly M., Donnelly, Alicia J., Khammanivong, Ali, Scott, Milcah C., Ortiz, Andrea R., Galvan, Dana C., Tomiyasu, Hirotaka, Amaya, Clarissa, Ward, Kristin A., Montoya, Alexa, Garbe, John R., Mills, Lauren J., Cutter, Gary R., Fenger, Joelle M., Kisseberth, William C., O'Brien, Timothy D., Weigel, Brenda J., Spector, Logan G., Bryan, Brad A., Subramanian, Subbaya, Modiano, Jaime F.

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Proteomic analysis of highly prevalent amyloid A amyloidosis endemic to endangered island foxes von Gaffney, Patricia M, Imai, Denise M, Clifford, Deana L, Ghassemian, Majid, Sasik, Roman, Chang, Aaron N, O'Brien, Timothy D, Coppinger, Judith, Trejo, Margarita, Masliah, Eliezer, Munson, Linda, Sigurdson, Christina

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Identification of Three Molecular and Functional Subtypes in Canine Hemangiosarcoma through Gene Expression Profiling and Progenitor Cell Characterization von Gorden, Brandi H, Kim, Jong-Hyuk, Sarver, Aaron L, Frantz, Aric M, Breen, Matthew, Lindblad-Toh, Kerstin, O'Brien, Timothy D, Sharkey, Leslie C, Modiano, Jaime F, Dickerson, Erin B

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Population screening shows risk of inherited cancer and familial hypercholesterolemia in Oregon von O’Brien, Timothy D., Potter, Amiee B., Driscoll, Catherine C., Goh, Gregory, Letaw, John H., McCabe, Sarah, Thanner, Jane, Kulkarni, Arpita, Wong, Rossana, Medica, Samuel, Week, Tiana, Buitrago, Jacob, Larson, Aaron, Camacho, Katie Johnson, Brown, Kim, Crist, Rachel, Conrad, Casey, Evans-Dutson, Sara, Lutz, Ryan, Mitchell, Asia, Anur, Pavana, Serrato, Vanessa, Shafer, Autumn, Marriott, Lisa K., Hamman, K.J., Mulford, Amelia, Wiszniewski, Wojciech, Sampson, Jone E., Adey, Andrew, O’Roak, Brian J., Harrington, Christina A., Shannon, Jackilen, Spellman, Paul T., Richards, C. Sue

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Clinically available immunosuppression averts rejection but not systemic inflammation after porcine islet xenotransplant in cynomolgus macaques von Graham, Melanie L., Ramachandran, Sabarinathan, Singh, Amar, Moore, Meghan E. G., Flanagan, E. Brian, Azimzadeh, Agnes, Burlak, Christopher, Mueller, Kate R., Martins, Kyra, Anazawa, Takayuki, Appakalai, Balamurugan N., Bansal‐Pakala, Pratima, Murtaugh, Michael P., O'Brien, Timothy D., Papas, Klearchos K., Spizzo, Thomas, Schuurman, Henk‐J., Hancock, Wayne W., Hering, Bernhard. J.

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Spheroid Culture for Enhanced Differentiation of Human Embryonic Stem Cells to Hepatocyte-Like Cells von Subramanian, Kartik, Owens, Derek Jason, Raju, Ravali, Firpo, Meri, O'Brien, Timothy D., Verfaillie, Catherine M., Hu, Wei-Shou

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Nano-engineered mesenchymal stem cells as targeted therapeutic carriers von Sadhukha, Tanmoy, O'Brien, Timothy D., Prabha, Swayam

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Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes von Kim, Jong-Hyuk, Furrow, Eva, Ritt, Michelle G, Utz, Paul J, Robinson, William H, Yu, Liping, Eckert, Andrea, Stuebner, Kathleen, O'Brien, Timothy D, Steinman, Lawrence, Modiano, Jaime F

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Inconsistency and features of single nucleotide variants detected in whole exome sequencing versus transcriptome sequencing: A case study in lung cancer von O’Brien, Timothy D., Jia, Peilin, Xia, Junfeng, Saxena, Uma, Jin, Hailing, Vuong, Huy, Kim, Pora, Wang, Qingguo, Aryee, Martin J., Mino-Kenudson, Mari, Engelman, Jeffrey A., Le, Long P., Iafrate, A. John, Heist, Rebecca S., Pao, William, Zhao, Zhongming

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Lung Cancer: One Disease or Many? von O’Brien, Timothy D., Jia, Peilin, Aldrich, Melinda C., Zhao, Zhongming

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Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment von Kim, Jong-Hyuk, Frantz, Aric M., Anderson, Katie L., Graef, Ashley J., Scott, Milcah C., Robinson, Sally, Sharkey, Leslie C., O׳Brien, Timothy D., Dickerson, Erin B., Modiano, Jaime F.

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What is your diagnosis? Nasal lesion in a horse with exophthalmos von Zibura, Ashley E., Manning, Leah K., Gwynn, Angela, Sharkey, Leslie, Linde Henriksen, Michala, Coppelman, Elizabeth, O’Brien, Timothy D.

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Interspecies Organogenesis for Human Transplantation von Crane, Andrew T., Aravalli, Rajagopal N., Asakura, Atsushi, Grande, Andrew W., Krishna, Venkatramana D., Carlson, Daniel F., Cheeran, Maxim C.-J., Danczyk, Georgette, Dutton, James R., Hackett, Perry B., Hu, Wei-Shou, Li, Ling, Lu, Wei-Cheng, Miller, Zachary D., O’Brien, Timothy D., Panoskaltsis-Mortari, Angela, Parr, Ann M., Pearce, Clairice, Ruiz-Estevez, Mercedes, Shiao, Maple, Sipe, Christopher J., Toman, Nikolas G., Voth, Joseph, Xie, Hui, Steer, Clifford J., Low, Walter C.

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A bioengineered artificial interstitium supports long-term islet xenograft survival in nonhuman primates without immunosuppression von Oppler, Scott H, Hocum Stone, Laura L, Leishman, David J, Janecek, Jody L, Moore, Meghan E G, Rangarajan, Parthasarathy, Willenberg, Bradley J, O'Brien, Timothy D, Modiano, Jaime, Pheil, Natan, Dalton, Jordan, Dalton, Michael, Ramachandran, Sabarinathan, Graham, Melanie L

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