Farnesyltransferase inhibitors reverse taxane resistance von MARCUS, Adam I, O'BRATE, Aurora M, BUEY, Ruben M, JUN ZHOU, THOMAS, Shala, KHURI, Fadlo R, ANDREU, Jose Manuel, DIAZ, Fernando, GIANNAKAKOU, Paraskevi

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Enhanced Microtubule-Dependent Trafficking and p53 Nuclear Accumulation by Suppression of Microtubule Dynamics von Giannakakou, Paraskevi, Nakano, Michel, Nicolaou, Kyriacos C., O'Brate, Aurora, Yu, Jian, Blagosklonny, Mikhail V., Greber, Urs F., Fojo, Tito

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Chemistry and Biology of Diazonamide A:  Second Total Synthesis and Biological Investigations von Nicolaou, K. C, Hao, Junliang, Reddy, Mali V, Rao, Paraselli Bheema, Rassias, Gerasimos, Snyder, Scott A, Huang, Xianhai, Chen, David Y.-K, Brenzovich, William E, Giuseppone, Nicolas, Giannakakou, Paraskevi, O'Brate, Aurora

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Tepotinib plus osimertinib in patients with EGFR-mutated non-small-cell lung cancer with MET amplification following progression on first-line osimertinib (INSIGHT 2): a multicentr... von Wu, Yi-Long, Guarneri, Valentina, Voon, Pei Jye, Lim, Boon Khaw, Yang, Jin-Ji, Wislez, Marie, Huang, Cheng, Liam, Chong Kin, Mazieres, Julien, Tho, Lye Mun, Hayashi, Hidetoshi, Nhung, Nguyen Viet, Chia, Puey Ling, de Marinis, Filippo, Raskin, Jo, Zhou, Qinghua, Finocchiaro, Giovanna, Le, Anh Tuan, Wang, Jialei, Dooms, Christophe, Kato, Terufumi, Nadal, Ernest, Hin, How Soon, Smit, Egbert F, Wermke, Martin, Tan, Daniel, Morise, Masahiro, O'Brate, Aurora, Adrian, Svenja, Pfeiffer, Boris M, Stroh, Christopher, Juraeva, Dilafruz, Strotmann, Rainer, Goteti, Kosalaram, Berghoff, Karin, Ellers-Lenz, Barbara, Karachaliou, Niki, Le, Xiuning, Kim, Tae Min

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The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Acti... von Pryor, Donald E, O'Brate, Aurora, Bilcer, Geoffrey, Díaz, J. Fernando, Wang, Yuefang, Wang, Yong, Kabaki, Mikio, Jung, M. Katherine, Andreu, José M, Ghosh, Arun K, Giannakakou, Paraskevi, Hamel, Ernest

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Discovery of a Biologically Active Thiostrepton Fragment von Nicolaou, K. C, Zak, Mark, Rahimipour, Shai, Estrada, Anthony A, Lee, Sang Hyup, O'Brate, Aurora, Giannakakou, Paraskevi, Ghadiri, M. Reza

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Paclitaxel Resistance in Non–Small-Cell Lung Cancer Associated With Beta-Tubulin Gene Mutations von Monzó, M, Rosell, R, Sánchez, J J, Lee, J S, O'Brate, A, González-Larriba, J L, Alberola, V, Lorenzo, J C, Núñez, L, Ro, J Y, Martín, C

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Brief Report: Clinical Response, Toxicity, and Resistance Mechanisms to Osimertinib Plus MET Inhibitors in Patients With EGFR-Mutant MET-Amplified NSCLC von Wang, Kaiwen, Du, Robyn, Roy-Chowdhuri, Sinchita, Li, Ziping T., Hong, Lingzhi, Vokes, Natalie, Elamin, Yasir Y., Hume, Celyne Bueno, Skoulidis, Ferdinandos, Gay, Carl M., Blumenschein, George, Fossella, Frank V., Tsao, Anne, Zhang, Jianjun, Karachaliou, Niki, O’Brate, Aurora, Gann, Claudia-Nanette, Lewis, Jeff, Rinsurongkawong, Waree, Lee, Jack, Gibbons, Don Lynn, Vaporciyan, Ara A., Heymach, John V., Altan, Mehmet, Le, Xiuning

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Design, Synthesis, and Biological Properties of Highly Potent Epothilone B Analogues von Nicolaou, K. C., Sasmal, Pradip K., Rassias, Gerasimos, Reddy, Mali Venkat, Altmann, Karl-Heinz, Wartmann, Markus, O'Brate, Aurora, Giannakakou, Paraskevi

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Studies toward Diazonamide A:  Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure von Nicolaou, K. C, Snyder, Scott A, Giuseppone, Nicolas, Huang, Xianhai, Bella, Marco, Reddy, Mali V, Rao, Paraselli Bheema, Koumbis, Alexandros E, Giannakakou, Paraskevi, O'Brate, Aurora

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Chemical synthesis and biological evaluation of novel epothilone B and trans-12,13-cyclopropyl epothilone B analogues von Nicolaou, K.C, Ritzén, Andreas, Namoto, Kenji, Buey, Rubén M, Dı́az, J.Fernando, Andreu, José M, Wartmann, Markus, Altmann, Karl-Heinz, O'Brate, Aurora, Giannakakou, Paraskevi

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Predictive molecular markers in non–small cell lung cancer von Rosell, Rafael, Tarón, Miquel, O’Brate, Aurora

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PP01.84 Tepotinib + Osimertinib in EGFR-mutant NSCLC with MET Amplification Following 1L Osimertinib: INSIGHT 2 Primary Analysis von Kim, Tae Min, Guarneri, Valentina, Voon, Pei Jye, Lim, Boon Khaw, Yang, Jin-ji, Wislez, Marie, Huang, Cheng, Liam, Chong Kin, Mazieres, Julien, Tho, ye Mun, Hayashi, Hidetoshi, Nguyen, Nhung, Chia, Puey Ling, de Marinis, Filippo, Raskin, Jo, Zhou, Qinghua, Finocchiaro, Giovanna, Le, Xiuning, Tan, Daniel, O’Hara, Richard M., Brutlach, Sabine, O’Brate, Aurora, Adrian, Svenja, Berghoff, Karin, Ellers-Lenz, Barbara, Karachaliou, Niki, Wu, Yi-Long

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Translational oncogenomics: toward rational therapeutic decision-making von Rosell, Rafael, Monzo, Mariano, O'Brate, Aurora, Taron, Miquel

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Intracranial activity of tepotinib in patients (pts) with MET exon 14 ( MET ex14) skipping NSCLC enrolled in VISION von Patel, Jyoti D., Le, Xiuning, Veillon, Remi, Anderson, Ian Churchill, Bestvina, Christine M., Demedts, Ingel, Garassino, Marina Chiara, Mazieres, Julien, Morise, Masahiro, Smit, Egbert F., Eggleton, S. Peter, OBrate, Aurora, Otto, Gordon, Bruns, Rolf, Schumacher, Karl-Maria, Paik, Paul K.

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Studies toward Diazonamide A:  Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure [... von Nicolaou, K. C, Snyder, Scott A, Giuseppone, Nicolas, Huang, Xianhai, Bella, Marco, Reddy, Mali V, Bheema Rao, Paraselli, Koumbis, Alexandros E, Giannakakou, Paraskevi, O'Brate, Aurora

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Chemistry and Biology of Diazonamide A:  Second Total Synthesis and Biological Investigations [J. Am. Chem. Soc. 2004, 126, 12897−12906] von Nicolaou, K. C, Hao, Junliang, Reddy, Mali V, Bheema Rao, Paraselli, Rassias, Gerasimos, Snyder, Scott A, Huang, Xianhai, Chen, David Y.-K, Brenzovich, William E, Giuseppone, Nicolas, Giannakakou, Paraskevi, O'Brate, Aurora

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TRLS-03. Intracranial activity of tepotinib in patients with MET exon 14 ( MET ex14) skipping NSCLC enrolled in VISION von Bestvina, Christine M, Le, Xiuning, Veillon, Remi, Anderson, Ian, Patel, Jyoti, Demedts, Ingel, Garassino, Marina, Mazières, Julien, Morise, Masahiro, Smit, Egbert, Eggleton, S Peter, O’Brate, Aurora, Otto, Gordon, Bruns, Rolf, Schumacher, Karl Maria, Paik, Paul

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Sharing New Approaches to Translational Research in Non‐Small Cell Lung Cancer von O'Brate, Aurora, Tarón, Miquel, Gandara, David, Rosell, Rafael

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Novel approaches in the treatment of non-small-cell lung cancer von Rosell, R, Sánchez, J M, Tarón, M, O'Brate, A, Gutiérrez, J L, Monzó, M, Felip, E, Sánchez, J J, Alberola, V

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