Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease von Phillips, Bridget, Western, Daniel, Wang, Lihua, Timsina, Jigyasha, Sun, Yichen, Gorijala, Priyanka, Yang, Chengran, Do, Anh, Nykänen, Niko-Petteri, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Morris, John C., Schindler, Suzanne E., Fagan, Anne M., Puerta, Raquel, García-González, Pablo, de Rojas, Itziar, Marquié, Marta, Boada, Mercè, Ruiz, Agustin, Perlmutter, Joel S., Ibanez, Laura, Perrin, Richard J., Sung, Yun Ju, Cruchaga, Carlos

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Pleiotropic effect of LRRK2 on Parkinson‐associated proteins and processing of pathological alpha‐synuclein in myeloid cells von Nykanen, Niko‐Petteri, Yang, Chengran, Harari, Oscar, Davis, Albert A, Cruchaga, Carlos, Benitez, Bruno A.

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FRMD4A-cytohesin signaling modulates the cellular release of tau von Yan, Xu, Nykänen, Niko-Petteri, Brunello, Cecilia A, Haapasalo, Annakaisa, Hiltunen, Mikko, Uronen, Riikka-Liisa, Huttunen, Henri J

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Alpha-synuclein fragments trigger distinct aggregation pathways von Chakroun, Tasnim, Evsyukov, Valentin, Nykänen, Niko-Petteri, Höllerhage, Matthias, Schmidt, Andreas, Kamp, Frits, Ruf, Viktoria C., Wurst, Wolfgang, Rösler, Thomas W., Höglinger, Günter U.

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Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models von Martiskainen, Henna, Viswanathan, Jayashree, Nykänen, Niko-Petteri, Kurki, Mitja, Helisalmi, Seppo, Natunen, Teemu, Sarajärvi, Timo, Kurkinen, Kaisa M.A, Pursiheimo, Juha-Pekka, Rauramaa, Tuomas, Alafuzoff, Irina, Jääskeläinen, Juha E, Leinonen, Ville, Soininen, Hilkka, Haapasalo, Annakaisa, Huttunen, Henri J, Hiltunen, Mikko

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γ-Aminobutyric Acid Type A (GABAA) Receptor Activation Modulates Tau Phosphorylation von Nykänen, Niko-Petteri, Kysenius, Kai, Sakha, Prasanna, Tammela, Päivi, Huttunen, Henri J.

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Multiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP) von Merezhko, Maria, Muggalla, Pranuthi, Nykänen, Niko-Petteri, Yan, Xu, Sakha, Prasanna, Huttunen, Henri J

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Four-repeat tauopathies von Rösler, Thomas W, Tayaranian Marvian, Amir, Brendel, Matthias, Nykänen, Niko-Petteri, Höllerhage, Matthias, Schwarz, Sigrid C, Hopfner, Franziska, Koeglsperger, Thomas, Respondek, Gesine, Schweyer, Kerstin, Levin, Johannes, Villemagne, Victor L, Barthel, Henryk, Sabri, Osama, Müller, Ulrich, Meissner, Wassilios G, Kovacs, Gabor G, Höglinger, Günter U

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Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy von Fussi, Natascha, Höllerhage, Matthias, Chakroun, Tasnim, Nykänen, Niko-Petteri, Rösler, Thomas W., Koeglsperger, Thomas, Wurst, Wolfgang, Behrends, Christian, Höglinger, Günter U.

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Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes von Findeiss, Elisabeth, Schwarz, Sigrid C, Evsyukov, Valentin, Rösler, Thomas W, Höllerhage, Matthias, Chakroun, Tasnim, Nykänen, Niko-Petteri, Shen, Yimin, Wurst, Wolfgang, Kohl, Michael, Tost, Jörg, Höglinger, Günter U

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Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease von Wang, Lihua, Nykänen, Niko-Petteri, Western, Daniel, Gorijala, Priyanka, Timsina, Jigyasha, Li, Fuhai, Wang, Zhaohua, Ali, Muhammad, Yang, Chengran, Liu, Menghan, Brock, William, Marquié, Marta, Boada, Mercè, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Ruiz, Agustín, Puerta, Raquel, Orellana, Adelina, Rutledge, Jarod, Oh, Hamilton, Greicius, Michael D, Le Guen, Yann, Perrin, Richard J, Wyss-Coray, Tony, Jefferson, Angela, Hohman, Timothy J, Graff-Radford, Neill, Mori, Hiroshi, Goate, Alison, Levin, Johannes, Sung, Yun Ju, Cruchaga, Carlos

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A cell‐autonomous role of DNAJC5 in microglial‐mediated proteostasis in Alzheimer’s disease von Rosene, Matthew J, Nykanen, Niko‐Petteri, Brase, Logan, Harari, Oscar, Benitez, Bruno A.

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circRNAs mediate the effect of chronic lysosomal dysfunction on Alzheimer’s disease pathology von Romero, Skarleth Cardenas, Eteleeb, Abdallah M, Nykanen, Niko‐Petteri, O’Dell, Kevin, Nunez, Marie, Harari, Oscar, Cirrito, John R, Sands, Mark, Benitez, Bruno A.

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Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures von Rouhiainen, Ari, Nykänen, Niko-Petteri, Kuja-Panula, Juha, Vanttola, Päivi, Huttunen, Henri J, Rauvala, Heikki

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Proteo‐genomics of soluble TREM2 in cerebrospinal fluid provides novel insights for TREM2 biology and identifies novel modulators for Alzheimer’s disease von Wang, Lihua, Nykanen, Niko‐Petteri, Western, Daniel, Gorijala, Priyanka, Timsina, Jigyasha, Marquié, Marta, Boada, Mercè, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Ruiz, Agustin, Hohman, Timothy J., Wyss‐Coray, Tony, Sung, Yun Ju, Cruchaga, Carlos

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Proteome Wide Association Studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease von Phillips, Bridget, Western, Daniel, Wang, Lihua, Timsina, Jigyasha, Sun, Yichen, Gorijala, Priyanka, Yang, Chengran, Do, Anh, Nykanen, Niko‐Petteri, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Morris, John C, Schindler, Suzanne E., Fagan, Anne M., Puerta, Raquel, García‐González, Pablo, de Rojas, Itziar, Marquié, Marta, Boada, Mercè, Ruiz, Agustin, Perlmutter, Joel S., Ibanez, Laura, Perrin, Richard J., Sung, Yun Ju, Cruchaga, Carlos

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400. An Alzheimer’s Disease-Associated circRNA Regulates Long App and MAPT mRNA Isoform Expression von Papageorgiou, Grigorios, Hernandez, Megan, Maxson, Gabriella, Varangis, Michael, Nykänen, Niko-Petteri, Brigman, Jonathan, Benitez, Bruno, Cruchaga, Carlos, Mellios, Nikolaos

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Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease von Wang, Lihua, Nykänen, Niko-Petteri, Western, Daniel, Gorijala, Priyanka, Timsina, Jigyasha, Li, Fuhai, Wang, Zhaohua, Ali, Muhammad, Yang, Chengran, Liu, Menghan, Brock, William, Marquié, Marta, Boada, Mercè, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Ruiz Laza, Agustín, Puerta, Raquel, Orellana, Adelina, Rutledge, Jarod, Oh, Hamilton, Greicius, Michael. D, Le Guen, Yann Le, Perrin, Richard J, Wyss-Coray, Tony, Jefferson, Angela, Hohman, Timothy J, Graff-Radford, Neill, Mori, Hiroshi, Goate, Alison, Levin, Johannes, Sung, Yun Ju, Cruchaga, Carlos, Universitat Autònoma de Barcelona

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Additional file 2 of Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease von Wang, Lihua, Nykänen, Niko-Petteri, Western, Daniel, Gorijala, Priyanka, Timsina, Jigyasha, Li, Fuhai, Wang, Zhaohua, Ali, Muhammad, Yang, Chengran, Liu, Menghan, Brock, William, Marquié, Marta, Boada, Mercè, Alvarez, Ignacio, Aguilar, Miquel, Pastor, Pau, Ruiz, Agustín, Puerta, Raquel, Orellana, Adelina, Rutledge, Jarod, Oh, Hamilton, Greicius, Michael D, Le Guen, Yann, Perrin, Richard J., Wyss-Coray, Tony, Jefferson, Angela, Hohman, Timothy J., Graff-Radford, Neill, Mori, Hiroshi, Goate, Alison, Levin, Johannes, Sung, Yun Ju, Cruchaga, Carlos

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Exosomal secretion of alpha-synuclein as protective mechanism after upstream blockage of macroautophagy von Fussi, Natascha, Höllerhage, Matthias, Chakroun, Tasnim, Nykänen, Niko-Petteri, Roesler, Thomas W, Köglsperger, Thomas, Wurst, Wolfgang, Behrends, Christian, Höglinger, Guenter U

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