The significance of gradient expression of chromosome region maintenance protein 1 (exportin1) in large cell lymphoma von Abeykoon, Jithma P, Hampel, Paul J, King, Rebecca L, Wood, Adam J, Larson, Melissa C, Nowakowski, Kevin E, Zanwar, Saurabh S, Dasari, Surendra, Ruan, Gordon J, Ravindran, Aishwarya, Wellik, Linda E, Paludo, Jonas, Link, Brian K, Cerhan, James R, Ansell, Stephen M, Nowakowski, Grzegorz S, Thompson, Carrie A, Maurer, Matthew J, Wenzl, Kerstin, Novak, Anne J, Wu, Xiaosheng, Habermann, Thomas M, Witzig, Thomas E

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Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19 von Wu, Xiaosheng, Manske, Michelle K., Ruan, Gordon J., Witter, Taylor L., Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xinyi, Yu, Yue, Gwin, Kimberly A., Wu, Annie, Taupin, Vanessa, Bhardwaj, Vaishali, Paludo, Jonas, Dasari, Surendra, Dong, Haidong, Ansell, Stephen M., Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.

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Salicylates enhance CRM1 inhibitor antitumor activity by induction of S-phase arrest and impairment of DNA-damage repair von Abeykoon, Jithma P., Wu, Xiaosheng, Nowakowski, Kevin E., Dasari, Surendra, Paludo, Jonas, Weroha, S. John, Hu, Chunling, Hou, Xiaonan, Sarkaria, Jann N., Mladek, Ann C., Phillips, Jessica L., Feldman, Andrew L., Ravindran, Aishwarya, King, Rebecca L., Boysen, Justin, Stenson, Mary J., Carr, Ryan M., Manske, Michelle K., Molina, Julian R., Kapoor, Prashant, Parikh, Sameer A., Kumar, Shaji, Robinson, Steven I., Yu, Jia, Boughey, Judy C., Wang, Liewei, Goetz, Matthew P., Couch, Fergus J., Patnaik, Mrinal M., Witzig, Thomas E.

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Sustained, complete response to pexidartinib in a patient with CSF1R‐mutated Erdheim–Chester disease von Abeykoon, Jithma P., Lasho, Terra L., Dasari, Surendra, Rech, Karen L., Ranatunga, Wasantha K., Manske, Michelle K., Tischer, Alexander, Ravindran, Aishwarya, Young, Jason R., Tobin, William Oliver, Flanagan, Eoin P., Nowakowski, Kevin E., Ruan, Gordon J., Shah, Mithun V., Bennani, Nabila Nora, Vassallo, Robert, Ryu, Jay H., Koster, Matthew J., Davidge‐Pitts, Caroline J., Patnaik, Mrinal M., Wu, Xiaosheng, Witzig, Thomas E., Goyal, Gaurav, Go, Ronald S.

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MCIR1: A patient‐derived mantle cell lymphoma line for discovering new treatments for ibrutinib resistance von Wu, Xiaosheng, Nowakowski, Kevin E., Abeykoon, Jithma P., Manske, Michelle, Stenson, Mary J., Timm, Michael M., Hanson, Curtis A., Van Dyke, Daniel L., Dasari, Surendra, Witzig, Thomas E.

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The effect of CRM1 inhibition on human non-Hodgkin lymphoma cells von Abeykoon, Jithma P., Paludo, Jonas, Nowakowski, Kevin E., Stenson, Mary J., King, Rebecca L., Wellik, Linda E., Wu, Xiaosheng, Witzig, Thomas E.

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Secreted Sars-Cov-2 Encoded ORF8 Protein Stimulates Pro-Inflammatory Cytokines and Predicts Severe Clinical Outcome von Manske, Michelle K., Wu, Xiaosheng, Ruan, Gordon, Witter, Taylor L., Gwin, Kimberly, Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xinyi, Yu, Yue, Paludo, Jonas, Dasari, Surendra, Ansell, Stephen M., Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.

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The SARS-CoV-2 encoded ORF8 protein Stimulates Human Monocytes to Produce Pro-Inflammatory Cytokines von Ruan, Gordon J, Wu, Xiaosheng, Manske, Michelle K., Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xingyi, Yu, Yue, Witter, Taylor L., Taupin, Vanessa, Paludo, Jonas, Ansell, Stephen M, Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.

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Abstract 650: MCIR1: A patient-derived ibrutinib-resistant mantle cell lymphoma line for the study of ibrutinib resistance and drug discovery von Nowakowski, Kevin E., Abeykoon, Jithma P., Stenson, Mary J., Timm, Michael M., Hanson, Curtis A., Van Dyke, Daniel L., Novak, Anne J., Wu, Xiaosheng, Witzig, Thomas E.

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The Expression of Chromosome Region Maintenance Protein 1 (CRM1) in Large Cell Lymphoma von Abeykoon, Jithma P., Hampel, Paul J., King, Rebecca L., Wood, Adam J, Larson, Melissa C., Nowakowski, Kevin E., Zanwar, Saurabh, Ravindran, Aishwarya, Maurer, Matthew J., Wellik, Linda, Paludo, Jonas, Link, Brian K., Cerhan, James R., Wu, Xiaosheng, Habermann, Thomas M., Witzig, Thomas E.

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Salicylates Potentiate and Broaden CRM1 Inhibitor Anti-Tumor Activity Via S-Phase Arrest and Impaired DNA-Damage Repair von Abeykoon, Jithma P., Wu, Xiaosheng, Nowakowski, Kevin E., Dasari, Surendra, Paludo, Jonas, Weroha, S. John, Hu, Chunling, Sarkaria, Jann, Mladek, Ann, Phillips, Jessica, Feldman, Andrew L., Ravindran, Aishwarya, King, Rebecca L., Stenson, Mary J., Manske, Michelle, Couch, Fergus, Patnaik, Mrinal M., Witzig, Thomas E.

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The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders von Willsey, A. Jeremy, Morris, Montana T., Wang, Sheng, Willsey, Helen R., Sun, Nawei, Teerikorpi, Nia, Baum, Tierney B., Cagney, Gerard, Bender, Kevin J., Desai, Tejal A., Srivastava, Deepak, Davis, Graeme W., Doudna, Jennifer, Chang, Edward, Sohal, Vikaas, Lowenstein, Daniel H., Li, Hao, Agard, David, Keiser, Michael J., Shoichet, Brian, von Zastrow, Mark, Mucke, Lennart, Finkbeiner, Steven, Gan, Li, Sestan, Nenad, Ward, Michael E., Huttenhain, Ruth, Nowakowski, Tomasz J., Bellen, Hugo J., Frank, Loren M., Khokha, Mustafa K., Lifton, Richard P., Kampmann, Martin, Ideker, Trey, State, Matthew W., Krogan, Nevan J.

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Fate mapping of neural stem cell niches reveals distinct origins of human cortical astrocytes von Allen, Denise E, Donohue, Kevin C, Cadwell, Cathryn R, Shin, David, Keefe, Matthew G, Sohal, Vikaas S, Nowakowski, Tomasz J

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Tropism of SARS-CoV-2 for human cortical astrocytes von Andrews, Madeline G, Mukhtar, Tanzila, Eze, Ugomma C, Simoneau, Camille R, Ross, Jayden, Parikshak, Neelroop, Wang, Shaohui, Zhou, Li, Koontz, Mark, Velmeshev, Dmitry, Siebert, Clara-Vita, Gemenes, Kaila M, Tabata, Takako, Perez, Yonatan, Wang, Li, Mostajo-Radji, Mohammed A, de Majo, Martina, Donohue, Kevin C, Shin, David, Salma, Jahan, Pollen, Alex A, Nowakowski, Tomasz J, Ullian, Erik, Kumar, G Renuka, Winkler, Ethan A, Crouch, Elizabeth E, Ott, Melanie, Kriegstein, Arnold R

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Group 2 innate lymphoid cells promote inhibitory synapse development and social behavior von Barron, Jerika J, Mroz, Nicholas M, Taloma, Sunrae E, Dahlgren, Madelene W, Ortiz-Carpena, Jorge F, Keefe, Matthew G, Escoubas, Caroline C, Dorman, Leah C, Vainchtein, Ilia D, Chiaranunt, Pailin, Kotas, Maya E, Nowakowski, Tomasz J, Bender, Kevin J, Molofsky, Ari B, Molofsky, Anna V

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Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders von Shin, David, Kim, Chang N., Ross, Jayden, Hennick, Kelsey M., Wu, Sih-Rong, Paranjape, Neha, Leonard, Rachel, Wang, Jerrick C., Keefe, Matthew G., Pavlovic, Bryan J., Donohue, Kevin C., Moreau, Clara, Wigdor, Emilie M., Larson, H. Hanh, Allen, Denise E., Cadwell, Cathryn R., Bhaduri, Aparna, Popova, Galina, Bearden, Carrie E., Pollen, Alex A., Jacquemont, Sebastien, Sanders, Stephan J., Haussler, David, Wiita, Arun P., Frost, Nicholas A., Sohal, Vikaas S., Nowakowski, Tomasz J.

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Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma von Wu, Xiaosheng, Stenson, Mary, Abeykoon, Jithma, Nowakowski, Kevin, Zhang, Lianwen, Lawson, Joshua, Wellik, Linda, Li, Ying, Krull, Jordan, Wenzl, Kerstin, Novak, Anne J., Ansell, Stephen M., Bishop, Gail A., Billadeau, Daniel D., Peng, Kah Whye, Giles, Francis, Schmitt, Daniel M., Witzig, Thomas E.

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Single-cell genomics and regulatory networks for 388 human brains von Emani, Prashant S, Liu, Jason J, Clarke, Declan, Jensen, Matthew, Warrell, Jonathan, Gupta, Chirag, Meng, Ran, Lee, Che Yu, Xu, Siwei, Dursun, Cagatay, Lou, Shaoke, Chen, Yuhang, Chu, Zhiyuan, Galeev, Timur, Hwang, Ahyeon, Li, Yunyang, Ni, Pengyu, Zhou, Xiao, Bakken, Trygve E, Bendl, Jaroslav, Bicks, Lucy, Chatterjee, Tanima, Cheng, Lijun, Cheng, Yuyan, Dai, Yi, Duan, Ziheng, Flaherty, Mary, Fullard, John F, Gancz, Michael, Garrido-Martín, Diego, Gaynor-Gillett, Sophia, Grundman, Jennifer, Hawken, Natalie, Henry, Ella, Hoffman, Gabriel E, Huang, Ao, Jiang, Yunzhe, Jin, Ting, Jorstad, Nikolas L, Kawaguchi, Riki, Khullar, Saniya, Liu, Jianyin, Liu, Junhao, Liu, Shuang, Ma, Shaojie, Margolis, Michael, Mazariegos, Samantha, Moore, Jill, Moran, Jennifer R, Nguyen, Eric, Phalke, Nishigandha, Pjanic, Milos, Pratt, Henry, Quintero, Diana, Rajagopalan, Ananya S, Riesenmy, Tiernon R, Shedd, Nicole, Shi, Manman, Spector, Megan, Terwilliger, Rosemarie, Travaglini, Kyle J, Wamsley, Brie, Wang, Gaoyuan, Xia, Yan, Xiao, Shaohua, Yang, Andrew C, Zheng, Suchen, Gandal, Michael J, Lee, Donghoon, Lein, Ed S, Roussos, Panos, Sestan, Nenad, Weng, Zhiping, White, Kevin P, Won, Hyejung, Girgenti, Matthew J, Zhang, Jing, Wang, Daifeng, Geschwind, Daniel, Gerstein, Mark

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Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas von Witzig, Thomas E., Tang, Hui, Micallef, Ivana N.M., Ansell, Stephen M., Link, Brian K., Inwards, David J., Porrata, Luis F., Johnston, Patrick B., Colgan, Joseph P., Markovic, Svetomir N., Nowakowski, Grzegorz S., Thompson, Carrie A., Allmer, Cristine, Maurer, Matthew J., Gupta, Mamta, Weiner, George, Hohl, Ray, Kurtin, Paul J., Ding, Husheng, Loegering, David, Schneider, Paula, Peterson, Kevin, Habermann, Thomas M., Kaufmann, Scott H.

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Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury von Krenitsky, Véronique Plantevin, Delgado, Mercedes, Nadolny, Lisa, Sahasrabudhe, Kiran, Ayala, Leticia, Clareen, Steven S., Hilgraf, Robert, Albers, Ronald, Kois, Adam, Hughes, Kevin, Wright, Jonathan, Nowakowski, Jacek, Sudbeck, Elise, Ghosh, Sutapa, Bahmanyar, Sogole, Chamberlain, Philip, Muir, Jeff, Cathers, Brian E., Giegel, David, Xu, Li, Celeridad, Maria, Moghaddam, Mehran, Khatsenko, Oleg, Omholt, Paul, Katz, Jason, Pai, Sema, Fan, Rachel, Tang, Yang, Shirley, Michael A., Benish, Brent, Blease, Kate, Raymon, Heather, Bhagwat, Shripad, Henderson, Ian, Cole, Andrew G., Bennett, Brydon, Satoh, Yoshitaka

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