COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis von Chua, Robert Lorenz, Lukassen, Soeren, Trump, Saskia, Hennig, Bianca P., Wendisch, Daniel, Pott, Fabian, Debnath, Olivia, Thürmann, Loreen, Kurth, Florian, Völker, Maria Theresa, Kazmierski, Julia, Timmermann, Bernd, Twardziok, Sven, Schneider, Stefan, Machleidt, Felix, Müller-Redetzky, Holger, Maier, Melanie, Krannich, Alexander, Schmidt, Sein, Balzer, Felix, Liebig, Johannes, Loske, Jennifer, Suttorp, Norbert, Eils, Jürgen, Ishaque, Naveed, Liebert, Uwe Gerd, von Kalle, Christof, Hocke, Andreas, Witzenrath, Martin, Goffinet, Christine, Drosten, Christian, Laudi, Sven, Lehmann, Irina, Conrad, Christian, Sander, Leif-Erik, Eils, Roland

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SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis von Wendisch, Daniel, Dietrich, Oliver, Mari, Tommaso, von Stillfried, Saskia, Ibarra, Ignacio L., Mittermaier, Mirja, Mache, Christin, Chua, Robert Lorenz, Knoll, Rainer, Timm, Sara, Brumhard, Sophia, Krammer, Tobias, Zauber, Henrik, Hiller, Anna Luisa, Pascual-Reguant, Anna, Mothes, Ronja, Bülow, Roman David, Schulze, Jessica, Leipold, Alexander M., Djudjaj, Sonja, Erhard, Florian, Geffers, Robert, Pott, Fabian, Kazmierski, Julia, Radke, Josefine, Pergantis, Panagiotis, Baßler, Kevin, Conrad, Claudia, Aschenbrenner, Anna C., Sawitzki, Birgit, Landthaler, Markus, Wyler, Emanuel, Horst, David, Hippenstiel, Stefan, Hocke, Andreas, Heppner, Frank L., Uhrig, Alexander, Garcia, Carmen, Machleidt, Felix, Herold, Susanne, Elezkurtaj, Sefer, Thibeault, Charlotte, Witzenrath, Martin, Cochain, Clément, Suttorp, Norbert, Drosten, Christian, Goffinet, Christine, Kurth, Florian, Schultze, Joachim L., Radbruch, Helena, Ochs, Matthias, Eils, Roland, Müller-Redetzky, Holger, Hauser, Anja E., Luecken, Malte D., Theis, Fabian J., Conrad, Christian, Wolff, Thorsten, Boor, Peter, Selbach, Matthias, Saliba, Antoine-Emmanuel, Sander, Leif Erik

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Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19 von Nouailles, Geraldine, Wyler, Emanuel, Pennitz, Peter, Postmus, Dylan, Vladimirova, Daria, Kazmierski, Julia, Pott, Fabian, Dietert, Kristina, Muelleder, Michael, Farztdinov, Vadim, Obermayer, Benedikt, Wienhold, Sandra-Maria, Andreotti, Sandro, Hoefler, Thomas, Sawitzki, Birgit, Drosten, Christian, Sander, Leif E., Suttorp, Norbert, Ralser, Markus, Beule, Dieter, Gruber, Achim D., Goffinet, Christine, Landthaler, Markus, Trimpert, Jakob, Witzenrath, Martin

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Recognition of Streptococcus pneumoniae by the innate immune system von Koppe, Uwe, Suttorp, Norbert, Opitz, Bastian

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Ultra-fast proteomics with Scanning SWATH von Messner, Christoph B., Demichev, Vadim, Bloomfield, Nic, Yu, Jason S. L., White, Matthew, Kreidl, Marco, Egger, Anna-Sophia, Freiwald, Anja, Ivosev, Gordana, Wasim, Fras, Zelezniak, Aleksej, Jürgens, Linda, Suttorp, Norbert, Sander, Leif Erik, Kurth, Florian, Lilley, Kathryn S., Mülleder, Michael, Tate, Stephen, Ralser, Markus

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A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model von Kreye, Jakob, Reincke, S. Momsen, Kornau, Hans-Christian, Sánchez-Sendin, Elisa, Corman, Victor Max, Liu, Hejun, Yuan, Meng, Wu, Nicholas C., Zhu, Xueyong, Lee, Chang-Chun D., Trimpert, Jakob, Höltje, Markus, Dietert, Kristina, Stöffler, Laura, von Wardenburg, Niels, van Hoof, Scott, Homeyer, Marie A., Hoffmann, Julius, Abdelgawad, Azza, Gruber, Achim D., Bertzbach, Luca D., Vladimirova, Daria, Li, Lucie Y., Barthel, Paula Charlotte, Skriner, Karl, Hocke, Andreas C., Hippenstiel, Stefan, Witzenrath, Martin, Suttorp, Norbert, Kurth, Florian, Franke, Christiana, Endres, Matthias, Schmitz, Dietmar, Jeworowski, Lara Maria, Richter, Anja, Schmidt, Marie Luisa, Schwarz, Tatjana, Müller, Marcel Alexander, Drosten, Christian, Wendisch, Daniel, Sander, Leif E., Osterrieder, Nikolaus, Wilson, Ian A., Prüss, Harald

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Innate Immune Recognition in Infectious and Noninfectious Diseases of the Lung von OPITZ, Bastian, VAN LAAK, Vincent, EITEL, Julia

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Heterogeneous approach to nebulization of antimicrobial agents in mechanically ventilated adults in a German tertiary care hospital: a cross-sectional survey von Pfäfflin, Frieder, Stegemann, Miriam, Suttorp, Norbert, Uhrig, Alexander, Achterberg, Stephan

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Role of Toll-like receptors, NOD-like receptors and RIG-I-like receptors in endothelial cells and systemic infections von Opitz, Bastian, Eitel, Julia, Meixenberger, Karolin, Suttorp, Norbert

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IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid von Naujoks, Jan, Tabeling, Christoph, Dill, Brian D, Hoffmann, Christine, Brown, Andrew S, Kunze, Mareike, Kempa, Stefan, Peter, Andrea, Mollenkopf, Hans-Joachim, Dorhoi, Anca, Kershaw, Olivia, Gruber, Achim D, Sander, Leif E, Witzenrath, Martin, Herold, Susanne, Nerlich, Andreas, Hocke, Andreas C, van Driel, Ian, Suttorp, Norbert, Bedoui, Sammy, Hilbi, Hubert, Trost, Matthias, Opitz, Bastian

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Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany von Schwarz, Tatjana, Tober-Lau, Pinkus, Hillus, David, Helbig, Elisa T, Lippert, Lena J, Thibeault, Charlotte, Koch, Willi, Landgraf, Irmgard, Michel, Janine, Bergfeld, Leon, Niemeyer, Daniela, Muhlemann, Barbara, Conrad, Claudia, Dang-Heine, Chantip, Kasper, Stefanie, Munn, Friederike, Kappert, Kai, Nitsche, Andreas, Tauber, Rudolf, Schmidt, Sein, Kopankiewicz, Piotr, Bias, Harald, Seybold, Joachim, von Kalle, Christof, Jones, Terry C, Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Corman, Victor M, Kurth, Florian

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A biomathematical model of atherosclerosis in mice von Schirm, Sibylle, Haghikia, Arash, Brack, Markus, Ahnert, Peter, Nouailles, Geraldine, Suttorp, Norbert, Loeffler, Markus, Witzenrath, Martin, Scholz, Markus

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Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages von Hönzke, Katja, Obermayer, Benedikt, Mache, Christin, Fathykova, Diana, Kessler, Mirjana, Dökel, Simon, Wyler, Emanuel, Baumgardt, Morris, Löwa, Anna, Hoffmann, Karen, Graff, Patrick, Schulze, Jessica, Mieth, Maren, Hellwig, Katharina, Demir, Zeynep, Biere, Barbara, Brunotte, Linda, Mecate-Zambrano, Angeles, Bushe, Judith, Dohmen, Melanie, Hinze, Christian, Elezkurtaj, Sefer, Tönnies, Mario, Bauer, Torsten T, Eggeling, Stephan, Tran, Hong-Linh, Schneider, Paul, Neudecker, Jens, Rückert, Jens C, Schmidt-Ott, Kai M, Busch, Jonas, Klauschen, Frederick, Horst, David, Radbruch, Helena, Radke, Josefine, Heppner, Frank, Corman, Victor M, Niemeyer, Daniela, Müller, Marcel A, Goffinet, Christine, Mothes, Ronja, Pascual-Reguant, Anna, Hauser, Anja Erika, Beule, Dieter, Landthaler, Markus, Ludwig, Stephan, Suttorp, Norbert, Witzenrath, Martin, Gruber, Achim D, Drosten, Christian, Sander, Leif-Erik, Wolff, Thorsten, Hippenstiel, Stefan, Hocke, Andreas C

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Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections von Tober-Lau, Pinkus, Gruell, Henning, Vanshylla, Kanika, Koch, Willi M, Hillus, David, Schommers, Philipp, Suárez, Isabelle, Suttorp, Norbert, Sander, Leif Erik, Klein, Florian, Kurth, Florian

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The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia von Witzenrath, Martin, Pache, Florence, Lorenz, Daniel, Koppe, Uwe, Gutbier, Birgitt, Tabeling, Christoph, Reppe, Katrin, Meixenberger, Karolin, Dorhoi, Anca, Ma, Jiangtao, Holmes, Ashleigh, Trendelenburg, George, Heimesaat, Markus M, Bereswill, Stefan, van der Linden, Mark, Tschopp, Jürg, Mitchell, Timothy J, Suttorp, Norbert, Opitz, Bastian

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Preparing for patients with high-consequence infectious diseases: Example of a high-level isolation unit von Pfäfflin, Frieder, Stegemann, Miriam Songa, Heim, Katrin Moira, Achterberg, Stephan, Pfitzner, Ursula, Götze, Louise, Oesterhelweg, Lars, Suttorp, Norbert, Herzog, Christian, Stadtmann, Benjamin, Uhrig, Alexander

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Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives von Müller-Redetzky, Holger C, Suttorp, Norbert, Witzenrath, Martin

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Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia von Dietert, Kristina, Gutbier, Birgitt, Wienhold, Sandra M, Reppe, Katrin, Jiang, Xiaohui, Yao, Ling, Chaput, Catherine, Naujoks, Jan, Brack, Markus, Kupke, Alexandra, Peteranderl, Christin, Becker, Stephan, von Lachner, Carolin, Baal, Nelli, Slevogt, Hortense, Hocke, Andreas C, Witzenrath, Martin, Opitz, Bastian, Herold, Susanne, Hackstein, Holger, Sander, Leif E, Suttorp, Norbert, Gruber, Achim D

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CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction von Tabeling, Christoph, Yu, Hanpo, Wang, Liming, Ranke, Hannes, Goldenberg, Neil M., Zabini, Diana, Noe, Elena, Krauszman, Adrienn, Gutbier, Birgitt, Yin, Jun, Schaefer, Michael, Arenz, Christoph, Hocke, Andreas C., Suttorp, Norbert, Proia, Richard L., Witzenrath, Martin, Kuebler, Wolfgang M.

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Tyk2 as a target for immune regulation in human viral/bacterial pneumonia von Berg, Johanna, Zscheppang, Katja, Fatykhova, Diana, Tönnies, Mario, Bauer, Torsten T, Schneider, Paul, Neudecker, Jens, Rückert, Jens C, Eggeling, Stephan, Schimek, Maria, Gruber, Achim D, Suttorp, Norbert, Hippenstiel, Stefan, Hocke, Andreas C

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