Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits von Porcu, Eleonora, Rüeger, Sina, Lepik, Kaido, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán

Volltext

Genetic and environmental influences interact with age and sex in shaping the human methylome von van Dongen, Jenny, Nivard, Michel G., Willemsen, Gonneke, Hottenga, Jouke-Jan, Helmer, Quinta, Dolan, Conor V., Ehli, Erik A., Davies, Gareth E., van Iterson, Maarten, Breeze, Charles E., Beck, Stephan, Suchiman, H. Eka, Jansen, Rick, van Meurs, Joyce B., Heijmans, Bastiaan T., Slagboom, P. Eline, Boomsma, Dorret I.

Volltext

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation von Richard, Melissa A., Huan, Tianxiao, Ligthart, Symen, Gondalia, Rahul, Jhun, Min A., Brody, Jennifer A., Irvin, Marguerite R., Montasser, May E., Jia, Yucheng, Syme, Catriona, Salfati, Elias L., Boerwinkle, Eric, Guan, Weihua, Mosley, Thomas H., Bressler, Jan, Morrison, Alanna C., Liu, Chunyu, Mendelson, Michael M., Uitterlinden, André G., van Meurs, Joyce B., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Franke, Lude, Boomsma, Dorret I., Pool, René, Hottenga, Jouke J., van Greevenbroek, Marleen M.J., Stehouwer, Coen D.A., Wijmenga, Cisca, Zhernakova, Alexandra, Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Albert, Uitterlinden, André G., Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Nooren, Irene, Moed, Matthijs, Vermaat, Martijn, Zhernakova, Dasha V., Luijk, René, Bonder, Marc Jan, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik W., Franco, Oscar H., Zhang, Guosheng, Li, Yun, Stewart, James D., Bis, Joshua C., Psaty, Bruce M., Chen, Yii-Der Ida, Kardia, Sharon L.R., Zhao, Wei, Absher, Devin, Aslibekyan, Stella, Starr, John M., McRae, Allan F., Schwartz, Joel D., Vokonas, Pantel S., Menni, Cristina, Spector, Tim D., Shuldiner, Alan, Damcott, Coleen M., Rotter, Jerome I., Palmas, Walter, Liu, Yongmei, Paus, Tomáš, Horvath, Steve, O’Connell, Jeffrey R., Guo, Xiuqing, Pausova, Zdenka, Assimes, Themistocles L., Sotoodehnia, Nona, Smith, Jennifer A., Arnett, Donna K., Deary, Ian J., Baccarelli, Andrea A., Bell, Jordana T., Whitsel, Eric, Dehghan, Abbas, Levy, Daniel, Fornage, Myriam

Volltext

A linear mixed-model approach to study multivariate gene–environment interactions von Moore, Rachel, Casale, Francesco Paolo, Jan Bonder, Marc, Horta, Danilo, Franke, Lude, Barroso, Inês, Stegle, Oliver

Volltext

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults von van Dongen, Jenny, Zilhão, Nuno R., Sugden, Karen, Heijmans, Bastiaan T., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Jansen, Rick, Franke, Lude, Boomsma, Dorret I., Pool, René, van Dongen, Jenny, Hottenga, Jouke J., van Greevenbroek, Marleen M.J., Stehouwer, Coen D.A., van der Kallen, Carla J.H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Uitterlinden, André G., van Meurs, Joyce, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha V., Hof, Peter van ’t, Deelen, Patrick, Nooren, Irene, Heijmans, Bastiaan T., Moed, Matthijs, Franke, Lude, Vermaat, Martijn, Luijk, René, Bonder, Marc Jan, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik. W., Hoen, Peter-Bram ’t, Heijmans, Bastiaan T., Hannon, Eilis J., Mill, Jonathan, Caspi, Avshalom, Agnew-Blais, Jessica, Arseneault, Louise, Corcoran, David L., Moffitt, Terrie E., Poulton, Richie, Franke, Barbara, Boomsma, Dorret I.

Volltext

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations von Shah, Sonia, Bonder, Marc J., Marioni, Riccardo E., Zhu, Zhihong, McRae, Allan F., Zhernakova, Alexandra, Harris, Sarah E., Liewald, Dave, Henders, Anjali K., Mendelson, Michael M., Liu, Chunyu, Joehanes, Roby, Liang, Liming, Heijmans, Bastiaan T., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Jansen, Rick, Franke, Lude, Boomsma, Dorret I., Pool, René, van Dongen, Jenny, Hottenga, Jouke J., van Greevenbroek, Marleen M.J., Stehouwer, Coen D.A., van der Kallen, Carla J.H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Uitterlinden, André G., Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, van ’t Hof, Peter, Deelen, Patrick, Nooren, Irene, Moed, Matthijs, Vermaat, Martijn, Zhernakova, Dasha V., Luijk, René, Bonder, Marc Jan, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik W., Levy, Daniel, Martin, Nicholas G., Starr, John M., Wijmenga, Cisca, Wray, Naomi R., Yang, Jian, Montgomery, Grant W., Franke, Lude, Deary, Ian J., Visscher, Peter M.

Volltext

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan von van Dongen, Jenny, Hagenbeek, Fiona A., Suderman, Matthew, Roetman, Peter J., Sugden, Karen, Chiocchetti, Andreas G., Ismail, Khadeeja, Mulder, Rosa H., Hafferty, Jonathan D., Adams, Mark J., Walker, Rosie M., Morris, Stewart W., Lahti, Jari, Küpers, Leanne K., Escaramis, Georgia, Alemany, Silvia, Jan Bonder, Marc, Meijer, Mandy, Ip, Hill F., Jansen, Rick, Baselmans, Bart M. L., Parmar, Priyanka, Lowry, Estelle, Streit, Fabian, Sirignano, Lea, Send, Tabea S., Frank, Josef, Jylhävä, Juulia, Wang, Yunzhang, Mishra, Pashupati Prasad, Colins, Olivier F., Corcoran, David L., Poulton, Richie, Mill, Jonathan, Hannon, Eilis, Arseneault, Louise, Korhonen, Tellervo, Vuoksimaa, Eero, Felix, Janine F., Bakermans-Kranenburg, Marian J., Campbell, Archie, Czamara, Darina, Binder, Elisabeth, Corpeleijn, Eva, Gonzalez, Juan R., Grazuleviciene, Regina, Gutzkow, Kristine B., Evandt, Jorunn, Vafeiadi, Marina, Klein, Marieke, van der Meer, Dennis, Ligthart, Lannie, Kluft, Cornelis, Davies, Gareth E., Hakulinen, Christian, Keltikangas-Järvinen, Liisa, Franke, Barbara, Freitag, Christine M., Konrad, Kerstin, Hervas, Amaia, Fernández-Rivas, Aranzazu, Vetro, Agnes, Raitakari, Olli, Lehtimäki, Terho, Vermeiren, Robert, Strandberg, Timo, Räikkönen, Katri, Snieder, Harold, Witt, Stephanie H., Deuschle, Michael, Pedersen, Nancy L., Hägg, Sara, Sunyer, Jordi, Franke, Lude, Kaprio, Jaakko, Ollikainen, Miina, Moffitt, Terrie E., Tiemeier, Henning, van IJzendoorn, Marinus H., Relton, Caroline, Vrijheid, Martine, Sebert, Sylvain, Jarvelin, Marjo-Riitta, Caspi, Avshalom, Evans, Kathryn L., McIntosh, Andrew M., Bartels, Meike, Boomsma, Dorret I.

Volltext

A SNP panel for identification of DNA and RNA specimens von Yousefi, Soheil, Abbassi-Daloii, Tooba, Kraaijenbrink, Thirsa, Vermaat, Martijn, Mei, Hailiang, van 't Hof, Peter, van Iterson, Maarten, Zhernakova, Daria V, Claringbould, Annique, Franke, Lude, 't Hart, Leen M, Slieker, Roderick C, van der Heijden, Amber, de Knijff, Peter, 't Hoen, Peter A C

Volltext

DNA methylation in peripheral tissues and left-handedness von Odintsova, Veronika V., Suderman, Matthew, Hagenbeek, Fiona A., Caramaschi, Doretta, Hottenga, Jouke-Jan, Pool, René, Dolan, Conor V., Ligthart, Lannie, van Beijsterveldt, Catharina E. M., Willemsen, Gonneke, de Geus, Eco J. C., Beck, Jeffrey J., Ehli, Erik A., Cuellar-Partida, Gabriel, Evans, David M., Medland, Sarah E., Relton, Caroline L., Boomsma, Dorret I., van Dongen, Jenny

Volltext

A characterization of cis- and trans-heritability of RNA-Seq-based gene expression von Ouwens, Klaasjan G, Jansen, Rick, Nivard, Michel G, van Dongen, Jenny, Frieser, Maia J, Hottenga, Jouke-Jan, Arindrarto, Wibowo, Claringbould, Annique, van Iterson, Maarten, Mei, Hailiang, Franke, Lude, Heijmans, Bastiaan T, A C 't Hoen, Peter, van Meurs, Joyce, Brooks, Andrew I, Penninx, Brenda W J H, Boomsma, Dorret I

Volltext

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs von Ricaño-Ponce, Isis, Zhernakova, Daria V, Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M, Gutierrez-Achury, Javier, Uitterlinden, Andre G, Hofman, Albert, van Meurs, Joyce, Netea, Mihai G, Jonkers, Iris H, Withoff, Sebo, van Duijn, Cornelia M, Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod

Volltext

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation von Luijk, René, Wu, Haoyu, Ward-Caviness, Cavin K, Hannon, Eilis, Carnero-Montoro, Elena, Min, Josine L., Mandaviya, Pooja, Müller-Nurasyid, Martina, Mei, Hailiang, van der Maarel, Silvere M., Relton, Caroline, Mill, Jonathan, Waldenberger, Melanie, Bell, Jordana T., Jansen, Rick, Zhernakova, Alexandra, Franke, Lude, ‘t Hoen, Peter A. C., Boomsma, Dorret I., van Duijn, Cornelia M., van Greevenbroek, Marleen M. J., Veldink, Jan H., Wijmenga, Cisca, van Meurs, Joyce, Daxinger, Lucia, Slagboom, P. Eline, van Zwet, Erik W., Heijmans, Bastiaan T.

Volltext

Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes von Ligthart, Symen, Steenaard, Rebecca V., Peters, Marjolein J., van Meurs, Joyce B. J., Sijbrands, Eric J. G., Uitterlinden, André G., Bonder, Marc J., Hofman, Albert, Franco, Oscar H., Dehghan, Abbas

Volltext

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression von van der Plaat, Diana A, Vonk, Judith M, Terzikhan, Natalie, de Jong, Kim, de Vries, Maaike, La Bastide-van Gemert, Sacha, van Diemen, Cleo C, Lahousse, Lies, Brusselle, Guy G, Nedeljkovic, Ivana, Amin, Najaf, Kromhout, Hans, Vermeulen, Roel C H, Postma, Dirkje S, van Duijn, Cornelia M, Boezen, H Marike

Volltext

Correction for both common and rare cell types in blood is important to identify genes that correlate with age von Pellegrino-Coppola, Damiano, Claringbould, Annique, Stutvoet, Maartje, Boomsma, Dorret I, Ikram, M Arfan, Slagboom, P Eline, Westra, Harm-Jan, Franke, Lude

Volltext

Genome-wide identification of directed gene networks using large-scale population genomics data von Luijk, René, Dekkers, Koen F., van Iterson, Maarten, Arindrarto, Wibowo, Claringbould, Annique, Hop, Paul, Boomsma, Dorret I., van Duijn, Cornelia M., van Greevenbroek, Marleen M. J., Veldink, Jan H., Wijmenga, Cisca, Franke, Lude, ’t Hoen, Peter A. C., Jansen, Rick, van Meurs, Joyce, Mei, Hailiang, Slagboom, P. Eline, Heijmans, Bastiaan T., van Zwet, Erik W.

Volltext

Comprehensive evaluation of smoking exposures and their interactions on DNA methylation von Hoang, Thanh T., Lee, Yunsung, McCartney, Daniel L., Kersten, Elin T.G., Page, Christian M., Hulls, Paige M., Lee, Mikyeong, Walker, Rosie M., Breeze, Charles E., Bennett, Brian D., Burkholder, Adam B., Ward, James, Brantsæter, Anne Lise, Caspersen, Ida H., Motsinger-Reif, Alison A., Richards, Marie, White, Julie D., Zhao, Shanshan, Richmond, Rebecca C., Magnus, Maria C., Heijmans, Bastiaan, ’t Hoen, Peter, van Meurs, Joyce, Jansen, Rick, Franke, Lude, Boomsma, Dorret, Pool, René, van Dongen, Jenny, Hottenga, Jouke, van Greevenbroek, Marleen, Stehouwer, Coen, van der Kallen, Carla, Schalkwijk, Casper, Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje, Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, Van Heemst, Diana, Veldink, Jan, van den Berg, Leonard, van Duijn, Cornelia, Hofman, Bert, Isaacs, Aaron, Uitterlinden, André, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka, Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha, van ‘t Hof, Peter, Deelen, Patrick, Nooren, Irene, Moed, Matthijs, Vermaat, Martijn, Luijk, René, Bonder, Marc, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon, Swertz, Morris, van Zwet, Erik, Koppelman, Gerard H., Evans, Kathryn L., Marioni, Riccardo E., Håberg, Siri E., London, Stephanie J.

Volltext

The tetramerization domain of the Mnt repressor consists of two right-handed coiled coils von Boelens, Rolf, Nooren, Irene M.A, Kaptein, Robert, Sauer, Robert T

Volltext

Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data von van Hilten, Arno, van Rooij, Jeroen, Ikram, M. Arfan, Niessen, Wiro J., van Meurs, Joyce. B. J., Roshchupkin, Gennady V.

Volltext

DNA methylation signatures of educational attainment von van Dongen, Jenny, Bonder, Marc Jan, Dekkers, Koen F., Nivard, Michel G., van Iterson, Maarten, Willemsen, Gonneke, Beekman, Marian, van der Spek, Ashley, van Meurs, Joyce B. J., Franke, Lude, Heijmans, Bastiaan T., van Duijn, Cornelia M., Slagboom, P. Eline, Boomsma, Dorret I.

Volltext