Dip1 Defines a Class of Arp2/3 Complex Activators that Function without Preformed Actin Filaments von Wagner, Andrew R., Luan, Qing, Liu, Su-Ling, Nolen, Brad J.

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Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP von Helgeson, Luke A, Nolen, Brad J

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Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex von Rodnick-Smith, Max, Luan, Qing, Liu, Su-Ling, Nolen, Brad J.

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Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex von Rodnick-Smith, Max, Liu, Su-Ling, Balzer, Connor J., Luan, Qing, Nolen, Brad J.

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The intrinsically disordered cytoplasmic tail of a dendrite branching receptor uses two distinct mechanisms to regulate the actin cytoskeleton von Kramer, Daniel A, Narvaez-Ortiz, Heidy Y, Patel, Urval, Shi, Rebecca, Shen, Kang, Nolen, Brad J, Roche, Julien, Chen, Baoyu

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Synergy between Wsp1 and Dip1 may initiate assembly of endocytic actin networks von Balzer, Connor J., James, Michael L., Narvaez-Ortiz, Heidy Y., Helgeson, Luke A., Sirotkin, Vladimir, Nolen, Brad J.

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Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state von Shaaban, Mohammed, Chowdhury, Saikat, Nolen, Brad J.

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Unconcerted conformational changes in Arp2/3 complex integrate multiple activating signals to assemble functional actin networks von Narvaez-Ortiz, Heidy Y., Nolen, Brad J.

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Molecular dynamics simulations support a multistep pathway for activation of branched actin filament nucleation by Arp2/3 complex von Singh, Yuvraj, Hocky, Glen M., Nolen, Brad J.

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Structural basis for regulation of Arp2/3 complex by GMF von Luan, Qing, Nolen, Brad J

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Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy von Ding, Bojian, Narvaez-Ortiz, Heidy Y, Singh, Yuvraj, Hocky, Glen M, Chowdhury, Saikat, Nolen, Brad J

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Structure and Biochemical Properties of Fission Yeast Arp2/3 Complex Lacking the Arp2 Subunit von Nolen, Brad J., Pollard, Thomas D.

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Nucleotide-Mediated Conformational Changes of Monomeric Actin and Arp3 Studied by Molecular Dynamics Simulations von Dalhaimer, Paul, Pollard, Thomas D., Nolen, Brad J.

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Both Las17-binding sites on Arp2/3 complex are important for branching nucleation and assembly of functional endocytic actin networks in S. cerevisiae von Narvaez-Ortiz, Heidy Y., Lynch, Michael J., Liu, Su-Ling, Fries, Adam, Nolen, Brad J.

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Structure of the nucleation‐promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex von Luan, Qing, Liu, Su‐Ling, Helgeson, Luke A, Nolen, Brad J

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Single-Turnover Activation of Arp2/3 Complex by Dip1 May Balance Nucleation of Linear versus Branched Actin Filaments von Balzer, Connor J., Wagner, Andrew R., Helgeson, Luke A., Nolen, Brad J.

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Identification of Wiskott-Aldrich syndrome protein (WASP) binding sites on the branched actin filament nucleator Arp2/3 complex von Luan, Qing, Zelter, Alex, MacCoss, Michael J., Davis, Trisha N., Nolen, Brad J.

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Small Molecules CK-666 and CK-869 Inhibit Actin-Related Protein 2/3 Complex by Blocking an Activating Conformational Change von Hetrick, Byron, Han, Min Suk, Helgeson, Luke A., Nolen, Brad J.

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Crystal Structures of Actin-Related Protein 2/3 Complex with Bound ATP or ADP von Nolen, Brad J., Littlefield, Ryan S., Pollard, Thomas D.

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Dip1 Co-opts Features of Branching Nucleation to Create Linear Actin Filaments that Activate WASP-Bound Arp2/3 Complex von Balzer, Connor J., Wagner, Andrew R., Helgeson, Luke A., Nolen, Brad J.

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