Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state von Shaaban, Mohammed, Chowdhury, Saikat, Nolen, Brad J.

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Unconcerted conformational changes in Arp2/3 complex integrate multiple activating signals to assemble functional actin networks von Narvaez-Ortiz, Heidy Y., Nolen, Brad J.

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Molecular dynamics simulations support a multistep pathway for activation of branched actin filament nucleation by Arp2/3 complex von Singh, Yuvraj, Hocky, Glen M., Nolen, Brad J.

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Dip1 Defines a Class of Arp2/3 Complex Activators that Function without Preformed Actin Filaments von Wagner, Andrew R., Luan, Qing, Liu, Su-Ling, Nolen, Brad J.

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Structural basis for regulation of Arp2/3 complex by GMF von Luan, Qing, Nolen, Brad J

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Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy von Ding, Bojian, Narvaez-Ortiz, Heidy Y, Singh, Yuvraj, Hocky, Glen M, Chowdhury, Saikat, Nolen, Brad J

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Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP von Helgeson, Luke A, Nolen, Brad J

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Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex von Rodnick-Smith, Max, Luan, Qing, Liu, Su-Ling, Nolen, Brad J.

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Both Las17-binding sites on Arp2/3 complex are important for branching nucleation and assembly of functional endocytic actin networks in S. cerevisiae von Narvaez-Ortiz, Heidy Y., Lynch, Michael J., Liu, Su-Ling, Fries, Adam, Nolen, Brad J.

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Structure of the nucleation‐promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex von Luan, Qing, Liu, Su‐Ling, Helgeson, Luke A, Nolen, Brad J

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Single-Turnover Activation of Arp2/3 Complex by Dip1 May Balance Nucleation of Linear versus Branched Actin Filaments von Balzer, Connor J., Wagner, Andrew R., Helgeson, Luke A., Nolen, Brad J.

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Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex von Rodnick-Smith, Max, Liu, Su-Ling, Balzer, Connor J., Luan, Qing, Nolen, Brad J.

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Identification of Wiskott-Aldrich syndrome protein (WASP) binding sites on the branched actin filament nucleator Arp2/3 complex von Luan, Qing, Zelter, Alex, MacCoss, Michael J., Davis, Trisha N., Nolen, Brad J.

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The intrinsically disordered cytoplasmic tail of a dendrite branching receptor uses two distinct mechanisms to regulate the actin cytoskeleton von Kramer, Daniel A, Narvaez-Ortiz, Heidy Y, Patel, Urval, Shi, Rebecca, Shen, Kang, Nolen, Brad J, Roche, Julien, Chen, Baoyu

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Interactions with Actin Monomers, Actin Filaments, and Arp2/3 Complex Define the Roles of WASP Family Proteins and Cortactin in Coordinately Regulating Branched Actin Networks von Helgeson, Luke A., Prendergast, Julianna G., Wagner, Andrew R., Rodnick-Smith, Max, Nolen, Brad J.

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Dip1 Co-opts Features of Branching Nucleation to Create Linear Actin Filaments that Activate WASP-Bound Arp2/3 Complex von Balzer, Connor J., Wagner, Andrew R., Helgeson, Luke A., Nolen, Brad J.

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Improved Analysis of Cross-Linking Mass Spectrometry Data with Kojak 2.0, Advanced by Integration into the Trans-Proteomic Pipeline von Hoopmann, Michael R., Shteynberg, David D., Zelter, Alex, Riffle, Michael, Lyon, Andrew S., Agard, David A., Luan, Qing, Nolen, Brad J., MacCoss, Michael J., Davis, Trisha N., Moritz, Robert L.

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Analysis of functional surfaces on the actin nucleation promoting factor Dip1 required for Arp2/3 complex activation and endocytic actin network assembly von Liu, Su-Ling, Narvaez-Ortiz, Heidy Y., Miner, Matt, Kiemel, Jack, Oberhelman, Nicholas, Watt, April, Wagner, Andrew R., Luan, Qing, Helgeson, Luke A., Nolen, Brad J.

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Synergy between Wsp1 and Dip1 may initiate assembly of endocytic actin networks von Balzer, Connor J., James, Michael L., Narvaez-Ortiz, Heidy Y., Helgeson, Luke A., Sirotkin, Vladimir, Nolen, Brad J.

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Mechanism of a Concentration-dependent Switch between Activation and Inhibition of Arp2/3 Complex by Coronin von Liu, Su-Ling, Needham, Karen M., May, Jordan R., Nolen, Brad J.

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