Age-Dependent Association between Pulmonary Tuberculosis and Common TOX Variants in the 8q12–13 Linkage Region von Grant, Audrey V., El Baghdadi, Jamila, Sabri, Ayoub, El Azbaoui, Safa, Alaoui-Tahiri, Kebir, Abderrahmani Rhorfi, Ismail, Gharbaoui, Yasser, Abid, Ahmed, Benkirane, Majid, Raharimanga, Vaomalala, Richard, Vincent, Orlova, Marianna, Boland, Anne, Migaud, Mélanie, Okada, Satoshi, Nolan, Daniel K., Bustamante, Jacinta, Barreiro, Luis B., Schurr, Erwin, Boisson-Dupuis, Stephanie, Rasolofo, Voahangy, Casanova, Jean-Laurent, Abel, Laurent

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Correlation of Intergenerational Family Sizes Suggests a Genetic Component of Reproductive Fitness von Pluzhnikov, Anna, Nolan, Daniel K., Tan, Zhiqiang, McPeek, Mary Sara, Ober, Carole

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Hypomorphic alleles pose challenges in rare disease genomic variant interpretation von Nolan, Daniel K., Chaudhari, Bimal, Franklin, Samuel J., Wijeratne, Saranga, Pfau, Ruthann, Mihalic Mosher, Theresa, Crist, Erin, McBride, Kim L., White, Peter, Wilson, Richard K., Hickey, Scott E., Koboldt, Daniel C.

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Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene von Singh, Abanish, Babyak, Michael A, Nolan, Daniel K, Brummett, Beverly H, Jiang, Rong, Siegler, Ilene C, Kraus, William E, Shah, Svati H, Williams, Redford B, Hauser, Elizabeth R

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Accounting for genetic heterogeneity in homozygosity mapping: application to Mendelian susceptibility to mycobacterial disease von Grant, Audrey V, Boisson-Dupuis, Stéphanie, Herquelot, Eléonore, de Beaucoudrey, Ludovic, Filipe-Santos, Orchidée, Nolan, Daniel K, Feinberg, Jacqueline, Boland, Anne, Al-Muhsen, Saleh, Sanal, Ozden, Camcioglu, Yildiz, Palanduz, Ayse, Kilic, Sara Sebnem, Bustamante, Jacinta, Casanova, Jean-Laurent, Abel, Laurent

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Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5 von Nolan, Daniel K, Sutton, Beth, Haynes, Carol, Johnson, Jessica, Sebek, Jacqueline, Dowdy, Elaine, Crosslin, David, Crossman, David, Sketch, Jr, Michael H, Granger, Christopher B, Seo, David, Goldschmidt-Clermont, Pascal, Kraus, William E, Gregory, Simon G, Hauser, Elizabeth R, Shah, Svati H

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Hypomorphic alleles pose challenges in rare disease genomic variant interpretation von Nolan, Daniel K, Chaudhari, Bimal, Franklin, Samuel J, Wijeratne, Saranga, Pfau, Ruthann, Mihalic Mosher, Theresa, Crist, Erin, McBride, Kim L, White, Peter, Wilson, Richard K, Hickey, Scott E, Koboldt, Daniel C

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Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development von Bendall, Sean C., Davis, Kara L., Amir, El-ad David, Tadmor, Michelle D., Simonds, Erin F., Chen, Tiffany J., Shenfeld, Daniel K., Nolan, Garry P., Pe’er, Dana

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Organization of the human intestine at single-cell resolution von Hickey, John W., Becker, Winston R., Nevins, Stephanie A., Horning, Aaron, Perez, Almudena Espin, Zhu, Chenchen, Zhu, Bokai, Wei, Bei, Chiu, Roxanne, Chen, Derek C., Cotter, Daniel L., Esplin, Edward D., Weimer, Annika K., Caraccio, Chiara, Venkataraaman, Vishal, Schürch, Christian M., Black, Sarah, Brbić, Maria, Cao, Kaidi, Chen, Shuxiao, Zhang, Weiruo, Monte, Emma, Zhang, Nancy R., Ma, Zongming, Leskovec, Jure, Zhang, Zhengyan, Lin, Shin, Longacre, Teri, Plevritis, Sylvia K., Lin, Yiing, Nolan, Garry P., Greenleaf, William J., Snyder, Michael

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mcr-1 identified in Avian Pathogenic Escherichia coli (APEC) von Lima Barbieri, Nicolle, Nielsen, Daniel W, Wannemuehler, Yvonne, Cavender, Tia, Hussein, Ashraf, Yan, Shi-Gan, Nolan, Lisa K, Logue, Catherine M

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viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia von Amir, El-ad David, Davis, Kara L, Tadmor, Michelle D, Simonds, Erin F, Levine, Jacob H, Bendall, Sean C, Shenfeld, Daniel K, Krishnaswamy, Smita, Nolan, Garry P, Pe'er, Dana

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Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man von Wu, Hemmings, Miller, Kai J., Blumenfeld, Zack, Williams, Nolan R., Ravikumar, Vinod K., Lee, Karen E., Kakusa, Bina, Sacchet, Matthew D., Wintermark, Max, Christoffel, Daniel J., Rutt, Brian K., Bronte-Stewart, Helen, Knutson, Brian, Malenka, Robert C., Halpern, Casey H.

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Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells von Butler, Jason M, Chiu, Vi K, Benjamin, Laura, Rafii, Shahin, Bonner, Bryant, Nolan, Daniel J, Kobayashi, Mariko, Ding, Bi-Sen, O'Donnell, Rebekah, Shido, Koji, Kobayashi, Hideki

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Reversal of emphysema by restoration of pulmonary endothelial cells von Hisata, Shu, Racanelli, Alexandra C, Kermani, Pouneh, Schreiner, Ryan, Houghton, Sean, Palikuqi, Brisa, Kunar, Balvir, Zhou, Aiyuan, McConn, Keith, Capili, Allyson, Redmond, David, Nolan, Daniel J, Ginsberg, Michael, Ding, Bi-Sen, Martinez, Fernando J, Scandura, Joseph M, Cloonan, Suzanne M, Rafii, Shahin, Choi, Augustine M K

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Trait selection and community weighting are key to understanding ecosystem responses to changing precipitation regimes von Griffin-Nolan, Robert J., Bushey, Julie A., Carroll, Charles J. W., Challis, Anthea, Chieppa, Jeff, Garbowski, Magda, Hoffman, Ava M., Post, Alison K., Slette, Ingrid J., Spitzer, Daniel, Zambonini, Dario, Ocheltree, Troy W., Tissue, David T., Knapp, Alan K.

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Modified granular impact force laws for the OSIRIS-REx touchdown on the surface of asteroid (101955) Bennu von Ballouz, R-L, Walsh, K J, Sánchez, P, Holsapple, K A, Michel, P, Scheeres, D J, Zhang, Y, Richardson, D C, Barnouin, O S, Nolan, M C, Bierhaus, E B, Connolly, H C, Schwartz, S R, Çelik, O, Baba, M, Lauretta, D S

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RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers von Nolan, Emma, Vaillant, François, Branstetter, Daniel, Pal, Bhupinder, Giner, Göknur, Whitehead, Lachlan, Lok, Sheau W, Mann, Gregory B, Rohrbach, Kathy, Huang, Li-Ya, Soriano, Rosalia, Smyth, Gordon K, Dougall, William C, Visvader, Jane E, Lindeman, Geoffrey J

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Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments von Pestrak, Matthew J, Chaney, Sarah B, Eggleston, Heather C, Dellos-Nolan, Sheri, Dixit, Sriteja, Mathew-Steiner, Shomita S, Roy, Sashwati, Parsek, Matthew R, Sen, Chandan K, Wozniak, Daniel J

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Mass cytometry analysis reveals hyperactive NF Kappa B signaling in myelofibrosis and secondary acute myeloid leukemia von Fisher, D A C, Malkova, O, Engle, E K, Miner, C A, Fulbright, M C, Behbehani, G K, Collins, T B, Bandyopadhyay, S, Zhou, A, Nolan, G P, Oh, S T

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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors von Replogle, Joseph M, Bonnar, Jessica L, Pogson, Angela N, Liem, Christina R, Maier, Nolan K, Ding, Yufang, Russell, Baylee J, Wang, Xingren, Leng, Kun, Guna, Alina, Norman, Thomas M, Pak, Ryan A, Ramos, Daniel M, Ward, Michael E, Gilbert, Luke A, Kampmann, Martin, Weissman, Jonathan S, Jost, Marco

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