PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis von Yu, Kwanha, Lin, Chia-Ching John, Hatcher, Asante, Lozzi, Brittney, Kong, Kathleen, Huang-Hobbs, Emmet, Cheng, Yi-Ting, Beechar, Vivek B., Zhu, Wenyi, Zhang, Yiqun, Chen, Fengju, Mills, Gordon B., Mohila, Carrie A., Creighton, Chad J., Noebels, Jeffrey L., Scott, Kenneth L., Deneen, Benjamin

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Hyper-SUMOylation of the Kv7 Potassium Channel Diminishes the M-Current Leading to Seizures and Sudden Death von Qi, Yitao, Wang, Jingxiong, Bomben, Valerie C., Li, De-Pei, Chen, Shao-Rui, Sun, Hao, Xi, Yutao, Reed, John G., Cheng, Jinke, Pan, Hui-Lin, Noebels, Jeffrey L., Yeh, Edward T.H.

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Suppression of PKR Promotes Network Excitability and Enhanced Cognition by Interferon-γ-Mediated Disinhibition von Zhu, Ping Jun, Huang, Wei, Kalikulov, Djanenkhodja, Yoo, Jong W., Placzek, Andon N., Stoica, Loredana, Zhou, Hongyi, Bell, John C., Friedlander, Michael J., Krnjević, Krešimir, Noebels, Jeffrey L., Costa-Mattioli, Mauro

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Reduced Cognition in Syngap1 Mutants Is Caused by Isolated Damage within Developing Forebrain Excitatory Neurons von Ozkan, Emin D., Creson, Thomas K., Kramár, Enikö A., Rojas, Camilo, Seese, Ron R., Babyan, Alex H., Shi, Yulin, Lucero, Rocco, Xu, Xiangmin, Noebels, Jeffrey L., Miller, Courtney A., Lynch, Gary, Rumbaugh, Gavin

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Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy von Glasscock, Edward, Yoo, Jong W, Chen, Tim T, Klassen, Tara L, Noebels, Jeffrey L

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Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms von Miao, Qing-Long, Herlitze, Stefan, Mark, Melanie D., Noebels, Jeffrey L.

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Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death von Aiba, Isamu, Wehrens, Xander H. T., Noebels, Jeffrey L.

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Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease von Palop, Jorge J., Chin, Jeannie, Roberson, Erik D., Wang, Jun, Thwin, Myo T., Bien-Ly, Nga, Yoo, Jong, Ho, Kaitlyn O., Yu, Gui-Qiu, Kreitzer, Anatol, Finkbeiner, Steven, Noebels, Jeffrey L., Mucke, Lennart

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Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy von Bomben, Valerie C, Aiba, Isamu, Qian, Jing, Mark, Melanie D, Herlitze, Stefan, Noebels, Jeffrey L

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Arc regulates spine morphology and maintains network stability in vivo von Peebles, Carol L., Yoo, Jong, Thwin, Myo T., Palop, Jorge J., Noebels, Jeffrey L., Finkbeiner, Steven, Snyder, Solomon H.

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Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease von Born, Heather A, Kim, Ji-Yoen, Savjani, Ricky R, Das, Pritam, Dabaghian, Yuri A, Guo, Qinxi, Yoo, Jong W, Schuler, Dorothy R, Cirrito, John R, Zheng, Hui, Golde, Todd E, Noebels, Jeffrey L, Jankowsky, Joanna L

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The biology of epilepsy genes von NOEBELS, Jeffrey L

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Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein von Tang, Maoxue, Gao, Guangping, Rueda, Carlos B., Yu, Hang, Thibodeaux, David N., Awano, Tomoyuki, Engelstad, Kristin M., Sanchez-Quintero, Maria-Jose, Yang, Hong, Li, Fanghua, Li, Huapeng, Su, Qin, Shetler, Kara E., Jones, Lynne, Seo, Ryan, McConathy, Jonathan, Hillman, Elizabeth M., Noebels, Jeffrey L., De Vivo, Darryl C., Monani, Umrao R.

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Visualization of transmitter release with zinc fluorescence detection at the mouse hippocampal mossy fibre synapse von Qian, Jing, Noebels, Jeffrey L.

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A hyperthermic seizure unleashes a surge of spreading depolarizations in Scn1a-deficient mice von Aiba, Isamu, Ning, Yao, Noebels, Jeffrey L

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Identification of new epilepsy treatments: Issues in preclinical methodology von Galanopoulou, Aristea S., Buckmaster, Paul S., Staley, Kevin J., Moshé, Solomon L., Perucca, Emilio, Engel Jr, Jerome, Löscher, Wolfgang, Noebels, Jeffrey L., Pitkänen, Asla, Stables, James, White, H. Steve, O'Brien, Terence J., Simonato for the American Epilepsy Society Basic Science Committee and the International League Against Epilepsy Working Group on Recommendations for Preclinical Epilepsy Drug Discovery, Michele

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Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3 von Seal, Rebecca P., Akil, Omar, Yi, Eunyoung, Weber, Christopher M., Grant, Lisa, Yoo, Jong, Clause, Amanda, Kandler, Karl, Noebels, Jeffrey L., Glowatzki, Elisabeth, Lustig, Lawrence R., Edwards, Robert H.

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Genetic testing in the epilepsies—Report of the ILAE Genetics Commission von Ottman, Ruth, Hirose, Shinichi, Jain, Satish, Lerche, Holger, Lopes‐Cendes, Iscia, Noebels, Jeffrey L., Serratosa, José, Zara, Federico, Scheffer, Ingrid E.

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Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population von Hernandez, Ciria C, Klassen, Tara L, Jackson, Laurel G, Gurba, Katharine, Hu, Ningning, Noebels, Jeffrey L, Macdonald, Robert L

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Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy von Cobos, Inma, Rubenstein, John L R, Calcagnotto, Maria Elisa, Vilaythong, Alex J, Thwin, Myo T, Noebels, Jeffrey L, Baraban, Scott C

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