Epigenetic Regulation of Carbonic Anhydrase 9 Expression by Nitric Oxide in Human Small Airway Epithelial Cells von Moriya, Yuto, Kubota, Sho, Iijima, Yuta, Takasugi, Nobumasa, Uehara, Takashi

Volltext

Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes von Komai, Masato, Noda, Yuka, Ikeda, Atsuya, Kaneshiro, Nanaka, Kamikubo, Yuji, Sakurai, Takashi, Uehara, Takashi, Takasugi, Nobumasa

Volltext

Transcriptome analysis in various cell lines exposed to nitric oxide von Mizushima, Tohta, Kubota, Sho, Iijima, Yuta, Takasugi, Nobumasa, Uehara, Takashi

Volltext

Modulation of Unfolded Protein Response by Methylmercury von Hiraoka, Hideki, Nakahara, Kengo, Kaneko, Yuki, Akiyama, Shiori, Okuda, Kosaku, Iwawaki, Takao, Fujimura, Masatake, Kumagai, Yoshito, Takasugi, Nobumasa, Uehara, Takashi

Volltext

Attenuation of Macrophage Migration Inhibitory Factor-Stimulated Signaling via S-Nitrosylation von Nakahara, Kengo, Fujikawa, Kana, Hiraoka, Hideki, Miyazaki, Ikuko, Asanuma, Masato, Ito, Akihiro, Takasugi, Nobumasa, Uehara, Takashi

Volltext

Spatiotemporal analysis of the UPR transition induced by methylmercury in the mouse brain von Hiraoka, Hideki, Nomura, Ryosuke, Takasugi, Nobumasa, Akai, Ryoko, Iwawaki, Takao, Kumagai, Yoshito, Fujimura, Masatake, Uehara, Takashi

Volltext

FTY720/fingolimod, a sphingosine analogue, reduces amyloid-β production in neurons von Takasugi, Nobumasa, Sasaki, Tomoki, Ebinuma, Ihori, Osawa, Satoko, Isshiki, Hayato, Takeo, Koji, Tomita, Taisuke, Iwatsubo, Takeshi

Volltext

BACE1 activity is modulated by cell-associated sphingosine-1-phosphate von Takasugi, Nobumasa, Sasaki, Tomoki, Suzuki, Kunimichi, Osawa, Satoko, Isshiki, Hayato, Hori, Yukiko, Shimada, Naoaki, Higo, Takuya, Yokoshima, Satoshi, Fukuyama, Tohru, Lee, Virginia M-Y, Trojanowski, John Q, Tomita, Taisuke, Iwatsubo, Takeshi

Volltext

Ex vivo analysis platforms for monitoring amyloid precursor protein cleavage von Kamikubo, Yuji, Jin, Hao, Zhou, Yiyao, Niisato, Kazue, Hashimoto, Yoshie, Takasugi, Nobumasa, Sakurai, Takashi

Volltext

Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis von Okuda, Kosaku, Nakahara, Kengo, Ito, Akihiro, Iijima, Yuta, Nomura, Ryosuke, Kumar, Ashutosh, Fujikawa, Kana, Adachi, Kazuya, Shimada, Yuki, Fujio, Satoshi, Yamamoto, Reina, Takasugi, Nobumasa, Onuma, Kunishige, Osaki, Mitsuhiko, Okada, Futoshi, Ukegawa, Taichi, Takeuchi, Yasuo, Yasui, Norihisa, Yamashita, Atsuko, Marusawa, Hiroyuki, Matsushita, Yosuke, Katagiri, Toyomasa, Shibata, Takahiro, Uchida, Koji, Niu, Sheng-Yong, Lang, Nhi B., Nakamura, Tomohiro, Zhang, Kam Y. J., Lipton, Stuart A., Uehara, Takashi

Volltext

The Pursuit of the "Inside" of the Amyloid Hypothesis-Is C99 a Promising Therapeutic Target for Alzheimer's Disease? von Takasugi, Nobumasa, Komai, Masato, Kaneshiro, Nanaka, Ikeda, Atsuya, Kamikubo, Yuji, Uehara, Takashi

Volltext

The Emerging Role of Electrophiles as a Key Regulator for Endoplasmic Reticulum (ER) Stress von Takasugi, Nobumasa, Hiraoka, Hideki, Nakahara, Kengo, Akiyama, Shiori, Fujikawa, Kana, Nomura, Ryosuke, Furuichi, Moeka, Uehara, Takashi

Volltext

TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes von Takasugi, Nobumasa, Araya, Runa, Kamikubo, Yuji, Kaneshiro, Nanaka, Imaoka, Ryosuke, Jin, Hao, Kashiyama, Taku, Hashimoto, Yoshie, Kurosawa, Masaru, Uehara, Takashi, Nukina, Nobuyuki, Sakurai, Takashi

Volltext

Functional analysis of juxta- and intra-membrane domains of murine APP by genome editing in Neuro2a cells von Kaneshiro, Nanaka, Imaoka, Ryosuke, Komai, Masato, Kashiyama, Taku, Sakurai, Takashi, Uehara, Takashi, Takasugi, Nobumasa

Volltext

Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease von Kaneshiro, Nanaka, Komai, Masato, Imaoka, Ryosuke, Ikeda, Atsuya, Kamikubo, Yuji, Saito, Takashi, Saido, Takaomi C., Tomita, Taisuke, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Sakurai, Takashi, Uehara, Takashi, Takasugi, Nobumasa

Volltext

Potential treatment of Alzheimer's disease astrocyte pathology based on nuclear lipid regulation von Komai, Masato, Takasugi, Nobumasa

Volltext

Molecular Cloning and Characterization of CALP/KChIP4, a Novel EF-hand Protein Interacting with Presenilin 2 and Voltage-gated Potassium Channel Subunit Kv4 von Morohashi, Yuichi, Hatano, Noriyuki, Ohya, Susumu, Takikawa, Rie, Watabiki, Tomonari, Takasugi, Nobumasa, Imaizumi, Yuji, Tomita, Taisuke, Iwatsubo, Takeshi

Volltext

Characterization of pathological changes in the olfactory system of mice exposed to methylmercury von Iijima, Yuta, Miki, Ryohei, Takasugi, Nobumasa, Fujimura, Masatake, Uehara, Takashi

Volltext

Epigenetic Regulation of CXC Chemokine Expression by Environmental Electrophiles Through DNA Methyltransferase Inhibition von Tsuchida, Tomoki, Kubota, Sho, Kamiuezono, Shizuki, Takasugi, Nobumasa, Ito, Akihiro, Kumagai, Yoshito, Uehara, Takashi

Volltext

Therapeutic potential of 4-phenylbutyric acid against methylmercury-induced neuronal cell death in mice von Miki, Ryohei, Nomura, Ryosuke, Iijima, Yuta, Kubota, Sho, Takasugi, Nobumasa, Iwawaki, Takao, Fujimura, Masatake, Uehara, Takashi

Volltext