Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome von De Vita, S, Canzonetta, C, Mulligan, C, Delom, F, Groet, J, Baldo, C, Vanes, L, Dagna-Bricarelli, F, Hoischen, A, Veltman, J, Fisher, E M C, Tybulewicz, V L J, Nizetic, D

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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain von Alić, Ivan, Goh, Pollyanna A., Murray, Aoife, Portelius, Erik, Gkanatsiou, Eleni, Gough, Gillian, Mok, Kin Y., Koschut, David, Brunmeir, Reinhard, Yeap, Yee Jie, O’Brien, Niamh L., Groet, Jürgen, Shao, Xiaowei, Havlicek, Steven, Dunn, N. Ray, Kvartsberg, Hlin, Brinkmalm, Gunnar, Hithersay, Rosalyn, Startin, Carla, Hamburg, Sarah, Phillips, Margaret, Pervushin, Konstantin, Turmaine, Mark, Wallon, David, Rovelet-Lecrux, Anne, Soininen, Hilkka, Volpi, Emanuela, Martin, Joanne E., Foo, Jia Nee, Becker, David L., Rostagno, Agueda, Ghiso, Jorge, Krsnik, Željka, Šimić, Goran, Kostović, Ivica, Mitrečić, Dinko, Francis, Paul T., Blennow, Kaj, Strydom, Andre, Hardy, John, Zetterberg, Henrik, Nižetić, Dean

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Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome von Strydom, Andre, Heslegrave, Amanda, Startin, Carla M, Mok, Kin Y, Hardy, John, Groet, Jurgen, Nizetic, Dean, Zetterberg, Henrik

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Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease von Startin, Carla M, Ashton, Nicholas J, Hamburg, Sarah, Hithersay, Rosalyn, Wiseman, Frances K, Mok, Kin Y, Hardy, John, Lleó, Alberto, Lovestone, Simon, Parnetti, Lucilla, Zetterberg, Henrik, Hye, Abdul, Strydom, André

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Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes von O'Doherty, Aideen, Ruf, Sandra, Mulligan, Claire, Hildreth, Victoria, Errington, Mick L, Cooke, Sam, Sesay, Abdul, Modino, Sonie, Vanes, Lesley, Hernandez, Diana, Linehan, Jacqueline M, Sharpe, Paul T, Brandner, Sebastian, Bliss, Timothy V. P, Henderson, Deborah J, Nizetic, Dean, Tybulewicz, Victor L. J, Fisher, Elizabeth M. C

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Association of dementia with mortality among adults with down syndrome older than 35 years von Hithersay, R, Startin, CM, Hamburg, S, Mok, KY, Hardy, J, Fisher, EMC, Tybulewicz, VLJ, Nizetic, D, Strydom, A

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DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome von Canzonetta, Claudia, Mulligan, Claire, Deutsch, Samuel, Ruf, Sandra, O'Doherty, Aideen, Lyle, Robert, Borel, Christelle, Lin-Marq, Nathalie, Delom, Frederic, Groet, Jürgen, Schnappauf, Felix, De Vita, Serena, Averill, Sharon, Priestley, John V., Martin, Joanne E., Shipley, Janet, Denyer, Gareth, Epstein, Charles J., Fillat, Cristina, Estivill, Xavier, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Antonarakis, Stylianos E., Nizetic, Dean

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Functional genomics of the Down syndrome von Nizetić, D

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A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, FK, Al-Janabi, T, Hardy, J, Karmiloff-Smith, A, Nizetic, D, Tybulewicz, VL, Fisher, EM, Strydom, A

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Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder von Groet, Jürgen, McElwaine, Suzanne, Spinelli, Monica, Rinaldi, Andrea, Burtscher, Ingo, Mulligan, Claire, Mensah, Afua, Cavani, Simona, Dagna-Bricarelli, Franca, Basso, Giuseppe, Cotter, Finbarr E, Nizetic, Dean

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Structural Organization and Regulation of the Small Proline-rich Family of Cornified Envelope Precursors Suggest a Role in Adaptive Barrier Function von Cabral, Adriana, Voskamp, Patrick, Cleton-Jansen, Anne-Marie, South, Andrew, Nizetic, Dean, Backendorf, Claude

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The DNA sequence of human chromosome 21 von Sakaki, Y, Hattori, M, Fujiyama, A, Taylor, T. D, Watanabe, H, Yada, T, Park, H.-S, Toyoda, A, Ishii, K, Totoki, Y, Choi, D.-K, Soeda, E, Ohki, M, Takagi, T, Taudien, S, Blechschmidt, K, Polley, A, Menzel, U, Delabar, J, Kumpf, K, Lehmann, R, Patterson, D, Reichwald, K, Rump, A, Schillhabel, M, Schudy, A, Zimmermann, W, Rosenthal, A, Kudoh, J, Shibuya, K, Kawasaki, K, Asakawa, S, Shintani, A, Sasaki, T, Nagamine, K, Mitsuyama, S, Antonarakis, S. E, Minoshima, S, Shimizu, N, Nordsiek, G, Hornischer, K, Brandt, P, Scharfe, M, Schön, O, Desario, A, Reichelt, J, Kauer, G, Blöcker, H, Ramser, J, Beck, A, Klages, S, Hennig, S, Riesselmann, L, Dagand, E, Haaf, T, Wehrmeyer, S, Borzym, K, Gardiner, K, Nizetic, D, Francis, F, Lehrach, H, Reinhardt, R, Yaspo, M.-L

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Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex von Huber, Marcel, Siegenthaler, Georges, Mirancea, Nicolae, Marenholz, Ingo, Nizetic, Dean, Breitkreutz, Dirk, Mischke, Dietmar, Hohl, Daniel

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An improved bacterial colony lysis procedure enables direct DNA hybridisation using short (10, 11 bases) oligonucleotides to cosmids von NIZETIC, D, DRMANAC, R, LEHRACH, H

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Fusion of two novel genes, RBM15 and MKL1 , in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia von Morris, Stephan W, Hitzler, Johann K, Ma, Zhigui, Valentine, Virginia, L, Martin, Herbrick, Jo-Anne, Cui, Xiaoli, Bouman, Derek, Li, Yue, Mehta, Perdeep K, Nizetic, Dean, Kaneko, Yasuhiko, Chan, Godfrey C.F, Chan, Li C, Squire, Jeremy, Scherer, Stephen W

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Construction, Arraying, and High-Density Screening of Large Insert Libraries of Human Chromosomes X and 21: Their Potential Use as Reference Libraries von Nizetic, Dean, Zehetner, Gunther, Monaco, Anthony P., Gellen, Lisa, Young, Bryan D., Lehrach, Hans

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Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle von SCARTEZZINI, P, EGEO, A, COLELLA, S, FUMAGALLI, P, ARRIGO, P, NIZETIC, D, TARAMELLI, R, RASORE-QUARTINO, A

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Construction of cosmid libraries from flow-sorted human chromosomes 1, 6, 7, 11, 13, and 18 for reference library resources von Nizetic, D, Monard, S, Young, B, Cotter, F, Zehetner, G, Lehrach, H

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The homeobox gene MEIS1 is amplified in IMR-32 and highly expressed in other neuroblastoma cell lines von Jones, T.A., Flomen, R.H., Senger, G., Nižetić, D., Sheer, D.

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An integrated YAC-overlap and ‘cosmid-pocket’ map of the human chromosome 21 von Nižetić, Dean, Gellen, Lisa, Hamvas, Renata M. J., Mott, Richard, Grigorlev, Andrei, Vatcheva, Radost, Zehetner, Günther, Yaspo, Marie-Laure, Dutriaux, Annie, Lopes, Carmela, Delabar, Jean-M., Van Broeckhoven, Christine, Potler, Marie-Claude, Lehrach, Hans

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