Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome von De Vita, S, Canzonetta, C, Mulligan, C, Delom, F, Groet, J, Baldo, C, Vanes, L, Dagna-Bricarelli, F, Hoischen, A, Veltman, J, Fisher, E M C, Tybulewicz, V L J, Nizetic, D

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Functional genomics of the Down syndrome von Nizetić, D

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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain von Alić, Ivan, Goh, Pollyanna A., Murray, Aoife, Portelius, Erik, Gkanatsiou, Eleni, Gough, Gillian, Mok, Kin Y., Koschut, David, Brunmeir, Reinhard, Yeap, Yee Jie, O’Brien, Niamh L., Groet, Jürgen, Shao, Xiaowei, Havlicek, Steven, Dunn, N. Ray, Kvartsberg, Hlin, Brinkmalm, Gunnar, Hithersay, Rosalyn, Startin, Carla, Hamburg, Sarah, Phillips, Margaret, Pervushin, Konstantin, Turmaine, Mark, Wallon, David, Rovelet-Lecrux, Anne, Soininen, Hilkka, Volpi, Emanuela, Martin, Joanne E., Foo, Jia Nee, Becker, David L., Rostagno, Agueda, Ghiso, Jorge, Krsnik, Željka, Šimić, Goran, Kostović, Ivica, Mitrečić, Dinko, Francis, Paul T., Blennow, Kaj, Strydom, Andre, Hardy, John, Zetterberg, Henrik, Nižetić, Dean

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A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, FK, Al-Janabi, T, Hardy, J, Karmiloff-Smith, A, Nizetic, D, Tybulewicz, VL, Fisher, EM, Strydom, A

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Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome von Strydom, Andre, Heslegrave, Amanda, Startin, Carla M, Mok, Kin Y, Hardy, John, Groet, Jurgen, Nizetic, Dean, Zetterberg, Henrik

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Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease von Startin, Carla M, Ashton, Nicholas J, Hamburg, Sarah, Hithersay, Rosalyn, Wiseman, Frances K, Mok, Kin Y, Hardy, John, Lleó, Alberto, Lovestone, Simon, Parnetti, Lucilla, Zetterberg, Henrik, Hye, Abdul, Strydom, André

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The importance of understanding individual differences in Down syndrome von Karmiloff-Smith, A, Al-Janabi, T, D'Souza, H, Groet, J, Massand, E, Mok, K, Startin, C, Fisher, E, Hardy, J, Nizetic, D, Tybulewicz, V, Strydom, A

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Association of dementia with mortality among adults with down syndrome older than 35 years von Hithersay, R, Startin, CM, Hamburg, S, Mok, KY, Hardy, J, Fisher, EMC, Tybulewicz, VLJ, Nizetic, D, Strydom, A

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Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes von O'Doherty, Aideen, Ruf, Sandra, Mulligan, Claire, Hildreth, Victoria, Errington, Mick L, Cooke, Sam, Sesay, Abdul, Modino, Sonie, Vanes, Lesley, Hernandez, Diana, Linehan, Jacqueline M, Sharpe, Paul T, Brandner, Sebastian, Bliss, Timothy V. P, Henderson, Deborah J, Nizetic, Dean, Tybulewicz, Victor L. J, Fisher, Elizabeth M. C

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DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome von Canzonetta, Claudia, Mulligan, Claire, Deutsch, Samuel, Ruf, Sandra, O'Doherty, Aideen, Lyle, Robert, Borel, Christelle, Lin-Marq, Nathalie, Delom, Frederic, Groet, Jürgen, Schnappauf, Felix, De Vita, Serena, Averill, Sharon, Priestley, John V., Martin, Joanne E., Shipley, Janet, Denyer, Gareth, Epstein, Charles J., Fillat, Cristina, Estivill, Xavier, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Antonarakis, Stylianos E., Nizetic, Dean

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High-Resolution YAC Fragmentation Map of 1q21 von Lioumi, Maria, Olavesen, M.G., Nizetic, Dean, Ragoussis, Jiannis

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An improved bacterial colony lysis procedure enables direct DNA hybridisation using short (10, 11 bases) oligonucleotides to cosmids von NIZETIC, D, DRMANAC, R, LEHRACH, H

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Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder von Groet, Jürgen, McElwaine, Suzanne, Spinelli, Monica, Rinaldi, Andrea, Burtscher, Ingo, Mulligan, Claire, Mensah, Afua, Cavani, Simona, Dagna-Bricarelli, Franca, Basso, Giuseppe, Cotter, Finbarr E, Nizetic, Dean

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The DNA sequence of human chromosome 21 von Sakaki, Y, Hattori, M, Fujiyama, A, Taylor, T. D, Watanabe, H, Yada, T, Park, H.-S, Toyoda, A, Ishii, K, Totoki, Y, Choi, D.-K, Soeda, E, Ohki, M, Takagi, T, Taudien, S, Blechschmidt, K, Polley, A, Menzel, U, Delabar, J, Kumpf, K, Lehmann, R, Patterson, D, Reichwald, K, Rump, A, Schillhabel, M, Schudy, A, Zimmermann, W, Rosenthal, A, Kudoh, J, Shibuya, K, Kawasaki, K, Asakawa, S, Shintani, A, Sasaki, T, Nagamine, K, Mitsuyama, S, Antonarakis, S. E, Minoshima, S, Shimizu, N, Nordsiek, G, Hornischer, K, Brandt, P, Scharfe, M, Schön, O, Desario, A, Reichelt, J, Kauer, G, Blöcker, H, Ramser, J, Beck, A, Klages, S, Hennig, S, Riesselmann, L, Dagand, E, Haaf, T, Wehrmeyer, S, Borzym, K, Gardiner, K, Nizetic, D, Francis, F, Lehrach, H, Reinhardt, R, Yaspo, M.-L

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Structural Organization and Regulation of the Small Proline-rich Family of Cornified Envelope Precursors Suggest a Role in Adaptive Barrier Function von Cabral, Adriana, Voskamp, Patrick, Cleton-Jansen, Anne-Marie, South, Andrew, Nizetic, Dean, Backendorf, Claude

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Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex von Huber, Marcel, Siegenthaler, Georges, Mirancea, Nicolae, Marenholz, Ingo, Nizetic, Dean, Breitkreutz, Dirk, Mischke, Dietmar, Hohl, Daniel

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Fusion of two novel genes, RBM15 and MKL1 , in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia von Morris, Stephan W, Hitzler, Johann K, Ma, Zhigui, Valentine, Virginia, L, Martin, Herbrick, Jo-Anne, Cui, Xiaoli, Bouman, Derek, Li, Yue, Mehta, Perdeep K, Nizetic, Dean, Kaneko, Yasuhiko, Chan, Godfrey C.F, Chan, Li C, Squire, Jeremy, Scherer, Stephen W

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Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle von SCARTEZZINI, P, EGEO, A, COLELLA, S, FUMAGALLI, P, ARRIGO, P, NIZETIC, D, TARAMELLI, R, RASORE-QUARTINO, A

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Construction of cosmid libraries from flow-sorted human chromosomes 1, 6, 7, 11, 13, and 18 for reference library resources von Nizetic, D, Monard, S, Young, B, Cotter, F, Zehetner, G, Lehrach, H

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An integrated YAC-overlap and ‘cosmid-pocket’ map of the human chromosome 21 von Nižetić, Dean, Gellen, Lisa, Hamvas, Renata M. J., Mott, Richard, Grigorlev, Andrei, Vatcheva, Radost, Zehetner, Günther, Yaspo, Marie-Laure, Dutriaux, Annie, Lopes, Carmela, Delabar, Jean-M., Van Broeckhoven, Christine, Potler, Marie-Claude, Lehrach, Hans

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