Construction, Arraying, and High-Density Screening of Large Insert Libraries of Human Chromosomes X and 21: Their Potential Use as Reference Libraries von Nizetic, Dean, Zehetner, Gunther, Monaco, Anthony P., Gellen, Lisa, Young, Bryan D., Lehrach, Hans

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Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome von De Vita, S, Canzonetta, C, Mulligan, C, Delom, F, Groet, J, Baldo, C, Vanes, L, Dagna-Bricarelli, F, Hoischen, A, Veltman, J, Fisher, E M C, Tybulewicz, V L J, Nizetic, D

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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain von Alić, Ivan, Goh, Pollyanna A., Murray, Aoife, Portelius, Erik, Gkanatsiou, Eleni, Gough, Gillian, Mok, Kin Y., Koschut, David, Brunmeir, Reinhard, Yeap, Yee Jie, O’Brien, Niamh L., Groet, Jürgen, Shao, Xiaowei, Havlicek, Steven, Dunn, N. Ray, Kvartsberg, Hlin, Brinkmalm, Gunnar, Hithersay, Rosalyn, Startin, Carla, Hamburg, Sarah, Phillips, Margaret, Pervushin, Konstantin, Turmaine, Mark, Wallon, David, Rovelet-Lecrux, Anne, Soininen, Hilkka, Volpi, Emanuela, Martin, Joanne E., Foo, Jia Nee, Becker, David L., Rostagno, Agueda, Ghiso, Jorge, Krsnik, Željka, Šimić, Goran, Kostović, Ivica, Mitrečić, Dinko, Francis, Paul T., Blennow, Kaj, Strydom, Andre, Hardy, John, Zetterberg, Henrik, Nižetić, Dean

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The homeobox gene MEIS1 is amplified in IMR-32 and highly expressed in other neuroblastoma cell lines von Jones, T.A., Flomen, R.H., Senger, G., Nižetić, D., Sheer, D.

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Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome von Groet, J, Ives, J H, South, A P, Baptista, P R, Jones, T A, Yaspo, M L, Lehrach, H, Potier, M C, Van Broeckhoven, C, Nizetić, D

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Cytogenetic and molecular study of 32 Down syndrome families: potential leukaemia predisposing role of the most proximal segment of chromosome 21q von Cavani, Simona, Perfumo, Chiara, Argusti, Alessandra, Pierluigi, Mauro, Perroni, Lucia, Schmiegelow, Kjeld, Petersen, Michael B., Cotter, Finbarr E., Strigini, Paolo, Dagna‐Bricarelli, Franca, NižetiĆ, Dean

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Rieger syndrome locus: a new reciprocal translocation t(4;12)(q25;q15) and a deletion del(4)(q25q27) both break between markers D4S2945 and D4S193 von Flomen, R H, Gorman, P A, Vatcheva, R, Groet, J, Barisić, I, Ligutić, I, Sheer, D, Nizetić, D

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Major Histocompatibility Complex Gene Organization in the Mole Rat Spalax ehrenbergi: Evidence for Transfer of Function between Class II Genes von Nizetić, Dean, Figueroa, Felipe, Dembić, Zlatko, Nevo, Eviatar, Klein, Jan

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Increased levels of a chromosome 21-encoded tumour invasion and metastasis factor (TIAM1) mRNA in bone marrow of down syndrome children during the acute phase of AML(M7) von Ives, Jane H., Dagna-Bricarelli, Franca, Basso, Giuseppe, Antonarakis, Stylianos E., Jee, Roger, Cotter, Finbarr, Nižetić, Dean

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Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome von Strydom, Andre, Heslegrave, Amanda, Startin, Carla M, Mok, Kin Y, Hardy, John, Groet, Jurgen, Nizetic, Dean, Zetterberg, Henrik

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Functional genomics of the Down syndrome von Nizetić, D

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Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease von Startin, Carla M, Ashton, Nicholas J, Hamburg, Sarah, Hithersay, Rosalyn, Wiseman, Frances K, Mok, Kin Y, Hardy, John, Lleó, Alberto, Lovestone, Simon, Parnetti, Lucilla, Zetterberg, Henrik, Hye, Abdul, Strydom, André

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Evolution of Mouse Major Histocompatibility Complex Genes Borne by t Chromosomes von Figueroa, Felipe, Golubic, Mladen, Nizetic, Dean, Klein, Jan

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Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes von O'Doherty, Aideen, Ruf, Sandra, Mulligan, Claire, Hildreth, Victoria, Errington, Mick L, Cooke, Sam, Sesay, Abdul, Modino, Sonie, Vanes, Lesley, Hernandez, Diana, Linehan, Jacqueline M, Sharpe, Paul T, Brandner, Sebastian, Bliss, Timothy V. P, Henderson, Deborah J, Nizetic, Dean, Tybulewicz, Victor L. J, Fisher, Elizabeth M. C

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Association of dementia with mortality among adults with down syndrome older than 35 years von Hithersay, R, Startin, CM, Hamburg, S, Mok, KY, Hardy, J, Fisher, EMC, Tybulewicz, VLJ, Nizetic, D, Strydom, A

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DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome von Canzonetta, Claudia, Mulligan, Claire, Deutsch, Samuel, Ruf, Sandra, O'Doherty, Aideen, Lyle, Robert, Borel, Christelle, Lin-Marq, Nathalie, Delom, Frederic, Groet, Jürgen, Schnappauf, Felix, De Vita, Serena, Averill, Sharon, Priestley, John V., Martin, Joanne E., Shipley, Janet, Denyer, Gareth, Epstein, Charles J., Fillat, Cristina, Estivill, Xavier, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Antonarakis, Stylianos E., Nizetic, Dean

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Evolutionary diversification of class II P loci in the Mhc of the mole-rat Spalax ehrenbergi von SCHÖPFER, R, FIGUEROA, F, NIZETIC, D, NEVO, E, KLEIN, J

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An integrated YAC-overlap and ‘cosmid-pocket’ map of the human chromosome 21 von Nižetić, Dean, Gellen, Lisa, Hamvas, Renata M. J., Mott, Richard, Grigorlev, Andrei, Vatcheva, Radost, Zehetner, Günther, Yaspo, Marie-Laure, Dutriaux, Annie, Lopes, Carmela, Delabar, Jean-M., Van Broeckhoven, Christine, Potler, Marie-Claude, Lehrach, Hans

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Evolutionary expansion of Mhc class I loci in the mole-rat, Spalax ehrenbergi von VINCEK, V, NIZETIC, D, GOLUBIC, M, FIGUEROA, F, NEVO, E, KLEIN, J

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A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, FK, Al-Janabi, T, Hardy, J, Karmiloff-Smith, A, Nizetic, D, Tybulewicz, VL, Fisher, EM, Strydom, A

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