Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species von Foti, Robert S., Biswas, Kaustav, Aral, Jennifer, Be, Xuhai, Berry, Loren, Cheng, Yuan, Conner, Kip, Falsey, James R., Glaus, Charles, Herberich, Brad, Hickman, Dean, Ikotun, Tayo, Li, Hongyan, Long, Jason, Huang, Liyue, Miranda, Les P., Murray, Justin, Moyer, Bryan, Netirojjanakul, Chawita, Nixey, Thomas E., Sham, Kelvin, Soto, Marcus, Tegley, Christopher M., Tran, Linh, Wu, Bin, Yin, Lin, Rock, Dan A.

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Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx‑1 Peptide–Antibody Conjugates von Biswas, Kaustav, Nixey, Thomas E, Murray, Justin K, Falsey, James R, Yin, Li, Liu, Hantao, Gingras, Jacinthe, Hall, Brian E, Herberich, Brad, Holder, Jerry Ryan, Li, Hongyan, Ligutti, Joseph, Lin, Min-Hwa Jasmine, Liu, Dong, Soriano, Brian D, Soto, Marcus, Tran, Linh, Tegley, Christopher M, Zou, Anrou, Gunasekaran, Kannan, Moyer, Bryan D, Doherty, Liz, Miranda, Les P

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Engineering Na V 1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics von Murray, Justin K, Wu, Bin, Tegley, Christopher M, Nixey, Thomas E, Falsey, James R, Herberich, Brad, Yin, Li, Sham, Kelvin, Long, Jason, Aral, Jennifer, Cheng, Yuan, Netirojjanakul, Chawita, Doherty, Liz, Glaus, Charles, Ikotun, Tayo, Li, Hongyan, Tran, Linh, Soto, Marcus, Salimi-Moosavi, Hossein, Ligutti, Joseph, Amagasu, Shanti, Andrews, Kristin L, Be, Xuhai, Lin, Min-Hwa Jasmine, Foti, Robert S, Ilch, Christopher P, Youngblood, Beth, Kornecook, Thomas J, Karow, Margaret, Walker, Kenneth W, Moyer, Bryan D, Biswas, Kaustav, Miranda, Les P

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Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates von Biswas, Kaustav, Nixey, Thomas E, Murray, Justin K, Falsey, James R, Yin, Li, Liu, Hantao, Gingras, Jacinthe, Hall, Brian E, Herberich, Brad, Holder, Jerry Ryan, Li, Hongyan, Ligutti, Joseph, Lin, Min-Hwa Jasmine, Liu, Dong, Soriano, Brian D, Soto, Marcus, Tran, Linh, Tegley, Christopher M, Zou, Anrou, Gunasekaran, Kannan, Moyer, Bryan D, Doherty, Liz, Miranda, Les P

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Engineering NaV1.7 Inhibitory JzTx‑V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics von Murray, Justin K, Wu, Bin, Tegley, Christopher M, Nixey, Thomas E, Falsey, James R, Herberich, Brad, Yin, Li, Sham, Kelvin, Long, Jason, Aral, Jennifer, Cheng, Yuan, Netirojjanakul, Chawita, Doherty, Liz, Glaus, Charles, Ikotun, Tayo, Li, Hongyan, Tran, Linh, Soto, Marcus, Salimi-Moosavi, Hossein, Ligutti, Joseph, Amagasu, Shanti, Andrews, Kristin L, Be, Xuhai, Lin, Min-Hwa Jasmine, Foti, Robert S, Ilch, Christopher P, Youngblood, Beth, Kornecook, Thomas J, Karow, Margaret, Walker, Kenneth W, Moyer, Bryan D, Biswas, Kaustav, Miranda, Les P

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Intramolecular Diels-Alder reactions of 2H-thiopyran dienes von Ward, Dale E, Nixey, Thomas E, Gai, Yuanzhu, Hrapchak, Matthew J, Abaee, M. Saeed

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Intramolecular Diels-Alder reactions of 2 H-thiopyrans von Ward, Dale E., Nixey, Thomas E.

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Intramolecular Diels-Alder reactions of 2H-thiopyrans von WARD, D. E, NIXEY, T. E

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Intramolecular Diels–Alder reactions of 2 H -thiopyran dienes von Ward, Dale E., Nixey, Thomas E., Gai, Yuanzhu, Hrapchak, Matthew J., Abaee, M. Saeed

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From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) von Cheng, Yuan, Judd, Ted C, Bartberger, Michael D, Brown, James, Chen, Kui, Fremeau, Robert T, Hickman, Dean, Hitchcock, Stephen A, Jordan, Brad, Li, Vivian, Lopez, Patricia, Louie, Steven W, Luo, Yi, Michelsen, Klaus, Nixey, Thomas, Powers, Timothy S, Rattan, Claire, Sickmier, E. Allen, St. Jean, David J, Wahl, Robert C, Wen, Paul H, Wood, Stephen

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Novel Vanilloid Receptor-1 Antagonists:  2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate von Doherty, Elizabeth M, Fotsch, Christopher, Bannon, Anthony W, Bo, Yunxin, Chen, Ning, Dominguez, Celia, Falsey, James, Gavva, Narender R, Katon, Jodie, Nixey, Thomas, Ognyanov, Vassil I, Pettus, Liping, Rzasa, Robert M, Stec, Markian, Surapaneni, Sekhar, Tamir, Rami, Zhu, Jiawang, Treanor, James J. S, Norman, Mark H

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Novel Vanilloid Receptor-1 Antagonists:  1. Conformationally Restricted Analogues of trans-Cinnamides von Norman, Mark H, Zhu, Jiawang, Fotsch, Christopher, Bo, Yunxin, Chen, Ning, Chakrabarti, Partha, Doherty, Elizabeth M, Gavva, Narender R, Nishimura, Nobuko, Nixey, Thomas, Ognyanov, Vassil I, Rzasa, Robert M, Stec, Markian, Surapaneni, Sekhar, Tamir, Rami, Viswanadhan, Vellarkad N, Treanor, James J. S

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One-pot microwave assisted preparation of pyrazoloquinazolinone libraries von Vasquez, Jr, Thomas E, Nixey, Thomas, Chenera, Balan, Gore, Vijay, Bartberger, Michael D, Sun, Yaxiong, Hulme, Christopher

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Agonistas del receptor APJ y usos de los mismos von ARAL, Jennifer, DOHERTY, Elizabeth M, MIRANDA, Leslie P, SWAMINATH, Gayathri, NIXEY, Thomas, HOLDER, Jerry Ryan

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BETA-SECRETASE MODULATORS AND METHODS OF USE von PATEL, VINOD F, GRACEFFA, RUSSELL, NIXEY, THOMAS, HARRIED, SCOTT, NGUYEN, THOMAS, BROWN, RYAN, PENNINGTON, LEWIS, LA, DANIEL, CHENG, YUAN, CROGHAN, MICHAEL, KREIMAN, CHARLES, BROWN, JAMES, JUDD, TED, WEISS, MATTHEW, BARTBERGER, MICHAEL, HITCHCOCK, STEPHEN, ZHONG, WENGE, ALBRECHT, BRIAN K, LOPEZ, PATRICIA, KALLER, MATTHEW, ANDERSEN, DENISE LYN, HUNGATE, RANDALL, MASSE, CRAIG E, YANG, BRYANT, MONENSCHEIN, HOLGER, XUE, QIUFEN, CHAFFEE, STUART C

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VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS von THOMAS NIXEY

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PIPERIDINYL- AND PIPERAZINYL-SUBSTITUTED HETEROAROMATIC CARBOXAMIDES AS MODULATORS OF GPR6 von Thomas NIXEY, Andre A. KIRYANOV, Jason GREEN, Maria HOPKINS, Holger MONENSCHEIN, Sean MURPHY, Huikai SUN, Jon KUEHLER, Benjamin JONES

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Nitrogen-containing bicyclic hetroaryl compounds for the treatment of RAF protein kinase-mediated diseases von SMITH, ADRIAN L, DOHERTY, ELIZABETH M, PARAS, NICK A, NIXEY, THOMAS, RETZ, DANIEL M, KIM, JOSEPH L, CHEN, JIAN J, LIU, GANG, TASKER, ANDREW, DE MORIN, FRENEL F, HUANG, QI, ZHU, JIAWANG, PETKUS, JEFFREY, HITCHCOCK, STEPHEN

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NITROGEN-CONTAINING BICYCLIC HETEROARYL COMPOUNDS AND METHODS OF USE von DOHERTY, ELIZABETH M, PARAS, NICK A, NIXEY, THOMAS, SMITH, ADRIAN LEONARD, KIM, JOSEPH L, RETZ, DANIEL MARTIN, CHEN, JIAN J, LIU, GANG, TASKER, ANDREW, DE MORIN, FRENEL F, HUANG, QI, ZHU, JIAWANG, PETKUS, JEFFREY, HITCHCOCK, STEPHEN

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Substituted pyrimidine compounds as RAF inhibitors and methods of use von LIU GANG, HITCHCOCK STEPHEN A, DOHERTY ELIZABETH M, ZHU JIAWANG, HUANG QI, PETKUS JEFFREY, PARAS NICK A, DE MORIN FRENEL F, CHEN JIAN J, RETZ DANIEL MARTIN, SMITH ADRIAN LEONARD, KIM JOSEPH L, NIXEY THOMAS

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