Pathogenesis of Lafora Disease: Transition of Soluble Glycogen to Insoluble Polyglucosan von Sullivan, Mitchell A, Nitschke, Silvia, Steup, Martin, Minassian, Berge A, Nitschke, Felix

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Ppp1r3d deficiency preferentially inhibits neuronal and cardiac Lafora body formation in a mouse model of the fatal epilepsy Lafora disease von Israelian, Lori, Nitschke, Silvia, Wang, Peixiang, Zhao, Xiaochu, Perri, Ami M., Lee, Jennifer P.Y., Verhalen, Brandy, Nitschke, Felix, Minassian, Berge A.

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Glycogen synthase downregulation rescues the amylopectinosis of murine RBCK1 deficiency von Nitschke, Silvia, Sullivan, Mitchell A, Mitra, Sharmistha, Marchioni, Charlotte R, Lee, Jennifer P Y, Smith, Brandon H, Ahonen, Saija, Wu, Jun, Chown, Erin E, Wang, Peixiang, Petković, Sara, Zhao, Xiaochu, DiGiovanni, Laura F, Perri, Ami M, Israelian, Lori, Grossman, Tamar R, Kordasiewicz, Holly, Vilaplana, Francisco, Iwai, Kazuhiro, Nitschke, Felix, Minassian, Berge A

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Skeletal Muscle Glycogen Chain Length Correlates with Insolubility in Mouse Models of Polyglucosan-Associated Neurodegenerative Diseases von Sullivan, Mitchell A., Nitschke, Silvia, Skwara, Evan P., Wang, Peixiang, Zhao, Xiaochu, Pan, Xiao S., Chown, Erin E., Wang, Travis, Perri, Ami M., Lee, Jennifer P.Y., Vilaplana, Francisco, Minassian, Berge A., Nitschke, Felix

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Transition from glycogen to starch metabolism in Archaeplastida von Cenci, Ugo, Nitschke, Felix, Steup, Martin, Minassian, Berge A., Colleoni, Christophe, Ball, Steven G.

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Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease von Nitschke, Felix, Sullivan, Mitchell A, Wang, Peixiang, Zhao, Xiaochu, Chown, Erin E, Perri, Ami M, Israelian, Lori, Juana‐López, Lucia, Bovolenta, Paola, Rodríguez de Córdoba, Santiago, Steup, Martin, Minassian, Berge A

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GDE5/Gpcpd1 activity determines phosphatidylcholine composition in skeletal muscle and regulates contractile force in mice von Aisyah, Rahmawati, Ohshima, Noriyasu, Watanabe, Daiki, Nakagawa, Yoshiko, Sakuma, Tetsushi, Nitschke, Felix, Nakamura, Minako, Sato, Koji, Nakahata, Kaori, Yokoyama, Chihiro, Marchioni, Charlotte R., Kumrungsee, Thanutchaporn, Shimizu, Takahiko, Sotomaru, Yusuke, Takeo, Toru, Nakagata, Naomi, Izumi, Takashi, Miura, Shinji, Minassian, Berge A., Yamamoto, Takashi, Wada, Masanobu, Yanaka, Noriyuki

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Lafora disease — from pathogenesis to treatment strategies von Nitschke, Felix, Ahonen, Saija J., Nitschke, Silvia, Mitra, Sharmistha, Minassian, Berge A.

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Determination of glucan phosphorylation using heteronuclear 1H,13C double and 1H,13C,31P triple-resonance NMR spectra von Schmieder, Peter, Nitschke, Felix, Steup, Martin, Mallow, Keven, Specker, Edgar

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Novel Cross-Correction–Enabled Gene Therapy for CDKL5-Deficiency Disorder von Nitschke, Felix, Montalbano, Alina P.

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Gys1 antisense therapy rescues neuropathological bases of murine Lafora disease von Ahonen, Saija, Nitschke, Silvia, Grossman, Tamar R, Kordasiewicz, Holly, Wang, Peixiang, Zhao, Xiaochu, Guisso, Dikran R, Kasiri, Sahba, Nitschke, Felix, Minassian, Berge A

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Sensitive quantification of α-glucans in mouse tissues, cell cultures, and human cerebrospinal fluid von Nitschke, Silvia, Petković, Sara, Ahonen, Saija, Minassian, Berge A., Nitschke, Felix

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CRISPR-Cas9-mediated editing of starch branching enzymes results in altered starch structure in Brassica napus von Wang, Liping, Wang, You, Makhmoudova, Amina, Nitschke, Felix, Tetlow, Ian J, Emes, Michael J

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Targeting Gys1 with AAV‐SaCas9 Decreases Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models von Gumusgoz, Emrah, Guisso, Dikran R, Kasiri, Sahba, Wu, Jun, Dear, Matthew, Verhalen, Brandy, Nitschke, Silvia, Mitra, Sharmistha, Nitschke, Felix, Minassian, Berge A.

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Myofiber-type-dependent ‘boulder’ or ‘multitudinous pebble’ formations across distinct amylopectinoses von Mitra, Sharmistha, Chen, Baozhi, Shelton, John M., Nitschke, Silvia, Wu, Jun, Covington, Lindsay, Dear, Mathew, Lynn, Tori, Verma, Mayank, Nitschke, Felix, Fuseya, Yasuhiro, Iwai, Kazuhiro, Evers, Bret M., Minassian, Berge A.

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Stress impairs response to antidepressants via HPA axis and immune system activation von Menke, Andreas, Nitschke, Felix, Hellmuth, Anna, Helmel, Jacqueline, Wurst, Catherina, Stonawski, Saskia, Blickle, Manuel, Weiß, Carolin, Weber, Heike, Hommers, Leif, Domschke, Katharina, Deckert, Jürgen

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An inducible glycogen synthase-1 knockout halts but does not reverse Lafora disease progression in mice von Nitschke, Silvia, Chown, Erin E., Zhao, Xiaochu, Gabrielian, Shoghig, Petković, Sara, Guisso, Dikran R., Perri, Ami M., Wang, Peixiang, Ahonen, Saija, Nitschke, Felix, Minassian, Berge A.

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Extent of cortisol suppression at baseline predicts improvement in HPA axis function during antidepressant treatment von Scherf-Clavel, Maike, Wurst, Catherina, Nitschke, Felix, Stonawski, Saskia, Burschka, Carolin, Friess, Lisa, Unterecker, Stefan, Hommers, Leif, Deckert, Jürgen, Domschke, Katharina, Menke, Andreas

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Impaired fear learning and extinction, but not generalization, in anxious and non-anxious depression von Wurst, Catherina, Schiele, Miriam A., Stonawski, Saskia, Weiß, Carolin, Nitschke, Felix, Hommers, Leif, Domschke, Katharina, Herrmann, Martin J., Pauli, Paul, Deckert, Jürgen, Menke, Andreas

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S39FKBP5 AND SGK1 SIGNALING PREDICT RESPONSE IN MAJOR DEPRESSION von Menke, Andreas, Fietz, Jasmin, Helmuth, Anna, Nitschke, Felix, Wurst, Catherina, Weber, Heike, Domschke, Katharina, Deckert, Jürgen

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