Targeting DNA topoisomerase II in cancer chemotherapy von Nitiss, John L

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DNA topoisomerase II and its growing repertoire of biological functions von Nitiss, John L

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Roles of eukaryotic topoisomerases in transcription, replication and genomic stability von Pommier, Yves, Sun, Yilun, Huang, Shar-yin N., Nitiss, John L.

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Using energy to go downhill—a genoprotective role for ATPase activity in DNA topoisomerase II von Bandak, Afif F, Blower, Tim R, Nitiss, Karin C, Shah, Viraj, Nitiss, John L, Berger, James M

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Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes von Katyal, Sachin, Lee, Youngsoo, Nitiss, Karin C, Downing, Susanna M, Li, Yang, Shimada, Mikio, Zhao, Jingfeng, Russell, Helen R, Petrini, John H J, Nitiss, John L, McKinnon, Peter J

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Genome Instability Induced by Topoisomerase Misfunction von Nitiss, Karin C, Bandak, Afif, Berger, James M, Nitiss, John L

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Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2) von Gao, Rui, Schellenberg, Matthew J., Huang, Shar-yin N., Abdelmalak, Monica, Marchand, Christophe, Nitiss, Karin C., Nitiss, John L., Williams, R. Scott, Pommier, Yves

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Modeling allosteric mechanisms of eukaryotic type II topoisomerases von Evoli, Stefania, Kariyawasam, Nilusha L., Nitiss, Karin C., Nitiss, John L., Wereszczynski, Jeff

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Twisting and ironing: doxorubicin cardiotoxicity by mitochondrial DNA damage von Nitiss, Karin C, Nitiss, John L

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Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers von Boot, Arnoud, Liu, Mo, Stantial, Nicole, Shah, Viraj, Yu, Willie, Nitiss, Karin C., Nitiss, John L., Jinks-Robertson, Sue, Rozen, Steven G.

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TDP1 is required for efficient non-homologous end joining in human cells von Li, Jing, Summerlin, Matthew, Nitiss, Karin C., Nitiss, John L., Hanakahi, Leslyn A.

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Tdp2: a means to fixing the ends von Nitiss, John L, Nitiss, Karin C

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A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation von Sun, Yilun, Miller Jenkins, Lisa M, Su, Yijun P, Nitiss, Karin C, Nitiss, John L, Pommier, Yves

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Naturally mutagenic sequence diversity in a human type II topoisomerase von Bandak, Afif F, Blower, Tim R, Nitiss, Karin C, Gupta, Raveena, Lau, Albert Y, Guha, Ria, Nitiss, John L, Berger, James M

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Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast von Stantial, Nicole, Rogojina, Anna, Gilbertson, Matthew, Sun, Yilun, Miles, Hannah, Shaltz, Samantha, Berger, James, Nitiss, Karin C., Jinks-Robertson, Sue, Nitiss, John L.

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Detection of Topoisomerase Covalent Complexes in Eukaryotic Cells von Anand, Jay, Sun, Yilun, Zhao, Yang, Nitiss, Karin C., Nitiss, John L.

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DNA Damage by an essential enzyme: A delicate balance act on the tightrope von Nitiss, Karin C., Nitiss, John L., Hanakahi, Leslyn A.

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Editorial: The repair of DNA-protein crosslinks von Sun, Yilun, Nitiss, John L, Pommier, Yves

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Requirements for MRN endonuclease processing of topoisomerase II-mediated DNA damage in mammalian cells von Sun, Yilun, Soans, Eroica, Mishina, Margarita, Petricci, Elena, Pommier, Yves, Nitiss, Karin C., Nitiss, John L.

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TDP1 promotes assembly of non-homologous end joining protein complexes on DNA von Heo, Jinho, Li, Jing, Summerlin, Matthew, Hays, Annette, Katyal, Sachin, McKinnon, Peter J., Nitiss, Karin C., Nitiss, John L., Hanakahi, Leslyn A.

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