Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3 von Diehl, Carl, Engström, Olof, Delaine, Tamara, Håkansson, Maria, Genheden, Samuel, Modig, Kristofer, Leffler, Hakon, Ryde, Ulf, Nilsson, Ulf J, Akke, Mikael

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Interplay between Conformational Entropy and Solvation Entropy in Protein–Ligand Binding von Verteramo, Maria Luisa, Stenström, Olof, Ignjatović, Majda Misini, Caldararu, Octav, Olsson, Martin A, Manzoni, Francesco, Leffler, Hakon, Oksanen, Esko, Logan, Derek T, Nilsson, Ulf J, Ryde, Ulf, Akke, Mikael

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Efficient O-Functionalization of Carbohydrates with Electrophilic Reagents von Tolnai, Gergely L., Nilsson, Ulf J., Olofsson, Berit

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The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics von Saraboji, Kadhirvel, Håkansson, Maria, Genheden, Samuel, Diehl, Carl, Qvist, Johan, Weininger, Ulrich, Nilsson, Ulf J, Leffler, Hakon, Ryde, Ulf, Akke, Mikael, Logan, Derek T

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Novel Selective Galectin‑3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia von Bum-Erdene, Khuchtumur, Collins, Patrick M, Hugo, Matthew W, Tarighat, Somayeh S, Fei, Fei, Kishor, Chandan, Leffler, Hakon, Nilsson, Ulf. J, Groffen, John, Grice, I. Darren, Heisterkamp, Nora, Blanchard, Helen

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Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease von Boza-Serrano, Antonio, Ruiz, Rocío, Sanchez-Varo, Raquel, García-Revilla, Juan, Yang, Yiyi, Jimenez-Ferrer, Itzia, Paulus, Agnes, Wennström, Malin, Vilalta, Anna, Allendorf, David, Davila, Jose Carlos, Stegmayr, John, Jiménez, Sebastian, Roca-Ceballos, Maria A., Navarro-Garrido, Victoria, Swanberg, Maria, Hsieh, Christine L., Real, Luis M., Englund, Elisabet, Linse, Sara, Leffler, Hakon, Nilsson, Ulf J., Brown, Guy C., Gutierrez, Antonia, Vitorica, Javier, Venero, Jose Luis, Deierborg, Tomas

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Regulation of Transforming Growth Factor-β1-driven Lung Fibrosis by Galectin-3 von MACKINNON, Alison C, GIBBONS, Michael A, SETHI, Tariq, FARNWORTH, Sarah L, LEFFLER, Hakon, NILSSON, Uif J, DELAINE, Tamara, JOHN SIMPSON, A, FORBES, Stuart J, HIRANI, Nik, GAULDIE, Jack

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Direct sialic acid 4-OAc substitution by nitrogen, sulfur and carbon nucleophiles with retention of stereochemistry von Bozzola, Tiago, Nilsson, Ulf J, Ellervik, Ulf

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Hydrophobic ion pairing of a minocycline/Ca(2+)/AOT complex for preparation of drug-loaded PLGA nanoparticles with improved sustained release von Holmkvist, Alexander Dontsios, Friberg, Annika, Nilsson, Ulf J, Schouenborg, Jens

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Regulation of Alternative Macrophage Activation by Galectin-3 von MacKinnon, Alison C, Farnworth, Sarah L, Hodkinson, Philip S, Henderson, Neil C, Atkinson, Kirsten M, Leffler, Hakon, Nilsson, Ulf J, Haslett, Christopher, Forbes, Stuart J, Sethi, Tariq

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Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition von Delaine, Tamara, Collins, Patrick, MacKinnon, Alison, Sharma, G., Stegmayr, John, Rajput, Vishal K., Mandal, Santanu, Cumpstey, Ian, Larumbe, Amaia, Salameh, Bader A., Kahl-Knutsson, Barbro, van Hattum, Hilde, van Scherpenzeel, Monique, Pieters, Roland J., Sethi, Tariq, Schambye, Hans, Oredsson, Stina, Leffler, Hakon, Blanchard, Helen, Nilsson, Ulf J.

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Galectin‐8 inhibition and functions in immune response and tumor biology von Purić, Edvin, Nilsson, Ulf J., Anderluh, Marko

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Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose and 2′-fucosyllactose von Bum-Erdene, Khuchtumur, Leffler, Hakon, Nilsson, Ulf J., Blanchard, Helen

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Ligand Induced Galectin-3 Protein Self-association von Lepur, Adriana, Salomonsson, Emma, Nilsson, Ulf J., Leffler, Hakon

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Extracellular and intracellular small-molecule galectin-3 inhibitors von Stegmayr, John, Zetterberg, Fredrik, Carlsson, Michael C., Huang, Xiaoli, Sharma, Gunjan, Kahl-Knutson, Barbro, Schambye, Hans, Nilsson, Ulf J., Oredsson, Stina, Leffler, Hakon

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Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans von Stegmayr, John, Lepur, Adriana, Kahl-Knutson, Barbro, Aguilar-Moncayo, Matilde, Klyosov, Anatole A., Field, Robert A., Oredsson, Stina, Nilsson, Ulf J., Leffler, Hakon

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Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis von Chen, Wei-Sheng, Cao, Zhiyi, Leffler, Hakon, Nilsson, Ulf J, Panjwani, Noorjahan

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Regulation of Transforming Growth Factor-beta 1-driven Lung Fibrosis by Galectin-3 von MacKinnon, Alison C., Gibbons, Michael A., Farnworth, Sarah L., Leffler, Hakon, Nilsson, Ulf, Delaine, Tamara, Simpson, A. John, Forbes, Stuart J., Hirani, Nik, Gauldie, Jack, Sethi, Tariq

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Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C von Wallerstein, Johan, Ekberg, Vilhelm, Ignjatović, Majda Misini, Kumar, Rohit, Caldararu, Octav, Peterson, Kristoffer, Wernersson, Sven, Brath, Ulrika, Leffler, Hakon, Oksanen, Esko, Logan, Derek T., Nilsson, Ulf J., Ryde, Ulf, Akke, Mikael

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Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis von Hirani, Nikhil, MacKinnon, Alison C., Nicol, Lisa, Ford, Paul, Schambye, Hans, Pedersen, Anders, Nilsson, Ulf J., Leffler, Hakon, Sethi, Tariq, Tantawi, Susan, Gravelle, Lise, Slack, Robert J., Mills, Ross, Karmakar, Utsa, Humphries, Duncan, Zetterberg, Fredrik, Keeling, Lucy, Paul, Lyn, Molyneaux, Philip L., Li, Feng, Funston, Wendy, Forrest, Ian A., Simpson, A. John, Gibbons, Michael A., Maher, Toby M.

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