Crystal structures of agonist-bound human cannabinoid receptor CB1 von Hua, Tian, Vemuri, Kiran, Nikas, Spyros P., Laprairie, Robert B., Wu, Yiran, Qu, Lu, Pu, Mengchen, Korde, Anisha, Jiang, Shan, Ho, Jo-Hao, Han, Gye Won, Ding, Kang, Li, Xuanxuan, Liu, Haiguang, Hanson, Michael A., Zhao, Suwen, Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie

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Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures von Hua, Tian, Li, Xiaoting, Wu, Lijie, Iliopoulos-Tsoutsouvas, Christos, Wang, Yuxia, Wu, Meng, Shen, Ling, Brust, Christina A., Nikas, Spyros P., Song, Feng, Song, Xiyong, Yuan, Shuguang, Sun, Qianqian, Wu, Yiran, Jiang, Shan, Grim, Travis W., Benchama, Othman, Stahl, Edward L., Zvonok, Nikolai, Zhao, Suwen, Bohn, Laura M., Makriyannis, Alexandros, Liu, Zhi-Jie

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Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats von Spyridakos, Dimitris, Mastrodimou, Niki, Vemuri, Kiran, Ho, Thanh C, Nikas, Spyros P, Makriyannis, Alexandros, Thermos, Kyriaki

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Structural basis for activation of CB1 by an endocannabinoid analog von Krishna Kumar, Kaavya, Robertson, Michael J., Thadhani, Elina, Wang, Haoqing, Suomivuori, Carl-Mikael, Powers, Alexander S., Ji, Lipin, Nikas, Spyros P., Dror, Ron O., Inoue, Asuka, Makriyannis, Alexandros, Skiniotis, Georgios, Kobilka, Brian

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Effects of cannabinoid exposure on short-term memory and medial orbitofrontal cortex function and chemistry in adolescent female rhesus macaques von Kohut, Stephen J, Cao, Lei, Mintzopolous, Dionyssios, Jiang, Shan, Nikas, Spyros P, Makriyannis, Alexandros, Zou, Chun S, Jensen, J Eric, Frederick, Blaise B, Bergman, Jack, Kangas, Brian D

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Chain Substituted Cannabilactones with Selectivity for the CB2 Cannabinoid Receptor von Alapafuja, Shakiru O, Nikas, Spyros P, Ho, Thanh C, Tong, Fei, Benchama, Othman, Makriyannis, Alexandros

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3′-Functionalized Adamantyl Cannabinoid Receptor Probes von Ogawa, Go, Tius, Marcus A, Zhou, Han, Nikas, Spyros P, Halikhedkar, Aneetha, Mallipeddi, Srikrishnan, Makriyannis, Alexandros

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Synthesis of Functionalized Cannabilactones von Liu, Yingpeng, Ho, Thanh C., Baradwan, Mohammed, Lopez-Alberca, Maria Pascual, Iliopoulos-Tsoutsouvas, Christos, Nikas, Spyros P., Makriyannis, Alexandros

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Synthon-based ligand discovery in virtual libraries of over 11 billion compounds von Sadybekov, Arman A., Sadybekov, Anastasiia V., Liu, Yongfeng, Iliopoulos-Tsoutsouvas, Christos, Huang, Xi-Ping, Pickett, Julie, Houser, Blake, Patel, Nilkanth, Tran, Ngan K., Tong, Fei, Zvonok, Nikolai, Jain, Manish K., Savych, Olena, Radchenko, Dmytro S., Nikas, Spyros P., Petasis, Nicos A., Moroz, Yurii S., Roth, Bryan L., Makriyannis, Alexandros, Katritch, Vsevolod

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Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure von Miller, Sally, Kulkarni, Shashank, Ciesielski, Alex, Nikas, Spyros P, Mackie, Ken, Makriyannis, Alexandros, Straiker, Alex

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Crystal structures of agonist-bound human cannabinoid receptor CB 1 von Hua, Tian, Vemuri, Kiran, Nikas, Spyros P, Laprairie, Robert B, Wu, Yiran, Qu, Lu, Pu, Mengchen, Korde, Anisha, Jiang, Shan, Ho, Jo-Hao, Han, Gye Won, Ding, Kang, Li, Xuanxuan, Liu, Haiguang, Hanson, Michael A, Zhao, Suwen, Bohn, Laura M, Makriyannis, Alexandros, Stevens, Raymond C, Liu, Zhi-Jie

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Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201 von AlKhelb, Dalal, Burke, Emily L, Zvonok, Alexander, Iliopoulos-Tsoutsouvas, Christos, Georgiadis, Markos-Orestis, Jiang, Shan, Ho, Thanh C, Nikas, Spyros P, Makriyannis, Alexandros, Desai, Rajeev I

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Differential Enantiomer-Specific Signaling of Cannabidiol at CB1 Receptors von Bosquez-Berger, Taryn, Wilson, Sierra, Iliopoulos-Tsoutsouvas, Christos, Jiang, Shan, Wager-Miller, Jim, Nikas, Spyros P, Mackie, Ken P, Makriyannis, Alexandros, Straiker, Alex

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Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal von Li, Ai-Ling, Lin, Xiaoyan, Dhopeshwarkar, Amey S, Thomaz, Ana Carla, Carey, Lawrence M, Liu, Yingpeng, Nikas, Spyros P, Makriyannis, Alexandros, Mackie, Ken, Hohmann, Andrea G

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Antiemetic Effects of Cannabinoid Agonists in Nonhuman Primates von Wooldridge, Lisa M., Ji, Lipin, Liu, Yingpeng, Nikas, Spyros P., Makriyannis, Alexandros, Bergman, Jack, Kangas, Brian D.

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Probing the Carboxyester Side Chain in Controlled Deactivation (−)‑Δ8‑Tetrahydrocannabinols von Nikas, Spyros P, Sharma, Rishi, Paronis, Carol A, Kulkarni, Shashank, Thakur, Ganesh A, Hurst, Dow, Wood, JodiAnne T, Gifford, Roger S, Rajarshi, Girija, Liu, Yingpeng, Raghav, Jimit Girish, Guo, Jason Jianxin, Järbe, Torbjörn U.C, Reggio, Patricia H, Bergman, Jack, Makriyannis, Alexandros

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Differential Enantiomer-Specific Signaling of Cannabidiol at CB 1 Receptors von Bosquez-Berger, Taryn, Wilson, Sierra, Iliopoulos-Tsoutsouvas, Christos, Jiang, Shan, Wager-Miller, Jim, Nikas, Spyros P, Mackie, Ken P, Makriyannis, Alexandros, Straiker, Alex

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Design and Synthesis of (13S)-Methyl-Substituted Arachidonic Acid Analogues: Templates for Novel Endocannabinoids von Papahatjis, Demetris P., Nahmias, Victoria R., Nikas, Spyros P., Schimpgen, Marion, Makriyannis, Alexandros

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Corrigendum to “Oxa-adamantyl cannabinoids” [Bioorg. Med. Chem. Lett. 38 (2021) 127882] von Ho, Thanh C., Mullins, Joseph J., Tius, Marcus A., Nikas, Spyros P., Tran, Ngan K., Tong, Fei, Zvonok, Nicolai, Makriyannis, Alexandros

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C1‘-Cycloalkyl Side Chain Pharmacophore in Tetrahydrocannabinols von Papahatjis, Demetris P, Nahmias, Victoria R, Nikas, Spyros P, Andreou, Thanos, Alapafuja, Shakiru O, Tsotinis, Andrew, Guo, Jianxin, Fan, Pusheng, Makriyannis, Alexandros

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