Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach von Mokry, Michal, Nijman, Isaäc J, van Dijken, Anja, Benjamins, Rene, Heidstra, Renze, Scheres, Ben, Cuppen, Edwin

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Dutch genome diagnostic laboratories accelerated and improved variant interpretation and increased accuracy by sharing data von Fokkema, Ivo F. A. C., Velde, Kasper J., Slofstra, Mariska K., Ruivenkamp, Claudia A. L., Vogel, Maartje J., Pfundt, Rolph, Blok, Marinus J., Lekanne Deprez, Ronald H., Waisfisz, Quinten, Abbott, Kristin M., Sinke, Richard J., Rahman, Rubayte, Nijman, Isaäc J., Koning, Bart, Thijs, Gert, Wieskamp, Nienke, Moritz, Ruben J. G., Charbon, Bart, Saris, Jasper J., den Dunnen, Johan T., Laros, Jeroen F. J., Swertz, Morris A., Gijn, Marielle E.

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Sambamba: fast processing of NGS alignment formats von Tarasov, Artem, Vilella, Albert J, Cuppen, Edwin, Nijman, Isaac J, Prins, Pjotr

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Maternal and paternal lineages in cross-breeding bovine species. Has wisent a hybrid origin? von Verkaar, Edward L C, Nijman, Isaäc J, Beeke, Maurice, Hanekamp, Eline, Lenstra, Johannes A

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A genome-wide SNP panel for mapping and association studies in the rat von Nijman, Isaäc J, Kuipers, Sylvia, Verheul, Mark, Guryev, Victor, Cuppen, Edwin

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Effector identification in the lettuce downy mildew Bremia lactucae by massively parallel transcriptome sequencing von STASSEN, JOOST H. M., SEIDL, MICHAEL F., VERGEER, PIM W. J., NIJMAN, ISAÄC J., SNEL, BEREND, CUPPEN, EDWIN, VAN DEN ACKERVEKEN, GUIDO

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Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia von Massink, Maarten P.G., Créton, Marijn A., Spanevello, Francesca, Fennis, Willem M.M., Cune, Marco S., Savelberg, Sanne M.C., Nijman, Isaäc J., Maurice, Madelon M., van den Boogaard, Marie-José H., van Haaften, Gijs

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A systematic genome-wide analysis of zebrafish protein-coding gene function von Kettleborough, Ross N. W., Busch-Nentwich, Elisabeth M., Harvey, Steven A., Dooley, Christopher M., de Bruijn, Ewart, van Eeden, Freek, Sealy, Ian, White, Richard J., Herd, Colin, Nijman, Isaac J., Fényes, Fruzsina, Mehroke, Selina, Scahill, Catherine, Gibbons, Richard, Wali, Neha, Carruthers, Samantha, Hall, Amanda, Yen, Jennifer, Cuppen, Edwin, Stemple, Derek L.

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Effectiveness of whole-exome sequencing and costs of the traditional diagnostic trajectory in children with intellectual disability von Monroe, Glen R., Frederix, Gerardus W., Savelberg, Sanne M. C., de Vries, Tamar I., Duran, Karen J., van der Smagt, Jasper J., Terhal, Paulien A., van Hasselt, Peter M., Kroes, Hester Y., Verhoeven-Duif, Nanda M., Nijman, Isaäc J., Carbo, Ellen C., van Gassen, Koen L., Knoers, Nine V., Hövels, Anke M., van Haelst, Mieke M., Visser, Gepke, van Haaften, Gijs

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Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island von van Schaik, Willem, Top, Janetta, Riley, David R, Boekhorst, Jos, Vrijenhoek, Joyce E P, Schapendonk, Claudia M E, Hendrickx, Antoni P A, Nijman, Isaäc J, Bonten, Marc J M, Tettelin, Hervé, Willems, Rob J L

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Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples von Cuppen, Edwin, Nijman, Isaäc J, Mokry, Michal, van Boxtel, Ruben, Toonen, Pim, de Bruijn, Ewart

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Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells von Hatzis, Pantelis, van der Flier, Laurens G., van Driel, Marc A., Guryev, Victor, Nielsen, Fiona, Denissov, Sergei, Nijman, Isaäc J., Koster, Jan, Santo, Evan E., Welboren, Willem, Versteeg, Rogier, Cuppen, Edwin, van de Wetering, Marc, Clevers, Hans, Stunnenberg, Hendrik G.

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Pseudobudding: ruptured glands do not represent true tumor buds von Haddad, Tariq Sami, Dobbelsteen, Luuk, Öztürk, Sonay K, Geene, Robin, Nijman, Isaäc J, Verrijp, Kiek, Jamieson, Nigel B, Wood, Colin, Vliet, Shannon, Reuvers, Luuk, Achouiti, Soumia, Rutgers, Natasja, Brouwer, Nelleke, Simmer, Femke, Zlobec, Inti, Lugli, Alessandro, Nagtegaal, Iris D

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Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer von Kloosterman, Wigard P, Hoogstraat, Marlous, Paling, Oscar, Tavakoli-Yaraki, Masoumeh, Renkens, Ivo, Vermaat, Joost S, van Roosmalen, Markus J, van Lieshout, Stef, Nijman, Isaac J, Roessingh, Wijnand, van’t Slot, Ruben, van de Belt, José, Guryev, Victor, Koudijs, Marco, Voest, Emile, Cuppen, Edwin

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Loss of Syntaxin 3 Causes Variant Microvillus Inclusion Disease von Wiegerinck, Caroline L, Janecke, Andreas R, Schneeberger, Kerstin, Vogel, Georg F, van Haaften–Visser, Désirée Y, Escher, Johanna C, Adam, Rüdiger, Thöni, Cornelia E, Pfaller, Kristian, Jordan, Alexander J, Weis, Cleo–Aron, Nijman, Isaac J, Monroe, Glen R, van Hasselt, Peter M, Cutz, Ernest, Klumperman, Judith, Clevers, Hans, Nieuwenhuis, Edward E.S, Houwen, Roderick H.J, van Haaften, Gijs, Hess, Michael W, Huber, Lukas A, Stapelbroek, Janneke M, Müller, Thomas, Middendorp, Sabine

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Myeloid lineage–restricted somatic mosaicism of NLRP3 mutations in patients with variant Schnitzler syndrome von de Koning, Heleen D., MD, van Gijn, Mariëlle E., MD, PhD, Stoffels, Monique, PhD, Jongekrijg, Johanna, BSc, Zeeuwen, Patrick L.J.M., PhD, Elferink, Martin G., PhD, Nijman, Isaac J., PhD, Jansen, Patrick A.M., PhD, Neveling, Kornelia, PhD, van der Meer, Jos W.M., MD, PhD, Schalkwijk, Joost, PhD, Simon, Anna, MD, PhD

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Tracing the History of Goat Pastoralism: New Clues from Mitochondrial and Y Chromosome DNA in North Africa von Pereira, Filipe, Queirós, Sara, Gusmão, Leonor, Nijman, Isäac J., Cuppen, Edwin, Lenstra, Johannes A., Consortium, Econogene, Davis, Simon J.M., Nejmeddine, Fouad, Amorim, António

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Targeted next-generation sequencing: A novel diagnostic tool for primary immunodeficiencies von Nijman, Isaac J., PhD, van Montfrans, Joris M., MD, PhD, Hoogstraat, Marlous, BAS, Boes, Marianne L., PhD, van de Corput, Lisette, PhD, Renner, Ellen D., MD, PhD, van Zon, Patrick, BSc, van Lieshout, Stef, BSc, Elferink, Martin G., PhD, van der Burg, Mirjam, PhD, Vermont, Clementien L., MD, PhD, van der Zwaag, Bert, PhD, Janson, Esther, BSc, Cuppen, Edwin, PhD, Ploos van Amstel, Johannes K., PhD, van Gijn, Marielle E., PhD

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Heterozygous KIDINS220/ARMS nonsense variants cause spastic paraplegia, intellectual disability, nystagmus, and obesity von Josifova, Dragana J, Monroe, Glen R, Tessadori, Federico, de Graaff, Esther, van der Zwaag, Bert, Mehta, Sarju G, Harakalova, Magdalena, Duran, Karen J, Savelberg, Sanne M C, Nijman, Isaäc J, Jungbluth, Heinz, Hoogenraad, Casper C, Bakkers, Jeroen, Knoers, Nine V, Firth, Helen V, Beales, Philip L, van Haaften, Gijs, van Haelst, Mieke M

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Multiplex spatial omics reveals changes in immune-epithelial crosstalk during inflammation and dysplasia development in chronic IBD patients von Baars, Matthijs J.D., Floor, Evelien, Sinha, Neeraj, ter Linde, José J.M., van Dam, Stephanie, Amini, Mojtaba, Nijman, Isaäc J., ten Hove, Joren R., Drylewicz, Julia, Offerhaus, G.Johan A., Laclé, Miangela M., Oldenburg, Bas, Vercoulen, Yvonne

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