Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3′ UTRs Identified by Cellular Library Screening von Orlandini von Niessen, Alexandra G., Poleganov, Marco A., Rechner, Corina, Plaschke, Arianne, Kranz, Lena M., Fesser, Stephanie, Diken, Mustafa, Löwer, Martin, Vallazza, Britta, Beissert, Tim, Bukur, Valesca, Kuhn, Andreas N., Türeci, Özlem, Sahin, Ugur

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Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes von Brouwers, Olaf, Niessen, Petra M. G., Miyata, Toshio, Østergaard, Jakob A., Flyvbjerg, Allan, Peutz-Kootstra, Carine J., Sieber, Jonas, Mundel, Peter H., Brownlee, Michael, Janssen, Ben J. A., De Mey, Jo G. R., Stehouwer, Coen D. A., Schalkwijk, Casper G.

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Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity von Kern, Matthias, Klöting, Nora, Niessen, Heiko G, Thomas, Leo, Stiller, Detlef, Mark, Michael, Klein, Thomas, Blüher, Matthias

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Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor von Keller, Sascha, Kunz, Ulrich, Schmid, Ulrike, Beusmans, Jack, Büchert, Martin, He, Min, Jayadeva, Girish, Le Tourneau, Christophe, Luedtke, Doreen, Niessen, Heiko G, Oum'hamed, Zohra, Pleiner, Sina, Wang, Xiaoning, Graeser, Ralph

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Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans von Rosqvist, Fredrik, Fridén, Michael, Vessby, Johan, Hockings, Paul, Hulthe, Johannes, Gummesson, Anders, Niessen, Heiko G., Schultheis, Christian, Wanders, Alkwin, Ahlström, Håkan, Rorsman, Fredrik, Risérus, Ulf

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Tryptophan catabolites and depression in the general population: results from the Gutenberg Health Study von Michal, Matthias, Schulz, Andreas, Wild, Philipp S, Koeck, Thomas, Münzel, Thomas, Schuster, Alexander K, Strauch, Konstantin, Lackner, Karl, Süssmuth, Sigurd D, Niessen, Heiko G, Borta, Andreas, Allers, Kelly A, Zahn, Daniela, Beutel, Manfred E

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Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease von Fridén, Michael, Rosqvist, Fredrik, Ahlström, Håkan, Niessen, Heiko G, Schultheis, Christian, Hockings, Paul, Hulthe, Johannes, Gummesson, Anders, Wanders, Alkwin, Rorsman, Fredrik, Risérus, Ulf, Vessby, Johan

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Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db mice von Glund, S., Schoelch, C., Thomas, L., Niessen, H. G., Stiller, D., Roth, G. J., Neubauer, H.

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Design and rationale of the EMPA‐VISION trial: investigating the metabolic effects of empagliflozin in patients with heart failure von Hundertmark, Moritz J., Agbaje, Olorunsola F., Coleman, Ruth, George, Jyothis T., Grempler, Rolf, Holman, Rury R., Lamlum, Hanan, Lee, Jisoo, Milton, Joanne E., Niessen, Heiko G., Rider, Oliver, Rodgers, Christopher T., Valkovič, Ladislav, Wicks, Eleanor, Mahmod, Masliza, Neubauer, Stefan

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Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression von Brouwers, Olaf, de Vos-Houben, Joyce M J, Niessen, Petra M G, Miyata, Toshio, van Nieuwenhoven, Frans, Janssen, Ben J A, Hageman, Geja, Stehouwer, Coen D A, Schalkwijk, Casper G

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The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation von Milaneschi, Yuri, Allers, Kelly A., Beekman, Aartjan T.F., Giltay, Erik J., Keller, Sascha, Schoevers, Robert A., Süssmuth, Sigurd D., Niessen, Heiko G., Penninx, Brenda W.J.H.

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A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons von Braunstein, Kerstin E., Eschbach, Judith, Ròna-Vörös, Krisztina, Soylu, Rana, Mikrouli, Elli, Larmet, Yves, René, Frédérique, De Aguilar, Jose-Luis Gonzalez, Loeffler, Jean-Philippe, Müller, Hans-Peter, Bucher, Selina, Kaulisch, Thomas, Niessen, Heiko G., Tillmanns, Julia, Fischer, Kristina, Schwalenstöcker, Birgit, Kassubek, Jan, Pichler, Bernd, Stiller, Detlef, Petersen, Åsa, Ludolph, Albert C., Dupuis, Luc

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Ventral Striatal D2/3 Receptor Availability Is Associated with Impulsive Choice Behavior As Well As Limbic Corticostriatal Connectivity von Barlow, Rebecca L, Gorges, Martin, Wearn, Alfie, Niessen, Heiko G, Kassubek, Jan, Dalley, Jeffrey W, Pekcec, Anton

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Subfield‐specific Loss of Hippocampal N‐acetyl Aspartate in Temporal Lobe Epilepsy von Vielhaber, Stefan, Niessen, Heiko G., Debska‐Vielhaber, Grazyna, Kudin, Alexei P., Wellmer, Jörg, Kaufmann, Jörn, Schönfeld, Mircea Ariel, Fendrich, Robert, Willker, Wieland, Leibfritz, Dieter, Schramm, Johannes, Elger, Christian E., Heinze, Hans‐Jochen, Kunz, Wolfram S.

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Frequency-dependent activation pattern in the rat hippocampus, a simultaneous electrophysiological and fMRI study von Angenstein, Frank, Kammerer, Elena, Niessen, Heiko G., Frey, Julietta U., Scheich, Henning, Frey, Sabine

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Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis von Calcagno, Claudia, Lairez, Olivier, Hawkins, Julie, Kerr, Steven W., Dugas, Melanie S., Simpson, Thomas, Epskamp, Jelle, Robson, Philip M., Eldib, Mootaz, Bander, Ilda, K-Raman, Purushothaman, Ramachandran, Sarayu, Pruzan, Alison, Kaufman, Audrey, Mani, Venkatesh, Ehlgen, Alexander, Niessen, Heiko G., Broadwater, John, Fayad, Zahi A.

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Advanced magnetic resonance imaging to support clinical drug development for malignant glioma von Kassubek, Rebecca, Müller, Hans-Peter, Thiele, Andrea, Kassubek, Jan, Niessen, Heiko G.

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The Combination of MR Elastography and Proton Density Fat Fraction Improves Diagnosis of Nonalcoholic Steatohepatitis von Alsaqal, Salem, Hockings, Paul, Ahlström, Håkan, Gummesson, Anders, Hedström, Anders, Hulthe, Johannes, Johansson, Lars, Niessen, Heiko G., Schoelch, Corinna, Schultheis, Christian, Vessby, Johan, Wanders, Alkwin, Rorsman, Fredrik, Ebeling Barbier, Charlotte

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Volumetric Magnetic Resonance Imaging of Functionally Relevant Structural Alterations in Chronic Epilepsy after Pilocarpine‐induced Status Epilepticus in Rats von Niessen, Heiko G., Angenstein, Frank, Vielhaber, Stefan, Frisch, Christian, Kudin, Alexei, Elger, Christian E., Heinze, Hans‐Jochen, Scheich, Henning, Kunz, Wolfram S.

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Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis: Integrated Quantification of Plaque Inflammation, Permeability, and Burden During Treatment With a Leukotriene A4 Hydrola... von Calcagno, Claudia, Lairez, Olivier, Hawkins, Julie, Kerr, Steven W, Dugas, Melanie S, Simpson, Thomas, Epskamp, Jelle, Robson, Philip M, Eldib, Mootaz, Bander, Ilda, K-Raman, Purushothaman, Ramachandran, Sarayu, Pruzan, Alison, Kaufman, Audrey, Mani, Venkatesh, Ehlgen, Alexander, Niessen, Heiko G, Broadwater, John, Fayad, Zahi A

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