Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study von Justice, Jamie N., Nambiar, Anoop M., Tchkonia, Tamar, LeBrasseur, Nathan K., Pascual, Rodolfo, Hashmi, Shahrukh K., Prata, Larissa, Masternak, Michal M., Kritchevsky, Stephen B., Musi, Nicolas, Kirkland, James L.

Volltext

Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns von Bhasin, Shalender, Seals, Douglas, Migaud, Marie, Musi, Nicolas, Baur, Joseph A

Volltext

Effect of lipopolysaccharide on inflammation and insulin action in human muscle von Liang, Hanyu, Hussey, Sophie E, Sanchez-Avila, Alicia, Tantiwong, Puntip, Musi, Nicolas

Volltext

NAD-elevating Interventions for Cardiometabolic Disease von Musi, Nicolas

Volltext

Effect of acute TLR4 inhibition on insulin resistance in humans von Liang, Hanyu, Sathavarodom, Nattapol, Colmenares, Claudia, Gelfond, Jonathan, Espinoza, Sara E, Ganapathy, Vinutha, Musi, Nicolas

Volltext

Diabetes and Cardiovascular Disease in Older Adults: Current Status and Future Directions von HALTER, Jeffrey B, MUSI, Nicolas, SCHMADER, Kenneth E, ZIEMAN, Susan, HIGH, Kevin P, MCFARLAND HORNE, Frances, CRANDALL, Jill P, GOLDBERG, Andrew, HARKLESS, Lawrence, HAZZARD, William R, HUANG, Elbert S, SUE KIRKMAN, M, PLUTZKY, Jorge

Volltext

DEP domain–containing mTOR–interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute‐on‐chronic liver injury in alcoholic liver disease von Chen, Hanqing, Shen, Feng, Sherban, Alex, Nocon, Allison, Li, Yu, Wang, Hua, Xu, Ming‐Jiang, Rui, Xianliang, Han, Jinyan, Jiang, Bingbing, Lee, Donghwan, Li, Na, Keyhani‐Nejad, Farnaz, Fan, Jian‐gao, Liu, Feng, Kamat, Amrita, Musi, Nicolas, Guarente, Leonard, Pacher, Pal, Gao, Bin, Zang, Mengwei

Volltext

Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson’s diseases von Song, Chengjie, Zhang, Jun, Qi, Shasha, Liu, Zhen, Zhang, Xiaoyang, Zheng, Yue, Andersen, John‐Paul, Zhang, Weiping, Strong, Randy, Martinez, Paul Anthony, Musi, Nicolas, Nie, Jia, Shi, Yuguang

Volltext

Age‐dependent loss of hepatic SIRT1 enhances NLRP3 inflammasome signaling and impairs capacity for liver fibrosis resolution von Adjei‐Mosi, Jennifer, Sun, Qing, Smithson, Steven Blake, Shealy, Gavyn Lee, Amerineni, Krupa Dhruvitha, Liang, Zerong, Chen, Hanqing, Wang, Mei, Ping, Qinggong, Han, Jingyan, Morita, Masahiro, Kamat, Amrita, Musi, Nicolas, Zang, Mengwei

Volltext

Targeting hepatic serine-arginine protein kinase 2 ameliorates alcohol-associated liver disease by alternative splicing control of lipogenesis von Li, Guannan, Chen, Hanqing, Shen, Feng, Smithson, Steven Blake, Shealy, Gavyn Lee, Ping, Qinggong, Liang, Zerong, Han, Jingyan, Adams, Andrew C, Li, Yu, Feng, Dechun, Gao, Bin, Morita, Masahiro, Han, Xianlin, Huang, Tim H, Musi, Nicolas, Zang, Mengwei

Volltext

Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects von REYNA, Sara M, GHOSH, Sangeeta, MUSI, Nicolas, TANTIWONG, Puntip, REDDY MEKA, C . S, EAGAN, Phyllis, JENKINSON, Christopher P, CERSOSIMO, Eugenio, DEFRONZO, Ralph A, COLETTA, Dawn K, SRIWIJITKAMOL, Apiradee

Volltext

Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? von Bokov, Alex F, Garg, Neha, Ikeno, Yuji, Thakur, Sachin, Musi, Nicolas, DeFronzo, Ralph A, Zhang, Ning, Erickson, Rebecca C, Gelfond, Jon, Hubbard, Gene B, Adamo, Martin L, Richardson, Arlan

Volltext

A low dose lipid infusion is sufficient to induce insulin resistance and a pro-inflammatory response in human subjects von Liang, Hanyu, Lum, Helen, Alvarez, Andrea, Garduno-Garcia, Jose de Jesus, Daniel, Benjamin J, Musi, Nicolas

Volltext

Short-term HIIT impacts HDL function differently in lean, obese, and diabetic subjects von Zhu, Lin, An, Julia, Luu, Thao, Reyna, Sara M, Tantiwong, Puntip, Sriwijitkamol, Apiradee, Musi, Nicolas, Stafford, John M

Volltext

Role of AMP-activated protein kinase in mechanism of metformin action von Zhou, G, Myers, R, Li, Y, Chen, Y, Shen, X, Fenyk-Melody, J, Wu, M, Ventre, J, Doebber, T, Fujii, N, Musi, N, Hirshman, M F, Goodyear, L J, Moller, D E

Volltext

Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model von Patel, Darpan I, Abuchowski, Kira, Bedolla, Roble, Rivas, Paul, Musi, Nicolas, Reddick, Robert, Kumar, A Pratap

Volltext

Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease von Matthews, Ian, Birnbaum, Allison, Gromova, Anastasia, Huang, Amy W., Liu, Kailin, Liu, Eleanor A., Coutinho, Kristen, McGraw, Megan, Patterson, Dalton C., Banks, Macy T., Nobles, Amber C., Nguyen, Nhat, Merrihew, Gennifer E., Wang, Lu, Baeuerle, Eric, Fernandez, Elizabeth, Musi, Nicolas, MacCoss, Michael J., Miranda, Helen C., La Spada, Albert R., Cortes, Constanza J.

Volltext

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy von Lee, Myung-Ja, Feliers, Denis, Mariappan, Meenalakshmi M, Sataranatarajan, Kavithalakshmi, Mahimainathan, Lenin, Musi, Nicolas, Foretz, Marc, Viollet, Benoit, Weinberg, Joel M, Choudhury, Goutam Ghosh, Kasinath, Balakuntalam S

Volltext

AMP-activated protein kinase: role in metabolism and therapeutic implications von Schimmack, Greg, DeFronzo, Ralph A., Musi, Nicolas

Volltext

Pioglitazone Slows Progression of Atherosclerosis in Prediabetes Independent of Changes in Cardiovascular Risk Factors von Saremi, Aramesh, Schwenke, Dawn C, Buchanan, Thomas A, Hodis, Howard N, Mack, Wendy J, Banerji, MaryAnn, Bray, George A, Clement, Stephen C, Henry, Robert R, Kitabchi, Abbas E, Mudaliar, Sunder, Ratner, Robert E, Stentz, Frankie B, Musi, Nicolas, Tripathy, Devjit, DeFronzo, Ralph A, Reaven, Peter D

Volltext