NAV-001, a high-efficacy antibody-drug conjugate targeting mesothelin with improved delivery of a potent payload by counteracting MUC16/CA125 inhibitory effects von Nicolaides, Nicholas C, Kline, J Bradford, Grasso, Luigi

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NAV‐003, a bispecific antibody targeting a unique mesothelin epitope and CD3ε with improved cytotoxicity against humoral immunosuppressed tumors von Grasso, Luigi, Jiang, Qun, Hassan, Raffit, Nicolaides, Nicholas C., Kline, J. Bradford

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Interaction of Endosialin/TEM1 with Extracellular Matrix Proteins Mediates Cell Adhesion and Migration von Tomkowicz, Brian, Rybinski, Katherine, Foley, Brian, Ebel, Wolfgang, Kline, Brad, Routhier, Eric, Sass, Philip, Nicolaides, Nicholas C., Grasso, Luigi, Zhou, Yuhong

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Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature von Rybinski, Katherine, Imtiyaz, Hongxia Z, Mittica, Barrie, Drozdowski, Brian, Fulmer, James, Furuuchi, Keiji, Fernando, Shawn, Henry, Marianne, Chao, Qimin, Kline, Brad, Albone, Earl, Wustner, Jason, Lin, JianMin, Nicolaides, Nicholas C, Grasso, Luigi, Zhou, Yuhong

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The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity von Lin, JianMin, Spidel, Jared L, Maddage, Christopher J, Rybinski, Katherine A, Kennedy, Rina P, Krauthauser, Candice LM, Park, Young Chul, Albone, Earl F, Jacob, Sara, Goserud, Matthew T, Martinez, Bryon P, Chao, Qimin, Zhou, Yuhong, Nicolaides, Nicholas C, Kline, J Bradford, Grasso, Luigi

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Characterization of the human folate receptor alpha via novel antibody-based probes von O'Shannessy, Daniel J, Somers, Elizabeth B, Albone, Earl, Cheng, Xin, Park, Young Chul, Tomkowicz, Brian E, Hamuro, Yoshitomo, Kohl, Thomas O, Forsyth, Tracy M, Smale, Robert, Fu, Yao-Shi, Nicolaides, Nicholas C

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Co-development of diagnostic vectors to support targeted therapies and theranostics: essential tools in personalized cancer therapy von Nicolaides, Nicholas C, O'Shannessy, Daniel J, Albone, Earl, Grasso, Luigi

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Block‑Removed Immunoglobulin Technology to enhance rituximab effector function by counteracting CA125‑mediated immunosuppression von Grasso, Luigi, Kline, James Bradford, Nicolaides, Nicholas C

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Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients von Liu, Bo, Parsons, Ramon, Papadopoulos, Nickolas, Nicolaides, Nicholas C, Lynch, Henry T, Watson, Patrice, Jass, Jeremy R, Dunlop, Malcolm, Wyllie, Andrew, Peltomäki, Païvi, Chapeele, Albert De La, Hamilton, Stanley R, Vocelstein, Bert, Kinzler, Kenneth W

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Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures von Finnberg, Niklas K, Gokare, Prashanth, Lev, Avital, Grivennikov, Sergei I, MacFarlane, 4th, Alexander W, Campbell, Kerry S, Winters, Ryan M, Kaputa, Karen, Farma, Jeffrey M, Abbas, Abbas El-Sayed, Grasso, Luigi, Nicolaides, Nicholas C, El-Deiry, Wafik S

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Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer von Nicolaides, Nicholas C, Papadopoulos, Nickolas, Liu, Bo, Weit, Ying-Fei, Carter, Kenneth C, Ruben, Steven M, Rosen, Craig A, Haseltine, William A, Fleischmann, Robert D, Fraser, Claire M, Adams, Mark D, Venter, J. Craig, Dunlop, Malcolm G, Hamilton, Stanley R, Petersen, Gloria M, de la Chapelle, Albert, Vogelstein, Bert, Kinzler, Kenneth W

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Tumor‐shed antigen CA125 blocks complement‐mediated killing via suppression of C1q‐antibody binding von Kline, J. Bradford, Fernando, Shawn, Ross, Erin N., Grasso, Luigi, Nicolaides, Nicholas C.

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Characterization of a Calcium-Activated Chloride Channel as a Shared Target of Th2 Cytokine Pathways and Its Potential Involvement in Asthma von Zhou, Yuhong, Dong, Qu, Louahed, Jamila, Dragwa, Carl, Savio, Dawn, Huang, Minxue, Weiss, Christine, Tomer, Yaniv, McLane, Michael P, Nicolaides, Nicholas C, Levitt, Roy C

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Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement von Kline, James Bradford, Kennedy, Rina P, Albone, Earl, Chao, Qimin, Fernando, Shawn, McDonough, Jennifer M, Rybinski, Katherine, Wang, Wenquan, Somers, Elizabeth B, Schweizer, Charles, Grasso, Luigi, Nicolaides, Nicholas C

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Interleukin 9: A Candidate Gene for Asthma von Nicolaides, Nicholas C., Holroyd, Kenneth J., Ewart, Susan L., Eleff, Scott M., Kiser, Matthew B., Dragwa, Carl R., Sullivan, Christine D., Grasso, Luigi, Zhang, Liu-Yi, Messler, Carol J., Zhou, Tingyi, Kleeberger, Steven R., Buetow, Kenneth H., Levitt, Roy C.

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Correlation of FCGRT genomic structure with serum immunoglobulin, albumin and farletuzumab pharmacokinetics in patients with first relapsed ovarian cancer von O'Shannessy, Daniel J., Bendas, Katie, Schweizer, Charles, Wang, Wenquan, Albone, Earl, Somers, Elizabeth B., Weil, Susan, Meredith, Rhonda K., Wustner, Jason, Grasso, Luigi, Landers, Mark, Nicolaides, Nicholas C.

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CA125 effects on humoral immunosuppression von Kline, J Bradford, Nicolaides, Nicholas C

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CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients von Nicolaides, Nicholas C, Schweizer, Charles, Somers, Elizabeth B, Wang, Wenquan, Fernando, Shawn, Ross, Erin N, Grasso, Luigi, Hassan, Raffit, Kline, J Bradford

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Human Antibodies for Immunotherapy Development Generated via a Human B Cell Hybridoma Technology von Li, Jian, Sai, Tao, Berger, Marc, Chao, Qimin, Davidson, Diane, Deshmukh, Gaurav, Drozdowski, Brian, Ebel, Wolfgang, Harley, Stephen, Henry, Marianne, Jacob, Sara, Kline, Brad, Lazo, Ella, Rotella, Frank, Routhier, Eric, Rudolph, Kathryn, Sage, Jeaneen, Simon, Paul, Yao, Jun, Zhou, Yuhong, Kavuru, Mani, Bonfield, Tracey, Thomassen, Mary Jane, Sass, Philip M., Nicolaides, Nicholas C., Grasso, Luigi

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Interleukin 9 promotes influx and local maturation of eosinophils von LOUAHED, Jamila, YUHONG ZHOU, LEVITT, Roy C, HACZKU, Angela, MALOY, W. Lee, RANI, Pyapalli U, WEISS, Christine, TOMER, Yaniv, VINK, Anne, RENAULD, Jean-Christophe, VAN SNICK, Jacques, NICOLAIDES, Nicholas C

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