Palimpsest tunnel valleys: evidence for relative timing of advances in an interlobate area of the Laurentide ice sheet von Kehew, Alan E., Nicks, Linda P., Straw, W. Thomas

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Use of Intensive Insulin Therapy for the Management of Glycemic Control in Hospitalized Patients: A Clinical Practice Guideline From the American College of Physicians von QASEEM, Amir, HUMPHREY, Linda L, CHOU, Roger, SNOW, Vincenza, SHEKELLE, Paul

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SARS-CoV-2 evolution during treatment of chronic infection von Kemp, Steven A., Collier, Dami A., Datir, Rawlings P., Ferreira, Isabella A. T. M., Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J., Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E., Briggs, John A. G., van Gils, Marit J., Smith, Kenneth G. C., Bradley, John R., Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D., Goldstein, Richard A., Smielewska, Anna, Skittrall, Jordan P., Gouliouris, Theodore, Goodfellow, Ian G., Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J. R., McCoy, Laura E., Gupta, Ravindra K.

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Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection von Hall, Victoria, Foulkes, Sarah, Insalata, Ferdinando, Kirwan, Peter, Saei, Ayoub, Atti, Ana, Wellington, Edgar, Khawam, Jameel, Munro, Katie, Cole, Michelle, Tranquillini, Caio, Taylor-Kerr, Andrew, Hettiarachchi, Nipunadi, Calbraith, Davina, Sajedi, Noshin, Milligan, Iain, Themistocleous, Yrene, Corrigan, Diane, Cromey, Lisa, Price, Lesley, Stewart, Sally, de Lacy, Elen, Norman, Chris, Linley, Ezra, Otter, Ashley D, Semper, Amanda, Hewson, Jacqueline, D’Arcangelo, Silvia, Chand, Meera, Brown, Colin S, Brooks, Tim, Islam, Jasmin, Charlett, Andre, Hopkins, Susan

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Uterine-Artery Embolization or Myomectomy for Uterine Fibroids von Manyonda, Isaac, Belli, Anna-Maria, Lumsden, Mary-Ann, Moss, Jonathan, McKinnon, William, Middleton, Lee J, Cheed, Versha, Wu, Olivia, Sirkeci, Fusun, Daniels, Jane P, McPherson, Klim

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Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial von Hill, Kevin D., Kannankeril, Prince J., Jacobs, Jeffrey P., Baldwin, H. Scott, Jacobs, Marshall L., O’Brien, Sean M., Bichel, David P., Graham, Eric M., Blasiole, Brian, Resheidat, Ashraf, Husain, Adil S., Kumar, S. Ram, Kirchner, Jerry L., Gallup, Dianne S., Turek, Joseph W., Bleiweis, Mark, Mettler, Bret, Benscoter, Alexis, Wald, Eric, Karamlou, Tara, Van Bergen, Andrew H., Overman, David, Eghtesady, Pirooz, Butts, Ryan, Kim, John S., Scott, John P., Anderson, Brett R., Swartz, Michael F., McConnell, Patrick I., Vener, David F., Li, Jennifer S.

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A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer von Aminkeng, Folefac, Bhavsar, Amit P, Visscher, Henk, Rassekh, Shahrad R, Li, Yuling, Lee, Jong W, Brunham, Liam R, Caron, Huib N, van Dalen, Elvira C, Kremer, Leontien C, van der Pal, Helena J, Amstutz, Ursula, Rieder, Michael J, Bernstein, Daniel, Carleton, Bruce C, Hayden, Michael R, Ross, Colin J D

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Inflammatory biomarkers in Alzheimer's disease plasma von Morgan, Angharad R., Touchard, Samuel, Barkhof, Frederik, Bertram, Lars, Bos, Isabelle, Dobricic, Valerija, Frisoni, Giovanni, Frölich, Lutz, Gabel, Silvey, Kettunen, Petronella, Lleó, Alberto, Martinez-Lage, Pablo, Mecocci, Patrizia, Meersmans, Karen, Molinuevo, José Luis, Peyratout, Gwendoline, Popp, Julius, Richardson, Jill, Scheltens, Philip, Soininen, Hikka, Tsolaki, Magda, Vos, Stephanie, Wahlund, Lars-Olof, Wallin, Anders, Westwood, Sarah, Lovestone, Simon, Bullmore, Edward T., Bhatti, Junaid, Chamberlain, Samuel J., Crofts, Anna L., Foster, Andrew C., Kitzbichler, Manfred G., Lynall, Mary-Ellen, Maurice, Christina, St George Hyslop, Peter, Turner, Lorinda, Vertes, Petra, Widmer, Barry, Williams, Guy B., Morgan, B. Paul, Leckey, Claire A., Morgan, Angharad R., O'Hagan, Caroline, Cavanagh, Jonathan, Deith, Catherine, McColl, Alison, Scouller, Paul, Sutherland, Murray, Khan, Shahid, Murphy, Phil, Patel, Jai, de Boer, Peter, Drevets, Wayne C., Isaac, John, Bhattacharya, Anindya, Carruthers, Nick, Kolb, Hartmuth, Pariante, Carmine M., Cash, Diana, Mondelli, Valeria, Nikkheslat, Naghmeh, Sheridan, Hannah, Simmons, Camilla, Singh, Nisha, Van Loo, Victoria, Vicente-Rodriguez, Marta, Worrell, Courtney, Plath, Niels, Egebjerg, Jan, Gastambide, Francois, Pederson, Jan Torleif, Campbell, Brian, Möller, Thomas, Nelson, Bob, Zorn, Stevin, O'Connor, Jason, Attenburrow, Mary Jane, Baird, Alison, Benjamin, Jithen, Clare, Stuart, Cowen, Philip, Huang, I-Shu (Dante), Jones, Helen, Lovestone, Simon, Mada, Francisca, Oladejo, Akintayo, Ribe, Elena, Smith, Katy, Vyas, Anviti, Sporn, Jonathan, Fryatt, Gemma, Gomez-Nicola, Diego, Mancuso, Renzo, Reynolds, Richard, Cercignani, Mara, Clarke, Charlotte L., Hoskins, Elizabeth, Murray, Rosemary, Wlazly, Dominika, Mount, Howard

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Diagnostic Imaging for Low Back Pain: Advice for High-Value Health Care From the American College of Physicians von CHOU, Roger, QASEEM, Amir, OWENS, Douglas K, SHEKELLE, Paul

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Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children von Pussegoda, K, Ross, C J, Visscher, H, Yazdanpanah, M, Brooks, B, Rassekh, S R, Zada, Y F, Dubé, M-P, Carleton, B C, Hayden, M R

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High-Value, Cost-Conscious Health Care: Concepts for Clinicians to Evaluate the Benefits, Harms, and Costs of Medical Interventions von OWENS, Douglas K, QASEEM, Amir, CHOU, Roger, SHEKELLE, Paul

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Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial von Rapp, Stephen R, Gaussoin, Sarah A, Sachs, Bonnie C, Chelune, Gordon, Supiano, Mark A, Lerner, Alan J, Wadley, Virginia G, Wilson, Valarie M, Fine, Lawrence J, Whittle, Jeff C, Auchus, Alexander P, Beddhu, Srinivasan, Berlowitz, Dan R, Bress, Adam P, Johnson, Karen C, Krousel-Wood, Marie, Martindale-Adams, Jennifer, Miller, Eliza C, Rifkin, Dena E, Snyder, Joni K, Tamariz, Leonardo, Wolfgram, Dawn F, Cleveland, Maryjo L, Yang, Mia, Nichols, Linda O, Bryan, Robert Nick, Reboussin, David M, Williamson, Jeff D, Pajewski, Nicholas M, Rapp, Stephen R, Pajewski, Nicholas M, Auchus, Alexander P, Chelune, Gordon, Cheung, Alfred K, Cleveland, Maryjo L, Coker, Laura H, Crowe, Michael G, Cushman, William C, Cutler, Jeffery A, Davatzikos, Christos, Desiderio, Lisa, Doshi, Jimit, Erus, Guray, Fine, Lawrence J, Gaussoin, Sarah A, Harris, Darrin, Johnson, Karen C, Kimmel, Paul L, Tamura, Manjula K, Launer, Lenore J, Lerner, Alan J, Lewis, Cora E, Martindale-Adams, Jennifer, Moy, Claudia S, Nichols, Linda O, Oparil, Suzanne, Ogrocki, Paula K, Rahman, Mahboob, Nasrallah, Ilya M, Reboussin, David M, Rocco, Michael V, Sachs, Bonnie C, Sink, Kaycee M, Still, Carolyn H, Supiano, Mark A, Snyder, Joni K, Wadley, Virginia G, Walker, Jennifer, Weiner, Daniel E, Whelton, Paul K, Wilson, Valerie M, Woolard, Nancy, Wright, Jackson T, Wright, Clinton B, Williamson, Jeff D, Bryan, R Nick

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Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses von Needham, Edward J, Ren, Alexander L, Digby, Richard J, Norton, Emma J, Ebrahimi, Soraya, Outtrim, Joanne G, Chatfield, Doris A, Manktelow, Anne E, Leibowitz, Maya M, Newcombe, Virginia F J, Doffinger, Rainer, Barcenas-Morales, Gabriela, Fonseca, Claudia, Taussig, Michael J, Burnstein, Rowan M, Samanta, Romit J, Dunai, Cordelia, Sithole, Nyarie, Ashton, Nicholas J, Zetterberg, Henrik, Gisslén, Magnus, Edén, Arden, Marklund, Emelie, Openshaw, Peter J M, Dunning, Jake, Griffiths, Michael J, Cavanagh, Jonathan, Breen, Gerome, Irani, Sarosh R, Elmer, Anne, Kingston, Nathalie, Summers, Charlotte, Bradley, John R, Taams, Leonie S, Michael, Benedict D, Bullmore, Edward T, Smith, Kenneth G C, Lyons, Paul A, Coles, Alasdair J, Menon, David K

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Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial von Abraham, William T, Dr, Adamson, Philip B, MD, Bourge, Robert C, MD, Aaron, Mark F, MD, Costanzo, Maria Rosa, MD, Stevenson, Lynne W, MD, Strickland, Warren, MD, Neelagaru, Suresh, MD, Raval, Nirav, MD, Krueger, Steven, MD, Weiner, Stanislav, MD, Shavelle, David, MD, Jeffries, Bradley, MD, Yadav, Jay S, MD

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Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children von Visscher, H., Ross, C.J.D., Rassekh, S.R., Sandor, G.S.S., Caron, H.N., van Dalen, E.C., Kremer, L.C., van der Pal, H.J., Rogers, P.C., Rieder, M.J., Carleton, B.C., Hayden, M.R.

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Preterm neonates benefit from low prophylactic platelet transfusion threshold despite varying risk of bleeding or death von Fustolo-Gunnink, Susanna F., Fijnvandraat, Karin, van Klaveren, David, Stanworth, Simon J., Curley, Anna, Onland, Wes, Steyerberg, Ewout W., de Kort, Ellen, d'Haens, Esther J., Hulzebos, Christian V., Huisman, Elise J., de Boode, Willem P., Lopriore, Enrico, van der Bom, Johanna G.

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Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress von Tollefson, Angela K., Oberley-Deegan, Rebecca E., Butterfield, Kiel T., Nicks, Michael E., Weaver, Michael R., Remigio, Linda K., Decsesznak, Jessica, Chu, H.W., Bratton, Donna L., Riches, David W., Bowler, Russell P.

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A randomised controlled trial of the clinical effectiveness and cost-effectiveness of different knee prostheses: the Knee Arthroplasty Trial (KAT) von Murray, David W, MacLennan, Graeme S, Breeman, Suzanne, Dakin, Helen A, Johnston, Linda, Campbell, Marion K, Gray, Alastair M, Fiddian, Nick, Fitzpatrick, Ray, Morris, Richard W, Grant, Adrian M

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SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity von Meng, Bo, Choi, Jinwook, Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E.D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Calder, Jo, Canna, Laura, Domingo, Jason, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O’Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Dunmore, Benjamin J., Gräf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, O’Donnell, Ciara, Pointon, Linda, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wylot, Marta, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Hinch, Andrew, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Stefanucci, Luca, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M.D.D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Allison, John, Butcher, Helen, Caputo, Daniela, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Bradley, John R., Smith, Kenneth G.C., Lee, Joo Hyeon, Gupta, Ravindra K.

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Inpatient Glycemic Control: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians von Qaseem, Amir, Chou, Roger, Humphrey, Linda L., Shekelle, Paul, Shekelle, Paul, Chou, Roger, Dallas, Paul, Denberg, Thomas D., Fitterman, Nick, Ann Forciea, Mary, Hopkins, Robert H., Humphrey, Linda L., Mir, Tanveer P., Schünemann, Holger J., Sweet, Donna E., Weinberg, David S.

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