Continuous Clonal Labeling Reveals Small Numbers of Functional Stem Cells in Intestinal Crypts and Adenomas von Kozar, Sarah, Morrissey, Edward, Nicholson, Anna M., van der Heijden, Maartje, Zecchini, Heather I., Kemp, Richard, Tavaré, Simon, Vermeulen, Louis, Winton, Douglas J.

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Intestinal label-retaining cells are secretory precursors expressing Lgr5 von Buczacki, Simon J. A., Zecchini, Heather Ireland, Nicholson, Anna M., Russell, Roslin, Vermeulen, Louis, Kemp, Richard, Winton, Douglas J.

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Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation von Vermeiden, Louis, Morrissey, Edward, van der Heijden, Maartje, Nicholson, Anna M., Sottoriva, Andrea, Buczacki, Simon, Kemp, Richard, Tavaré, Simon, Winton, Douglas J.

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Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium von Nicholson, Anna M., Olpe, Cora, Hoyle, Alice, Thorsen, Ann-Sofie, Rus, Teja, Colombé, Mathilde, Brunton-Sim, Roxanne, Kemp, Richard, Marks, Kate, Quirke, Phil, Malhotra, Shalini, ten Hoopen, Rogier, Ibrahim, Ashraf, Lindskog, Cecilia, Myers, Meagan B., Parsons, Barbara, Tavaré, Simon, Wilkinson, Mark, Morrissey, Edward, Winton, Douglas J.

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Bcl-2 is a critical mediator of intestinal transformation von van der Heijden, Maartje, Zimberlin, Cheryl D., Nicholson, Anna M., Colak, Selcuk, Kemp, Richard, Meijer, Sybren L., Medema, Jan Paul, Greten, Florian R., Jansen, Marnix, Winton, Douglas J., Vermeulen, Louis

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Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor von Nicholson, Anna M, Graham, Trevor A, Simpson, Ashley, Humphries, Adam, Burch, Nicola, Rodriguez-Justo, Manuel, Novelli, Marco, Harrison, Rebecca, Wright, Nicholas A, McDonald, Stuart A C, Jankowski, Janusz A

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Identification of Lineage-Uncommitted, Long-Lived, Label-Retaining Cells in Healthy Human Esophagus and Stomach, and in Metaplastic Esophagus von Pan, Qiuwei, Nicholson, Anna M, Barr, Hugh, Harrison, Lea–Anne, Wilson, George D, Burkert, Julia, Jeffery, Rosemary, Alison, Malcolm R, Looijenga, Leendert, Lin, Wey–Ran, McDonald, Stuart A.C, Wright, Nicholas A, Harrison, Rebecca, Peppelenbosch, Maikel P, Jankowski, Janusz A

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Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis von Galandiuk, Susan, Rodriguez–Justo, Manuel, Jeffery, Rosemary, Nicholson, Anna M, Cheng, Yong, Oukrif, Dahmane, Elia, George, Leedham, Simon J, McDonald, Stuart A.C, Wright, Nicholas A, Graham, Trevor A

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The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands von Lavery, Danielle L, Nicholson, Anna M, Poulsom, Richard, Jeffery, Rosemary, Hussain, Alia, Gay, Laura J, Jankowski, Janusz A, Zeki, Sebastian S, Barr, Hugh, Harrison, Rebecca, Going, James, Kadirkamanathan, Sritharan, Davis, Peter, Underwood, Timothy, Novelli, Marco R, Rodriguez–Justo, Manuel, Shepherd, Neil, Jansen, Marnix, Wright, Nicholas A, McDonald, Stuart A C

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Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo von MILICIC, Anita, HARRISON, Lea-Anne, EAST, Philip, OBSZYNSKA, Jolanta, SANDERS, Scott, PIAZUELO, Elena, SHAW, Jacqui, HARRISON, Rebecca, TOMLINSON, Ian P, MCDONALD, Stuart A. C, WRIGHT, Nicholas A, JANKOWSKI, Janusz A. Z, GOODLAD, Robert A, HARDY, Robert G, NICHOLSON, Anna M, PRESZ, Michal, SIEBER, Oliver, SANTANDER, Sonia, PRINGLE, James H, MANDIR, Nikki

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279 The Stem Cell Organization, and the Proliferative and Gene Expression Profile of Barrett's Epithelium, Indicates Its Origin From Gastric Glands von Lavery, Danielle L, Nicholson, Anna M, Barr, Hugh, Gay, Laura J, Jeffery, Rosemary, Poulsom, Richard, Harrison, Rebecca F, Jankowski, Janusz A, Jansen, Marnix, Novelli, Marco, McDonald, Stuart A, Rodriguez-Justo, Manuel, Shepherd, Neil A, Wright, Nicholas A

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Altered Stem Cell Dynamics in Human Colon Adenoma Crypts Allow Rapid Expansion and Fixation of Mutations During Clonal Expansion von Humphries, Adam, Graham, Trevor A, Nicholson, Anna M, McDonald, Stuart A, Wright, Nicholas A

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947 Analysis of the Clonality of Barrett's Esophagus Glands Reveals They are Clonal Units and Establishes a Common Stem Cell for Glandular and Squamous Epithelium von Nicholson, Anna M, Graham, Trevor A, Simpson, Ashley I, Humphries, Adam, Wright, Nicholas A, McDonald, Stuart A, Jankowski, Janusz A

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M1970 Differential Effects of TNF-α On Oesophageal Cell Lines Along the Metaplasia-Dysplasia-Adenocarcinoma Sequence von Nicholson, Anna M, Arscott, Ramon D, Milicic, Anita, Jankowski, Janusz A

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T1738 Stem Cell Location Throughout the Human Gastrointestinal Tract as Defined by LGR5 mRNA in Situ Hybridisation von McDonald, Stuart A, Jeffery, Rosemary, Humphries, Adam, Leedham, Simon, Graham, Trevor A, Lewis, Annabelle, Segditsas, Stefania, Rodriguez-Justo, Manuel, Nicholson, Anna M, Novelli, Marco, Bamba, Shigeki, Jankowski, Janusz A, Wright, Nicholas A, Poulsom, Richard

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M1620 The Saint Trial (Stem Cell Analysis and Identification By Iudr Labelling of Neoplastic Tissue); Identification of Barrett's Stem Cells von Nicholson, Anna M, Harrison, Lea-Anne, Barr, Hugh, Burkert, Julia, Wilson, George, McDonald, Stuart A, Wright, Nicholas A, Harrison, Rebecca F, Jankowski, Janusz A

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M1969 Expression of Hypoxia Inducible Factor 1α (HIF-1α) in the Progression to Oesophageal Adenocarcinoma: A Key Target for Therapy von Teratani, Naoki, Nicholson, Anna M, Atherfold, Paul A, Milicic, Anita, Jankowski, Janusz A

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Ectopic expression of P-Cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in mice von Milicic, Anita, Harrison, Lea-Anne, Goodlad, Robert A., Hardy, Robert G., Nicholson, Anna M., Presz, Michal, Sieber, Oliver, Santander, Sonia, Pringle, James H., Mandir, Nikki, East, Philip, Obszynska, Jolanta, Sanders, Scott, Piazuelo, Elena, Shaw, Jacqui, Harrison, Rebecca, Tomlinson, Ian P., McDonald, Stuart A. C., Wright, Nicholas A., Jankowski, Janusz A. Z.

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Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium von Nicholson, Anna M, Olpe, Cora, Hoyle, Alice, Thorsen, Ann-Sofie, Rus, Teja, Colombé, Mathilde, Brunton-Sim, Roxanne, Kemp, Richard, Marks, Kate, Quirke, Phil, Malhotra, Shalini, Ten Hoopen, Rogier, Ibrahim, Ashraf, Lindskog, Cecilia, Myers, Meagan B, Parsons, Barbara, Tavaré, Simon, Wilkinson, Mark, Morrissey, Edward, Winton, Douglas J

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Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium von Nicholson, Anna M, Olpe, Cora, Hoyle, Alice, Thorsen, Ann-Sofie, Rus, Teja, Colombe, Mathilde, Brunton-Sim, Roxanne, Kemp, Richard, Marks, Kate, Quirke, Phil, Malhotra, Shalini, ten Hoopen, Rogier, Ibrahim, Ashraf, Lindskog, Cecilia, Myers, Meagan B, Parsons, Barbara, Tavare, Simon, Wilkinson, Mark, Morrissey, Edward, Winton, Douglas J

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