P116 Testing antioxidant and anti-inflammatory therapies in a complex lung tissue model von Singh, T S, Razali, F R, North, M N, Wilkinson, T W, Nicholas, B L N

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Evidence for several waves of global transmission in the seventh cholera pandemic von Mutreja, Ankur, Kim, Dong Wook, Thomson, Nicholas R., Connor, Thomas R., Lee, Je Hee, Kariuki, Samuel, Croucher, Nicholas J., Choi, Seon Young, Harris, Simon R., Lebens, Michael, Niyogi, Swapan Kumar, Kim, Eun Jin, Ramamurthy, T., Chun, Jongsik, Wood, James L. N., Clemens, John D., Czerkinsky, Cecil, Nair, G. Balakrish, Holmgren, Jan, Parkhill, Julian, Dougan, Gordon

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Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study von Battersby, Nicholas J, How, Peter, Moran, Brendan, Stelzner, Sigmar, West, Nicholas P, Branagan, Graham, Strassburg, Joachim, Quirke, Philip, Tekkis, Paris, Pedersen, Bodil Ginnerup, Gudgeon, Mark, Heald, Bill, Brown, Gina

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Conserving large carnivores: dollars and fence von Packer, C., Loveridge, A., Canney, S., Caro, T., Garnett, S.T., Pfeifer, M., Zander, K.K., Swanson, A., MacNulty, D., Balme, G., Bauer, H., Begg, C.M., Begg, K.S., Bhalla, S., Bissett, C., Bodasing, T., Brink, H., Burger, A., Burton, A.C., Clegg, B., Dell, S., Delsink, A., Dickerson, T., Dloniak, S.M., Druce, D., Frank, L., Funston, P., Gichohi, N., Groom, R., Hanekom, C., Heath, B., Hunter, L., DeIongh, H.H., Joubert, C.J., Kasiki, S.M., Kissui, B., Knocker, W., Leathem, B., Lindsey, P.A., Maclennan, S.D., McNutt, J.W., Miller, S.M., Naylor, S., Nel, P., Ng'weno, C., Nicholls, K., Ogutu, J.O., Okot-Omoya, E., Patterson, B.D., Plumptre, A., Salerno, J., Skinner, K., Slotow, R., Sogbohossou, E.A., Stratford, K.J., Winterbach, C., Winterbach, H., Polasky, S.

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A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation von Han, Jiali, Kraft, Peter, Nan, Hongmei, Guo, Qun, Chen, Constance, Qureshi, Abrar, Hankinson, Susan E, Hu, Frank B, Duffy, David L, Zhao, Zhen Zhen, Martin, Nicholas G, Montgomery, Grant W, Hayward, Nicholas K, Thomas, Gilles, Hoover, Robert N, Chanock, Stephen, Hunter, David J

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Metallaphotoredox: The Merger of Photoredox and Transition Metal Catalysis von Chan, Amy Y, Perry, Ian B, Bissonnette, Noah B, Buksh, Benito F, Edwards, Grant A, Frye, Lucas I, Garry, Olivia L, Lavagnino, Marissa N, Li, Beryl X, Liang, Yufan, Mao, Edna, Millet, Agustin, Oakley, James V, Reed, Nicholas L, Sakai, Holt A, Seath, Ciaran P, MacMillan, David W. C

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SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability von Pfister, Sophia X., Ahrabi, Sara, Zalmas, Lykourgos-Panagiotis, Sarkar, Sovan, Aymard, François, Bachrati, Csanád Z., Helleday, Thomas, Legube, Gaëlle, La Thangue, Nicholas B., Porter, Andrew C.G., Humphrey, Timothy C.

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So depression is an inflammatory disease, but where does the inflammation come from? von Berk, Michael, Williams, Lana J, Jacka, Felice N, O'Neil, Adrienne, Pasco, Julie A, Moylan, Steven, Allen, Nicholas B, Stuart, Amanda L, Hayley, Amie C, Byrne, Michelle L, Maes, Michael

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Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction von Biering, Scott B, Akey, David L, Wong, Marcus P, Brown, W Clay, Lo, Nicholas T N, Puerta-Guardo, Henry, Tramontini Gomes de Sousa, Francielle, Wang, Chunling, Konwerski, Jamie R, Espinosa, Diego A, Bockhaus, Nicholas J, Glasner, Dustin R, Li, Jeffrey, Blanc, Sophie F, Juan, Evan Y, Elledge, Stephen J, Mina, Michael J, Beatty, P Robert, Smith, Janet L, Harris, Eva

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An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography von Butryn, Agata, Simon, Philipp S., Aller, Pierre, Hinchliffe, Philip, Massad, Ramzi N., Leen, Gabriel, Tooke, Catherine L., Bogacz, Isabel, Kim, In-Sik, Bhowmick, Asmit, Brewster, Aaron S., Devenish, Nicholas E., Brem, Jürgen, Kamps, Jos J. A. G., Lang, Pauline A., Rabe, Patrick, Axford, Danny, Beale, John H., Davy, Bradley, Ebrahim, Ali, Orlans, Julien, Storm, Selina L. S., Zhou, Tiankun, Owada, Shigeki, Tanaka, Rie, Tono, Kensuke, Evans, Gwyndaf, Owen, Robin L., Houle, Frances A., Sauter, Nicholas K., Schofield, Christopher J., Spencer, James, Yachandra, Vittal K., Yano, Junko, Kern, Jan F., Orville, Allen M.

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Mining the human phenome using allelic scores that index biological intermediates von Evans, David M, Brion, Marie Jo A, Paternoster, Lavinia, Kemp, John P, McMahon, George, Munafò, Marcus, Whitfield, John B, Medland, Sarah E, Montgomery, Grant W, Timpson, Nicholas J, St Pourcain, Beate, Lawlor, Debbie A, Martin, Nicholas G, Dehghan, Abbas, Hirschhorn, Joel, Smith, George Davey

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Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer von Turner, Nicholas C, Ro, Jungsil, André, Fabrice, Loi, Sherene, Verma, Sunil, Iwata, Hiroji, Harbeck, Nadia, Loibl, Sibylle, Huang Bartlett, Cynthia, Zhang, Ke, Giorgetti, Carla, Randolph, Sophia, Koehler, Maria, Cristofanilli, Massimo

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Conserving large populations of lions – the argument for fences has holes von Creel, S, Becker, M. S, Durant, S. M, M'Soka, J, Matandiko, W, Dickman, A. J, Christianson, D, Dröge, E, Mweetwa, T, Pettorelli, N, Rosenblatt, E, Schuette, P, Woodroffe, R, Bashir, S, Beudels‐Jamar, R. C, Blake, S, Borner, M, Breitenmoser, C, Broekhuis, F, Cozzi, G, Davenport, T. R. B, Deutsch, J, Dollar, L, Dolrenry, S, Douglas‐Hamilton, I, Fitzherbert, E, Foley, C, Hazzah, L, Henschel, P, Hilborn, R, Hopcraft, J. G. C, Ikanda, D, Jacobson, A, Joubert, B, Joubert, D, Kelly, M. S, Lichtenfeld, L, Mace, G. M, Milanzi, J, Mitchell, N, Msuha, M, Muir, R, Nyahongo, J, Pimm, S, Purchase, G, Schenck, C, Sillero‐Zubiri, C, Sinclair, A. R. E, Songorwa, A. N, Stanley‐Price, M, Tehou, C. A, Trout, C, Wall, J, Wittemyer, G, Zimmermann, A, Haddad, Nicholas

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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights von Gusev, Alexander, Mancuso, Nicholas, Won, Hyejung, Kousi, Maria, Finucane, Hilary K., Reshef, Yakir, Song, Lingyun, Safi, Alexias, McCarroll, Steven, Neale, Benjamin M., Ophoff, Roel A., O’Donovan, Michael C., Crawford, Gregory E., Geschwind, Daniel H., Katsanis, Nicholas, Sullivan, Patrick F., Pasaniuc, Bogdan, Price, Alkes L.

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Gut microbiome alterations in Alzheimer’s disease von Vogt, Nicholas M., Kerby, Robert L., Dill-McFarland, Kimberly A., Harding, Sandra J., Merluzzi, Andrew P., Johnson, Sterling C., Carlsson, Cynthia M., Asthana, Sanjay, Zetterberg, Henrik, Blennow, Kaj, Bendlin, Barbara B., Rey, Federico E.

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Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled... von Fizazi, Karim, Prof Dr, Scher, Howard I, Prof, Molina, Arturo, MD, Logothetis, Christopher J, Prof, Chi, Kim N, MD, Jones, Robert J, PhD, Staffurth, John N, MD, North, Scott, MD, Vogelzang, Nicholas J, MD, Saad, Fred, Prof, Mainwaring, Paul, MD, Harland, Stephen, MD, Goodman, Oscar B, MD, Sternberg, Cora N, MD, Li, Jin Hui, PhD, Kheoh, Thian, PhD, Haqq, Christopher M, MD, de Bono, Johann S, Prof

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Oral versus Intravenous Antibiotics for Bone and Joint Infection von Li, Ho-Kwong, Rombach, Ines, Zambellas, Rhea, Walker, A. Sarah, McNally, Martin A, Atkins, Bridget L, Lipsky, Benjamin A, Hughes, Harriet C, Bose, Deepa, Kümin, Michelle, Scarborough, Claire, Matthews, Philippa C, Brent, Andrew J, Lomas, Jose, Gundle, Roger, Rogers, Mark, Taylor, Adrian, Angus, Brian, Byren, Ivor, Berendt, Anthony R, Warren, Simon, Fitzgerald, Fiona E, Mack, Damien J.F, Hopkins, Susan, Folb, Jonathan, Reynolds, Helen E, Moore, Elinor, Marshall, Jocelyn, Jenkins, Neil, Moran, Christopher E, Woodhouse, Andrew F, Stafford, Samantha, Seaton, R. Andrew, Vallance, Claire, Hemsley, Carolyn J, Bisnauthsing, Karen, Sandoe, Jonathan A.T, Aggarwal, Ila, Ellis, Simon C, Bunn, Deborah J, Sutherland, Rebecca K, Barlow, Gavin, Cooper, Cushla, Geue, Claudia, McMeekin, Nicola, Briggs, Andrew H, Sendi, Parham, Khatamzas, Elham, Wangrangsimakul, Tri, Wong, T.H. Nicholas, Barrett, Lucinda K, Alvand, Abtin, Old, C. Fraser, Bostock, Jennifer, Paul, John, Cooke, Graham, Thwaites, Guy E, Bejon, Philip, Scarborough, Matthew

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Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19 von Horby, Peter, Mafham, Marion, Linsell, Louise, Bell, Jennifer L, Staplin, Natalie, Emberson, Jonathan R, Wiselka, Martin, Ustianowski, Andrew, Elmahi, Einas, Prudon, Benjamin, Whitehouse, Tony, Felton, Timothy, Williams, John, Faccenda, Jakki, Underwood, Jonathan, Baillie, J Kenneth, Chappell, Lucy C, Faust, Saul N, Jaki, Thomas, Jeffery, Katie, Lim, Wei Shen, Montgomery, Alan, Rowan, Kathryn, Tarning, Joel, Watson, James A, White, Nicholas J, Juszczak, Edmund, Haynes, Richard, Landray, Martin J

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A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy von Ruas, Jorge L., White, James P., Rao, Rajesh R., Kleiner, Sandra, Brannan, Kevin T., Harrison, Brooke C., Greene, Nicholas P., Wu, Jun, Estall, Jennifer L., Irving, Brian A., Lanza, Ian R., Rasbach, Kyle A., Okutsu, Mitsuharu, Nair, K. Sreekumaran, Yan, Zhen, Leinwand, Leslie A., Spiegelman, Bruce M.

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LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step von Mar, Katrina B., Rinkenberger, Nicholas R., Boys, Ian N., Eitson, Jennifer L., McDougal, Matthew B., Richardson, R. Blake, Schoggins, John W.

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