Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse von Niakan, Kathy K., Eggan, Kevin

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Initiation of a conserved trophectoderm program in human, cow and mouse embryos von Gerri, Claudia, McCarthy, Afshan, Alanis-Lobato, Gregorio, Demtschenko, Andrej, Bruneau, Alexandre, Loubersac, Sophie, Fogarty, Norah M. E., Hampshire, Daniel, Elder, Kay, Snell, Phil, Christie, Leila, David, Laurent, Van de Velde, Hilde, Fouladi-Nashta, Ali A., Niakan, Kathy K.

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Human germline genome editing von A Lea, Rebecca, K Niakan, Kathy

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Self-organization of the human embryo in the absence of maternal tissues von Shahbazi, Marta N., Jedrusik, Agnieszka, Vuoristo, Sanna, Recher, Gaelle, Hupalowska, Anna, Bolton, Virginia, Fogarty, Norah M. E., Campbell, Alison, Devito, Liani G., Ilic, Dusko, Khalaf, Yakoub, Niakan, Kathy K., Fishel, Simon, Zernicka-Goetz, Magdalena

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Defining the three cell lineages of the human blastocyst by single-cell RNA-seq von Blakeley, Paul, Fogarty, Norah M E, del Valle, Ignacio, Wamaitha, Sissy E, Hu, Tim Xiaoming, Elder, Kay, Snell, Philip, Christie, Leila, Robson, Paul, Niakan, Kathy K

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Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1 von Regin, Marius, Essahib, Wafaa, Demtschenko, Andrej, Dewandre, Delphine, David, Laurent, Gerri, Claudia, Niakan, Kathy K, Verheyen, Greta, Tournaye, Herman, Sterckx, Johan, Sermon, Karen, Van De Velde, Hilde

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Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease von Hyslop, Louise A., Blakeley, Paul, Craven, Lyndsey, Richardson, Jessica, Fogarty, Norah M. E., Fragouli, Elpida, Lamb, Mahdi, Wamaitha, Sissy E., Prathalingam, Nilendran, Zhang, Qi, O’Keefe, Hannah, Takeda, Yuko, Arizzi, Lucia, Alfarawati, Samer, Tuppen, Helen A., Irving, Laura, Kalleas, Dimitrios, Choudhary, Meenakshi, Wells, Dagan, Murdoch, Alison P., Turnbull, Douglass M., Niakan, Kathy K., Herbert, Mary

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Frequent loss of heterozygosity in CRISPR-Cas9–edited early human embryos von Alanis-Lobato, Gregorio, Zohren, Jasmin, McCarthy, Afshan, Fogarty, Norah M. E., Kubikova, Nada, Hardman, Emily, Greco, Maria, Wells, Dagan, Turner, James M. A., Niakan, Kathy K.

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Defining the three cell lineages of the human blastocyst by single-cell RNA-seq von Blakeley, Paul, Fogarty, Norah M E, Del Valle, Ignacio, Wamaitha, Sissy E, Hu, Tim Xiaoming, Elder, Kay, Snell, Philip, Christie, Leila, Robson, Paul, Niakan, Kathy K

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Human pre-implantation embryo development von Niakan, Kathy K, Han, Jinnuo, Pedersen, Roger A, Simon, Carlos, Pera, Renee A Reijo

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Human Embryogenesis: A Comparative Perspective von Gerri, Claudia, Menchero, Sergio, Mahadevaiah, Shantha K, Turner, James M.A, Niakan, Kathy K

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BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages von Bernardo, Andreia S., Faial, Tiago, Gardner, Lucy, Niakan, Kathy K., Ortmann, Daniel, Senner, Claire E., Callery, Elizabeth M., Trotter, Matthew W., Hemberger, Myriam, Smith, James C., Bardwell, Lee, Moffett, Ashley, Pedersen, Roger A.

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Genome editing reveals a role for OCT4 in human embryogenesis von Fogarty, Norah M. E., McCarthy, Afshan, Snijders, Kirsten E., Powell, Benjamin E., Kubikova, Nada, Blakeley, Paul, Lea, Rebecca, Elder, Kay, Wamaitha, Sissy E., Kim, Daesik, Maciulyte, Valdone, Kleinjung, Jens, Kim, Jin-Soo, Wells, Dagan, Vallier, Ludovic, Bertero, Alessandro, Turner, James M. A., Niakan, Kathy K.

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Human embryo models: the importance of national policy and governance review von Foreman, Amy L, Liddell, Kathleen, Franklin, Sarah, Jackson, Emily, Rozeik, Christina, Niakan, Kathy K

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SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice von Hirota, Takayuki, Blakeley, Paul, Sangrithi, Mahesh N., Mahadevaiah, Shantha K., Encheva, Vesela, Snijders, Ambrosius P., ElInati, Elias, Ojarikre, Obah A., de Rooij, Dirk G., Niakan, Kathy K., Turner, James M.A.

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Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons von Dimos, John T., Rodolfa, Kit T., Niakan, Kathy K., Weisenthal, Laurin M., Mitsumoto, Hiroshi, Chung, Wendy, Croft, Gist F., Saphier, Genevieve, Leibel, Rudy, Goland, Robin, Wichterle, Hynek, Henderson, Christopher E., Eggan, Kevin

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Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells von Wamaitha, Sissy E, del Valle, Ignacio, Cho, Lily T Y, Wei, Yingying, Fogarty, Norah M E, Blakeley, Paul, Sherwood, Richard I, Ji, Hongkai, Niakan, Kathy K

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Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines von Clark, Amander T., Brivanlou, Ali, Fu, Jianping, Kato, Kazuto, Mathews, Debra, Niakan, Kathy K., Rivron, Nicolas, Saitou, Mitinori, Surani, Azim, Tang, Fuchou, Rossant, Janet

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IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche von Wamaitha, Sissy E., Grybel, Katarzyna J., Alanis-Lobato, Gregorio, Gerri, Claudia, Ogushi, Sugako, McCarthy, Afshan, Mahadevaiah, Shantha K., Healy, Lyn, Lea, Rebecca A., Molina-Arcas, Miriam, Devito, Liani G., Elder, Kay, Snell, Phil, Christie, Leila, Downward, Julian, Turner, James M. A., Niakan, Kathy K.

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TRF2-independent chromosome end protection during pluripotency von Ruis, Phil, Van Ly, David, Borel, Valerie, Kafer, Georgia R., McCarthy, Afshan, Howell, Steven, Blassberg, Robert, Snijders, Ambrosius P., Briscoe, James, Niakan, Kathy K., Marzec, Paulina, Cesare, Anthony J., Boulton, Simon J.

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