It's good to know what to BACE the specificity of your inhibitors on von Murray, Aoife, Muñiz-García, Ana, Alić, Ivan, Nižetić, Dean

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RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia von Koschut, David, Ray, Debleena, Li, Zhenhua, Giarin, Emanuela, Groet, Jürgen, Alić, Ivan, Kham, Shirley Kow-Yin, Chng, Wee Joo, Ariffin, Hany, Weinstock, David M., Yeoh, Allen Eng-Juh, Basso, Giuseppe, Nižetić, Dean

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Mechanical Stress Induces a Transient Suppression of Cytokine Secretion in Astrocytes Assessed at the Single‐Cell Level with a High‐Throughput Microfluidic Chip von Shao, Xiaowei, Wang, Chunhua, Wang, Chao, Han, Lei, Han, Yunrui, Nižetić, Dean, Zhang, Yu, Han, Lin

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Cerebral organoids with chromosome 21 trisomy secrete Alzheimer’s disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy von Fertan, Emre, Böken, Dorothea, Murray, Aoife, Danial, John S. H., Lam, Jeff Y. L., Wu, Yunzhao, Goh, Pollyanna A., Alić, Ivan, Cheetham, Matthew R., Lobanova, Evgeniia, Zhang, Yu P., Nižetić, Dean, Klenerman, David

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Total cell N-glycosylation is altered during differentiation of induced pluripotent stem cells to neural stem cells and is disturbed by trisomy 21 von Cindrić, Ana, Vučković, Frano, Murray, Aoife, Klarić, Thomas S., Alić, Ivan, Krištić, Jasminka, Nižetić, Dean, Lauc, Gordan

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Tumorigenesis in Down's syndrome: big lessons from a small chromosome von Nižetić, Dean, Groet, Jürgen

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A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, Frances K., Al-Janabi, Tamara, Hardy, John, Karmiloff-Smith, Annette, Nizetic, Dean, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Strydom, André

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The importance of understanding individual differences in Down syndrome [version 1; peer review: 2 approved] von Karmiloff-Smith, Annette, Al-Janabi, Tamara, D'Souza, Hana, Groet, Jurgen, Massand, Esha, Mok, Kin, Startin, Carla, Fisher, Elizabeth, Hardy, John, Nizetic, Dean, Tybulewicz, Victor, Strydom, Andre

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Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering von Zhang, Kunyu, Chooi, Wai Hon, Liu, Shuang, Chin, Jiah Shin, Murray, Aoife, Nizetic, Dean, Cheng, Du, Chew, Sing Yian

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Megakaryocyte hyperproliferation without GATA1 mutation in foetal liver of a case of Down syndrome with hydrops foetalis von De Vita, Serena, Devoy, Anny, Groet, Juergen, Krušlin, Božo, Kuzmić‐Prusac, Ivana, Nižetić, Dean

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Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain von Alić, Ivan, Goh, Pollyanna A., Murray, Aoife, Portelius, Erik, Gkanatsiou, Eleni, Gough, Gillian, Mok, Kin Y., Koschut, David, Brunmeir, Reinhard, Yeap, Yee Jie, O’Brien, Niamh L., Groet, Jürgen, Shao, Xiaowei, Havlicek, Steven, Dunn, N. Ray, Kvartsberg, Hlin, Brinkmalm, Gunnar, Hithersay, Rosalyn, Startin, Carla, Hamburg, Sarah, Phillips, Margaret, Pervushin, Konstantin, Turmaine, Mark, Wallon, David, Rovelet-Lecrux, Anne, Soininen, Hilkka, Volpi, Emanuela, Martin, Joanne E., Foo, Jia Nee, Becker, David L., Rostagno, Agueda, Ghiso, Jorge, Krsnik, Željka, Šimić, Goran, Kostović, Ivica, Mitrečić, Dinko, Francis, Paul T., Blennow, Kaj, Strydom, Andre, Hardy, John, Zetterberg, Henrik, Nižetić, Dean

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DNA-Methylation Patterns in Trisomy 21 Using Cells from Monozygotic Twins von Sailani, M Reza, Santoni, Federico A, Letourneau, Audrey, Borel, Christelle, Makrythanasis, Periklis, Hibaoui, Youssef, Popadin, Konstantin, Bonilla, Ximena, Guipponi, Michel, Gehrig, Corinne, Vannier, Anne, Carre-Pigeon, Frederique, Feki, Anis, Nizetic, Dean, Antonarakis, Stylianos E

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Intracerebral haemorrhage in Down syndrome: protected or predisposed? von Buss, Lewis, Fisher, Elizabeth, Hardy, John, Nizetic, Dean, Groet, Jurgen, Pulford, Laura, Strydom, André

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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels von Murray, Aoife, Gough, Gillian, Cindrić, Ana, Vučković, Frano, Koschut, David, Borelli, Vincenzo, Petrović, Dražen J, Bekavac, Ana, Plećaš, Ante, Hribljan, Valentina, Brunmeir, Reinhard, Jurić, Julija, Pučić-Baković, Maja, Slana, Anita, Deriš, Helena, Frkatović, Azra, Groet, Jűrgen, O'Brien, Niamh L, Chen, Hong Yu, Yeap, Yee Jie, Delom, Frederic, Havlicek, Steven, Gammon, Luke, Hamburg, Sarah, Startin, Carla, D'Souza, Hana, Mitrečić, Dinko, Kero, Mijana, Odak, Ljubica, Krušlin, Božo, Krsnik, Željka, Kostović, Ivica, Foo, Jia Nee, Loh, Yuin-Han, Dunn, Norris Ray, de la Luna, Susana, Spector, Tim, Barišić, Ingeborg, Thomas, Michael S C, Strydom, Andre, Franceschi, Claudio, Lauc, Gordan, Krištić, Jasminka, Alić, Ivan, Nižetić, Dean

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Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models von Tosh, Justin L., Rhymes, Elena R., Mumford, Paige, Whittaker, Heather T., Pulford, Laura J., Noy, Sue J., Cleverley, Karen, Walker, Matthew C., Tybulewicz, Victor L. J., Wykes, Rob C., Fisher, Elizabeth M. C., Wiseman, Frances K.

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Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome von Strydom, Andre, Heslegrave, Amanda, Startin, Carla M, Mok, Kin Y, Hardy, John, Groet, Jurgen, Nizetic, Dean, Zetterberg, Henrik

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Effects of miR-219/miR-338 on microglia and astrocyte behaviors and astrocyte-oligodendrocyte precursor cell interactions von Nguyen, Lan, Ong, William, Wang, Kai, Wang, Mingfeng, Nizetic, Dean, Chew, Sing

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Validating the Cognitive Scale for Down Syndrome (CS-DS) to Detect Longitudinal Cognitive Decline in Adults With Down Syndrome von Startin, Carla M, Lowe, Bryony, Hamburg, Sarah, Hithersay, Rosalyn, Strydom, Andre

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Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models von Tosh, Justin L., Rhymes, Elena R., Mumford, Paige, Whittaker, Heather T., Pulford, Laura J., Noy, Sue J., Cleverley, Karen, Walker, Matthew C., Tybulewicz, Victor L. J., Wykes, Rob C., Fisher, Elizabeth M. C., Wiseman, Frances K.

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Ultrastructural and dynamic studies of the endosomal compartment in Down syndrome von Botté, Alexandra, Lainé, Jeanne, Xicota, Laura, Heiligenstein, Xavier, Fontaine, Gaëlle, Kasri, Amal, Rivals, Isabelle, Goh, Pollyanna, Faklaris, Orestis, Cossec, Jack-Christophe, Morel, Etienne, Rebillat, Anne-Sophie, Nizetic, Dean, Raposo, Graça, Potier, Marie-Claude

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